2ISKA

Blub bound to flavin anion (charge transfer complex)
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
219
structure length
219
Chain Sequence
LTAAGAFSSDERAAVYRAIETRRDVRDEFLPEPLSEELIARLLGAAHQAPSVGFMQPWNFVLVRQDETREKVWQAFQRANDEAAEMFSGERQAKYRSLKLEGIRKAPLSICVTCDRTRGGAVVLGRTHNPQMDLYSTVCAVQNLWLAARAEGVGVGWVSIFHESEIKAILGIPDHVEIVAWLCLGFVDRLYQEPELAAKGWRQRLPLEDLVFEEGWGVR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title BluB cannibalizes flavin to form the lower ligand of vitamin B12.
pubmed doi rcsb
molecule tags Flavoprotein
source organism Sinorhizobium meliloti
molecule keywords BluB
total genus 66
structure length 219
sequence length 219
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 1.13.11.79: 5,6-dimethylbenzimidazole synthase.
pdb deposition date 2006-10-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00881 Nitroreductase Nitroreductase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.109.10 Alpha Beta 3-Layer(aba) Sandwich NADH Oxidase NADH Oxidase 2iskA01
1BKJA 3BM1A 4DN2A 3E10A 1YLUA 2ISLA 2I7HA 1YWQA 3KWKA 5KO7A 4XOOA 1V5ZA 1ZCHA 1KQCA 3GH8A 1OO5A 3OF4A 3GE5A 3GBHA 3HZNA 1KQBA 3GR3A 2B67A 4EO3A 3E39A 3QDLA 3EO7A 1OOQA 1VKWA 1DS7A 1NOXA 1YKIA 4QLYA 3BEMA 4BN6A 3M5KA 1ICVA 1YLRA 2FREA 1ICUA 4QLXA 2ISKA 2WQFA 2YMVA 1ICRA 3EO8A 3HOIA 4TTBA 5HEIA 4BN9A 3N2SA 4G8SA 2R01A 1KQDA 4BNBA 4XOMA 1V5YA 3GB5A 2HAYA 4BN8A 3PXVA 3X21A 5J6CA 1VFRA 4TTCA 3EK3A 1IDTA 2WZWA 1F5VA 5KO8A 3X22A 3TO0A 1OONA 3H4OA 4XOQA 1OO6A 1NECA 3TNZA 4URPA 3GFDA 3G14A 3K6HA 4BN7A 3EOFA 2IFAA 2WZVA 2H0UA 3HJ9A 2ISJA 2BKJA 3GE6A 3KOQA 3GFAA 3BM2A 5HDJA 3GAGA 5KRDA
chains in the Genus database with same CATH superfamily
1BKJA 3BM1A 4DN2A 3E10A 1YLUA 2ISLA 2I7HA 1YWQA 3KWKA 5KO7A 4XOOA 1V5ZA 1ZCHA 1KQCA 3GH8A 1OO5A 3OF4A 3GE5A 3GBHA 3HZNA 1KQBA 3GR3A 2B67A 4EO3A 3E39A 3QDLA 3EO7A 1OOQA 1VKWA 1DS7A 1NOXA 1YKIA 4QLYA 3BEMA 4BN6A 3M5KA 1ICVA 1YLRA 2FREA 1ICUA 4QLXA 2ISKA 2WQFA 2YMVA 1ICRA 3EO8A 3HOIA 4TTBA 5HEIA 4BN9A 3N2SA 4G8SA 2R01A 1KQDA 4BNBA 4XOMA 1V5YA 3GB5A 2HAYA 4BN8A 3PXVA 3X21A 5J6CA 1VFRA 4TTCA 3EK3A 1IDTA 2WZWA 1F5VA 5KO8A 3X22A 3TO0A 1OONA 3H4OA 4XOQA 1OO6A 1NECA 1J6RA 3TNZA 4URPA 3GFDA 3G14A 3K6HA 4BN7A 3EOFA 2IFAA 2WZVA 2H0UA 3HJ9A 2ISJA 2BKJA 3GE6A 3KOQA 3GFAA 3BM2A 5HDJA 3GAGA 5KRDA
chains in the Genus database with same CATH topology
1BKJA 3BM1A 4DN2A 3E10A 1YLUA 2ISLA 2I7HA 1YWQA 3KWKA 5KO7A 4XOOA 1V5ZA 1ZCHA 1KQCA 3GH8A 1OO5A 3OF4A 3GE5A 3GBHA 3HZNA 1KQBA 3GR3A 2B67A 4EO3A 3E39A 3QDLA 3EO7A 1OOQA 1VKWA 1DS7A 1NOXA 1YKIA 4QLYA 3BEMA 4BN6A 3M5KA 1ICVA 1YLRA 2FREA 1ICUA 4QLXA 2ISKA 2WQFA 2YMVA 1ICRA 3EO8A 3HOIA 4TTBA 5HEIA 4BN9A 3N2SA 4G8SA 2R01A 1KQDA 4BNBA 4XOMA 1V5YA 3GB5A 2HAYA 4BN8A 3PXVA 3X21A 5J6CA 1VFRA 4TTCA 3EK3A 1IDTA 2WZWA 1F5VA 5KO8A 3X22A 3TO0A 1OONA 3H4OA 4XOQA 1OO6A 1NECA 1J6RA 3TNZA 4URPA 3GFDA 3G14A 3K6HA 4BN7A 3EOFA 2IFAA 2WZVA 2H0UA 3HJ9A 2ISJA 2BKJA 3GE6A 3KOQA 3GFAA 3BM2A 5HDJA 3GAGA 5KRDA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1BKJ A;  3BM1 A;  4DN2 A;  3E10 A;  1YLU A;  2ISL A;  2I7H A;  1YWQ A;  3KWK A;  5KO7 A;  4XOO A;  1V5Z A;  1ZCH A;  1KQC A;  3GH8 A;  1OO5 A;  3OF4 A;  3GE5 A;  3GBH A;  3HZN A;  1KQB A;  3GR3 A;  2B67 A;  4EO3 A;  3E39 A;  3QDL A;  3EO7 A;  1OOQ A;  1VKW A;  1DS7 A;  1NOX A;  1YKI A;  4QLY A;  3BEM A;  4BN6 A;  3M5K A;  1ICV A;  1YLR A;  2FRE A;  1ICU A;  4QLX A;  2ISK A;  2WQF A;  2YMV A;  1ICR A;  3EO8 A;  3HOI A;  4TTB A;  5HEI A;  4BN9 A;  3N2S A;  4G8S A;  2R01 A;  1KQD A;  4BNB A;  4XOM A;  1V5Y A;  3GB5 A;  2HAY A;  4BN8 A;  3PXV A;  3X21 A;  5J6C A;  1VFR A;  4TTC A;  3EK3 A;  1IDT A;  2WZW A;  1F5V A;  5KO8 A;  3X22 A;  3TO0 A;  1OON A;  3H4O A;  4XOQ A;  1OO6 A;  1NEC A;  3TNZ A;  4URP A;  3GFD A;  3G14 A;  3K6H A;  4BN7 A;  3EOF A;  2IFA A;  2WZV A;  2H0U A;  3HJ9 A;  2ISJ A;  2BKJ A;  3GE6 A;  3KOQ A;  3GFA A;  3BM2 A;  5HDJ A;  3GAG A;  5KRD A; 
#chains in the Genus database with same CATH topology
 1BKJ A;  3BM1 A;  4DN2 A;  3E10 A;  1YLU A;  2ISL A;  2I7H A;  1YWQ A;  3KWK A;  5KO7 A;  4XOO A;  1V5Z A;  1ZCH A;  1KQC A;  3GH8 A;  1OO5 A;  3OF4 A;  3GE5 A;  3GBH A;  3HZN A;  1KQB A;  3GR3 A;  2B67 A;  4EO3 A;  3E39 A;  3QDL A;  3EO7 A;  1OOQ A;  1VKW A;  1DS7 A;  1NOX A;  1YKI A;  4QLY A;  3BEM A;  4BN6 A;  3M5K A;  1ICV A;  1YLR A;  2FRE A;  1ICU A;  4QLX A;  2ISK A;  2WQF A;  2YMV A;  1ICR A;  3EO8 A;  3HOI A;  4TTB A;  5HEI A;  4BN9 A;  3N2S A;  4G8S A;  2R01 A;  1KQD A;  4BNB A;  4XOM A;  1V5Y A;  3GB5 A;  2HAY A;  4BN8 A;  3PXV A;  3X21 A;  5J6C A;  1VFR A;  4TTC A;  3EK3 A;  1IDT A;  2WZW A;  1F5V A;  5KO8 A;  3X22 A;  3TO0 A;  1OON A;  3H4O A;  4XOQ A;  1OO6 A;  1NEC A;  1J6R A;  3TNZ A;  4URP A;  3GFD A;  3G14 A;  3K6H A;  4BN7 A;  3EOF A;  2IFA A;  2WZV A;  2H0U A;  3HJ9 A;  2ISJ A;  2BKJ A;  3GE6 A;  3KOQ A;  3GFA A;  3BM2 A;  5HDJ A;  3GAG A;  5KRD A; 
#chains in the Genus database with same CATH homology
 1BKJ A;  3BM1 A;  4DN2 A;  3E10 A;  1YLU A;  2ISL A;  2I7H A;  1YWQ A;  3KWK A;  5KO7 A;  4XOO A;  1V5Z A;  1ZCH A;  1KQC A;  3GH8 A;  1OO5 A;  3OF4 A;  3GE5 A;  3GBH A;  3HZN A;  1KQB A;  3GR3 A;  2B67 A;  4EO3 A;  3E39 A;  3QDL A;  3EO7 A;  1OOQ A;  1VKW A;  1DS7 A;  1NOX A;  1YKI A;  4QLY A;  3BEM A;  4BN6 A;  3M5K A;  1ICV A;  1YLR A;  2FRE A;  1ICU A;  4QLX A;  2ISK A;  2WQF A;  2YMV A;  1ICR A;  3EO8 A;  3HOI A;  4TTB A;  5HEI A;  4BN9 A;  3N2S A;  4G8S A;  2R01 A;  1KQD A;  4BNB A;  4XOM A;  1V5Y A;  3GB5 A;  2HAY A;  4BN8 A;  3PXV A;  3X21 A;  5J6C A;  1VFR A;  4TTC A;  3EK3 A;  1IDT A;  2WZW A;  1F5V A;  5KO8 A;  3X22 A;  3TO0 A;  1OON A;  3H4O A;  4XOQ A;  1OO6 A;  1NEC A;  1J6R A;  3TNZ A;  4URP A;  3GFD A;  3G14 A;  3K6H A;  4BN7 A;  3EOF A;  2IFA A;  2WZV A;  2H0U A;  3HJ9 A;  2ISJ A;  2BKJ A;  3GE6 A;  3KOQ A;  3GFA A;  3BM2 A;  5HDJ A;  3GAG A;  5KRD A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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