2EB6A

Crystal structure of hpcg complexed with mg ion
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
267
structure length
267
Chain Sequence
MFDKHTHTLIAQRLDQAEKQREQIRAISLDYPEITIEDAYAVQREWVRLKIAEGRTLKGHKIGLTSKAMQASSQISEPDYGALLDDMFFHDGSDIPTDRFIVPRIEVELAFVLAKPLRGPNCTLFDVYNATDYVIPALELIDARCHNIDPETQRPRKVFDTISDNAANAGVILGGRPIKPDELDLRWISALMYRNGVIEETGVAAGVLNHPANGVAWLANKLAPYDVQLEAGQIILGGSFTRPVPARKGDTFHVDYGNMGSISCRFV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and Mechanism of HpcG, a Hydratase in the Homoprotocatechuate Degradation Pathway of Escherichia coli
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords 2-oxo-hept-3-ene-1,7-dioate hydratase
total genus 85
structure length 267
sequence length 267
chains with identical sequence B, C, D, E
ec nomenclature ec 4.2.1.-:
pdb deposition date 2007-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01557 FAA_hydrolase Fumarylacetoacetate (FAA) hydrolase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.850.10 Alpha Beta Alpha-Beta Complex Fumarylacetoacetate hydrolase; domain 2 Fumarylacetoacetase-like, C-terminal domain 2eb6A00
2EB6A 1QCNA 4DBFA 2DFUA 2Q19X 3S52A 2HZYA 3QDFA 5D2HA 4DBHA 5D2FA 2EB5A 1NR9A 5D2IA 2Q1DX 1GTTA 1SAWA 1QCOA 5D2KA 4MAQA 1QQJA 3BQBA 1I7OA 5D2GA 5D2JA 3LZKA 3R6OA 2Q1CX 2Q1AX 2Q18X 1NKQA 2WQTA 1HYOA 4PFZA 2EB4A 1WZOA 3RR6A 4QKUA 3V77A 1SV6A
chains in the Genus database with same CATH superfamily
2EB6A 1QCNA 4DBFA 2DFUA 2Q19X 3S52A 2HZYA 3QDFA 5D2HA 4DBHA 5D2FA 2EB5A 1NR9A 5D2IA 2Q1DX 1GTTA 1SAWA 1QCOA 5D2KA 4MAQA 1QQJA 3BQBA 1I7OA 5D2GA 5D2JA 3LZKA 3R6OA 2Q1CX 2Q1AX 2Q18X 1NKQA 2WQTA 1HYOA 4PFZA 2EB4A 1WZOA 3RR6A 4QKUA 3V77A 1SV6A
chains in the Genus database with same CATH topology
2EB6A 1QCNA 4DBFA 2DFUA 2Q19X 3S52A 2HZYA 3QDFA 5D2HA 4DBHA 5D2FA 2EB5A 1NR9A 5D2IA 2Q1DX 1GTTA 1SAWA 1QCOA 5D2KA 4MAQA 1QQJA 3BQBA 1I7OA 5D2GA 5D2JA 3LZKA 3R6OA 2Q1CX 2Q1AX 2Q18X 1NKQA 2WQTA 1HYOA 4PFZA 2EB4A 1WZOA 3RR6A 4QKUA 3V77A 1SV6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EB6 A;  1QCN A;  4DBF A;  2DFU A;  2Q19 X;  3S52 A;  2HZY A;  3QDF A;  5D2H A;  4DBH A;  5D2F A;  2EB5 A;  1NR9 A;  5D2I A;  2Q1D X;  1GTT A;  1SAW A;  1QCO A;  5D2K A;  4MAQ A;  1QQJ A;  3BQB A;  1I7O A;  5D2G A;  5D2J A;  3LZK A;  3R6O A;  2Q1C X;  2Q1A X;  2Q18 X;  1NKQ A;  2WQT A;  1HYO A;  4PFZ A;  2EB4 A;  1WZO A;  3RR6 A;  4QKU A;  3V77 A;  1SV6 A; 
#chains in the Genus database with same CATH topology
 2EB6 A;  1QCN A;  4DBF A;  2DFU A;  2Q19 X;  3S52 A;  2HZY A;  3QDF A;  5D2H A;  4DBH A;  5D2F A;  2EB5 A;  1NR9 A;  5D2I A;  2Q1D X;  1GTT A;  1SAW A;  1QCO A;  5D2K A;  4MAQ A;  1QQJ A;  3BQB A;  1I7O A;  5D2G A;  5D2J A;  3LZK A;  3R6O A;  2Q1C X;  2Q1A X;  2Q18 X;  1NKQ A;  2WQT A;  1HYO A;  4PFZ A;  2EB4 A;  1WZO A;  3RR6 A;  4QKU A;  3V77 A;  1SV6 A; 
#chains in the Genus database with same CATH homology
 2EB6 A;  1QCN A;  4DBF A;  2DFU A;  2Q19 X;  3S52 A;  2HZY A;  3QDF A;  5D2H A;  4DBH A;  5D2F A;  2EB5 A;  1NR9 A;  5D2I A;  2Q1D X;  1GTT A;  1SAW A;  1QCO A;  5D2K A;  4MAQ A;  1QQJ A;  3BQB A;  1I7O A;  5D2G A;  5D2J A;  3LZK A;  3R6O A;  2Q1C X;  2Q1A X;  2Q18 X;  1NKQ A;  2WQT A;  1HYO A;  4PFZ A;  2EB4 A;  1WZO A;  3RR6 A;  4QKU A;  3V77 A;  1SV6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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