2LFHA

Solution nmr structure of the helix-loop-helix domain of human id3 protein, northeast structural genomics consortium target hr3111a
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
68
structure length
68
Chain Sequence
MGHHHHHHSHMGGGKGPAAEEPLSLLDDMNHCYSRLRELVPGVPRGTQLSQVEILQRVIDYILDLQVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution NMR Structure of the Helix-loop-Helix Domain of Human ID3 Protein, Northeast Structural Genomics Consortium Target HR3111A
rcsb
molecule keywords DNA-binding protein inhibitor ID-3
molecule tags Dna binding protein inhibitor
source organism Homo sapiens
total genus 11
structure length 68
sequence length 68
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 2lfhA00
1NLWB 2YPBB 1AM9A 1HLOA 1AN2A 4ATIA 5I50A 4F3LB 2QL2B 5I4ZA 1MDYA 1NKPB 1MDYB 2YPAA 4H10A 2LFHA 1NLWA 2YPBA 3MUJA 4ATKA 4ATHA 1A0AA 1UKLC 4F3LA 2QL2A 1AN4A 4AYAA 2MH3A 3U5VA 1R05A 5EYOA 2YPAB 4H10B 1NKPA
chains in the Genus database with same CATH superfamily
1NLWB 2YPBB 1AM9A 1HLOA 1AN2A 4ATIA 5I50A 4F3LB 2QL2B 1K1FA 5I4ZA 1MDYA 1NKPB 1MDYB 2YPAA 4H10A 2LFHA 1NLWA 2YPBA 3MUJA 4ATKA 4ATHA 1A0AA 1UKLC 4F3LA 2QL2A 1AN4A 4AYAA 1ZZAA 2MH3A 3U5VA 1R05A 5EYOA 2YPAB 4H10B 1NKPA
chains in the Genus database with same CATH topology
1NLWB 2YPBB 1AM9A 1HLOA 1AN2A 4ATIA 5I50A 4F3LB 2QL2B 5I4ZA 1MDYA 1NKPB 1MDYB 2YPAA 4H10A 2LFHA 1NLWA 2YPBA 3MUJA 4ATKA 4ATHA 1A0AA 1UKLC 4F3LA 2QL2A 1AN4A 4AYAA 2MH3A 3U5VA 1R05A 5EYOA 2YPAB 4H10B 1NKPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NLW B;  2YPB B;  1AM9 A;  1HLO A;  1AN2 A;  4ATI A;  5I50 A;  4F3L B;  2QL2 B;  5I4Z A;  1MDY A;  1NKP B;  1MDY B;  2YPA A;  4H10 A;  2LFH A;  1NLW A;  2YPB A;  3MUJ A;  4ATK A;  4ATH A;  1A0A A;  1UKL C;  4F3L A;  2QL2 A;  1AN4 A;  4AYA A;  2MH3 A;  3U5V A;  1R05 A;  5EYO A;  2YPA B;  4H10 B;  1NKP A; 
#chains in the Genus database with same CATH topology
 1NLW B;  2YPB B;  1AM9 A;  1HLO A;  1AN2 A;  4ATI A;  5I50 A;  4F3L B;  2QL2 B;  1K1F A;  5I4Z A;  1MDY A;  1NKP B;  1MDY B;  2YPA A;  4H10 A;  2LFH A;  1NLW A;  2YPB A;  3MUJ A;  4ATK A;  4ATH A;  1A0A A;  1UKL C;  4F3L A;  2QL2 A;  1AN4 A;  4AYA A;  1ZZA A;  2MH3 A;  3U5V A;  1R05 A;  5EYO A;  2YPA B;  4H10 B;  1NKP A; 
#chains in the Genus database with same CATH homology
 1NLW B;  2YPB B;  1AM9 A;  1HLO A;  1AN2 A;  4ATI A;  5I50 A;  4F3L B;  2QL2 B;  5I4Z A;  1MDY A;  1NKP B;  1MDY B;  2YPA A;  4H10 A;  2LFH A;  1NLW A;  2YPB A;  3MUJ A;  4ATK A;  4ATH A;  1A0A A;  1UKL C;  4F3L A;  2QL2 A;  1AN4 A;  4AYA A;  2MH3 A;  3U5V A;  1R05 A;  5EYO A;  2YPA B;  4H10 B;  1NKP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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