1MDYB

Crystal structure of myod bhlh domain bound to dna: perspectives on dna recognition and implications for transcriptional activation
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
62
structure length
62
Chain Sequence
TTNADRRKAATMRERRRLSKVNEAFETLKRSTSSNPNQRLPKVEILRNAIRYIEGLQALLRD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of MyoD bHLH domain-DNA complex: perspectives on DNA recognition and implications for transcriptional activation.
pubmed doi rcsb
molecule tags Transcription/dna
molecule keywords DNA (5'-D(*TP*CP*AP*AP*CP*AP*GP*CP*TP*GP*TP*TP*GP*A)-3')
total genus 22
structure length 62
sequence length 62
chains with identical sequence C, D
ec nomenclature
pdb deposition date 1994-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 1mdyB00
3MUJA 2QL2B 4H10A 1NKPA 5I50A 2YPBB 2QL2A 4ATKA 4AYAA 4F3LB 3U5VA 2YPBA 1AN4A 1AN2A 4F3LA 2YPAB 1HLOA 5I4ZA 1NLWB 5EYOA 1MDYB 1R05A 2YPAA 1A0AA 4ATHA 4ATIA 1AM9A 2LFHA 1UKLC 4H10B 1NLWA 2MH3A 1MDYA 1NKPB
chains in the Genus database with same CATH superfamily
3MUJA 2QL2B 4H10A 1NKPA 5I50A 2YPBB 1K1FA 2QL2A 4ATKA 4AYAA 4F3LB 1ZZAA 3U5VA 2YPBA 1AN4A 1AN2A 4F3LA 2YPAB 1HLOA 5I4ZA 1NLWB 5EYOA 1MDYB 1R05A 2YPAA 1A0AA 4ATHA 4ATIA 1AM9A 2LFHA 1UKLC 4H10B 1NLWA 2MH3A 1MDYA 1NKPB
chains in the Genus database with same CATH topology
3MUJA 2QL2B 4H10A 1NKPA 5I50A 2YPBB 2QL2A 4ATKA 4AYAA 4F3LB 3U5VA 2YPBA 1AN4A 1AN2A 4F3LA 2YPAB 1HLOA 5I4ZA 1NLWB 5EYOA 1MDYB 1R05A 2YPAA 1A0AA 4ATHA 4ATIA 1AM9A 2LFHA 1UKLC 4H10B 1NLWA 2MH3A 1MDYA 1NKPB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MUJ A;  2QL2 B;  4H10 A;  1NKP A;  5I50 A;  2YPB B;  2QL2 A;  4ATK A;  4AYA A;  4F3L B;  3U5V A;  2YPB A;  1AN4 A;  1AN2 A;  4F3L A;  2YPA B;  1HLO A;  5I4Z A;  1NLW B;  5EYO A;  1MDY B;  1R05 A;  2YPA A;  1A0A A;  4ATH A;  4ATI A;  1AM9 A;  2LFH A;  1UKL C;  4H10 B;  1NLW A;  2MH3 A;  1MDY A;  1NKP B; 
#chains in the Genus database with same CATH topology
 3MUJ A;  2QL2 B;  4H10 A;  1NKP A;  5I50 A;  2YPB B;  1K1F A;  2QL2 A;  4ATK A;  4AYA A;  4F3L B;  1ZZA A;  3U5V A;  2YPB A;  1AN4 A;  1AN2 A;  4F3L A;  2YPA B;  1HLO A;  5I4Z A;  1NLW B;  5EYO A;  1MDY B;  1R05 A;  2YPA A;  1A0A A;  4ATH A;  4ATI A;  1AM9 A;  2LFH A;  1UKL C;  4H10 B;  1NLW A;  2MH3 A;  1MDY A;  1NKP B; 
#chains in the Genus database with same CATH homology
 3MUJ A;  2QL2 B;  4H10 A;  1NKP A;  5I50 A;  2YPB B;  2QL2 A;  4ATK A;  4AYA A;  4F3L B;  3U5V A;  2YPB A;  1AN4 A;  1AN2 A;  4F3L A;  2YPA B;  1HLO A;  5I4Z A;  1NLW B;  5EYO A;  1MDY B;  1R05 A;  2YPA A;  1A0A A;  4ATH A;  4ATI A;  1AM9 A;  2LFH A;  1UKL C;  4H10 B;  1NLW A;  2MH3 A;  1MDY A;  1NKP B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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