1XHMB

The crystal structure of a biologically active peptide (sigk) bound to a g protein beta:gamma heterodimer
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
46
structure length
46
Chain Sequence
ASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and Molecular Characterization of a Preferred Protein Interaction Surface on G Protein betagamma Subunits.
pubmed doi rcsb
molecule tags Signaling protein
source organism Bos taurus
molecule keywords Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subun
total genus 12
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2004-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00631 G-gamma GGL domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 1xhmB00
3AH8G 4KFMG 3CIKG 3PVUG 3KRWG 3SN6G 1GOTG 1GP2G 1OMWG 5HE2G 1A0RG 1B9YB 1B9XB 4MK0G 1TBGE 3PSCG 5TDHG 5KDOG 3KRXG 2BCJG 2TRCG 3PVWG 5HE1G 3V5WG 4PNKG 1XHMB 5HE0G 2PBIA 1GG2G 5HE3G
chains in the Genus database with same CATH superfamily
3AH8G 4KFMG 3CIKG 3PVUG 3KRWG 1HFES 3SN6G 1GOTG 1GP2G 1IOJA 1OMWG 5HE2G 1A0RG 1B9YB 1B9XB 4MK0G 1TBGE 3PSCG 5TDHG 5KDOG 3KRXG 2BCJG 2TRCG 3PVWG 5HE1G 3V5WG 4PNKG 1XHMB 5HE0G 2PBIA 1GG2G 5HE3G
chains in the Genus database with same CATH topology
3AH8G 4KFMG 3CIKG 3PVUG 3KRWG 3SN6G 1GOTG 1GP2G 1OMWG 5HE2G 1A0RG 1B9YB 1B9XB 4MK0G 1TBGE 3PSCG 5TDHG 5KDOG 3KRXG 2BCJG 2TRCG 3PVWG 5HE1G 3V5WG 4PNKG 1XHMB 5HE0G 2PBIA 1GG2G 5HE3G
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AH8 G;  4KFM G;  3CIK G;  3PVU G;  3KRW G;  3SN6 G;  1GOT G;  1GP2 G;  1OMW G;  5HE2 G;  1A0R G;  1B9Y B;  1B9X B;  4MK0 G;  1TBG E;  3PSC G;  5TDH G;  5KDO G;  3KRX G;  2BCJ G;  2TRC G;  3PVW G;  5HE1 G;  3V5W G;  4PNK G;  1XHM B;  5HE0 G;  2PBI A;  1GG2 G;  5HE3 G; 
#chains in the Genus database with same CATH topology
 3AH8 G;  4KFM G;  3CIK G;  3PVU G;  3KRW G;  1HFE S;  3SN6 G;  1GOT G;  1GP2 G;  1IOJ A;  1OMW G;  5HE2 G;  1A0R G;  1B9Y B;  1B9X B;  4MK0 G;  1TBG E;  3PSC G;  5TDH G;  5KDO G;  3KRX G;  2BCJ G;  2TRC G;  3PVW G;  5HE1 G;  3V5W G;  4PNK G;  1XHM B;  5HE0 G;  2PBI A;  1GG2 G;  5HE3 G; 
#chains in the Genus database with same CATH homology
 3AH8 G;  4KFM G;  3CIK G;  3PVU G;  3KRW G;  3SN6 G;  1GOT G;  1GP2 G;  1OMW G;  5HE2 G;  1A0R G;  1B9Y B;  1B9X B;  4MK0 G;  1TBG E;  3PSC G;  5TDH G;  5KDO G;  3KRX G;  2BCJ G;  2TRC G;  3PVW G;  5HE1 G;  3V5W G;  4PNK G;  1XHM B;  5HE0 G;  2PBI A;  1GG2 G;  5HE3 G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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