2EB4A

Crystal structure of apo-hpcg
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
267
structure length
261
Chain Sequence
MFDKHTHTLIAQRLDQAEKQREQIRAISLDYPEITIEDAYAVQREWVRLKIAEGRTLKGHKIGLTSKAMQASSQISEPDYGALLDDMFFHDGSDIPTDRFIVPRIEVELAFVLAKPLRGPNCTLFDVYNATDYVIPALELIDARCHNIPRKVFDTISDNAANAGVILGGRPIKPDELDLRWISALMYRNGVIEETGVAAGVLNHPANGVAWLANKLAPYDVQLEAGQIILGGSFTRPVPARKGDTFHVDYGNMGSISCRFV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and Mechanism of HpcG, a Hydratase in the Homoprotocatechuate Degradation Pathway of Escherichia coli
pubmed doi rcsb
molecule keywords 2-oxo-hept-3-ene-1,7-dioate hydratase
molecule tags Lyase
source organism Escherichia coli
total genus 81
structure length 261
sequence length 267
chains with identical sequence B, C, D, E
ec nomenclature ec 4.2.1.-:
pdb deposition date 2007-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01557 FAA_hydrolase Fumarylacetoacetate (FAA) hydrolase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.850.10 Alpha Beta Alpha-Beta Complex Fumarylacetoacetate hydrolase; domain 2 Fumarylacetoacetase-like, C-terminal domain 2eb4A00
3R6OA 1QCOA 4MAQA 4PFZA 2DFUA 1HYOA 5D2KA 5D2HA 3LZKA 3RR6A 5D2JA 4DBFA 2Q1CX 3BQBA 5D2GA 2Q1AX 2EB6A 4QKUA 5D2FA 2EB5A 1SV6A 1SAWA 1QQJA 1WZOA 1I7OA 1NKQA 2EB4A 1QCNA 3QDFA 2Q19X 3V77A 2Q18X 2WQTA 1NR9A 3S52A 2HZYA 4DBHA 1GTTA 2Q1DX 5D2IA
chains in the Genus database with same CATH superfamily
3R6OA 1QCOA 4MAQA 4PFZA 2DFUA 1HYOA 5D2KA 5D2HA 3LZKA 3RR6A 5D2JA 4DBFA 2Q1CX 3BQBA 5D2GA 2Q1AX 2EB6A 4QKUA 5D2FA 2EB5A 1SV6A 1SAWA 1QQJA 1WZOA 1I7OA 1NKQA 2EB4A 1QCNA 3QDFA 2Q19X 3V77A 2Q18X 2WQTA 1NR9A 3S52A 2HZYA 4DBHA 1GTTA 2Q1DX 5D2IA
chains in the Genus database with same CATH topology
3R6OA 1QCOA 4MAQA 4PFZA 2DFUA 1HYOA 5D2KA 5D2HA 3LZKA 3RR6A 5D2JA 4DBFA 2Q1CX 3BQBA 5D2GA 2Q1AX 2EB6A 4QKUA 5D2FA 2EB5A 1SV6A 1SAWA 1QQJA 1WZOA 1I7OA 1NKQA 2EB4A 1QCNA 3QDFA 2Q19X 3V77A 2Q18X 2WQTA 1NR9A 3S52A 2HZYA 4DBHA 1GTTA 2Q1DX 5D2IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3R6O A;  1QCO A;  4MAQ A;  4PFZ A;  2DFU A;  1HYO A;  5D2K A;  5D2H A;  3LZK A;  3RR6 A;  5D2J A;  4DBF A;  2Q1C X;  3BQB A;  5D2G A;  2Q1A X;  2EB6 A;  4QKU A;  5D2F A;  2EB5 A;  1SV6 A;  1SAW A;  1QQJ A;  1WZO A;  1I7O A;  1NKQ A;  2EB4 A;  1QCN A;  3QDF A;  2Q19 X;  3V77 A;  2Q18 X;  2WQT A;  1NR9 A;  3S52 A;  2HZY A;  4DBH A;  1GTT A;  2Q1D X;  5D2I A; 
#chains in the Genus database with same CATH topology
 3R6O A;  1QCO A;  4MAQ A;  4PFZ A;  2DFU A;  1HYO A;  5D2K A;  5D2H A;  3LZK A;  3RR6 A;  5D2J A;  4DBF A;  2Q1C X;  3BQB A;  5D2G A;  2Q1A X;  2EB6 A;  4QKU A;  5D2F A;  2EB5 A;  1SV6 A;  1SAW A;  1QQJ A;  1WZO A;  1I7O A;  1NKQ A;  2EB4 A;  1QCN A;  3QDF A;  2Q19 X;  3V77 A;  2Q18 X;  2WQT A;  1NR9 A;  3S52 A;  2HZY A;  4DBH A;  1GTT A;  2Q1D X;  5D2I A; 
#chains in the Genus database with same CATH homology
 3R6O A;  1QCO A;  4MAQ A;  4PFZ A;  2DFU A;  1HYO A;  5D2K A;  5D2H A;  3LZK A;  3RR6 A;  5D2J A;  4DBF A;  2Q1C X;  3BQB A;  5D2G A;  2Q1A X;  2EB6 A;  4QKU A;  5D2F A;  2EB5 A;  1SV6 A;  1SAW A;  1QQJ A;  1WZO A;  1I7O A;  1NKQ A;  2EB4 A;  1QCN A;  3QDF A;  2Q19 X;  3V77 A;  2Q18 X;  2WQT A;  1NR9 A;  3S52 A;  2HZY A;  4DBH A;  1GTT A;  2Q1D X;  5D2I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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