1YLUA

The structure of e. coli nitroreductase with bound acetate, crystal form 2
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
216
structure length
216
Chain Sequence
DIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKGRKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKEKGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords Oxygen-insensitive NAD(P)H nitroreductase
total genus 73
structure length 216
sequence length 216
chains with identical sequence B
ec nomenclature ec 1.5.1.34: 6,7-dihydropteridine reductase.
pdb deposition date 2005-01-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00881 Nitroreductase Nitroreductase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.109.10 Alpha Beta 3-Layer(aba) Sandwich NADH Oxidase NADH Oxidase 1yluA00
3BM2A 4BN6A 3GBHA 3TO0A 1ICVA 1ICUA 2BKJA 3E39A 3GH8A 4QLYA 5HEIA 5J6CA 1OONA 2WZWA 3GFDA 1OO5A 4DN2A 3M5KA 3KWKA 1BKJA 3GAGA 2ISJA 1ZCHA 3QDLA 3EOFA 1VFRA 3HOIA 2WZVA 3OF4A 1NECA 3TNZA 2R01A 3BM1A 2ISKA 4BNBA 1OOQA 1YLUA 3PXVA 1V5YA 4XOMA 1NOXA 2WQFA 3GE6A 1IDTA 2H0UA 3GB5A 1KQCA 3EK3A 2ISLA 1F5VA 2FREA 3H4OA 3E10A 3HZNA 1KQDA 3G14A 3HJ9A 4G8SA 2HAYA 5KO7A 1OO6A 1V5ZA 2B67A 3X22A 2I7HA 1YKIA 1ICRA 4TTCA 4XOOA 1DS7A 2YMVA 1YLRA 3KOQA 3EO7A 5KO8A 4QLXA 3EO8A 2IFAA 3N2SA 4BN9A 3GR3A 3X21A 4XOQA 5KRDA 3K6HA 1YWQA 3GE5A 5HDJA 4TTBA 1KQBA 4EO3A 1VKWA 3GFAA 4BN8A 4URPA 3BEMA 4BN7A
chains in the Genus database with same CATH superfamily
3BM2A 4BN6A 3GBHA 1J6RA 1ICVA 3TO0A 1ICUA 2BKJA 3E39A 3GH8A 4QLYA 5HEIA 5J6CA 1OONA 2WZWA 3GFDA 1OO5A 4DN2A 3M5KA 3KWKA 1BKJA 3GAGA 2ISJA 1ZCHA 3QDLA 3EOFA 1VFRA 3HOIA 2WZVA 3OF4A 1NECA 3TNZA 2R01A 3BM1A 2ISKA 4BNBA 1OOQA 1YLUA 3PXVA 1V5YA 4XOMA 1NOXA 2WQFA 3GE6A 1IDTA 2H0UA 3GB5A 1KQCA 3EK3A 2ISLA 1F5VA 2FREA 3H4OA 3E10A 3HZNA 1KQDA 3G14A 3HJ9A 4G8SA 2HAYA 5KO7A 1OO6A 1V5ZA 2B67A 3X22A 2I7HA 1YKIA 1ICRA 4TTCA 4XOOA 1DS7A 2YMVA 1YLRA 3KOQA 3EO7A 5KO8A 4QLXA 3EO8A 2IFAA 3N2SA 4BN9A 3GR3A 3X21A 4XOQA 5KRDA 3K6HA 1YWQA 3GE5A 5HDJA 4TTBA 1KQBA 4EO3A 1VKWA 3GFAA 4BN8A 4URPA 3BEMA 4BN7A
chains in the Genus database with same CATH topology
3BM2A 4BN6A 3GBHA 1J6RA 1ICVA 3TO0A 1ICUA 2BKJA 3E39A 3GH8A 4QLYA 5HEIA 5J6CA 1OONA 2WZWA 3GFDA 1OO5A 4DN2A 3M5KA 3KWKA 1BKJA 3GAGA 2ISJA 1ZCHA 3QDLA 3EOFA 1VFRA 3HOIA 2WZVA 3OF4A 1NECA 3TNZA 2R01A 3BM1A 2ISKA 4BNBA 1OOQA 1YLUA 3PXVA 1V5YA 4XOMA 1NOXA 2WQFA 3GE6A 1IDTA 2H0UA 3GB5A 1KQCA 3EK3A 2ISLA 1F5VA 2FREA 3H4OA 3E10A 3HZNA 1KQDA 3G14A 3HJ9A 4G8SA 2HAYA 5KO7A 1OO6A 1V5ZA 2B67A 3X22A 2I7HA 1YKIA 1ICRA 4TTCA 4XOOA 1DS7A 2YMVA 1YLRA 3KOQA 3EO7A 5KO8A 4QLXA 3EO8A 2IFAA 3N2SA 4BN9A 3GR3A 3X21A 4XOQA 5KRDA 3K6HA 1YWQA 3GE5A 5HDJA 4TTBA 1KQBA 4EO3A 1VKWA 3GFAA 4BN8A 4URPA 3BEMA 4BN7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BM2 A;  4BN6 A;  3GBH A;  3TO0 A;  1ICV A;  1ICU A;  2BKJ A;  3E39 A;  3GH8 A;  4QLY A;  5HEI A;  5J6C A;  1OON A;  2WZW A;  3GFD A;  1OO5 A;  4DN2 A;  3M5K A;  3KWK A;  1BKJ A;  3GAG A;  2ISJ A;  1ZCH A;  3QDL A;  3EOF A;  1VFR A;  3HOI A;  2WZV A;  3OF4 A;  1NEC A;  3TNZ A;  2R01 A;  3BM1 A;  2ISK A;  4BNB A;  1OOQ A;  1YLU A;  3PXV A;  1V5Y A;  4XOM A;  1NOX A;  2WQF A;  3GE6 A;  1IDT A;  2H0U A;  3GB5 A;  1KQC A;  3EK3 A;  2ISL A;  1F5V A;  2FRE A;  3H4O A;  3E10 A;  3HZN A;  1KQD A;  3G14 A;  3HJ9 A;  4G8S A;  2HAY A;  5KO7 A;  1OO6 A;  1V5Z A;  2B67 A;  3X22 A;  2I7H A;  1YKI A;  1ICR A;  4TTC A;  4XOO A;  1DS7 A;  2YMV A;  1YLR A;  3KOQ A;  3EO7 A;  5KO8 A;  4QLX A;  3EO8 A;  2IFA A;  3N2S A;  4BN9 A;  3GR3 A;  3X21 A;  4XOQ A;  5KRD A;  3K6H A;  1YWQ A;  3GE5 A;  5HDJ A;  4TTB A;  1KQB A;  4EO3 A;  1VKW A;  3GFA A;  4BN8 A;  4URP A;  3BEM A;  4BN7 A; 
#chains in the Genus database with same CATH topology
 3BM2 A;  4BN6 A;  3GBH A;  1J6R A;  1ICV A;  3TO0 A;  1ICU A;  2BKJ A;  3E39 A;  3GH8 A;  4QLY A;  5HEI A;  5J6C A;  1OON A;  2WZW A;  3GFD A;  1OO5 A;  4DN2 A;  3M5K A;  3KWK A;  1BKJ A;  3GAG A;  2ISJ A;  1ZCH A;  3QDL A;  3EOF A;  1VFR A;  3HOI A;  2WZV A;  3OF4 A;  1NEC A;  3TNZ A;  2R01 A;  3BM1 A;  2ISK A;  4BNB A;  1OOQ A;  1YLU A;  3PXV A;  1V5Y A;  4XOM A;  1NOX A;  2WQF A;  3GE6 A;  1IDT A;  2H0U A;  3GB5 A;  1KQC A;  3EK3 A;  2ISL A;  1F5V A;  2FRE A;  3H4O A;  3E10 A;  3HZN A;  1KQD A;  3G14 A;  3HJ9 A;  4G8S A;  2HAY A;  5KO7 A;  1OO6 A;  1V5Z A;  2B67 A;  3X22 A;  2I7H A;  1YKI A;  1ICR A;  4TTC A;  4XOO A;  1DS7 A;  2YMV A;  1YLR A;  3KOQ A;  3EO7 A;  5KO8 A;  4QLX A;  3EO8 A;  2IFA A;  3N2S A;  4BN9 A;  3GR3 A;  3X21 A;  4XOQ A;  5KRD A;  3K6H A;  1YWQ A;  3GE5 A;  5HDJ A;  4TTB A;  1KQB A;  4EO3 A;  1VKW A;  3GFA A;  4BN8 A;  4URP A;  3BEM A;  4BN7 A; 
#chains in the Genus database with same CATH homology
 3BM2 A;  4BN6 A;  3GBH A;  1J6R A;  1ICV A;  3TO0 A;  1ICU A;  2BKJ A;  3E39 A;  3GH8 A;  4QLY A;  5HEI A;  5J6C A;  1OON A;  2WZW A;  3GFD A;  1OO5 A;  4DN2 A;  3M5K A;  3KWK A;  1BKJ A;  3GAG A;  2ISJ A;  1ZCH A;  3QDL A;  3EOF A;  1VFR A;  3HOI A;  2WZV A;  3OF4 A;  1NEC A;  3TNZ A;  2R01 A;  3BM1 A;  2ISK A;  4BNB A;  1OOQ A;  1YLU A;  3PXV A;  1V5Y A;  4XOM A;  1NOX A;  2WQF A;  3GE6 A;  1IDT A;  2H0U A;  3GB5 A;  1KQC A;  3EK3 A;  2ISL A;  1F5V A;  2FRE A;  3H4O A;  3E10 A;  3HZN A;  1KQD A;  3G14 A;  3HJ9 A;  4G8S A;  2HAY A;  5KO7 A;  1OO6 A;  1V5Z A;  2B67 A;  3X22 A;  2I7H A;  1YKI A;  1ICR A;  4TTC A;  4XOO A;  1DS7 A;  2YMV A;  1YLR A;  3KOQ A;  3EO7 A;  5KO8 A;  4QLX A;  3EO8 A;  2IFA A;  3N2S A;  4BN9 A;  3GR3 A;  3X21 A;  4XOQ A;  5KRD A;  3K6H A;  1YWQ A;  3GE5 A;  5HDJ A;  4TTB A;  1KQB A;  4EO3 A;  1VKW A;  3GFA A;  4BN8 A;  4URP A;  3BEM A;  4BN7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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