2M3TA

Solution-state nmr structure of wild-type human gamma(s)-crystallin
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
178
structure length
178
Chain Sequence
GSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Structural protein
source organism Homo sapiens
publication title Preferential and Specific Binding of Human alpha B-Crystallin to a Cataract-Related Variant of gamma S-Crystallin.
pubmed doi rcsb
molecule keywords Beta-crystallin S
total genus 21
structure length 178
sequence length 178
ec nomenclature
pdb deposition date 2013-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00030 Crystall Beta/Gamma crystallin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.20.10 Mainly Beta Sandwich Gamma-B Crystallin; domain 1 Crystallins 2m3tA02
2.60.20.10 Mainly Beta Sandwich Gamma-B Crystallin; domain 1 Crystallins 2m3tA01
2DADA 4GR7A 1DSLA 2G98A 3ENTA 5HT9A 1HDFA 1ZGTA 1AG4A 2A5MA 1ELPA 2K1WA 4PSRA 3I9HA 3QK3A 5HT8A 1HA4A 1H4AX 3HZBA 4EL6A 4W9AA 4W9BA 1AMMA 3SO1A 4IAUA 1HK0X 1OKIA 2V2UA 1ZIEA 2JDFA 3SNZA 2K1XA 2M3CA 4JGFA 3CW3A 1ZWMA 2BB2A 2KFBA 4NI3A 4PSPA 2NBRA 3IAJA 3SNYA 3SO0A 1GCSA 1BLBA 1PRRA 1YHPA 2B1OA 4FD9A 4AKAA 1M8UA 1I5IA 2M3UA 3HZ2A 2KP5A 2JDGA 1ZIRA 3LWKA 1A45A 1YTQA 1ZWOA 1BD7A 3ENUA 4GCRA 2BV2A 1E7NA 1A7HA 1GAMA 1A5DA 1NPSA 1ZIQA 1PRSA 2M3TA
chains in the Genus database with same CATH superfamily
2DADA 1HDFA 1ZGTA 2A5MA 1GH5A 1HA4A 1AMMA 3SO1A 4IAUA 1HK0X 2V2UA 1ZIEA 2JDFA 4NI3A 2NBRA 3SO0A 1PRRA 4AKAA 2KP5A 1BHUA 1ZIRA 3LWKA 4GCRA 2M3TA 1F53A 4GR7A 1ELPA 3QK3A 3HZBA 1G6EA 3UJZA 3CW3A 2BB2A 4PSPA 3IAJA 3SNYA 2B1OA 2JDGA 1A45A 1ZWOA 3ENUA 1E7NA 1A7HA 1NPSA 1A5DA 1DSLA 2G98A 3ENTA 5HT8A 4PSRA 1WKTA 1H4AX 4W9BA 2K1XA 2M3CA 2KFBA 1BLBA 1YHPA 5HT9A 4FD9A 1I5IA 1M8UA 2M3UA 1BD7A 2BV2A 1ZIQA 1C01A 2K1WA 1AG4A 3I9HA 4EL6A 4W9AA 1OKIA 3SNZA 4JGFA 1ZWMA 1GCSA 3HZ2A 1YTQA 1GAMA 1PRSA
chains in the Genus database with same CATH topology
2DADA 4GR7A 1DSLA 2G98A 3ENTA 5HT9A 1HDFA 1ZGTA 1AG4A 2A5MA 1ELPA 2K1WA 4PSRA 3I9HA 3QK3A 5HT8A 1HA4A 1H4AX 3HZBA 4EL6A 4W9AA 4W9BA 1AMMA 3SO1A 4IAUA 1HK0X 1OKIA 2V2UA 1ZIEA 2JDFA 3SNZA 2K1XA 2M3CA 4JGFA 3CW3A 1ZWMA 2BB2A 2KFBA 4NI3A 4PSPA 2NBRA 3IAJA 3SNYA 3SO0A 1GCSA 1BLBA 1PRRA 1YHPA 2B1OA 4FD9A 4AKAA 1M8UA 1I5IA 2M3UA 3HZ2A 2KP5A 2JDGA 1ZIRA 3LWKA 1A45A 1YTQA 1ZWOA 1BD7A 3ENUA 4GCRA 2BV2A 1E7NA 1A7HA 1GAMA 1A5DA 1NPSA 1ZIQA 1PRSA 2M3TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DAD A;  4GR7 A;  1DSL A;  2G98 A;  3ENT A;  5HT9 A;  1HDF A;  1ZGT A;  1AG4 A;  2A5M A;  1ELP A;  2K1W A;  4PSR A;  3I9H A;  3QK3 A;  5HT8 A;  1HA4 A;  1H4A X;  3HZB A;  4EL6 A;  4W9A A;  4W9B A;  1AMM A;  3SO1 A;  4IAU A;  1HK0 X;  1OKI A;  2V2U A;  1ZIE A;  2JDF A;  3SNZ A;  2K1X A;  2M3C A;  4JGF A;  3CW3 A;  1ZWM A;  2BB2 A;  2KFB A;  4NI3 A;  4PSP A;  2NBR A;  3IAJ A;  3SNY A;  3SO0 A;  1GCS A;  1BLB A;  1PRR A;  1YHP A;  2B1O A;  4FD9 A;  4AKA A;  1M8U A;  1I5I A;  2M3U A;  3HZ2 A;  2KP5 A;  2JDG A;  1ZIR A;  3LWK A;  1A45 A;  1YTQ A;  1ZWO A;  1BD7 A;  3ENU A;  4GCR A;  2BV2 A;  1E7N A;  1A7H A;  1GAM A;  1A5D A;  1NPS A;  1ZIQ A;  1PRS A;  2M3T A; 
#chains in the Genus database with same CATH topology
 2DAD A;  1HDF A;  1ZGT A;  2A5M A;  1GH5 A;  1HA4 A;  1AMM A;  3SO1 A;  4IAU A;  1HK0 X;  2V2U A;  1ZIE A;  2JDF A;  4NI3 A;  2NBR A;  3SO0 A;  1PRR A;  4AKA A;  2KP5 A;  1BHU A;  1ZIR A;  3LWK A;  4GCR A;  2M3T A;  1F53 A;  4GR7 A;  1ELP A;  3QK3 A;  3HZB A;  1G6E A;  3UJZ A;  3CW3 A;  2BB2 A;  4PSP A;  3IAJ A;  3SNY A;  2B1O A;  2JDG A;  1A45 A;  1ZWO A;  3ENU A;  1E7N A;  1A7H A;  1NPS A;  1A5D A;  1DSL A;  2G98 A;  3ENT A;  5HT8 A;  4PSR A;  1WKT A;  1H4A X;  4W9B A;  2K1X A;  2M3C A;  2KFB A;  1BLB A;  1YHP A;  5HT9 A;  4FD9 A;  1I5I A;  1M8U A;  2M3U A;  1BD7 A;  2BV2 A;  1ZIQ A;  1C01 A;  2K1W A;  1AG4 A;  3I9H A;  4EL6 A;  4W9A A;  1OKI A;  3SNZ A;  4JGF A;  1ZWM A;  1GCS A;  3HZ2 A;  1YTQ A;  1GAM A;  1PRS A; 
#chains in the Genus database with same CATH homology
 2DAD A;  4GR7 A;  1DSL A;  2G98 A;  3ENT A;  5HT9 A;  1HDF A;  1ZGT A;  1AG4 A;  2A5M A;  1ELP A;  2K1W A;  4PSR A;  3I9H A;  3QK3 A;  5HT8 A;  1HA4 A;  1H4A X;  3HZB A;  4EL6 A;  4W9A A;  4W9B A;  1AMM A;  3SO1 A;  4IAU A;  1HK0 X;  1OKI A;  2V2U A;  1ZIE A;  2JDF A;  3SNZ A;  2K1X A;  2M3C A;  4JGF A;  3CW3 A;  1ZWM A;  2BB2 A;  2KFB A;  4NI3 A;  4PSP A;  2NBR A;  3IAJ A;  3SNY A;  3SO0 A;  1GCS A;  1BLB A;  1PRR A;  1YHP A;  2B1O A;  4FD9 A;  4AKA A;  1M8U A;  1I5I A;  2M3U A;  3HZ2 A;  2KP5 A;  2JDG A;  1ZIR A;  3LWK A;  1A45 A;  1YTQ A;  1ZWO A;  1BD7 A;  3ENU A;  4GCR A;  2BV2 A;  1E7N A;  1A7H A;  1GAM A;  1A5D A;  1NPS A;  1ZIQ A;  1PRS A;  2M3T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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