2GUEA

Crystal structure of a complex of griffithsin with n-acetylglucosamine
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
121
structure length
121
Chain Sequence
SLTHRKFGGSGGSPFSGLSSIAVRSGSYLDAIIIDGVHHGGSGGNLSPTFTFGSGEYISNMTIRSGDYIDNISFETNMGRRFGPYGGSGGSANTLSNVKVIQINGSAGDYLDSLDIYYEQY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Griffithsia
molecule keywords griffithsin
total genus 16
structure length 121
sequence length 121
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01419 Jacalin Jacalin-like lectin domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.100.10.30 Mainly Beta Aligned Prism Vitelline Membrane Outer Layer Protein I, subunit A Jacalin-like lectin domain 2gueA01
2GUXA 4R6QA 5BN6E 1UGXA 3MIUA 1XXRA 1XXQA 4R6NA 3LL1A 1J4TA 2BN0A 1ZGRA 3AQGA 4AK4A 3R50A 3R52A 1KUJA 1PXDA 1WS5C 1WS4C 4R6OA 5JM1A 1WS5A 1WS4A 3VY6A 3LKYA 3VZGA 3APAA 3LM1A 1OUWA 2BMYA 4PITA 5EXGA 5AV7A 3VZEA 1VBPA 2HYQA 5J4XA 1X1VA 1J4SA 4AKBA 3LLYA 3WOBA 1UGWC 2NUOA 4AKDA 1UGWA 3LL2A 2JZ4A 4PIKA 1UH1A 4WOGA 5J50A 1UGYC 1C3NA 2GTYA 3LLZA 1UGYA 4GX7A 1JOTA 2HYRA 3VZFA 3MITA 4R6RA 2BMZA 2GUEA 2GUCA 3P8SA 3VY7A 1ZGSA 5J51A 4AKCA 1XEZA 4R6PA 1J4UA 3LL0A 3R51A 1TOQA 3WOCA 4DDNA 1VBOA 3MIVA 4PIFA 1KU8A 2NU5A 2GUDA 1TP8A 1M26A 3O44A 1JACA 4MQ0A 5J4TA 1C3KA 4PIUA 1UH0A 1C3MA
chains in the Genus database with same CATH superfamily
4QX3A 2GUXA 4R6QA 5BN6E 1UGXA 3MIUA 4QX1A 1XXRA 1I5PA 1XXQA 4R6NA 3LL1A 1J4TA 2BN0A 1ZGRA 3AQGA 4AK4A 3R50A 3R52A 1KUJA 1PXDA 3TOWA 1WS5C 1WS4C 4R6OA 5JM1A 1WS5A 1WS4A 3VY6A 4D8MA 3LKYA 3VZGA 3APAA 3LM1A 1OUWA 2BMYA 4PITA 5EXGA 4W8JA 5AV7A 3VZEA 1VBPA 1CIYA 2HYQA 5J4XA 1X1VA 1J4SA 4AKBA 3LLYA 3WOBA 1UGWC 2NUOA 4AKDA 1UGWA 3LL2A 1VMOA 2JZ4A 4PIKA 1UH1A 4WOGA 5J50A 4QX2A 1UGYC 1C3NA 2GTYA 3LLZA 1UGYA 4GX7A 1JOTA 4MOAA 2HYRA 3VZFA 4QX0A 3MITA 4R6RA 1DLCA 4ARXA 2BMZA 2GUEA 2GUCA 3P8SA 3VY7A 1ZGSA 1W99A 5J51A 4AKCA 1XEZA 4R6PA 1J4UA 3LL0A 3R51A 3EB7A 1TOQA 3WOCA 2QP2A 4DDNA 1VBOA 3MIVA 4PIFA 1KU8A 2NU5A 2GUDA 1TP8A 1M26A 3O44A 1JI6A 1JACA 2C9KA 4MQ0A 4ARYA 5J4TA 1C3KA 4PIUA 1UH0A 1C3MA
chains in the Genus database with same CATH topology
2GUXA 4R6QA 5BN6E 1UGXA 3MIUA 1XXRA 1XXQA 4R6NA 3LL1A 1J4TA 2BN0A 1ZGRA 3AQGA 4AK4A 3R50A 3R52A 1KUJA 1PXDA 1WS5C 1WS4C 4R6OA 5JM1A 1WS5A 1WS4A 3VY6A 3LKYA 3VZGA 3APAA 3LM1A 1OUWA 2BMYA 4PITA 5EXGA 5AV7A 3VZEA 1VBPA 2HYQA 5J4XA 1X1VA 1J4SA 4AKBA 3LLYA 3WOBA 1UGWC 2NUOA 4AKDA 1UGWA 3LL2A 2JZ4A 4PIKA 1UH1A 4WOGA 5J50A 1UGYC 1C3NA 2GTYA 3LLZA 1UGYA 4GX7A 1JOTA 2HYRA 3VZFA 3MITA 4R6RA 2BMZA 2GUEA 2GUCA 3P8SA 3VY7A 1ZGSA 5J51A 4AKCA 1XEZA 4R6PA 1J4UA 3LL0A 3R51A 1TOQA 3WOCA 4DDNA 1VBOA 3MIVA 4PIFA 1KU8A 2NU5A 2GUDA 1TP8A 1M26A 3O44A 1JACA 4MQ0A 5J4TA 1C3KA 4PIUA 1UH0A 1C3MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GUX A;  4R6Q A;  5BN6 E;  1UGX A;  3MIU A;  1XXR A;  1XXQ A;  4R6N A;  3LL1 A;  1J4T A;  2BN0 A;  1ZGR A;  3AQG A;  4AK4 A;  3R50 A;  3R52 A;  1KUJ A;  1PXD A;  1WS5 C;  1WS4 C;  4R6O A;  5JM1 A;  1WS5 A;  1WS4 A;  3VY6 A;  3LKY A;  3VZG A;  3APA A;  3LM1 A;  1OUW A;  2BMY A;  4PIT A;  5EXG A;  5AV7 A;  3VZE A;  1VBP A;  2HYQ A;  5J4X A;  1X1V A;  1J4S A;  4AKB A;  3LLY A;  3WOB A;  1UGW C;  2NUO A;  4AKD A;  1UGW A;  3LL2 A;  2JZ4 A;  4PIK A;  1UH1 A;  4WOG A;  5J50 A;  1UGY C;  1C3N A;  2GTY A;  3LLZ A;  1UGY A;  4GX7 A;  1JOT A;  2HYR A;  3VZF A;  3MIT A;  4R6R A;  2BMZ A;  2GUE A;  2GUC A;  3P8S A;  3VY7 A;  1ZGS A;  5J51 A;  4AKC A;  1XEZ A;  4R6P A;  1J4U A;  3LL0 A;  3R51 A;  1TOQ A;  3WOC A;  4DDN A;  1VBO A;  3MIV A;  4PIF A;  1KU8 A;  2NU5 A;  2GUD A;  1TP8 A;  1M26 A;  3O44 A;  1JAC A;  4MQ0 A;  5J4T A;  1C3K A;  4PIU A;  1UH0 A;  1C3M A; 
#chains in the Genus database with same CATH topology
 4QX3 A;  2GUX A;  4R6Q A;  5BN6 E;  1UGX A;  3MIU A;  4QX1 A;  1XXR A;  1I5P A;  1XXQ A;  4R6N A;  3LL1 A;  1J4T A;  2BN0 A;  1ZGR A;  3AQG A;  4AK4 A;  3R50 A;  3R52 A;  1KUJ A;  1PXD A;  3TOW A;  1WS5 C;  1WS4 C;  4R6O A;  5JM1 A;  1WS5 A;  1WS4 A;  3VY6 A;  4D8M A;  3LKY A;  3VZG A;  3APA A;  3LM1 A;  1OUW A;  2BMY A;  4PIT A;  5EXG A;  4W8J A;  5AV7 A;  3VZE A;  1VBP A;  1CIY A;  2HYQ A;  5J4X A;  1X1V A;  1J4S A;  4AKB A;  3LLY A;  3WOB A;  1UGW C;  2NUO A;  4AKD A;  1UGW A;  3LL2 A;  1VMO A;  2JZ4 A;  4PIK A;  1UH1 A;  4WOG A;  5J50 A;  4QX2 A;  1UGY C;  1C3N A;  2GTY A;  3LLZ A;  1UGY A;  4GX7 A;  1JOT A;  4MOA A;  2HYR A;  3VZF A;  4QX0 A;  3MIT A;  4R6R A;  1DLC A;  4ARX A;  2BMZ A;  2GUE A;  2GUC A;  3P8S A;  3VY7 A;  1ZGS A;  1W99 A;  5J51 A;  4AKC A;  1XEZ A;  4R6P A;  1J4U A;  3LL0 A;  3R51 A;  3EB7 A;  1TOQ A;  3WOC A;  2QP2 A;  4DDN A;  1VBO A;  3MIV A;  4PIF A;  1KU8 A;  2NU5 A;  2GUD A;  1TP8 A;  1M26 A;  3O44 A;  1JI6 A;  1JAC A;  2C9K A;  4MQ0 A;  4ARY A;  5J4T A;  1C3K A;  4PIU A;  1UH0 A;  1C3M A; 
#chains in the Genus database with same CATH homology
 2GUX A;  4R6Q A;  5BN6 E;  1UGX A;  3MIU A;  1XXR A;  1XXQ A;  4R6N A;  3LL1 A;  1J4T A;  2BN0 A;  1ZGR A;  3AQG A;  4AK4 A;  3R50 A;  3R52 A;  1KUJ A;  1PXD A;  1WS5 C;  1WS4 C;  4R6O A;  5JM1 A;  1WS5 A;  1WS4 A;  3VY6 A;  3LKY A;  3VZG A;  3APA A;  3LM1 A;  1OUW A;  2BMY A;  4PIT A;  5EXG A;  5AV7 A;  3VZE A;  1VBP A;  2HYQ A;  5J4X A;  1X1V A;  1J4S A;  4AKB A;  3LLY A;  3WOB A;  1UGW C;  2NUO A;  4AKD A;  1UGW A;  3LL2 A;  2JZ4 A;  4PIK A;  1UH1 A;  4WOG A;  5J50 A;  1UGY C;  1C3N A;  2GTY A;  3LLZ A;  1UGY A;  4GX7 A;  1JOT A;  2HYR A;  3VZF A;  3MIT A;  4R6R A;  2BMZ A;  2GUE A;  2GUC A;  3P8S A;  3VY7 A;  1ZGS A;  5J51 A;  4AKC A;  1XEZ A;  4R6P A;  1J4U A;  3LL0 A;  3R51 A;  1TOQ A;  3WOC A;  4DDN A;  1VBO A;  3MIV A;  4PIF A;  1KU8 A;  2NU5 A;  2GUD A;  1TP8 A;  1M26 A;  3O44 A;  1JAC A;  4MQ0 A;  5J4T A;  1C3K A;  4PIU A;  1UH0 A;  1C3M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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