2Q1CX

2-keto-3-deoxy-d-arabinonate dehydratase complexed with calcium and 2-oxobutyrate
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
291
structure length
291
Chain Sequence
MKLFRVVKRGYYISYAILDNSTIIRLDEDPIKALMRYSENKEVLGDRVTGIDYQSLLKSFQINDIRITKPIDPPEVWGSGISYEMARERYSEENVAKILGKTIYEKVYDAVRPEIFFKATPNRCVGHGEAIAVRSDSEWTLPEPELAVVLDSNGKILGYTIMDDVSARDLEAENPLYLPQSKIYAGCCAFGPVIVTSDEIKNPYSLDITLKIVREGRVFFEGSVNTNKMRRKIEEQIQYLIRDNPIPDGTILTTGTAIVPGRDKGLKDEDIVEITISNIGTLITPVKKRRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 2-keto-3-deoxy-D-arabinonate dehydratase
publication title Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
pubmed doi rcsb
source organism Sulfolobus solfataricus
molecule tags Lyase
total genus 74
structure length 291
sequence length 291
ec nomenclature ec 4.2.1.141: 2-dehydro-3-deoxy-D-arabinonate dehydratase.
pdb deposition date 2007-05-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01557 FAA_hydrolase Fumarylacetoacetate (FAA) hydrolase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.330.40 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 2q1cX01
3.90.850.10 Alpha Beta Alpha-Beta Complex Fumarylacetoacetate hydrolase; domain 2 Fumarylacetoacetase-like, C-terminal domain 2q1cX02
3QDFA 4DBHA 3R6OA 3S52A 2EB6A 5D2IA 2Q19X 2DFUA 1SAWA 3RR6A 1WZOA 2Q1CX 5D2HA 2Q18X 2Q1DX 2Q1AX 3BQBA 2EB4A 1QCNA 1QQJA 1I7OA 5D2FA 4MAQA 5D2KA 1SV6A 4PFZA 1HYOA 4QKUA 2WQTA 3LZKA 4DBFA 1QCOA 1NR9A 5D2JA 3V77A 1NKQA 2EB5A 1GTTA 2HZYA 5D2GA
chains in the Genus database with same CATH superfamily
2QQRA 3QDFA 4ARIA 3R6OA 2PJHB 3S52A 2B25A 3RR6A 5CCXA 3BQBA 3LHDA 5C1BA 1QCNA 3QWZA 5D6YA 4ARCA 2YUJA 4KDIA 5EQJB 5D2KA 2MM2A 4KDLA 4PFZA 1CZ5A 1HYOA 5GLFA 3HU1A 4AS1A 3V77A 3HU3A 2EB5A 5CCBA 2QQSA 3TIWA 4DBHA 5D6XA 2GF7A 4UC4A 3QQ7A 2PWYA 2DFUA 3FPTA 1SAWA 1WZOA 1CR5A 1I9GA 2Q1CX 5D2HA 3ZGZA 1S3SA 1QQJA 1I7OA 2MM0A 5CD1A 5FTLA 5B6CA 4KODA 1NR9A 1NKQA 1QDNA 5D2GA 1WLFA 1O54A 1R7RA 3ZJVA 2EB6A 2LW6A 5D2IA 2XDPA 4AQ7A 2Q18X 2Q1AX 3MB5A 2EB4A 3CF2A 1E32A 3ZJTA 5EPPA 5DYIA 3QC8A 3LZKA 4DBFA 5C18A 1ZC1A 2HZYA 2KY9A 5FTNA 5FTJA 2YVLA 1QCSA 5DYGA 3HU2A 4KO8A 4CQNA 4RV0A 2Q19X 1CZ4A 2GFAA 5FTMA 3ZJUA 2Q1DX 5ERGB 4FIBA 4KLNA 3QQ8A 3LGAA 5D2FA 5D6WA 4MAQA 1SV6A 4QKUA 2WQTA 2JV2A 5FTKA 1QCOA 5D2JA 3FPRA 3FPUA 1GTTA
chains in the Genus database with same CATH topology
2QQRA 3QDFA 4ARIA 3R6OA 2PJHB 3S52A 2B25A 3RR6A 5CCXA 3BQBA 3LHDA 5C1BA 1QCNA 3QWZA 5D6YA 4ARCA 2YUJA 4KDIA 5EQJB 5D2KA 2MM2A 4KDLA 4PFZA 1CZ5A 1HYOA 5GLFA 3HU1A 4AS1A 3V77A 3HU3A 2EB5A 5CCBA 2QQSA 3TIWA 4DBHA 5D6XA 2GF7A 4UC4A 3QQ7A 2PWYA 2DFUA 3FPTA 1SAWA 1WZOA 1CR5A 1I9GA 2Q1CX 5D2HA 3ZGZA 1S3SA 1QQJA 1I7OA 2MM0A 5CD1A 5FTLA 5B6CA 4KODA 1NR9A 1NKQA 1QDNA 5D2GA 1WLFA 1O54A 1R7RA 3ZJVA 2EB6A 2LW6A 5D2IA 2XDPA 4AQ7A 2Q18X 2Q1AX 3MB5A 2EB4A 3CF2A 1E32A 3ZJTA 5EPPA 5DYIA 3QC8A 3LZKA 4DBFA 5C18A 1ZC1A 2HZYA 2KY9A 5FTNA 5FTJA 2YVLA 1QCSA 5DYGA 3HU2A 4KO8A 4CQNA 4RV0A 2Q19X 1CZ4A 2GFAA 5FTMA 3ZJUA 2Q1DX 5ERGB 4FIBA 4KLNA 3QQ8A 3LGAA 5D2FA 5D6WA 4MAQA 1SV6A 4QKUA 2WQTA 2JV2A 5FTKA 1QCOA 5D2JA 3FPRA 3FPUA 1GTTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QDF A;  4DBH A;  3R6O A;  3S52 A;  2EB6 A;  5D2I A;  2Q19 X;  2DFU A;  1SAW A;  3RR6 A;  1WZO A;  2Q1C X;  5D2H A;  2Q18 X;  2Q1D X;  2Q1A X;  3BQB A;  2EB4 A;  1QCN A;  1QQJ A;  1I7O A;  5D2F A;  4MAQ A;  5D2K A;  1SV6 A;  4PFZ A;  1HYO A;  4QKU A;  2WQT A;  3LZK A;  4DBF A;  1QCO A;  1NR9 A;  5D2J A;  3V77 A;  1NKQ A;  2EB5 A;  1GTT A;  2HZY A;  5D2G A; 
#chains in the Genus database with same CATH topology
 2QQR A;  3QDF A;  4ARI A;  3R6O A;  2PJH B;  3S52 A;  2B25 A;  3RR6 A;  5CCX A;  3BQB A;  3LHD A;  5C1B A;  1QCN A;  3QWZ A;  5D6Y A;  4ARC A;  2YUJ A;  4KDI A;  5EQJ B;  5D2K A;  2MM2 A;  4KDL A;  4PFZ A;  1CZ5 A;  1HYO A;  5GLF A;  3HU1 A;  4AS1 A;  3V77 A;  3HU3 A;  2EB5 A;  5CCB A;  2QQS A;  3TIW A;  4DBH A;  5D6X A;  2GF7 A;  4UC4 A;  3QQ7 A;  2PWY A;  2DFU A;  3FPT A;  1SAW A;  1WZO A;  1CR5 A;  1I9G A;  2Q1C X;  5D2H A;  3ZGZ A;  1S3S A;  1QQJ A;  1I7O A;  2MM0 A;  5CD1 A;  5FTL A;  5B6C A;  4KOD A;  1NR9 A;  1NKQ A;  1QDN A;  5D2G A;  1WLF A;  1O54 A;  1R7R A;  3ZJV A;  2EB6 A;  2LW6 A;  5D2I A;  2XDP A;  4AQ7 A;  2Q18 X;  2Q1A X;  3MB5 A;  2EB4 A;  3CF2 A;  1E32 A;  3ZJT A;  5EPP A;  5DYI A;  3QC8 A;  3LZK A;  4DBF A;  5C18 A;  1ZC1 A;  2HZY A;  2KY9 A;  5FTN A;  5FTJ A;  2YVL A;  1QCS A;  5DYG A;  3HU2 A;  4KO8 A;  4CQN A;  4RV0 A;  2Q19 X;  1CZ4 A;  2GFA A;  5FTM A;  3ZJU A;  2Q1D X;  5ERG B;  4FIB A;  4KLN A;  3QQ8 A;  3LGA A;  5D2F A;  5D6W A;  4MAQ A;  1SV6 A;  4QKU A;  2WQT A;  2JV2 A;  5FTK A;  1QCO A;  5D2J A;  3FPR A;  3FPU A;  1GTT A; 
#chains in the Genus database with same CATH homology
 2QQR A;  3QDF A;  4ARI A;  3R6O A;  2PJH B;  3S52 A;  2B25 A;  3RR6 A;  5CCX A;  3BQB A;  3LHD A;  5C1B A;  1QCN A;  3QWZ A;  5D6Y A;  4ARC A;  2YUJ A;  4KDI A;  5EQJ B;  5D2K A;  2MM2 A;  4KDL A;  4PFZ A;  1CZ5 A;  1HYO A;  5GLF A;  3HU1 A;  4AS1 A;  3V77 A;  3HU3 A;  2EB5 A;  5CCB A;  2QQS A;  3TIW A;  4DBH A;  5D6X A;  2GF7 A;  4UC4 A;  3QQ7 A;  2PWY A;  2DFU A;  3FPT A;  1SAW A;  1WZO A;  1CR5 A;  1I9G A;  2Q1C X;  5D2H A;  3ZGZ A;  1S3S A;  1QQJ A;  1I7O A;  2MM0 A;  5CD1 A;  5FTL A;  5B6C A;  4KOD A;  1NR9 A;  1NKQ A;  1QDN A;  5D2G A;  1WLF A;  1O54 A;  1R7R A;  3ZJV A;  2EB6 A;  2LW6 A;  5D2I A;  2XDP A;  4AQ7 A;  2Q18 X;  2Q1A X;  3MB5 A;  2EB4 A;  3CF2 A;  1E32 A;  3ZJT A;  5EPP A;  5DYI A;  3QC8 A;  3LZK A;  4DBF A;  5C18 A;  1ZC1 A;  2HZY A;  2KY9 A;  5FTN A;  5FTJ A;  2YVL A;  1QCS A;  5DYG A;  3HU2 A;  4KO8 A;  4CQN A;  4RV0 A;  2Q19 X;  1CZ4 A;  2GFA A;  5FTM A;  3ZJU A;  2Q1D X;  5ERG B;  4FIB A;  4KLN A;  3QQ8 A;  3LGA A;  5D2F A;  5D6W A;  4MAQ A;  1SV6 A;  4QKU A;  2WQT A;  2JV2 A;  5FTK A;  1QCO A;  5D2J A;  3FPR A;  3FPU A;  1GTT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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