2ISKA

Blub bound to flavin anion (charge transfer complex)
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
219
structure length
219
Chain Sequence
LTAAGAFSSDERAAVYRAIETRRDVRDEFLPEPLSEELIARLLGAAHQAPSVGFMQPWNFVLVRQDETREKVWQAFQRANDEAAEMFSGERQAKYRSLKLEGIRKAPLSICVTCDRTRGGAVVLGRTHNPQMDLYSTVCAVQNLWLAARAEGVGVGWVSIFHESEIKAILGIPDHVEIVAWLCLGFVDRLYQEPELAAKGWRQRLPLEDLVFEEGWGVR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title BluB cannibalizes flavin to form the lower ligand of vitamin B12.
pubmed doi rcsb
molecule tags Flavoprotein
source organism Sinorhizobium meliloti
molecule keywords BluB
total genus 66
structure length 219
sequence length 219
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 1.13.11.79: 5,6-dimethylbenzimidazole synthase.
pdb deposition date 2006-10-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00881 Nitroreductase Nitroreductase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.109.10 Alpha Beta 3-Layer(aba) Sandwich NADH Oxidase NADH Oxidase 2iskA01
4BN7A 1NOXA 1V5ZA 2HAYA 3HZNA 3EOFA 1ICRA 1IDTA 3HOIA 4URPA 4TTCA 2ISLA 2YMVA 3GE5A 1ZCHA 4QLYA 2B67A 2IFAA 2WZWA 3GR3A 4TTBA 4BN6A 3BEMA 3X22A 5HDJA 5KO8A 3E39A 1YLUA 3H4OA 5KRDA 1KQBA 3KWKA 3KOQA 3X21A 2ISKA 1YLRA 3GE6A 1YWQA 3N2SA 3BM2A 3TO0A 1NECA 3TNZA 1ICUA 4G8SA 1OO5A 1DS7A 1VFRA 4XOQA 3QDLA 1KQDA 3G14A 3GAGA 4EO3A 4BNBA 1KQCA 2BKJA 1VKWA 1OO6A 3PXVA 3EO7A 1OONA 3GBHA 4QLXA 1F5VA 5J6CA 3EK3A 2FREA 2R01A 2H0UA 3GH8A 1V5YA 2ISJA 3HJ9A 3E10A 4BN8A 1OOQA 3OF4A 2WQFA 5KO7A 3BM1A 5HEIA 3K6HA 3GFAA 4BN9A 1YKIA 1BKJA 3GFDA 1ICVA 4XOMA 3M5KA 4XOOA 2I7HA 3GB5A 4DN2A 3EO8A 2WZVA
chains in the Genus database with same CATH superfamily
4BN7A 1NOXA 1V5ZA 2HAYA 3HZNA 3EOFA 1ICRA 1IDTA 3HOIA 4URPA 4TTCA 2ISLA 2YMVA 3GE5A 1ZCHA 4QLYA 2B67A 2IFAA 2WZWA 3GR3A 4TTBA 4BN6A 3BEMA 3X22A 5HDJA 5KO8A 3E39A 1YLUA 3H4OA 5KRDA 1KQBA 3KWKA 3KOQA 3X21A 2ISKA 1YLRA 3GE6A 1YWQA 3N2SA 3BM2A 3TO0A 1NECA 3TNZA 1ICUA 4G8SA 1OO5A 1DS7A 1VFRA 4XOQA 3QDLA 1KQDA 3G14A 3GAGA 4EO3A 4BNBA 1KQCA 2BKJA 1VKWA 1OO6A 3PXVA 3EO7A 1OONA 3GBHA 4QLXA 1F5VA 5J6CA 3EK3A 2FREA 2R01A 2H0UA 3GH8A 1V5YA 2ISJA 3HJ9A 3E10A 4BN8A 1OOQA 3OF4A 2WQFA 5KO7A 1J6RA 3BM1A 5HEIA 3K6HA 3GFAA 4BN9A 1YKIA 1BKJA 3GFDA 1ICVA 4XOMA 3M5KA 4XOOA 2I7HA 3GB5A 4DN2A 3EO8A 2WZVA
chains in the Genus database with same CATH topology
4BN7A 1NOXA 1V5ZA 2HAYA 3HZNA 3EOFA 1ICRA 1IDTA 3HOIA 4URPA 4TTCA 2ISLA 2YMVA 3GE5A 1ZCHA 4QLYA 2B67A 2IFAA 2WZWA 3GR3A 4TTBA 4BN6A 3BEMA 3X22A 5HDJA 5KO8A 3E39A 1YLUA 3H4OA 5KRDA 1KQBA 3KWKA 3KOQA 3X21A 2ISKA 1YLRA 3GE6A 1YWQA 3N2SA 3BM2A 3TO0A 1NECA 3TNZA 1ICUA 4G8SA 1OO5A 1DS7A 1VFRA 4XOQA 3QDLA 1KQDA 3G14A 3GAGA 4EO3A 4BNBA 1KQCA 2BKJA 1VKWA 1OO6A 3PXVA 3EO7A 1OONA 3GBHA 4QLXA 1F5VA 5J6CA 3EK3A 2FREA 2R01A 2H0UA 3GH8A 1V5YA 2ISJA 3HJ9A 3E10A 4BN8A 1OOQA 3OF4A 2WQFA 5KO7A 1J6RA 3BM1A 5HEIA 3K6HA 3GFAA 4BN9A 1YKIA 1BKJA 3GFDA 1ICVA 4XOMA 3M5KA 4XOOA 2I7HA 3GB5A 4DN2A 3EO8A 2WZVA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4BN7 A;  1NOX A;  1V5Z A;  2HAY A;  3HZN A;  3EOF A;  1ICR A;  1IDT A;  3HOI A;  4URP A;  4TTC A;  2ISL A;  2YMV A;  3GE5 A;  1ZCH A;  4QLY A;  2B67 A;  2IFA A;  2WZW A;  3GR3 A;  4TTB A;  4BN6 A;  3BEM A;  3X22 A;  5HDJ A;  5KO8 A;  3E39 A;  1YLU A;  3H4O A;  5KRD A;  1KQB A;  3KWK A;  3KOQ A;  3X21 A;  2ISK A;  1YLR A;  3GE6 A;  1YWQ A;  3N2S A;  3BM2 A;  3TO0 A;  1NEC A;  3TNZ A;  1ICU A;  4G8S A;  1OO5 A;  1DS7 A;  1VFR A;  4XOQ A;  3QDL A;  1KQD A;  3G14 A;  3GAG A;  4EO3 A;  4BNB A;  1KQC A;  2BKJ A;  1VKW A;  1OO6 A;  3PXV A;  3EO7 A;  1OON A;  3GBH A;  4QLX A;  1F5V A;  5J6C A;  3EK3 A;  2FRE A;  2R01 A;  2H0U A;  3GH8 A;  1V5Y A;  2ISJ A;  3HJ9 A;  3E10 A;  4BN8 A;  1OOQ A;  3OF4 A;  2WQF A;  5KO7 A;  3BM1 A;  5HEI A;  3K6H A;  3GFA A;  4BN9 A;  1YKI A;  1BKJ A;  3GFD A;  1ICV A;  4XOM A;  3M5K A;  4XOO A;  2I7H A;  3GB5 A;  4DN2 A;  3EO8 A;  2WZV A; 
#chains in the Genus database with same CATH topology
 4BN7 A;  1NOX A;  1V5Z A;  2HAY A;  3HZN A;  3EOF A;  1ICR A;  1IDT A;  3HOI A;  4URP A;  4TTC A;  2ISL A;  2YMV A;  3GE5 A;  1ZCH A;  4QLY A;  2B67 A;  2IFA A;  2WZW A;  3GR3 A;  4TTB A;  4BN6 A;  3BEM A;  3X22 A;  5HDJ A;  5KO8 A;  3E39 A;  1YLU A;  3H4O A;  5KRD A;  1KQB A;  3KWK A;  3KOQ A;  3X21 A;  2ISK A;  1YLR A;  3GE6 A;  1YWQ A;  3N2S A;  3BM2 A;  3TO0 A;  1NEC A;  3TNZ A;  1ICU A;  4G8S A;  1OO5 A;  1DS7 A;  1VFR A;  4XOQ A;  3QDL A;  1KQD A;  3G14 A;  3GAG A;  4EO3 A;  4BNB A;  1KQC A;  2BKJ A;  1VKW A;  1OO6 A;  3PXV A;  3EO7 A;  1OON A;  3GBH A;  4QLX A;  1F5V A;  5J6C A;  3EK3 A;  2FRE A;  2R01 A;  2H0U A;  3GH8 A;  1V5Y A;  2ISJ A;  3HJ9 A;  3E10 A;  4BN8 A;  1OOQ A;  3OF4 A;  2WQF A;  5KO7 A;  1J6R A;  3BM1 A;  5HEI A;  3K6H A;  3GFA A;  4BN9 A;  1YKI A;  1BKJ A;  3GFD A;  1ICV A;  4XOM A;  3M5K A;  4XOO A;  2I7H A;  3GB5 A;  4DN2 A;  3EO8 A;  2WZV A; 
#chains in the Genus database with same CATH homology
 4BN7 A;  1NOX A;  1V5Z A;  2HAY A;  3HZN A;  3EOF A;  1ICR A;  1IDT A;  3HOI A;  4URP A;  4TTC A;  2ISL A;  2YMV A;  3GE5 A;  1ZCH A;  4QLY A;  2B67 A;  2IFA A;  2WZW A;  3GR3 A;  4TTB A;  4BN6 A;  3BEM A;  3X22 A;  5HDJ A;  5KO8 A;  3E39 A;  1YLU A;  3H4O A;  5KRD A;  1KQB A;  3KWK A;  3KOQ A;  3X21 A;  2ISK A;  1YLR A;  3GE6 A;  1YWQ A;  3N2S A;  3BM2 A;  3TO0 A;  1NEC A;  3TNZ A;  1ICU A;  4G8S A;  1OO5 A;  1DS7 A;  1VFR A;  4XOQ A;  3QDL A;  1KQD A;  3G14 A;  3GAG A;  4EO3 A;  4BNB A;  1KQC A;  2BKJ A;  1VKW A;  1OO6 A;  3PXV A;  3EO7 A;  1OON A;  3GBH A;  4QLX A;  1F5V A;  5J6C A;  3EK3 A;  2FRE A;  2R01 A;  2H0U A;  3GH8 A;  1V5Y A;  2ISJ A;  3HJ9 A;  3E10 A;  4BN8 A;  1OOQ A;  3OF4 A;  2WQF A;  5KO7 A;  1J6R A;  3BM1 A;  5HEI A;  3K6H A;  3GFA A;  4BN9 A;  1YKI A;  1BKJ A;  3GFD A;  1ICV A;  4XOM A;  3M5K A;  4XOO A;  2I7H A;  3GB5 A;  4DN2 A;  3EO8 A;  2WZV A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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