1XHMB

The crystal structure of a biologically active peptide (sigk) bound to a g protein beta:gamma heterodimer
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
46
structure length
46
Chain Sequence
ASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and Molecular Characterization of a Preferred Protein Interaction Surface on G Protein betagamma Subunits.
pubmed doi rcsb
molecule keywords Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subun
molecule tags Signaling protein
source organism Bos taurus
total genus 12
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2004-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00631 G-gamma GGL domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 1xhmB00
3V5WG 1A0RG 5KDOG 3PSCG 1GG2G 1XHMB 1B9YB 1B9XB 3SN6G 2PBIA 1OMWG 4KFMG 5HE3G 3KRWG 1TBGE 5HE0G 5HE1G 3CIKG 4MK0G 4PNKG 3PVUG 1GP2G 1GOTG 5HE2G 3AH8G 2BCJG 3PVWG 5TDHG 2TRCG 3KRXG
chains in the Genus database with same CATH superfamily
3V5WG 1HFES 1A0RG 5KDOG 3PSCG 1GG2G 1XHMB 1B9YB 1B9XB 3SN6G 2PBIA 1OMWG 4KFMG 1IOJA 5HE3G 3KRWG 1TBGE 5HE0G 5HE1G 3CIKG 4MK0G 4PNKG 3PVUG 1GP2G 1GOTG 5HE2G 3AH8G 2BCJG 3PVWG 5TDHG 2TRCG 3KRXG
chains in the Genus database with same CATH topology
3V5WG 1A0RG 5KDOG 3PSCG 1GG2G 1XHMB 1B9YB 1B9XB 3SN6G 2PBIA 1OMWG 4KFMG 5HE3G 3KRWG 1TBGE 5HE0G 5HE1G 3CIKG 4MK0G 4PNKG 3PVUG 1GP2G 1GOTG 5HE2G 3AH8G 2BCJG 3PVWG 5TDHG 2TRCG 3KRXG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3V5W G;  1A0R G;  5KDO G;  3PSC G;  1GG2 G;  1XHM B;  1B9Y B;  1B9X B;  3SN6 G;  2PBI A;  1OMW G;  4KFM G;  5HE3 G;  3KRW G;  1TBG E;  5HE0 G;  5HE1 G;  3CIK G;  4MK0 G;  4PNK G;  3PVU G;  1GP2 G;  1GOT G;  5HE2 G;  3AH8 G;  2BCJ G;  3PVW G;  5TDH G;  2TRC G;  3KRX G; 
#chains in the Genus database with same CATH topology
 3V5W G;  1HFE S;  1A0R G;  5KDO G;  3PSC G;  1GG2 G;  1XHM B;  1B9Y B;  1B9X B;  3SN6 G;  2PBI A;  1OMW G;  4KFM G;  1IOJ A;  5HE3 G;  3KRW G;  1TBG E;  5HE0 G;  5HE1 G;  3CIK G;  4MK0 G;  4PNK G;  3PVU G;  1GP2 G;  1GOT G;  5HE2 G;  3AH8 G;  2BCJ G;  3PVW G;  5TDH G;  2TRC G;  3KRX G; 
#chains in the Genus database with same CATH homology
 3V5W G;  1A0R G;  5KDO G;  3PSC G;  1GG2 G;  1XHM B;  1B9Y B;  1B9X B;  3SN6 G;  2PBI A;  1OMW G;  4KFM G;  5HE3 G;  3KRW G;  1TBG E;  5HE0 G;  5HE1 G;  3CIK G;  4MK0 G;  4PNK G;  3PVU G;  1GP2 G;  1GOT G;  5HE2 G;  3AH8 G;  2BCJ G;  3PVW G;  5TDH G;  2TRC G;  3KRX G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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