1XHMB

The crystal structure of a biologically active peptide (sigk) bound to a g protein beta:gamma heterodimer
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
46
structure length
46
Chain Sequence
ASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subun
publication title Structural and Molecular Characterization of a Preferred Protein Interaction Surface on G Protein betagamma Subunits.
pubmed doi rcsb
source organism Bos taurus
total genus 12
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2004-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00631 G-gamma GGL domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 1xhmB00
3SN6G 1XHMB 4KFMG 1A0RG 5HE1G 2BCJG 1B9XB 3PSCG 5TDHG 5HE3G 1GP2G 3PVUG 5KDOG 5HE2G 3PVWG 1OMWG 2PBIA 1B9YB 4PNKG 1GG2G 2TRCG 4MK0G 3AH8G 3V5WG 1GOTG 1TBGE 3KRXG 3CIKG 5HE0G 3KRWG
chains in the Genus database with same CATH superfamily
3SN6G 1XHMB 4KFMG 1IOJA 1A0RG 1HFES 5HE1G 2BCJG 1B9XB 3PSCG 5TDHG 5HE3G 1GP2G 3PVUG 5KDOG 5HE2G 3PVWG 1OMWG 2PBIA 1B9YB 4PNKG 1GG2G 2TRCG 4MK0G 3AH8G 3V5WG 1GOTG 1TBGE 3KRXG 3CIKG 5HE0G 3KRWG
chains in the Genus database with same CATH topology
3SN6G 1XHMB 4KFMG 1A0RG 5HE1G 2BCJG 1B9XB 3PSCG 5TDHG 5HE3G 1GP2G 3PVUG 5KDOG 5HE2G 3PVWG 1OMWG 2PBIA 1B9YB 4PNKG 1GG2G 2TRCG 4MK0G 3AH8G 3V5WG 1GOTG 1TBGE 3KRXG 3CIKG 5HE0G 3KRWG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SN6 G;  1XHM B;  4KFM G;  1A0R G;  5HE1 G;  2BCJ G;  1B9X B;  3PSC G;  5TDH G;  5HE3 G;  1GP2 G;  3PVU G;  5KDO G;  5HE2 G;  3PVW G;  1OMW G;  2PBI A;  1B9Y B;  4PNK G;  1GG2 G;  2TRC G;  4MK0 G;  3AH8 G;  3V5W G;  1GOT G;  1TBG E;  3KRX G;  3CIK G;  5HE0 G;  3KRW G; 
#chains in the Genus database with same CATH topology
 3SN6 G;  1XHM B;  4KFM G;  1IOJ A;  1A0R G;  1HFE S;  5HE1 G;  2BCJ G;  1B9X B;  3PSC G;  5TDH G;  5HE3 G;  1GP2 G;  3PVU G;  5KDO G;  5HE2 G;  3PVW G;  1OMW G;  2PBI A;  1B9Y B;  4PNK G;  1GG2 G;  2TRC G;  4MK0 G;  3AH8 G;  3V5W G;  1GOT G;  1TBG E;  3KRX G;  3CIK G;  5HE0 G;  3KRW G; 
#chains in the Genus database with same CATH homology
 3SN6 G;  1XHM B;  4KFM G;  1A0R G;  5HE1 G;  2BCJ G;  1B9X B;  3PSC G;  5TDH G;  5HE3 G;  1GP2 G;  3PVU G;  5KDO G;  5HE2 G;  3PVW G;  1OMW G;  2PBI A;  1B9Y B;  4PNK G;  1GG2 G;  2TRC G;  4MK0 G;  3AH8 G;  3V5W G;  1GOT G;  1TBG E;  3KRX G;  3CIK G;  5HE0 G;  3KRW G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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