2EB4 | Genus

Total Genus 81

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	81
sequence length	267
structure length	261
Chain Sequence	MFDKHTHTLIAQRLDQAEKQREQIRAISLDYPEITIEDAYAVQREWVRLKIAEGRTLKGHKIGLTSKAMQASSQISEPDYGALLDDMFFHDGSDIPTDRFIVPRIEVELAFVLAKPLRGPNCTLFDVYNATDYVIPALELIDARCHNIPRKVFDTISDNAANAGVILGGRPIKPDELDLRWISALMYRNGVIEETGVAAGVLNHPANGVAWLANKLAPYDVQLEAGQIILGGSFTRPVPARKGDTFHVDYGNMGSISCRFV

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Lyase
source organism	Escherichia coli
publication title	Structure and Mechanism of HpcG, a Hydratase in the Homoprotocatechuate Degradation Pathway of Escherichia coli pubmed doi rcsb
molecule keywords	2-oxo-hept-3-ene-1,7-dioate hydratase
total genus	81
structure length	261
sequence length	267
chains with identical sequence	B, C, D, E
ec nomenclature	ec 4.2.1.-:
pdb deposition date	2007-02-07

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01557	FAA_hydrolase	Fumarylacetoacetate (FAA) hydrolase family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.850.10	Alpha Beta	Alpha-Beta Complex	Fumarylacetoacetate hydrolase; domain 2	Fumarylacetoacetase-like, C-terminal domain	2eb4A00

5D2FA 2EB6A 3BQBA 4PFZA 1NKQA 2EB5A 1SV6A 1SAWA 2HZYA 5D2JA 3RR6A 3R6OA 5D2KA 1QCNA 2WQTA 4DBFA 4MAQA 2Q1CX 3QDFA 4QKUA 1NR9A 1QQJA 5D2GA 2EB4A 5D2IA 4DBHA 1WZOA 1QCOA 2Q19X 3LZKA 2DFUA 3V77A 3S52A 2Q1DX 1GTTA 1HYOA 5D2HA 2Q1AX 2Q18X 1I7OA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 5D2F A;  2EB6 A;  3BQB A;  4PFZ A;  1NKQ A;  2EB5 A;  1SV6 A;  1SAW A;  2HZY A;  5D2J A;  3RR6 A;  3R6O A;  5D2K A;  1QCN A;  2WQT A;  4DBF A;  4MAQ A;  2Q1C X;  3QDF A;  4QKU A;  1NR9 A;  1QQJ A;  5D2G A;  2EB4 A;  5D2I A;  4DBH A;  1WZO A;  1QCO A;  2Q19 X;  3LZK A;  2DFU A;  3V77 A;  3S52 A;  2Q1D X;  1GTT A;  1HYO A;  5D2H A;  2Q1A X;  2Q18 X;  1I7O A; 
#chains in the Genus database with same CATH topology
 5D2F A;  2EB6 A;  3BQB A;  4PFZ A;  1NKQ A;  2EB5 A;  1SV6 A;  1SAW A;  2HZY A;  5D2J A;  3RR6 A;  3R6O A;  5D2K A;  1QCN A;  2WQT A;  4DBF A;  4MAQ A;  2Q1C X;  3QDF A;  4QKU A;  1NR9 A;  1QQJ A;  5D2G A;  2EB4 A;  5D2I A;  4DBH A;  1WZO A;  1QCO A;  2Q19 X;  3LZK A;  2DFU A;  3V77 A;  3S52 A;  2Q1D X;  1GTT A;  1HYO A;  5D2H A;  2Q1A X;  2Q18 X;  1I7O A; 
#chains in the Genus database with same CATH homology
 5D2F A;  2EB6 A;  3BQB A;  4PFZ A;  1NKQ A;  2EB5 A;  1SV6 A;  1SAW A;  2HZY A;  5D2J A;  3RR6 A;  3R6O A;  5D2K A;  1QCN A;  2WQT A;  4DBF A;  4MAQ A;  2Q1C X;  3QDF A;  4QKU A;  1NR9 A;  1QQJ A;  5D2G A;  2EB4 A;  5D2I A;  4DBH A;  1WZO A;  1QCO A;  2Q19 X;  3LZK A;  2DFU A;  3V77 A;  3S52 A;  2Q1D X;  1GTT A;  1HYO A;  5D2H A;  2Q1A X;  2Q18 X;  1I7O A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2EB4A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations