2ISLA

Blub bound to reduced flavin (fmnh2) and molecular oxygen. (clear crystal form)
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
219
structure length
219
Chain Sequence
LTAAGAFSSDERAAVYRAIETRRDVRDEFLPEPLSEELIARLLGAAHQAPSVGFMQPWNFVLVRQDETREKVWQAFQRANDEAAEMFSGERQAKYRSLKLEGIRKAPLSICVTCDRTRGGAVVLGRTHNPQMDLYSTVCAVQNLWLAARAEGVGVGWVSIFHESEIKAILGIPDHVEIVAWLCLGFVDRLYQEPELAAKGWRQRLPLEDLVFEEGWGVR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title BluB cannibalizes flavin to form the lower ligand of vitamin B12.
pubmed doi rcsb
molecule tags Flavoprotein
source organism Sinorhizobium meliloti
molecule keywords BluB
total genus 62
structure length 219
sequence length 219
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 1.13.11.79: 5,6-dimethylbenzimidazole synthase.
pdb deposition date 2006-10-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00881 Nitroreductase Nitroreductase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.109.10 Alpha Beta 3-Layer(aba) Sandwich NADH Oxidase NADH Oxidase 2islA01
3QDLA 1ICUA 2BKJA 5J6CA 1YKIA 3N2SA 3GE6A 2I7HA 4BN7A 2ISKA 4XOOA 2HAYA 1VKWA 4BN8A 3H4OA 1OO6A 1OOQA 3BM2A 4QLYA 1NECA 3TO0A 2H0UA 1IDTA 3EK3A 3GH8A 2R01A 1KQBA 2WQFA 5KO7A 3EOFA 3HOIA 2WZVA 3E10A 1YLRA 3X21A 3EO8A 4XOMA 4EO3A 4BN9A 5KO8A 3M5KA 5KRDA 3HZNA 1ICVA 3GR3A 3OF4A 3G14A 3GBHA 1NOXA 2ISLA 4TTCA 3GE5A 3GFAA 1DS7A 3KWKA 2WZWA 1YWQA 4DN2A 1YLUA 4G8SA 3KOQA 1V5ZA 4URPA 2B67A 3X22A 3GB5A 4BN6A 4QLXA 1KQCA 1OONA 1ZCHA 1BKJA 1OO5A 3GAGA 1V5YA 3HJ9A 3PXVA 1F5VA 1KQDA 2IFAA 3GFDA 2FREA 4XOQA 5HEIA 3E39A 3K6HA 3BEMA 2YMVA 2ISJA 1ICRA 1VFRA 4TTBA 4BNBA 3BM1A 3EO7A 3TNZA 5HDJA
chains in the Genus database with same CATH superfamily
3QDLA 1ICUA 2BKJA 5J6CA 1YKIA 3N2SA 3GE6A 2I7HA 4BN7A 2ISKA 4XOOA 2HAYA 1VKWA 4BN8A 3H4OA 1OO6A 1OOQA 3BM2A 4QLYA 1NECA 3TO0A 2H0UA 1IDTA 3EK3A 3GH8A 2R01A 1KQBA 2WQFA 5KO7A 3EOFA 3HOIA 2WZVA 3E10A 1YLRA 3X21A 3EO8A 4XOMA 4EO3A 4BN9A 5KO8A 3M5KA 5KRDA 3HZNA 1ICVA 3GR3A 3OF4A 3G14A 3GBHA 1NOXA 2ISLA 4TTCA 3GE5A 3GFAA 1J6RA 1DS7A 3KWKA 2WZWA 1YWQA 4DN2A 1YLUA 4G8SA 3KOQA 1V5ZA 4URPA 2B67A 3X22A 3GB5A 4BN6A 4QLXA 1KQCA 1OONA 1ZCHA 1BKJA 1OO5A 3GAGA 1V5YA 3HJ9A 3PXVA 1F5VA 1KQDA 2IFAA 3GFDA 2FREA 4XOQA 5HEIA 3E39A 3K6HA 3BEMA 2YMVA 2ISJA 1ICRA 1VFRA 4TTBA 4BNBA 3BM1A 3EO7A 3TNZA 5HDJA
chains in the Genus database with same CATH topology
3QDLA 1ICUA 2BKJA 5J6CA 1YKIA 3N2SA 3GE6A 2I7HA 4BN7A 2ISKA 4XOOA 2HAYA 1VKWA 4BN8A 3H4OA 1OO6A 1OOQA 3BM2A 4QLYA 1NECA 3TO0A 2H0UA 1IDTA 3EK3A 3GH8A 2R01A 1KQBA 2WQFA 5KO7A 3EOFA 3HOIA 2WZVA 3E10A 1YLRA 3X21A 3EO8A 4XOMA 4EO3A 4BN9A 5KO8A 3M5KA 5KRDA 3HZNA 1ICVA 3GR3A 3OF4A 3G14A 3GBHA 1NOXA 2ISLA 4TTCA 3GE5A 3GFAA 1J6RA 1DS7A 3KWKA 2WZWA 1YWQA 4DN2A 1YLUA 4G8SA 3KOQA 1V5ZA 4URPA 2B67A 3X22A 3GB5A 4BN6A 4QLXA 1KQCA 1OONA 1ZCHA 1BKJA 1OO5A 3GAGA 1V5YA 3HJ9A 3PXVA 1F5VA 1KQDA 2IFAA 3GFDA 2FREA 4XOQA 5HEIA 3E39A 3K6HA 3BEMA 2YMVA 2ISJA 1ICRA 1VFRA 4TTBA 4BNBA 3BM1A 3EO7A 3TNZA 5HDJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QDL A;  1ICU A;  2BKJ A;  5J6C A;  1YKI A;  3N2S A;  3GE6 A;  2I7H A;  4BN7 A;  2ISK A;  4XOO A;  2HAY A;  1VKW A;  4BN8 A;  3H4O A;  1OO6 A;  1OOQ A;  3BM2 A;  4QLY A;  1NEC A;  3TO0 A;  2H0U A;  1IDT A;  3EK3 A;  3GH8 A;  2R01 A;  1KQB A;  2WQF A;  5KO7 A;  3EOF A;  3HOI A;  2WZV A;  3E10 A;  1YLR A;  3X21 A;  3EO8 A;  4XOM A;  4EO3 A;  4BN9 A;  5KO8 A;  3M5K A;  5KRD A;  3HZN A;  1ICV A;  3GR3 A;  3OF4 A;  3G14 A;  3GBH A;  1NOX A;  2ISL A;  4TTC A;  3GE5 A;  3GFA A;  1DS7 A;  3KWK A;  2WZW A;  1YWQ A;  4DN2 A;  1YLU A;  4G8S A;  3KOQ A;  1V5Z A;  4URP A;  2B67 A;  3X22 A;  3GB5 A;  4BN6 A;  4QLX A;  1KQC A;  1OON A;  1ZCH A;  1BKJ A;  1OO5 A;  3GAG A;  1V5Y A;  3HJ9 A;  3PXV A;  1F5V A;  1KQD A;  2IFA A;  3GFD A;  2FRE A;  4XOQ A;  5HEI A;  3E39 A;  3K6H A;  3BEM A;  2YMV A;  2ISJ A;  1ICR A;  1VFR A;  4TTB A;  4BNB A;  3BM1 A;  3EO7 A;  3TNZ A;  5HDJ A; 
#chains in the Genus database with same CATH topology
 3QDL A;  1ICU A;  2BKJ A;  5J6C A;  1YKI A;  3N2S A;  3GE6 A;  2I7H A;  4BN7 A;  2ISK A;  4XOO A;  2HAY A;  1VKW A;  4BN8 A;  3H4O A;  1OO6 A;  1OOQ A;  3BM2 A;  4QLY A;  1NEC A;  3TO0 A;  2H0U A;  1IDT A;  3EK3 A;  3GH8 A;  2R01 A;  1KQB A;  2WQF A;  5KO7 A;  3EOF A;  3HOI A;  2WZV A;  3E10 A;  1YLR A;  3X21 A;  3EO8 A;  4XOM A;  4EO3 A;  4BN9 A;  5KO8 A;  3M5K A;  5KRD A;  3HZN A;  1ICV A;  3GR3 A;  3OF4 A;  3G14 A;  3GBH A;  1NOX A;  2ISL A;  4TTC A;  3GE5 A;  3GFA A;  1J6R A;  1DS7 A;  3KWK A;  2WZW A;  1YWQ A;  4DN2 A;  1YLU A;  4G8S A;  3KOQ A;  1V5Z A;  4URP A;  2B67 A;  3X22 A;  3GB5 A;  4BN6 A;  4QLX A;  1KQC A;  1OON A;  1ZCH A;  1BKJ A;  1OO5 A;  3GAG A;  1V5Y A;  3HJ9 A;  3PXV A;  1F5V A;  1KQD A;  2IFA A;  3GFD A;  2FRE A;  4XOQ A;  5HEI A;  3E39 A;  3K6H A;  3BEM A;  2YMV A;  2ISJ A;  1ICR A;  1VFR A;  4TTB A;  4BNB A;  3BM1 A;  3EO7 A;  3TNZ A;  5HDJ A; 
#chains in the Genus database with same CATH homology
 3QDL A;  1ICU A;  2BKJ A;  5J6C A;  1YKI A;  3N2S A;  3GE6 A;  2I7H A;  4BN7 A;  2ISK A;  4XOO A;  2HAY A;  1VKW A;  4BN8 A;  3H4O A;  1OO6 A;  1OOQ A;  3BM2 A;  4QLY A;  1NEC A;  3TO0 A;  2H0U A;  1IDT A;  3EK3 A;  3GH8 A;  2R01 A;  1KQB A;  2WQF A;  5KO7 A;  3EOF A;  3HOI A;  2WZV A;  3E10 A;  1YLR A;  3X21 A;  3EO8 A;  4XOM A;  4EO3 A;  4BN9 A;  5KO8 A;  3M5K A;  5KRD A;  3HZN A;  1ICV A;  3GR3 A;  3OF4 A;  3G14 A;  3GBH A;  1NOX A;  2ISL A;  4TTC A;  3GE5 A;  3GFA A;  1J6R A;  1DS7 A;  3KWK A;  2WZW A;  1YWQ A;  4DN2 A;  1YLU A;  4G8S A;  3KOQ A;  1V5Z A;  4URP A;  2B67 A;  3X22 A;  3GB5 A;  4BN6 A;  4QLX A;  1KQC A;  1OON A;  1ZCH A;  1BKJ A;  1OO5 A;  3GAG A;  1V5Y A;  3HJ9 A;  3PXV A;  1F5V A;  1KQD A;  2IFA A;  3GFD A;  2FRE A;  4XOQ A;  5HEI A;  3E39 A;  3K6H A;  3BEM A;  2YMV A;  2ISJ A;  1ICR A;  1VFR A;  4TTB A;  4BNB A;  3BM1 A;  3EO7 A;  3TNZ A;  5HDJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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