2M3TA

Solution-state nmr structure of wild-type human gamma(s)-crystallin
Total Genus 21
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
178
structure length
178
Chain Sequence
GSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Preferential and Specific Binding of Human alpha B-Crystallin to a Cataract-Related Variant of gamma S-Crystallin.
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords Beta-crystallin S
total genus 21
structure length 178
sequence length 178
ec nomenclature
pdb deposition date 2013-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00030 Crystall Beta/Gamma crystallin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.20.10 Mainly Beta Sandwich Gamma-B Crystallin; domain 1 Crystallins 2m3tA02
2.60.20.10 Mainly Beta Sandwich Gamma-B Crystallin; domain 1 Crystallins 2m3tA01
1GCSA 4PSPA 1M8UA 3ENTA 1HDFA 3SNYA 1HK0X 1HA4A 2DADA 4FD9A 4GR7A 1AMMA 1AG4A 4JGFA 4NI3A 1PRSA 1ELPA 3QK3A 3SNZA 2B1OA 3SO0A 1ZGTA 2KP5A 2KFBA 2BV2A 2G98A 1H4AX 2K1WA 1PRRA 1I5IA 1ZWMA 1A5DA 1E7NA 4IAUA 1ZIEA 1BD7A 3SO1A 3CW3A 1ZWOA 2K1XA 2M3TA 4GCRA 4W9BA 2V2UA 1NPSA 3ENUA 1DSLA 1YHPA 2JDFA 5HT9A 2BB2A 3LWKA 1GAMA 2A5MA 1A7HA 1BLBA 2JDGA 1A45A 2M3CA 2M3UA 3I9HA 4W9AA 1OKIA 3HZBA 2NBRA 4AKAA 1YTQA 4PSRA 1ZIRA 4EL6A 5HT8A 3HZ2A 1ZIQA 3IAJA
chains in the Genus database with same CATH superfamily
1GCSA 1M8UA 3SNYA 1GH5A 2DADA 4FD9A 4GR7A 4NI3A 1PRSA 2B1OA 2G98A 1H4AX 1ZWMA 2K1XA 4W9BA 2V2UA 1DSLA 1F53A 3LWKA 3SO1A 1A7HA 1BLBA 2M3UA 3UJZA 4PSRA 4EL6A 3HZ2A 4PSPA 1AG4A 1ELPA 3SNZA 1ZGTA 1PRRA 1A5DA 1E7NA 1ZIEA 3CW3A 1ZWOA 1C01A 2JDFA 5HT9A 2A5MA 2M3CA 3I9HA 4W9AA 1OKIA 3HZBA 1ZIRA 1ZIQA 3ENTA 1HK0X 1AMMA 3QK3A 2K1WA 2M3TA 3ENUA 1YHPA 2BB2A 1A45A 2NBRA 4AKAA 1HDFA 1HA4A 4JGFA 3SO0A 2KP5A 2KFBA 2BV2A 1I5IA 4IAUA 1G6EA 1BD7A 4GCRA 1NPSA 1WKTA 1GAMA 2JDGA 1YTQA 5HT8A 1BHUA 3IAJA
chains in the Genus database with same CATH topology
1GCSA 4PSPA 1M8UA 3ENTA 1HDFA 3SNYA 1HK0X 1HA4A 2DADA 4FD9A 4GR7A 1AMMA 1AG4A 4JGFA 4NI3A 1PRSA 1ELPA 3QK3A 3SNZA 2B1OA 3SO0A 1ZGTA 2KP5A 2KFBA 2BV2A 2G98A 1H4AX 2K1WA 1PRRA 1I5IA 1ZWMA 1A5DA 1E7NA 4IAUA 1ZIEA 1BD7A 3SO1A 3CW3A 1ZWOA 2K1XA 2M3TA 4GCRA 4W9BA 2V2UA 1NPSA 3ENUA 1DSLA 1YHPA 2JDFA 5HT9A 2BB2A 3LWKA 1GAMA 2A5MA 1A7HA 1BLBA 2JDGA 1A45A 2M3CA 2M3UA 3I9HA 4W9AA 1OKIA 3HZBA 2NBRA 4AKAA 1YTQA 4PSRA 1ZIRA 4EL6A 5HT8A 3HZ2A 1ZIQA 3IAJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GCS A;  4PSP A;  1M8U A;  3ENT A;  1HDF A;  3SNY A;  1HK0 X;  1HA4 A;  2DAD A;  4FD9 A;  4GR7 A;  1AMM A;  1AG4 A;  4JGF A;  4NI3 A;  1PRS A;  1ELP A;  3QK3 A;  3SNZ A;  2B1O A;  3SO0 A;  1ZGT A;  2KP5 A;  2KFB A;  2BV2 A;  2G98 A;  1H4A X;  2K1W A;  1PRR A;  1I5I A;  1ZWM A;  1A5D A;  1E7N A;  4IAU A;  1ZIE A;  1BD7 A;  3SO1 A;  3CW3 A;  1ZWO A;  2K1X A;  2M3T A;  4GCR A;  4W9B A;  2V2U A;  1NPS A;  3ENU A;  1DSL A;  1YHP A;  2JDF A;  5HT9 A;  2BB2 A;  3LWK A;  1GAM A;  2A5M A;  1A7H A;  1BLB A;  2JDG A;  1A45 A;  2M3C A;  2M3U A;  3I9H A;  4W9A A;  1OKI A;  3HZB A;  2NBR A;  4AKA A;  1YTQ A;  4PSR A;  1ZIR A;  4EL6 A;  5HT8 A;  3HZ2 A;  1ZIQ A;  3IAJ A; 
#chains in the Genus database with same CATH topology
 1GCS A;  1M8U A;  3SNY A;  1GH5 A;  2DAD A;  4FD9 A;  4GR7 A;  4NI3 A;  1PRS A;  2B1O A;  2G98 A;  1H4A X;  1ZWM A;  2K1X A;  4W9B A;  2V2U A;  1DSL A;  1F53 A;  3LWK A;  3SO1 A;  1A7H A;  1BLB A;  2M3U A;  3UJZ A;  4PSR A;  4EL6 A;  3HZ2 A;  4PSP A;  1AG4 A;  1ELP A;  3SNZ A;  1ZGT A;  1PRR A;  1A5D A;  1E7N A;  1ZIE A;  3CW3 A;  1ZWO A;  1C01 A;  2JDF A;  5HT9 A;  2A5M A;  2M3C A;  3I9H A;  4W9A A;  1OKI A;  3HZB A;  1ZIR A;  1ZIQ A;  3ENT A;  1HK0 X;  1AMM A;  3QK3 A;  2K1W A;  2M3T A;  3ENU A;  1YHP A;  2BB2 A;  1A45 A;  2NBR A;  4AKA A;  1HDF A;  1HA4 A;  4JGF A;  3SO0 A;  2KP5 A;  2KFB A;  2BV2 A;  1I5I A;  4IAU A;  1G6E A;  1BD7 A;  4GCR A;  1NPS A;  1WKT A;  1GAM A;  2JDG A;  1YTQ A;  5HT8 A;  1BHU A;  3IAJ A; 
#chains in the Genus database with same CATH homology
 1GCS A;  4PSP A;  1M8U A;  3ENT A;  1HDF A;  3SNY A;  1HK0 X;  1HA4 A;  2DAD A;  4FD9 A;  4GR7 A;  1AMM A;  1AG4 A;  4JGF A;  4NI3 A;  1PRS A;  1ELP A;  3QK3 A;  3SNZ A;  2B1O A;  3SO0 A;  1ZGT A;  2KP5 A;  2KFB A;  2BV2 A;  2G98 A;  1H4A X;  2K1W A;  1PRR A;  1I5I A;  1ZWM A;  1A5D A;  1E7N A;  4IAU A;  1ZIE A;  1BD7 A;  3SO1 A;  3CW3 A;  1ZWO A;  2K1X A;  2M3T A;  4GCR A;  4W9B A;  2V2U A;  1NPS A;  3ENU A;  1DSL A;  1YHP A;  2JDF A;  5HT9 A;  2BB2 A;  3LWK A;  1GAM A;  2A5M A;  1A7H A;  1BLB A;  2JDG A;  1A45 A;  2M3C A;  2M3U A;  3I9H A;  4W9A A;  1OKI A;  3HZB A;  2NBR A;  4AKA A;  1YTQ A;  4PSR A;  1ZIR A;  4EL6 A;  5HT8 A;  3HZ2 A;  1ZIQ A;  3IAJ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...