2EB4 | Genus

Total Genus 81

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	81
sequence length	267
structure length	261
Chain Sequence	MFDKHTHTLIAQRLDQAEKQREQIRAISLDYPEITIEDAYAVQREWVRLKIAEGRTLKGHKIGLTSKAMQASSQISEPDYGALLDDMFFHDGSDIPTDRFIVPRIEVELAFVLAKPLRGPNCTLFDVYNATDYVIPALELIDARCHNIPRKVFDTISDNAANAGVILGGRPIKPDELDLRWISALMYRNGVIEETGVAAGVLNHPANGVAWLANKLAPYDVQLEAGQIILGGSFTRPVPARKGDTFHVDYGNMGSISCRFV

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Structure and Mechanism of HpcG, a Hydratase in the Homoprotocatechuate Degradation Pathway of Escherichia coli pubmed doi rcsb
molecule keywords	2-oxo-hept-3-ene-1,7-dioate hydratase
molecule tags	Lyase
source organism	Escherichia coli
total genus	81
structure length	261
sequence length	267
chains with identical sequence	B, C, D, E
ec nomenclature	ec 4.2.1.-:
pdb deposition date	2007-02-07

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01557	FAA_hydrolase	Fumarylacetoacetate (FAA) hydrolase family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.850.10	Alpha Beta	Alpha-Beta Complex	Fumarylacetoacetate hydrolase; domain 2	Fumarylacetoacetase-like, C-terminal domain	2eb4A00

5D2JA 2Q1AX 1QQJA 3RR6A 2EB4A 1NR9A 2Q1CX 2Q1DX 1HYOA 4DBFA 1SV6A 1GTTA 2EB5A 1WZOA 3LZKA 5D2HA 3R6OA 4QKUA 5D2GA 3V77A 1I7OA 2Q18X 2DFUA 1NKQA 5D2IA 3BQBA 3QDFA 5D2KA 4DBHA 1QCOA 3S52A 4PFZA 1QCNA 2HZYA 5D2FA 2EB6A 2WQTA 4MAQA 1SAWA 2Q19X
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 5D2J A;  2Q1A X;  1QQJ A;  3RR6 A;  2EB4 A;  1NR9 A;  2Q1C X;  2Q1D X;  1HYO A;  4DBF A;  1SV6 A;  1GTT A;  2EB5 A;  1WZO A;  3LZK A;  5D2H A;  3R6O A;  4QKU A;  5D2G A;  3V77 A;  1I7O A;  2Q18 X;  2DFU A;  1NKQ A;  5D2I A;  3BQB A;  3QDF A;  5D2K A;  4DBH A;  1QCO A;  3S52 A;  4PFZ A;  1QCN A;  2HZY A;  5D2F A;  2EB6 A;  2WQT A;  4MAQ A;  1SAW A;  2Q19 X; 
#chains in the Genus database with same CATH topology
 5D2J A;  2Q1A X;  1QQJ A;  3RR6 A;  2EB4 A;  1NR9 A;  2Q1C X;  2Q1D X;  1HYO A;  4DBF A;  1SV6 A;  1GTT A;  2EB5 A;  1WZO A;  3LZK A;  5D2H A;  3R6O A;  4QKU A;  5D2G A;  3V77 A;  1I7O A;  2Q18 X;  2DFU A;  1NKQ A;  5D2I A;  3BQB A;  3QDF A;  5D2K A;  4DBH A;  1QCO A;  3S52 A;  4PFZ A;  1QCN A;  2HZY A;  5D2F A;  2EB6 A;  2WQT A;  4MAQ A;  1SAW A;  2Q19 X; 
#chains in the Genus database with same CATH homology
 5D2J A;  2Q1A X;  1QQJ A;  3RR6 A;  2EB4 A;  1NR9 A;  2Q1C X;  2Q1D X;  1HYO A;  4DBF A;  1SV6 A;  1GTT A;  2EB5 A;  1WZO A;  3LZK A;  5D2H A;  3R6O A;  4QKU A;  5D2G A;  3V77 A;  1I7O A;  2Q18 X;  2DFU A;  1NKQ A;  5D2I A;  3BQB A;  3QDF A;  5D2K A;  4DBH A;  1QCO A;  3S52 A;  4PFZ A;  1QCN A;  2HZY A;  5D2F A;  2EB6 A;  2WQT A;  4MAQ A;  1SAW A;  2Q19 X;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2EB4A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations