2A5MA

Nmr structure of murine gamma-s crystallin from joint refinement with saxs data
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
177
structure length
177
Chain Sequence
SKTGGKISFYEDRNFQGRRYDCDCDCADFRSYLSRCNSIRVEGGTWAVYERPNFSGHMYILPQGEYPEYQRWMGLNDRLGSCRAVHLSSGGQAKIQVFEKGDFNGQMYETTEDCPSIMEQFHLREIHSCKVVEGTWIFYELPNYRGRQYLLDKKEYRKPVDWGAASPAIQSFRRIVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Refinement of Multidomain Protein Structures by Combination of Solution Small-Angle X-ray Scattering and NMR Data.
pubmed doi rcsb
molecule tags Structural protein
source organism Mus musculus
molecule keywords Gamma crystallin S
total genus 21
structure length 177
sequence length 177
ec nomenclature
pdb deposition date 2005-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00030 Crystall Beta/Gamma crystallin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.20.10 Mainly Beta Sandwich Gamma-B Crystallin; domain 1 Crystallins 2a5mA02
2.60.20.10 Mainly Beta Sandwich Gamma-B Crystallin; domain 1 Crystallins 2a5mA01
4W9BA 3IAJA 4EL6A 1H4AX 2BV2A 3I9HA 3SO1A 1ZIRA 4W9AA 1I5IA 1A45A 3LWKA 3ENTA 4GR7A 3SO0A 4FD9A 1YHPA 1BLBA 3HZ2A 1HA4A 4GCRA 1AG4A 3ENUA 3HZBA 5HT9A 3SNYA 1HK0X 1BD7A 2K1XA 1ELPA 2BB2A 2V2UA 4PSPA 1ZWMA 4IAUA 4AKAA 2JDFA 2K1WA 2B1OA 2KFBA 1A7HA 1ZIEA 1PRSA 1PRRA 4PSRA 1ZGTA 2G98A 2M3CA 1GCSA 2NBRA 2M3UA 1YTQA 4JGFA 1AMMA 1A5DA 3SNZA 2A5MA 1E7NA 1HDFA 2KP5A 5HT8A 1GAMA 1DSLA 1ZIQA 2DADA 2JDGA 1M8UA 3QK3A 1OKIA 4NI3A 2M3TA 1NPSA 3CW3A 1ZWOA
chains in the Genus database with same CATH superfamily
4W9BA 3IAJA 1GH5A 1ZIRA 1A45A 3ENTA 3HZ2A 1AG4A 3SNYA 2K1XA 1ELPA 4PSPA 3UJZA 4AKAA 2K1WA 2B1OA 1PRSA 1GCSA 2A5MA 2KP5A 2DADA 1M8UA 2M3TA 2M3UA 1BHUA 3LWKA 1YHPA 1BD7A 2V2UA 4IAUA 1ZGTA 2G98A 1A5DA 3QK3A 1OKIA 1ZWOA 3SO1A 3I9HA 1I5IA 4GR7A 3SO0A 1HA4A 3ENUA 2BB2A 2KFBA 1A7HA 1ZIEA 4PSRA 2M3CA 2NBRA 1YTQA 3SNZA 1E7NA 1GAMA 2JDGA 1NPSA 4EL6A 1H4AX 1WKTA 2BV2A 4W9AA 1C01A 1F53A 4FD9A 1BLBA 1G6EA 4GCRA 3HZBA 5HT9A 1HK0X 1ZWMA 2JDFA 1PRRA 4JGFA 1AMMA 1HDFA 5HT8A 1DSLA 1ZIQA 4NI3A 3CW3A
chains in the Genus database with same CATH topology
4W9BA 3IAJA 4EL6A 1H4AX 2BV2A 3I9HA 3SO1A 1ZIRA 4W9AA 1I5IA 1A45A 3LWKA 3ENTA 4GR7A 3SO0A 4FD9A 1YHPA 1BLBA 3HZ2A 1HA4A 4GCRA 1AG4A 3ENUA 3HZBA 5HT9A 3SNYA 1HK0X 1BD7A 2K1XA 1ELPA 2BB2A 2V2UA 4PSPA 1ZWMA 4IAUA 4AKAA 2JDFA 2K1WA 2B1OA 2KFBA 1A7HA 1ZIEA 1PRSA 1PRRA 4PSRA 1ZGTA 2G98A 2M3CA 1GCSA 2NBRA 2M3UA 1YTQA 4JGFA 1AMMA 1A5DA 3SNZA 2A5MA 1E7NA 1HDFA 2KP5A 5HT8A 1GAMA 1DSLA 1ZIQA 2DADA 2JDGA 1M8UA 3QK3A 1OKIA 4NI3A 2M3TA 1NPSA 3CW3A 1ZWOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4W9B A;  3IAJ A;  4EL6 A;  1H4A X;  2BV2 A;  3I9H A;  3SO1 A;  1ZIR A;  4W9A A;  1I5I A;  1A45 A;  3LWK A;  3ENT A;  4GR7 A;  3SO0 A;  4FD9 A;  1YHP A;  1BLB A;  3HZ2 A;  1HA4 A;  4GCR A;  1AG4 A;  3ENU A;  3HZB A;  5HT9 A;  3SNY A;  1HK0 X;  1BD7 A;  2K1X A;  1ELP A;  2BB2 A;  2V2U A;  4PSP A;  1ZWM A;  4IAU A;  4AKA A;  2JDF A;  2K1W A;  2B1O A;  2KFB A;  1A7H A;  1ZIE A;  1PRS A;  1PRR A;  4PSR A;  1ZGT A;  2G98 A;  2M3C A;  1GCS A;  2NBR A;  2M3U A;  1YTQ A;  4JGF A;  1AMM A;  1A5D A;  3SNZ A;  2A5M A;  1E7N A;  1HDF A;  2KP5 A;  5HT8 A;  1GAM A;  1DSL A;  1ZIQ A;  2DAD A;  2JDG A;  1M8U A;  3QK3 A;  1OKI A;  4NI3 A;  2M3T A;  1NPS A;  3CW3 A;  1ZWO A; 
#chains in the Genus database with same CATH topology
 4W9B A;  3IAJ A;  1GH5 A;  1ZIR A;  1A45 A;  3ENT A;  3HZ2 A;  1AG4 A;  3SNY A;  2K1X A;  1ELP A;  4PSP A;  3UJZ A;  4AKA A;  2K1W A;  2B1O A;  1PRS A;  1GCS A;  2A5M A;  2KP5 A;  2DAD A;  1M8U A;  2M3T A;  2M3U A;  1BHU A;  3LWK A;  1YHP A;  1BD7 A;  2V2U A;  4IAU A;  1ZGT A;  2G98 A;  1A5D A;  3QK3 A;  1OKI A;  1ZWO A;  3SO1 A;  3I9H A;  1I5I A;  4GR7 A;  3SO0 A;  1HA4 A;  3ENU A;  2BB2 A;  2KFB A;  1A7H A;  1ZIE A;  4PSR A;  2M3C A;  2NBR A;  1YTQ A;  3SNZ A;  1E7N A;  1GAM A;  2JDG A;  1NPS A;  4EL6 A;  1H4A X;  1WKT A;  2BV2 A;  4W9A A;  1C01 A;  1F53 A;  4FD9 A;  1BLB A;  1G6E A;  4GCR A;  3HZB A;  5HT9 A;  1HK0 X;  1ZWM A;  2JDF A;  1PRR A;  4JGF A;  1AMM A;  1HDF A;  5HT8 A;  1DSL A;  1ZIQ A;  4NI3 A;  3CW3 A; 
#chains in the Genus database with same CATH homology
 4W9B A;  3IAJ A;  4EL6 A;  1H4A X;  2BV2 A;  3I9H A;  3SO1 A;  1ZIR A;  4W9A A;  1I5I A;  1A45 A;  3LWK A;  3ENT A;  4GR7 A;  3SO0 A;  4FD9 A;  1YHP A;  1BLB A;  3HZ2 A;  1HA4 A;  4GCR A;  1AG4 A;  3ENU A;  3HZB A;  5HT9 A;  3SNY A;  1HK0 X;  1BD7 A;  2K1X A;  1ELP A;  2BB2 A;  2V2U A;  4PSP A;  1ZWM A;  4IAU A;  4AKA A;  2JDF A;  2K1W A;  2B1O A;  2KFB A;  1A7H A;  1ZIE A;  1PRS A;  1PRR A;  4PSR A;  1ZGT A;  2G98 A;  2M3C A;  1GCS A;  2NBR A;  2M3U A;  1YTQ A;  4JGF A;  1AMM A;  1A5D A;  3SNZ A;  2A5M A;  1E7N A;  1HDF A;  2KP5 A;  5HT8 A;  1GAM A;  1DSL A;  1ZIQ A;  2DAD A;  2JDG A;  1M8U A;  3QK3 A;  1OKI A;  4NI3 A;  2M3T A;  1NPS A;  3CW3 A;  1ZWO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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