1WNZA

Isoleucyl-trna synthetase editing domain complexed with the post-transfer editing substrate analogue, val-2aa
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
180
structure length
180
Chain Sequence
DPSVYVRFPLKEPKKLGLEKASLLIWTTTPWTLPGNVAAAVHPEYTYAAFQVGDEALILEEGLGRKLLGEGTPVLKTFPGKALEGLPYTPPYPQALEKGYFVVLADYVSQEDGTGIVHQAPAFGAEDLETARVYGLPLLKTVDEEGKLLVEPFKGLYFREANRAILRDLRGRGLLFKEES
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for substrate recognition by the editing domain of isoleucyl-tRNA synthetase
pubmed doi rcsb
molecule tags Ligase
source organism Thermus thermophilus
molecule keywords isoleucyl-trna synthetase
total genus 51
structure length 180
sequence length 180
ec nomenclature ec 6.1.1.5: Isoleucine--tRNA ligase.
pdb deposition date 2004-08-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.740.10 Alpha Beta Alpha-Beta Complex Isoleucyl-tRNA Synthetase; domain 2 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain 1wnzA00
2AJIA 1IVSA 2BTEA 3PZ5A 1QU3A 1WK8A 4ARCA 2WFDA 1JZSA 3O0AA 1WK9A 5AGRA 5AGSA 3ZJUA 1FFYA 4AQ7A 4AS1A 1UDZA 3PZ6A 2AJGA 2V0GA 1WNYA 1WKBA 2AJHA 4CQNA 1UE0A 1QU2A 1OBCA 3ZJVA 3ZGZA 3PZ0A 1WNZA 2WFGA 5AGIA 2V0CA 1ILEA 1GAXA 1WZ2A 5AGTA 5AGHA 4K48A 4ARIA 1WKAA 2WFEA 4K47A 5AGJA 1OBHA 1JZQA 3ZJTA 1H3NA 2BYTA
chains in the Genus database with same CATH superfamily
2AJIA 1IVSA 2BTEA 3PZ5A 1QU3A 1WK8A 4ARCA 2WFDA 1JZSA 3O0AA 1WK9A 5AGRA 5AGSA 3ZJUA 1FFYA 4AQ7A 4AS1A 1UDZA 3PZ6A 2AJGA 2V0GA 1WNYA 1WKBA 2AJHA 4CQNA 1UE0A 1QU2A 1OBCA 3ZJVA 3ZGZA 3PZ0A 1WNZA 2WFGA 5AGIA 2V0CA 1ILEA 1GAXA 1WZ2A 5AGTA 5AGHA 4K48A 4ARIA 1WKAA 2WFEA 4K47A 5AGJA 1OBHA 1JZQA 3ZJTA 1H3NA 2BYTA
chains in the Genus database with same CATH topology
2AJIA 1IVSA 2BTEA 3PZ5A 1QU3A 1WK8A 4ARCA 2WFDA 1JZSA 3O0AA 1WK9A 5AGRA 5AGSA 3ZJUA 1FFYA 4AQ7A 4AS1A 1UDZA 3PZ6A 2AJGA 2V0GA 1WNYA 1WKBA 2AJHA 4CQNA 1UE0A 1QU2A 1OBCA 3ZJVA 3ZGZA 3PZ0A 1WNZA 2WFGA 5AGIA 2V0CA 1ILEA 1GAXA 1WZ2A 5AGTA 5AGHA 4K48A 4ARIA 1WKAA 2WFEA 4K47A 5AGJA 1OBHA 1JZQA 3ZJTA 1H3NA 2BYTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AJI A;  1IVS A;  2BTE A;  3PZ5 A;  1QU3 A;  1WK8 A;  4ARC A;  2WFD A;  1JZS A;  3O0A A;  1WK9 A;  5AGR A;  5AGS A;  3ZJU A;  1FFY A;  4AQ7 A;  4AS1 A;  1UDZ A;  3PZ6 A;  2AJG A;  2V0G A;  1WNY A;  1WKB A;  2AJH A;  4CQN A;  1UE0 A;  1QU2 A;  1OBC A;  3ZJV A;  3ZGZ A;  3PZ0 A;  1WNZ A;  2WFG A;  5AGI A;  2V0C A;  1ILE A;  1GAX A;  1WZ2 A;  5AGT A;  5AGH A;  4K48 A;  4ARI A;  1WKA A;  2WFE A;  4K47 A;  5AGJ A;  1OBH A;  1JZQ A;  3ZJT A;  1H3N A;  2BYT A; 
#chains in the Genus database with same CATH topology
 2AJI A;  1IVS A;  2BTE A;  3PZ5 A;  1QU3 A;  1WK8 A;  4ARC A;  2WFD A;  1JZS A;  3O0A A;  1WK9 A;  5AGR A;  5AGS A;  3ZJU A;  1FFY A;  4AQ7 A;  4AS1 A;  1UDZ A;  3PZ6 A;  2AJG A;  2V0G A;  1WNY A;  1WKB A;  2AJH A;  4CQN A;  1UE0 A;  1QU2 A;  1OBC A;  3ZJV A;  3ZGZ A;  3PZ0 A;  1WNZ A;  2WFG A;  5AGI A;  2V0C A;  1ILE A;  1GAX A;  1WZ2 A;  5AGT A;  5AGH A;  4K48 A;  4ARI A;  1WKA A;  2WFE A;  4K47 A;  5AGJ A;  1OBH A;  1JZQ A;  3ZJT A;  1H3N A;  2BYT A; 
#chains in the Genus database with same CATH homology
 2AJI A;  1IVS A;  2BTE A;  3PZ5 A;  1QU3 A;  1WK8 A;  4ARC A;  2WFD A;  1JZS A;  3O0A A;  1WK9 A;  5AGR A;  5AGS A;  3ZJU A;  1FFY A;  4AQ7 A;  4AS1 A;  1UDZ A;  3PZ6 A;  2AJG A;  2V0G A;  1WNY A;  1WKB A;  2AJH A;  4CQN A;  1UE0 A;  1QU2 A;  1OBC A;  3ZJV A;  3ZGZ A;  3PZ0 A;  1WNZ A;  2WFG A;  5AGI A;  2V0C A;  1ILE A;  1GAX A;  1WZ2 A;  5AGT A;  5AGH A;  4K48 A;  4ARI A;  1WKA A;  2WFE A;  4K47 A;  5AGJ A;  1OBH A;  1JZQ A;  3ZJT A;  1H3N A;  2BYT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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