2GTYA

Crystal structure of unliganded griffithsin
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
121
structure length
121
Chain Sequence
SLTHRKFGGSGGSPFSGLSSIAVRSGSYLDAIIIDGVHHGGSGGNLSPTFTFGSGEYISNMTIRSGDYIDNISFETNMGRRFGPYGGSGGSANTLSNVKVIQINGSAGDYLDSLDIYYEQY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Sugar binding protein
source organism Griffithsia
publication title Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding.
pubmed doi rcsb
molecule keywords Griffithsin
total genus 17
structure length 121
sequence length 121
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01419 Jacalin Jacalin-like lectin domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.100.10.30 Mainly Beta Aligned Prism Vitelline Membrane Outer Layer Protein I, subunit A Jacalin-like lectin domain 2gtyA01
1KUJA 1UGYA 4GX7A 1XXQA 2HYRA 3LL0A 3R51A 3APAA 1VBOA 4PITA 3VZGA 1J4UA 1ZGRA 1OUWA 2GUCA 5J51A 2BN0A 3WOCA 5BN6E 3LKYA 3LLYA 1J4TA 3P8SA 1UGXA 1JACA 1UH1A 3LLZA 1UH0A 4PIFA 5J50A 1TP8A 2GUXA 3VY6A 1J4SA 3LM1A 5EXGA 2NUOA 1PXDA 4MQ0A 3LL2A 1C3NA 3AQGA 3VZFA 3MIVA 2JZ4A 3R50A 4PIKA 4AK4A 1XXRA 2GUDA 2GUEA 2HYQA 5AV7A 1TOQA 4R6PA 2BMYA 4WOGA 1C3KA 1JOTA 4AKDA 3MIUA 4AKCA 3MITA 2NU5A 4R6QA 3VY7A 2GTYA 3O44A 1UGWC 3WOBA 1UGWA 3VZEA 4AKBA 1XEZA 1ZGSA 1C3MA 1M26A 5J4TA 3LL1A 1WS4C 1WS4A 2BMZA 5J4XA 1WS5C 4R6NA 4R6RA 5JM1A 1WS5A 4PIUA 3R52A 4DDNA 4R6OA 1KU8A 1VBPA 1X1VA 1UGYC
chains in the Genus database with same CATH superfamily
1KUJA 1UGYA 4GX7A 1XXQA 2HYRA 3LL0A 3R51A 3APAA 1VBOA 4PITA 3VZGA 1J4UA 1ZGRA 1OUWA 1VMOA 2GUCA 4ARYA 1I5PA 5J51A 2BN0A 4QX2A 3WOCA 5BN6E 2C9KA 3LKYA 3LLYA 1J4TA 3P8SA 1UGXA 1W99A 1JACA 1UH1A 3LLZA 1UH0A 4PIFA 5J50A 4QX0A 3EB7A 1TP8A 2GUXA 4MOAA 3VY6A 1J4SA 3LM1A 5EXGA 2NUOA 1PXDA 4MQ0A 3LL2A 1C3NA 3AQGA 3VZFA 3MIVA 4W8JA 2JZ4A 3R50A 4D8MA 4PIKA 4AK4A 1XXRA 2GUDA 2GUEA 2HYQA 5AV7A 1TOQA 4R6PA 2BMYA 4WOGA 1C3KA 1DLCA 1JOTA 4AKDA 3MIUA 4AKCA 3MITA 1CIYA 2NU5A 4R6QA 3VY7A 2GTYA 3O44A 1UGWC 3WOBA 1UGWA 3VZEA 4AKBA 1XEZA 3TOWA 1ZGSA 1C3MA 1M26A 2QP2A 4QX3A 5J4TA 3LL1A 1WS4C 1WS4A 1JI6A 2BMZA 5J4XA 1WS5C 4R6NA 4R6RA 5JM1A 1WS5A 4PIUA 3R52A 4DDNA 4ARXA 4R6OA 1KU8A 1VBPA 1X1VA 4QX1A 1UGYC
chains in the Genus database with same CATH topology
1KUJA 1UGYA 4GX7A 1XXQA 2HYRA 3LL0A 3R51A 3APAA 1VBOA 4PITA 3VZGA 1J4UA 1ZGRA 1OUWA 2GUCA 5J51A 2BN0A 3WOCA 5BN6E 3LKYA 3LLYA 1J4TA 3P8SA 1UGXA 1JACA 1UH1A 3LLZA 1UH0A 4PIFA 5J50A 1TP8A 2GUXA 3VY6A 1J4SA 3LM1A 5EXGA 2NUOA 1PXDA 4MQ0A 3LL2A 1C3NA 3AQGA 3VZFA 3MIVA 2JZ4A 3R50A 4PIKA 4AK4A 1XXRA 2GUDA 2GUEA 2HYQA 5AV7A 1TOQA 4R6PA 2BMYA 4WOGA 1C3KA 1JOTA 4AKDA 3MIUA 4AKCA 3MITA 2NU5A 4R6QA 3VY7A 2GTYA 3O44A 1UGWC 3WOBA 1UGWA 3VZEA 4AKBA 1XEZA 1ZGSA 1C3MA 1M26A 5J4TA 3LL1A 1WS4C 1WS4A 2BMZA 5J4XA 1WS5C 4R6NA 4R6RA 5JM1A 1WS5A 4PIUA 3R52A 4DDNA 4R6OA 1KU8A 1VBPA 1X1VA 1UGYC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KUJ A;  1UGY A;  4GX7 A;  1XXQ A;  2HYR A;  3LL0 A;  3R51 A;  3APA A;  1VBO A;  4PIT A;  3VZG A;  1J4U A;  1ZGR A;  1OUW A;  2GUC A;  5J51 A;  2BN0 A;  3WOC A;  5BN6 E;  3LKY A;  3LLY A;  1J4T A;  3P8S A;  1UGX A;  1JAC A;  1UH1 A;  3LLZ A;  1UH0 A;  4PIF A;  5J50 A;  1TP8 A;  2GUX A;  3VY6 A;  1J4S A;  3LM1 A;  5EXG A;  2NUO A;  1PXD A;  4MQ0 A;  3LL2 A;  1C3N A;  3AQG A;  3VZF A;  3MIV A;  2JZ4 A;  3R50 A;  4PIK A;  4AK4 A;  1XXR A;  2GUD A;  2GUE A;  2HYQ A;  5AV7 A;  1TOQ A;  4R6P A;  2BMY A;  4WOG A;  1C3K A;  1JOT A;  4AKD A;  3MIU A;  4AKC A;  3MIT A;  2NU5 A;  4R6Q A;  3VY7 A;  2GTY A;  3O44 A;  1UGW C;  3WOB A;  1UGW A;  3VZE A;  4AKB A;  1XEZ A;  1ZGS A;  1C3M A;  1M26 A;  5J4T A;  3LL1 A;  1WS4 C;  1WS4 A;  2BMZ A;  5J4X A;  1WS5 C;  4R6N A;  4R6R A;  5JM1 A;  1WS5 A;  4PIU A;  3R52 A;  4DDN A;  4R6O A;  1KU8 A;  1VBP A;  1X1V A;  1UGY C; 
#chains in the Genus database with same CATH topology
 1KUJ A;  1UGY A;  4GX7 A;  1XXQ A;  2HYR A;  3LL0 A;  3R51 A;  3APA A;  1VBO A;  4PIT A;  3VZG A;  1J4U A;  1ZGR A;  1OUW A;  1VMO A;  2GUC A;  4ARY A;  1I5P A;  5J51 A;  2BN0 A;  4QX2 A;  3WOC A;  5BN6 E;  2C9K A;  3LKY A;  3LLY A;  1J4T A;  3P8S A;  1UGX A;  1W99 A;  1JAC A;  1UH1 A;  3LLZ A;  1UH0 A;  4PIF A;  5J50 A;  4QX0 A;  3EB7 A;  1TP8 A;  2GUX A;  4MOA A;  3VY6 A;  1J4S A;  3LM1 A;  5EXG A;  2NUO A;  1PXD A;  4MQ0 A;  3LL2 A;  1C3N A;  3AQG A;  3VZF A;  3MIV A;  4W8J A;  2JZ4 A;  3R50 A;  4D8M A;  4PIK A;  4AK4 A;  1XXR A;  2GUD A;  2GUE A;  2HYQ A;  5AV7 A;  1TOQ A;  4R6P A;  2BMY A;  4WOG A;  1C3K A;  1DLC A;  1JOT A;  4AKD A;  3MIU A;  4AKC A;  3MIT A;  1CIY A;  2NU5 A;  4R6Q A;  3VY7 A;  2GTY A;  3O44 A;  1UGW C;  3WOB A;  1UGW A;  3VZE A;  4AKB A;  1XEZ A;  3TOW A;  1ZGS A;  1C3M A;  1M26 A;  2QP2 A;  4QX3 A;  5J4T A;  3LL1 A;  1WS4 C;  1WS4 A;  1JI6 A;  2BMZ A;  5J4X A;  1WS5 C;  4R6N A;  4R6R A;  5JM1 A;  1WS5 A;  4PIU A;  3R52 A;  4DDN A;  4ARX A;  4R6O A;  1KU8 A;  1VBP A;  1X1V A;  4QX1 A;  1UGY C; 
#chains in the Genus database with same CATH homology
 1KUJ A;  1UGY A;  4GX7 A;  1XXQ A;  2HYR A;  3LL0 A;  3R51 A;  3APA A;  1VBO A;  4PIT A;  3VZG A;  1J4U A;  1ZGR A;  1OUW A;  2GUC A;  5J51 A;  2BN0 A;  3WOC A;  5BN6 E;  3LKY A;  3LLY A;  1J4T A;  3P8S A;  1UGX A;  1JAC A;  1UH1 A;  3LLZ A;  1UH0 A;  4PIF A;  5J50 A;  1TP8 A;  2GUX A;  3VY6 A;  1J4S A;  3LM1 A;  5EXG A;  2NUO A;  1PXD A;  4MQ0 A;  3LL2 A;  1C3N A;  3AQG A;  3VZF A;  3MIV A;  2JZ4 A;  3R50 A;  4PIK A;  4AK4 A;  1XXR A;  2GUD A;  2GUE A;  2HYQ A;  5AV7 A;  1TOQ A;  4R6P A;  2BMY A;  4WOG A;  1C3K A;  1JOT A;  4AKD A;  3MIU A;  4AKC A;  3MIT A;  2NU5 A;  4R6Q A;  3VY7 A;  2GTY A;  3O44 A;  1UGW C;  3WOB A;  1UGW A;  3VZE A;  4AKB A;  1XEZ A;  1ZGS A;  1C3M A;  1M26 A;  5J4T A;  3LL1 A;  1WS4 C;  1WS4 A;  2BMZ A;  5J4X A;  1WS5 C;  4R6N A;  4R6R A;  5JM1 A;  1WS5 A;  4PIU A;  3R52 A;  4DDN A;  4R6O A;  1KU8 A;  1VBP A;  1X1V A;  1UGY C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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