1HLOA

The crystal structure of an intact human max-dna complex: new insights into mechanisms of transcriptional control
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
80
structure length
80
Chain Sequence
NDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of an intact human Max-DNA complex: new insights into mechanisms of transcriptional control.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords DNA (5'-D(*CP*AP*CP*CP*AP*CP*GP*TP*GP*GP*T)-3')
total genus 30
structure length 80
sequence length 80
chains with identical sequence B
ec nomenclature
pdb deposition date 1997-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 1hloA00
1NKPB 1NKPA 1AN2A 5I4ZA 4F3LB 4F3LA 4ATKA 1AM9A 3U5VA 1AN4A 2MH3A 4H10B 5I50A 5EYOA 2QL2B 4H10A 4AYAA 2YPAB 2QL2A 1HLOA 4ATIA 1R05A 1MDYB 1UKLC 2YPAA 2YPBB 1MDYA 1NLWB 2LFHA 3MUJA 1A0AA 2YPBA 1NLWA 4ATHA
chains in the Genus database with same CATH superfamily
1NKPB 1NKPA 1AN2A 5I4ZA 4F3LB 4F3LA 4ATKA 1AM9A 3U5VA 1AN4A 2MH3A 4H10B 5I50A 5EYOA 2QL2B 4H10A 4AYAA 2YPAB 2QL2A 1HLOA 4ATIA 1R05A 1MDYB 1UKLC 2YPAA 2YPBB 1MDYA 1ZZAA 1NLWB 2LFHA 3MUJA 1A0AA 2YPBA 1NLWA 4ATHA 1K1FA
chains in the Genus database with same CATH topology
1NKPB 1NKPA 1AN2A 5I4ZA 4F3LB 4F3LA 4ATKA 1AM9A 3U5VA 1AN4A 2MH3A 4H10B 5I50A 5EYOA 2QL2B 4H10A 4AYAA 2YPAB 2QL2A 1HLOA 4ATIA 1R05A 1MDYB 1UKLC 2YPAA 2YPBB 1MDYA 1NLWB 2LFHA 3MUJA 1A0AA 2YPBA 1NLWA 4ATHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NKP B;  1NKP A;  1AN2 A;  5I4Z A;  4F3L B;  4F3L A;  4ATK A;  1AM9 A;  3U5V A;  1AN4 A;  2MH3 A;  4H10 B;  5I50 A;  5EYO A;  2QL2 B;  4H10 A;  4AYA A;  2YPA B;  2QL2 A;  1HLO A;  4ATI A;  1R05 A;  1MDY B;  1UKL C;  2YPA A;  2YPB B;  1MDY A;  1NLW B;  2LFH A;  3MUJ A;  1A0A A;  2YPB A;  1NLW A;  4ATH A; 
#chains in the Genus database with same CATH topology
 1NKP B;  1NKP A;  1AN2 A;  5I4Z A;  4F3L B;  4F3L A;  4ATK A;  1AM9 A;  3U5V A;  1AN4 A;  2MH3 A;  4H10 B;  5I50 A;  5EYO A;  2QL2 B;  4H10 A;  4AYA A;  2YPA B;  2QL2 A;  1HLO A;  4ATI A;  1R05 A;  1MDY B;  1UKL C;  2YPA A;  2YPB B;  1MDY A;  1ZZA A;  1NLW B;  2LFH A;  3MUJ A;  1A0A A;  2YPB A;  1NLW A;  4ATH A;  1K1F A; 
#chains in the Genus database with same CATH homology
 1NKP B;  1NKP A;  1AN2 A;  5I4Z A;  4F3L B;  4F3L A;  4ATK A;  1AM9 A;  3U5V A;  1AN4 A;  2MH3 A;  4H10 B;  5I50 A;  5EYO A;  2QL2 B;  4H10 A;  4AYA A;  2YPA B;  2QL2 A;  1HLO A;  4ATI A;  1R05 A;  1MDY B;  1UKL C;  2YPA A;  2YPB B;  1MDY A;  1NLW B;  2LFH A;  3MUJ A;  1A0A A;  2YPB A;  1NLW A;  4ATH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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