2Q1CX

2-keto-3-deoxy-d-arabinonate dehydratase complexed with calcium and 2-oxobutyrate
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
291
structure length
291
Chain Sequence
MKLFRVVKRGYYISYAILDNSTIIRLDEDPIKALMRYSENKEVLGDRVTGIDYQSLLKSFQINDIRITKPIDPPEVWGSGISYEMARERYSEENVAKILGKTIYEKVYDAVRPEIFFKATPNRCVGHGEAIAVRSDSEWTLPEPELAVVLDSNGKILGYTIMDDVSARDLEAENPLYLPQSKIYAGCCAFGPVIVTSDEIKNPYSLDITLKIVREGRVFFEGSVNTNKMRRKIEEQIQYLIRDNPIPDGTILTTGTAIVPGRDKGLKDEDIVEITISNIGTLITPVKKRRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
pubmed doi rcsb
molecule keywords 2-keto-3-deoxy-D-arabinonate dehydratase
molecule tags Lyase
source organism Sulfolobus solfataricus
total genus 74
structure length 291
sequence length 291
ec nomenclature ec 4.2.1.141: 2-dehydro-3-deoxy-D-arabinonate dehydratase.
pdb deposition date 2007-05-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01557 FAA_hydrolase Fumarylacetoacetate (FAA) hydrolase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.330.40 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 2q1cX01
3.90.850.10 Alpha Beta Alpha-Beta Complex Fumarylacetoacetate hydrolase; domain 2 Fumarylacetoacetase-like, C-terminal domain 2q1cX02
3R6OA 2Q19X 2EB4A 4DBHA 4DBFA 3S52A 4MAQA 1NKQA 3BQBA 2WQTA 3V77A 2Q1CX 1SAWA 1WZOA 4QKUA 5D2GA 2Q1AX 4PFZA 5D2JA 2Q18X 5D2IA 1GTTA 1SV6A 2Q1DX 5D2KA 2EB5A 3LZKA 1QCNA 5D2HA 2DFUA 1QQJA 2EB6A 1QCOA 1I7OA 5D2FA 1HYOA 3RR6A 2HZYA 3QDFA 1NR9A
chains in the Genus database with same CATH superfamily
3LHDA 1S3SA 5FTMA 4MAQA 3BQBA 1QCSA 3QQ8A 2YVLA 5DYGA 5EQJB 5CCXA 3QQ7A 5D2IA 4AQ7A 1GTTA 5D6XA 3ZJUA 3TIWA 2Q1DX 2MM2A 5D2KA 5D2HA 5CCBA 1QQJA 5ERGB 5GLFA 5D2FA 4ARIA 3ZGZA 3HU3A 3FPUA 1CZ4A 3HU2A 1O54A 5D6WA 3LGAA 3R6OA 3S52A 1NKQA 2QQSA 1WZOA 5D2GA 3FPTA 5CD1A 2Q1AX 4PFZA 1E32A 3CF2A 2QQRA 3LZKA 1QCNA 2DFUA 1QDNA 1CR5A 3MB5A 1I7OA 2HZYA 1ZC1A 4RV0A 4DBHA 4KO8A 2WQTA 5FTJA 2Q1CX 5EPPA 1SAWA 4UC4A 1WLFA 2KY9A 5FTNA 4QKUA 3QWZA 5D2JA 2B25A 4ARCA 1SV6A 5DYIA 2JV2A 4FIBA 2GF7A 5FTKA 1QCOA 4KODA 3RR6A 4KDLA 5C1BA 5D6YA 5FTLA 2Q19X 4AS1A 2GFAA 2EB4A 5B6CA 4DBFA 3V77A 3QC8A 3HU1A 1R7RA 3ZJVA 2PJHB 2XDPA 4CQNA 2YUJA 2Q18X 2LW6A 3FPRA 2EB5A 2EB6A 1CZ5A 1I9GA 4KDIA 1HYOA 5C18A 4KLNA 3QDFA 2PWYA 3ZJTA 2MM0A 1NR9A
chains in the Genus database with same CATH topology
3LHDA 1S3SA 5FTMA 4MAQA 3BQBA 1QCSA 3QQ8A 2YVLA 5DYGA 5EQJB 5CCXA 3QQ7A 5D2IA 4AQ7A 1GTTA 5D6XA 3ZJUA 3TIWA 2Q1DX 2MM2A 5D2KA 5D2HA 5CCBA 1QQJA 5ERGB 5GLFA 5D2FA 4ARIA 3ZGZA 3HU3A 3FPUA 1CZ4A 3HU2A 1O54A 5D6WA 3LGAA 3R6OA 3S52A 1NKQA 2QQSA 1WZOA 5D2GA 3FPTA 5CD1A 2Q1AX 4PFZA 1E32A 3CF2A 2QQRA 3LZKA 1QCNA 2DFUA 1QDNA 1CR5A 3MB5A 1I7OA 2HZYA 1ZC1A 4RV0A 4DBHA 4KO8A 2WQTA 5FTJA 2Q1CX 5EPPA 1SAWA 4UC4A 1WLFA 2KY9A 5FTNA 4QKUA 3QWZA 5D2JA 2B25A 4ARCA 1SV6A 5DYIA 2JV2A 4FIBA 2GF7A 5FTKA 1QCOA 4KODA 3RR6A 4KDLA 5C1BA 5D6YA 5FTLA 2Q19X 4AS1A 2GFAA 2EB4A 5B6CA 4DBFA 3V77A 3QC8A 3HU1A 1R7RA 3ZJVA 2PJHB 2XDPA 4CQNA 2YUJA 2Q18X 2LW6A 3FPRA 2EB5A 2EB6A 1CZ5A 1I9GA 4KDIA 1HYOA 5C18A 4KLNA 3QDFA 2PWYA 3ZJTA 2MM0A 1NR9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3R6O A;  2Q19 X;  2EB4 A;  4DBH A;  4DBF A;  3S52 A;  4MAQ A;  1NKQ A;  3BQB A;  2WQT A;  3V77 A;  2Q1C X;  1SAW A;  1WZO A;  4QKU A;  5D2G A;  2Q1A X;  4PFZ A;  5D2J A;  2Q18 X;  5D2I A;  1GTT A;  1SV6 A;  2Q1D X;  5D2K A;  2EB5 A;  3LZK A;  1QCN A;  5D2H A;  2DFU A;  1QQJ A;  2EB6 A;  1QCO A;  1I7O A;  5D2F A;  1HYO A;  3RR6 A;  2HZY A;  3QDF A;  1NR9 A; 
#chains in the Genus database with same CATH topology
 3LHD A;  1S3S A;  5FTM A;  4MAQ A;  3BQB A;  1QCS A;  3QQ8 A;  2YVL A;  5DYG A;  5EQJ B;  5CCX A;  3QQ7 A;  5D2I A;  4AQ7 A;  1GTT A;  5D6X A;  3ZJU A;  3TIW A;  2Q1D X;  2MM2 A;  5D2K A;  5D2H A;  5CCB A;  1QQJ A;  5ERG B;  5GLF A;  5D2F A;  4ARI A;  3ZGZ A;  3HU3 A;  3FPU A;  1CZ4 A;  3HU2 A;  1O54 A;  5D6W A;  3LGA A;  3R6O A;  3S52 A;  1NKQ A;  2QQS A;  1WZO A;  5D2G A;  3FPT A;  5CD1 A;  2Q1A X;  4PFZ A;  1E32 A;  3CF2 A;  2QQR A;  3LZK A;  1QCN A;  2DFU A;  1QDN A;  1CR5 A;  3MB5 A;  1I7O A;  2HZY A;  1ZC1 A;  4RV0 A;  4DBH A;  4KO8 A;  2WQT A;  5FTJ A;  2Q1C X;  5EPP A;  1SAW A;  4UC4 A;  1WLF A;  2KY9 A;  5FTN A;  4QKU A;  3QWZ A;  5D2J A;  2B25 A;  4ARC A;  1SV6 A;  5DYI A;  2JV2 A;  4FIB A;  2GF7 A;  5FTK A;  1QCO A;  4KOD A;  3RR6 A;  4KDL A;  5C1B A;  5D6Y A;  5FTL A;  2Q19 X;  4AS1 A;  2GFA A;  2EB4 A;  5B6C A;  4DBF A;  3V77 A;  3QC8 A;  3HU1 A;  1R7R A;  3ZJV A;  2PJH B;  2XDP A;  4CQN A;  2YUJ A;  2Q18 X;  2LW6 A;  3FPR A;  2EB5 A;  2EB6 A;  1CZ5 A;  1I9G A;  4KDI A;  1HYO A;  5C18 A;  4KLN A;  3QDF A;  2PWY A;  3ZJT A;  2MM0 A;  1NR9 A; 
#chains in the Genus database with same CATH homology
 3LHD A;  1S3S A;  5FTM A;  4MAQ A;  3BQB A;  1QCS A;  3QQ8 A;  2YVL A;  5DYG A;  5EQJ B;  5CCX A;  3QQ7 A;  5D2I A;  4AQ7 A;  1GTT A;  5D6X A;  3ZJU A;  3TIW A;  2Q1D X;  2MM2 A;  5D2K A;  5D2H A;  5CCB A;  1QQJ A;  5ERG B;  5GLF A;  5D2F A;  4ARI A;  3ZGZ A;  3HU3 A;  3FPU A;  1CZ4 A;  3HU2 A;  1O54 A;  5D6W A;  3LGA A;  3R6O A;  3S52 A;  1NKQ A;  2QQS A;  1WZO A;  5D2G A;  3FPT A;  5CD1 A;  2Q1A X;  4PFZ A;  1E32 A;  3CF2 A;  2QQR A;  3LZK A;  1QCN A;  2DFU A;  1QDN A;  1CR5 A;  3MB5 A;  1I7O A;  2HZY A;  1ZC1 A;  4RV0 A;  4DBH A;  4KO8 A;  2WQT A;  5FTJ A;  2Q1C X;  5EPP A;  1SAW A;  4UC4 A;  1WLF A;  2KY9 A;  5FTN A;  4QKU A;  3QWZ A;  5D2J A;  2B25 A;  4ARC A;  1SV6 A;  5DYI A;  2JV2 A;  4FIB A;  2GF7 A;  5FTK A;  1QCO A;  4KOD A;  3RR6 A;  4KDL A;  5C1B A;  5D6Y A;  5FTL A;  2Q19 X;  4AS1 A;  2GFA A;  2EB4 A;  5B6C A;  4DBF A;  3V77 A;  3QC8 A;  3HU1 A;  1R7R A;  3ZJV A;  2PJH B;  2XDP A;  4CQN A;  2YUJ A;  2Q18 X;  2LW6 A;  3FPR A;  2EB5 A;  2EB6 A;  1CZ5 A;  1I9G A;  4KDI A;  1HYO A;  5C18 A;  4KLN A;  3QDF A;  2PWY A;  3ZJT A;  2MM0 A;  1NR9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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