4K48A

Structure of the streptococcus pneumoniae leucyl-trna synthetase editing domain
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
183
structure length
183
Chain Sequence
TGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVASLEEKGCGQEKV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Ligase
molecule keywords Leucine--tRNA ligase
total genus 51
structure length 183
sequence length 183
ec nomenclature ec 6.1.1.4: Leucine--tRNA ligase.
pdb deposition date 2013-04-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.740.10 Alpha Beta Alpha-Beta Complex Isoleucyl-tRNA Synthetase; domain 2 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain 4k48A00
3O0AA 4ARCA 2WFDA 5AGIA 2V0GA 1OBHA 1WK9A 1UDZA 5AGJA 1WK8A 3ZJUA 3ZJTA 2AJGA 3PZ5A 4ARIA 4K47A 2BTEA 1QU2A 1QU3A 1IVSA 1FFYA 1WKAA 1WNZA 5AGHA 2WFGA 5AGRA 4AQ7A 1GAXA 1WNYA 1H3NA 3ZJVA 1UE0A 2WFEA 3PZ0A 1JZQA 2AJIA 5AGSA 4K48A 5AGTA 3PZ6A 4CQNA 1WKBA 1ILEA 1WZ2A 1OBCA 3ZGZA 2AJHA 4AS1A 1JZSA 2BYTA 2V0CA
chains in the Genus database with same CATH superfamily
3O0AA 4ARCA 2WFDA 5AGIA 2V0GA 1OBHA 1WK9A 1UDZA 5AGJA 1WK8A 3ZJUA 3ZJTA 2AJGA 3PZ5A 4ARIA 4K47A 2BTEA 1QU2A 1QU3A 1IVSA 1FFYA 1WKAA 1WNZA 5AGHA 2WFGA 5AGRA 4AQ7A 1GAXA 1WNYA 1H3NA 3ZJVA 1UE0A 2WFEA 3PZ0A 1JZQA 2AJIA 5AGSA 4K48A 5AGTA 3PZ6A 4CQNA 1WKBA 1ILEA 1WZ2A 1OBCA 3ZGZA 2AJHA 4AS1A 1JZSA 2BYTA 2V0CA
chains in the Genus database with same CATH topology
3O0AA 4ARCA 2WFDA 5AGIA 2V0GA 1OBHA 1WK9A 1UDZA 5AGJA 1WK8A 3ZJUA 3ZJTA 2AJGA 3PZ5A 4ARIA 4K47A 2BTEA 1QU2A 1QU3A 1IVSA 1FFYA 1WKAA 1WNZA 5AGHA 2WFGA 5AGRA 4AQ7A 1GAXA 1WNYA 1H3NA 3ZJVA 1UE0A 2WFEA 3PZ0A 1JZQA 2AJIA 5AGSA 4K48A 5AGTA 3PZ6A 4CQNA 1WKBA 1ILEA 1WZ2A 1OBCA 3ZGZA 2AJHA 4AS1A 1JZSA 2BYTA 2V0CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3O0A A;  4ARC A;  2WFD A;  5AGI A;  2V0G A;  1OBH A;  1WK9 A;  1UDZ A;  5AGJ A;  1WK8 A;  3ZJU A;  3ZJT A;  2AJG A;  3PZ5 A;  4ARI A;  4K47 A;  2BTE A;  1QU2 A;  1QU3 A;  1IVS A;  1FFY A;  1WKA A;  1WNZ A;  5AGH A;  2WFG A;  5AGR A;  4AQ7 A;  1GAX A;  1WNY A;  1H3N A;  3ZJV A;  1UE0 A;  2WFE A;  3PZ0 A;  1JZQ A;  2AJI A;  5AGS A;  4K48 A;  5AGT A;  3PZ6 A;  4CQN A;  1WKB A;  1ILE A;  1WZ2 A;  1OBC A;  3ZGZ A;  2AJH A;  4AS1 A;  1JZS A;  2BYT A;  2V0C A; 
#chains in the Genus database with same CATH topology
 3O0A A;  4ARC A;  2WFD A;  5AGI A;  2V0G A;  1OBH A;  1WK9 A;  1UDZ A;  5AGJ A;  1WK8 A;  3ZJU A;  3ZJT A;  2AJG A;  3PZ5 A;  4ARI A;  4K47 A;  2BTE A;  1QU2 A;  1QU3 A;  1IVS A;  1FFY A;  1WKA A;  1WNZ A;  5AGH A;  2WFG A;  5AGR A;  4AQ7 A;  1GAX A;  1WNY A;  1H3N A;  3ZJV A;  1UE0 A;  2WFE A;  3PZ0 A;  1JZQ A;  2AJI A;  5AGS A;  4K48 A;  5AGT A;  3PZ6 A;  4CQN A;  1WKB A;  1ILE A;  1WZ2 A;  1OBC A;  3ZGZ A;  2AJH A;  4AS1 A;  1JZS A;  2BYT A;  2V0C A; 
#chains in the Genus database with same CATH homology
 3O0A A;  4ARC A;  2WFD A;  5AGI A;  2V0G A;  1OBH A;  1WK9 A;  1UDZ A;  5AGJ A;  1WK8 A;  3ZJU A;  3ZJT A;  2AJG A;  3PZ5 A;  4ARI A;  4K47 A;  2BTE A;  1QU2 A;  1QU3 A;  1IVS A;  1FFY A;  1WKA A;  1WNZ A;  5AGH A;  2WFG A;  5AGR A;  4AQ7 A;  1GAX A;  1WNY A;  1H3N A;  3ZJV A;  1UE0 A;  2WFE A;  3PZ0 A;  1JZQ A;  2AJI A;  5AGS A;  4K48 A;  5AGT A;  3PZ6 A;  4CQN A;  1WKB A;  1ILE A;  1WZ2 A;  1OBC A;  3ZGZ A;  2AJH A;  4AS1 A;  1JZS A;  2BYT A;  2V0C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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