1WKAA

Structural basis for non-cognate amino acid discrimination by the valyl-trna synthetase editing domain
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
143
structure length
143
Chain Sequence
GKLYTLRYEVEGGGFIEIATVRPETVFADQAIAVHPEDERYRHLLGKRARIPLTEVWIPILADPAVEKDFGTGALKVTPAHDPLDYEIGERHGLKPVSVINLEGRMEGERVPEALRGLDRFEARRKAVELFREAGHLVKEEDY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for Non-cognate Amino Acid Discrimination by the Valyl-tRNA Synthetase Editing Domain
pubmed doi rcsb
molecule tags Ligase
source organism Thermus thermophilus
molecule keywords Valyl-tRNA synthetase
total genus 41
structure length 143
sequence length 143
ec nomenclature ec 6.1.1.9: Valine--tRNA ligase.
pdb deposition date 2004-05-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.740.10 Alpha Beta Alpha-Beta Complex Isoleucyl-tRNA Synthetase; domain 2 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain 1wkaA00
2WFDA 1QU2A 3O0AA 1IVSA 4K48A 5AGRA 1ILEA 4ARIA 5AGJA 1UDZA 1GAXA 5AGTA 2AJIA 2V0CA 4AQ7A 1OBHA 3ZJTA 2WFGA 5AGIA 4CQNA 1WNYA 4K47A 5AGSA 1OBCA 2AJGA 3ZGZA 3ZJVA 2AJHA 1QU3A 3ZJUA 1WZ2A 4AS1A 3PZ5A 1WK8A 1JZSA 5AGHA 1UE0A 3PZ0A 1FFYA 1WKBA 2BYTA 2BTEA 1WKAA 1WK9A 4ARCA 1WNZA 1JZQA 2V0GA 3PZ6A 2WFEA 1H3NA
chains in the Genus database with same CATH superfamily
2WFDA 1QU2A 3O0AA 1IVSA 4K48A 5AGRA 1ILEA 4ARIA 5AGJA 1UDZA 1GAXA 5AGTA 2AJIA 2V0CA 4AQ7A 1OBHA 3ZJTA 2WFGA 5AGIA 4CQNA 1WNYA 4K47A 5AGSA 1OBCA 2AJGA 3ZGZA 3ZJVA 2AJHA 1QU3A 3ZJUA 1WZ2A 4AS1A 3PZ5A 1WK8A 1JZSA 5AGHA 1UE0A 3PZ0A 1FFYA 1WKBA 2BYTA 2BTEA 1WKAA 1WK9A 4ARCA 1WNZA 1JZQA 2V0GA 3PZ6A 2WFEA 1H3NA
chains in the Genus database with same CATH topology
2WFDA 1QU2A 3O0AA 1IVSA 4K48A 5AGRA 1ILEA 4ARIA 5AGJA 1UDZA 1GAXA 5AGTA 2AJIA 2V0CA 4AQ7A 1OBHA 3ZJTA 2WFGA 5AGIA 4CQNA 1WNYA 4K47A 5AGSA 1OBCA 2AJGA 3ZGZA 3ZJVA 2AJHA 1QU3A 3ZJUA 1WZ2A 4AS1A 3PZ5A 1WK8A 1JZSA 5AGHA 1UE0A 3PZ0A 1FFYA 1WKBA 2BYTA 2BTEA 1WKAA 1WK9A 4ARCA 1WNZA 1JZQA 2V0GA 3PZ6A 2WFEA 1H3NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WFD A;  1QU2 A;  3O0A A;  1IVS A;  4K48 A;  5AGR A;  1ILE A;  4ARI A;  5AGJ A;  1UDZ A;  1GAX A;  5AGT A;  2AJI A;  2V0C A;  4AQ7 A;  1OBH A;  3ZJT A;  2WFG A;  5AGI A;  4CQN A;  1WNY A;  4K47 A;  5AGS A;  1OBC A;  2AJG A;  3ZGZ A;  3ZJV A;  2AJH A;  1QU3 A;  3ZJU A;  1WZ2 A;  4AS1 A;  3PZ5 A;  1WK8 A;  1JZS A;  5AGH A;  1UE0 A;  3PZ0 A;  1FFY A;  1WKB A;  2BYT A;  2BTE A;  1WKA A;  1WK9 A;  4ARC A;  1WNZ A;  1JZQ A;  2V0G A;  3PZ6 A;  2WFE A;  1H3N A; 
#chains in the Genus database with same CATH topology
 2WFD A;  1QU2 A;  3O0A A;  1IVS A;  4K48 A;  5AGR A;  1ILE A;  4ARI A;  5AGJ A;  1UDZ A;  1GAX A;  5AGT A;  2AJI A;  2V0C A;  4AQ7 A;  1OBH A;  3ZJT A;  2WFG A;  5AGI A;  4CQN A;  1WNY A;  4K47 A;  5AGS A;  1OBC A;  2AJG A;  3ZGZ A;  3ZJV A;  2AJH A;  1QU3 A;  3ZJU A;  1WZ2 A;  4AS1 A;  3PZ5 A;  1WK8 A;  1JZS A;  5AGH A;  1UE0 A;  3PZ0 A;  1FFY A;  1WKB A;  2BYT A;  2BTE A;  1WKA A;  1WK9 A;  4ARC A;  1WNZ A;  1JZQ A;  2V0G A;  3PZ6 A;  2WFE A;  1H3N A; 
#chains in the Genus database with same CATH homology
 2WFD A;  1QU2 A;  3O0A A;  1IVS A;  4K48 A;  5AGR A;  1ILE A;  4ARI A;  5AGJ A;  1UDZ A;  1GAX A;  5AGT A;  2AJI A;  2V0C A;  4AQ7 A;  1OBH A;  3ZJT A;  2WFG A;  5AGI A;  4CQN A;  1WNY A;  4K47 A;  5AGS A;  1OBC A;  2AJG A;  3ZGZ A;  3ZJV A;  2AJH A;  1QU3 A;  3ZJU A;  1WZ2 A;  4AS1 A;  3PZ5 A;  1WK8 A;  1JZS A;  5AGH A;  1UE0 A;  3PZ0 A;  1FFY A;  1WKB A;  2BYT A;  2BTE A;  1WKA A;  1WK9 A;  4ARC A;  1WNZ A;  1JZQ A;  2V0G A;  3PZ6 A;  2WFE A;  1H3N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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