4K48A

Structure of the streptococcus pneumoniae leucyl-trna synthetase editing domain
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
183
structure length
183
Chain Sequence
TGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVASLEEKGCGQEKV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase
pubmed doi rcsb
molecule tags Ligase
source organism Streptococcus pneumoniae
molecule keywords Leucine--tRNA ligase
total genus 51
structure length 183
sequence length 183
ec nomenclature ec 6.1.1.4: Leucine--tRNA ligase.
pdb deposition date 2013-04-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.740.10 Alpha Beta Alpha-Beta Complex Isoleucyl-tRNA Synthetase; domain 2 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain 4k48A00
2V0GA 5AGHA 1QU3A 2AJIA 2AJGA 4K48A 1GAXA 3PZ0A 1WNYA 1OBCA 4CQNA 3O0AA 1JZQA 1WKBA 5AGTA 4ARCA 1WZ2A 1WK9A 1WNZA 1FFYA 5AGIA 1JZSA 4ARIA 3ZJVA 4K47A 3PZ6A 2AJHA 1QU2A 3ZGZA 3PZ5A 1WK8A 4AQ7A 2V0CA 5AGRA 1H3NA 1IVSA 2WFGA 1UDZA 5AGSA 1WKAA 3ZJUA 2WFEA 4AS1A 2WFDA 2BYTA 5AGJA 1ILEA 2BTEA 3ZJTA 1UE0A 1OBHA
chains in the Genus database with same CATH superfamily
2V0GA 5AGHA 1QU3A 2AJIA 2AJGA 4K48A 1GAXA 3PZ0A 1WNYA 1OBCA 4CQNA 3O0AA 1JZQA 1WKBA 5AGTA 4ARCA 1WZ2A 1WK9A 1WNZA 1FFYA 5AGIA 1JZSA 4ARIA 3ZJVA 4K47A 3PZ6A 2AJHA 1QU2A 3ZGZA 3PZ5A 1WK8A 4AQ7A 2V0CA 5AGRA 1H3NA 1IVSA 2WFGA 1UDZA 5AGSA 1WKAA 3ZJUA 2WFEA 4AS1A 2WFDA 2BYTA 5AGJA 1ILEA 2BTEA 3ZJTA 1UE0A 1OBHA
chains in the Genus database with same CATH topology
2V0GA 5AGHA 1QU3A 2AJIA 2AJGA 4K48A 1GAXA 3PZ0A 1WNYA 1OBCA 4CQNA 3O0AA 1JZQA 1WKBA 5AGTA 4ARCA 1WZ2A 1WK9A 1WNZA 1FFYA 5AGIA 1JZSA 4ARIA 3ZJVA 4K47A 3PZ6A 2AJHA 1QU2A 3ZGZA 3PZ5A 1WK8A 4AQ7A 2V0CA 5AGRA 1H3NA 1IVSA 2WFGA 1UDZA 5AGSA 1WKAA 3ZJUA 2WFEA 4AS1A 2WFDA 2BYTA 5AGJA 1ILEA 2BTEA 3ZJTA 1UE0A 1OBHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V0G A;  5AGH A;  1QU3 A;  2AJI A;  2AJG A;  4K48 A;  1GAX A;  3PZ0 A;  1WNY A;  1OBC A;  4CQN A;  3O0A A;  1JZQ A;  1WKB A;  5AGT A;  4ARC A;  1WZ2 A;  1WK9 A;  1WNZ A;  1FFY A;  5AGI A;  1JZS A;  4ARI A;  3ZJV A;  4K47 A;  3PZ6 A;  2AJH A;  1QU2 A;  3ZGZ A;  3PZ5 A;  1WK8 A;  4AQ7 A;  2V0C A;  5AGR A;  1H3N A;  1IVS A;  2WFG A;  1UDZ A;  5AGS A;  1WKA A;  3ZJU A;  2WFE A;  4AS1 A;  2WFD A;  2BYT A;  5AGJ A;  1ILE A;  2BTE A;  3ZJT A;  1UE0 A;  1OBH A; 
#chains in the Genus database with same CATH topology
 2V0G A;  5AGH A;  1QU3 A;  2AJI A;  2AJG A;  4K48 A;  1GAX A;  3PZ0 A;  1WNY A;  1OBC A;  4CQN A;  3O0A A;  1JZQ A;  1WKB A;  5AGT A;  4ARC A;  1WZ2 A;  1WK9 A;  1WNZ A;  1FFY A;  5AGI A;  1JZS A;  4ARI A;  3ZJV A;  4K47 A;  3PZ6 A;  2AJH A;  1QU2 A;  3ZGZ A;  3PZ5 A;  1WK8 A;  4AQ7 A;  2V0C A;  5AGR A;  1H3N A;  1IVS A;  2WFG A;  1UDZ A;  5AGS A;  1WKA A;  3ZJU A;  2WFE A;  4AS1 A;  2WFD A;  2BYT A;  5AGJ A;  1ILE A;  2BTE A;  3ZJT A;  1UE0 A;  1OBH A; 
#chains in the Genus database with same CATH homology
 2V0G A;  5AGH A;  1QU3 A;  2AJI A;  2AJG A;  4K48 A;  1GAX A;  3PZ0 A;  1WNY A;  1OBC A;  4CQN A;  3O0A A;  1JZQ A;  1WKB A;  5AGT A;  4ARC A;  1WZ2 A;  1WK9 A;  1WNZ A;  1FFY A;  5AGI A;  1JZS A;  4ARI A;  3ZJV A;  4K47 A;  3PZ6 A;  2AJH A;  1QU2 A;  3ZGZ A;  3PZ5 A;  1WK8 A;  4AQ7 A;  2V0C A;  5AGR A;  1H3N A;  1IVS A;  2WFG A;  1UDZ A;  5AGS A;  1WKA A;  3ZJU A;  2WFE A;  4AS1 A;  2WFD A;  2BYT A;  5AGJ A;  1ILE A;  2BTE A;  3ZJT A;  1UE0 A;  1OBH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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