2Q1CX

2-keto-3-deoxy-d-arabinonate dehydratase complexed with calcium and 2-oxobutyrate
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
291
structure length
291
Chain Sequence
MKLFRVVKRGYYISYAILDNSTIIRLDEDPIKALMRYSENKEVLGDRVTGIDYQSLLKSFQINDIRITKPIDPPEVWGSGISYEMARERYSEENVAKILGKTIYEKVYDAVRPEIFFKATPNRCVGHGEAIAVRSDSEWTLPEPELAVVLDSNGKILGYTIMDDVSARDLEAENPLYLPQSKIYAGCCAFGPVIVTSDEIKNPYSLDITLKIVREGRVFFEGSVNTNKMRRKIEEQIQYLIRDNPIPDGTILTTGTAIVPGRDKGLKDEDIVEITISNIGTLITPVKKRRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
pubmed doi rcsb
source organism Sulfolobus solfataricus
molecule tags Lyase
molecule keywords 2-keto-3-deoxy-D-arabinonate dehydratase
total genus 74
structure length 291
sequence length 291
ec nomenclature ec 4.2.1.141: 2-dehydro-3-deoxy-D-arabinonate dehydratase.
pdb deposition date 2007-05-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01557 FAA_hydrolase Fumarylacetoacetate (FAA) hydrolase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.330.40 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 2q1cX01
3.90.850.10 Alpha Beta Alpha-Beta Complex Fumarylacetoacetate hydrolase; domain 2 Fumarylacetoacetase-like, C-terminal domain 2q1cX02
3LZKA 1QQJA 2EB6A 2Q1DX 1QCNA 3BQBA 5D2IA 1HYOA 1SV6A 1NR9A 2Q1AX 5D2JA 4DBHA 2Q19X 1SAWA 2WQTA 1QCOA 5D2KA 3RR6A 1I7OA 3R6OA 4PFZA 5D2FA 4DBFA 1NKQA 5D2GA 2Q18X 2Q1CX 2EB4A 2DFUA 2HZYA 5D2HA 4MAQA 1GTTA 1WZOA 3QDFA 4QKUA 3S52A 3V77A 2EB5A
chains in the Genus database with same CATH superfamily
2MM2A 4UC4A 3LHDA 3BQBA 4AS1A 1NR9A 1QCSA 3QQ7A 2YVLA 4AQ7A 5CCXA 3TIWA 1QCOA 4ARIA 5D6YA 3RR6A 5FTMA 4FIBA 2LW6A 2YUJA 3R6OA 5D2FA 1QDNA 1NKQA 3MB5A 4KO8A 2HZYA 3ZGZA 3V77A 5C18A 2KY9A 3LZKA 1QQJA 2EB6A 2Q1DX 1QCNA 4KDIA 3HU1A 5EPPA 1CZ4A 5FTJA 3QC8A 1SAWA 4KODA 5D2KA 1WLFA 5D6WA 4DBFA 3CF2A 2Q18X 4ARCA 1I9GA 5FTKA 5D6XA 1WZOA 2EB5A 5DYIA 1S3SA 3ZJUA 5ERGB 3ZJVA 2PJHB 3FPTA 1SV6A 2Q1AX 2B25A 4DBHA 2Q19X 4KDLA 2WQTA 2GF7A 5DYGA 2GFAA 1I7OA 4PFZA 3QWZA 5C1BA 5D2GA 2EB4A 2DFUA 5D2HA 4MAQA 1GTTA 3QDFA 3S52A 2MM0A 3QQ8A 5EQJB 4CQNA 1CZ5A 5D2IA 1R7RA 3LGAA 1HYOA 2QQSA 5CD1A 1O54A 5B6CA 3ZJTA 5D2JA 2JV2A 1CR5A 2QQRA 3FPRA 1E32A 1ZC1A 5FTLA 4RV0A 5GLFA 5CCBA 2XDPA 3FPUA 2Q1CX 5FTNA 4QKUA 4KLNA 2PWYA 3HU2A 3HU3A
chains in the Genus database with same CATH topology
2MM2A 4UC4A 3LHDA 3BQBA 4AS1A 1NR9A 1QCSA 3QQ7A 2YVLA 4AQ7A 5CCXA 3TIWA 1QCOA 4ARIA 5D6YA 3RR6A 5FTMA 4FIBA 2LW6A 2YUJA 3R6OA 5D2FA 1QDNA 1NKQA 3MB5A 4KO8A 2HZYA 3ZGZA 3V77A 5C18A 2KY9A 3LZKA 1QQJA 2EB6A 2Q1DX 1QCNA 4KDIA 3HU1A 5EPPA 1CZ4A 5FTJA 3QC8A 1SAWA 4KODA 5D2KA 1WLFA 5D6WA 4DBFA 3CF2A 2Q18X 4ARCA 1I9GA 5FTKA 5D6XA 1WZOA 2EB5A 5DYIA 1S3SA 3ZJUA 5ERGB 3ZJVA 2PJHB 3FPTA 1SV6A 2Q1AX 2B25A 4DBHA 2Q19X 4KDLA 2WQTA 2GF7A 5DYGA 2GFAA 1I7OA 4PFZA 3QWZA 5C1BA 5D2GA 2EB4A 2DFUA 5D2HA 4MAQA 1GTTA 3QDFA 3S52A 2MM0A 3QQ8A 5EQJB 4CQNA 1CZ5A 5D2IA 1R7RA 3LGAA 1HYOA 2QQSA 5CD1A 1O54A 5B6CA 3ZJTA 5D2JA 2JV2A 1CR5A 2QQRA 3FPRA 1E32A 1ZC1A 5FTLA 4RV0A 5GLFA 5CCBA 2XDPA 3FPUA 2Q1CX 5FTNA 4QKUA 4KLNA 2PWYA 3HU2A 3HU3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LZK A;  1QQJ A;  2EB6 A;  2Q1D X;  1QCN A;  3BQB A;  5D2I A;  1HYO A;  1SV6 A;  1NR9 A;  2Q1A X;  5D2J A;  4DBH A;  2Q19 X;  1SAW A;  2WQT A;  1QCO A;  5D2K A;  3RR6 A;  1I7O A;  3R6O A;  4PFZ A;  5D2F A;  4DBF A;  1NKQ A;  5D2G A;  2Q18 X;  2Q1C X;  2EB4 A;  2DFU A;  2HZY A;  5D2H A;  4MAQ A;  1GTT A;  1WZO A;  3QDF A;  4QKU A;  3S52 A;  3V77 A;  2EB5 A; 
#chains in the Genus database with same CATH topology
 2MM2 A;  4UC4 A;  3LHD A;  3BQB A;  4AS1 A;  1NR9 A;  1QCS A;  3QQ7 A;  2YVL A;  4AQ7 A;  5CCX A;  3TIW A;  1QCO A;  4ARI A;  5D6Y A;  3RR6 A;  5FTM A;  4FIB A;  2LW6 A;  2YUJ A;  3R6O A;  5D2F A;  1QDN A;  1NKQ A;  3MB5 A;  4KO8 A;  2HZY A;  3ZGZ A;  3V77 A;  5C18 A;  2KY9 A;  3LZK A;  1QQJ A;  2EB6 A;  2Q1D X;  1QCN A;  4KDI A;  3HU1 A;  5EPP A;  1CZ4 A;  5FTJ A;  3QC8 A;  1SAW A;  4KOD A;  5D2K A;  1WLF A;  5D6W A;  4DBF A;  3CF2 A;  2Q18 X;  4ARC A;  1I9G A;  5FTK A;  5D6X A;  1WZO A;  2EB5 A;  5DYI A;  1S3S A;  3ZJU A;  5ERG B;  3ZJV A;  2PJH B;  3FPT A;  1SV6 A;  2Q1A X;  2B25 A;  4DBH A;  2Q19 X;  4KDL A;  2WQT A;  2GF7 A;  5DYG A;  2GFA A;  1I7O A;  4PFZ A;  3QWZ A;  5C1B A;  5D2G A;  2EB4 A;  2DFU A;  5D2H A;  4MAQ A;  1GTT A;  3QDF A;  3S52 A;  2MM0 A;  3QQ8 A;  5EQJ B;  4CQN A;  1CZ5 A;  5D2I A;  1R7R A;  3LGA A;  1HYO A;  2QQS A;  5CD1 A;  1O54 A;  5B6C A;  3ZJT A;  5D2J A;  2JV2 A;  1CR5 A;  2QQR A;  3FPR A;  1E32 A;  1ZC1 A;  5FTL A;  4RV0 A;  5GLF A;  5CCB A;  2XDP A;  3FPU A;  2Q1C X;  5FTN A;  4QKU A;  4KLN A;  2PWY A;  3HU2 A;  3HU3 A; 
#chains in the Genus database with same CATH homology
 2MM2 A;  4UC4 A;  3LHD A;  3BQB A;  4AS1 A;  1NR9 A;  1QCS A;  3QQ7 A;  2YVL A;  4AQ7 A;  5CCX A;  3TIW A;  1QCO A;  4ARI A;  5D6Y A;  3RR6 A;  5FTM A;  4FIB A;  2LW6 A;  2YUJ A;  3R6O A;  5D2F A;  1QDN A;  1NKQ A;  3MB5 A;  4KO8 A;  2HZY A;  3ZGZ A;  3V77 A;  5C18 A;  2KY9 A;  3LZK A;  1QQJ A;  2EB6 A;  2Q1D X;  1QCN A;  4KDI A;  3HU1 A;  5EPP A;  1CZ4 A;  5FTJ A;  3QC8 A;  1SAW A;  4KOD A;  5D2K A;  1WLF A;  5D6W A;  4DBF A;  3CF2 A;  2Q18 X;  4ARC A;  1I9G A;  5FTK A;  5D6X A;  1WZO A;  2EB5 A;  5DYI A;  1S3S A;  3ZJU A;  5ERG B;  3ZJV A;  2PJH B;  3FPT A;  1SV6 A;  2Q1A X;  2B25 A;  4DBH A;  2Q19 X;  4KDL A;  2WQT A;  2GF7 A;  5DYG A;  2GFA A;  1I7O A;  4PFZ A;  3QWZ A;  5C1B A;  5D2G A;  2EB4 A;  2DFU A;  5D2H A;  4MAQ A;  1GTT A;  3QDF A;  3S52 A;  2MM0 A;  3QQ8 A;  5EQJ B;  4CQN A;  1CZ5 A;  5D2I A;  1R7R A;  3LGA A;  1HYO A;  2QQS A;  5CD1 A;  1O54 A;  5B6C A;  3ZJT A;  5D2J A;  2JV2 A;  1CR5 A;  2QQR A;  3FPR A;  1E32 A;  1ZC1 A;  5FTL A;  4RV0 A;  5GLF A;  5CCB A;  2XDP A;  3FPU A;  2Q1C X;  5FTN A;  4QKU A;  4KLN A;  2PWY A;  3HU2 A;  3HU3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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