The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
23
|
sequence length |
70
|
structure length |
70
|
Chain Sequence |
MKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQ
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
The basic helix-loop-helix region of the transcriptional repressor hairy and enhancer of split 1 is preorganized to bind DNA.
pubmed doi rcsb |
| molecule tags |
Dna binding protein
|
| source organism |
Homo sapiens
|
| molecule keywords |
Transcription factor HES-1
|
| total genus |
23
|
| structure length |
70
|
| sequence length |
70
|
| chains with identical sequence |
B
|
| ec nomenclature | |
| pdb deposition date | 2013-11-15 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00010 | HLH | Helix-loop-helix DNA-binding domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Few Secondary Structures | Irregular | MYOD Basic-Helix-Loop-Helix Domain, subunit B | Helix-loop-helix DNA-binding domain |
#chains in the Genus database with same CATH superfamily 2YPA A; 1NLW B; 3MUJ A; 2QL2 B; 4ATK A; 1NKP B; 1NLW A; 4ATI A; 4H10 B; 2QL2 A; 1AM9 A; 1NKP A; 5I4Z A; 2MH3 A; 5EYO A; 1AN2 A; 4AYA A; 4H10 A; 1A0A A; 1MDY B; 1UKL C; 2YPB B; 1MDY A; 3U5V A; 1HLO A; 1AN4 A; 4F3L B; 2YPB A; 2LFH A; 4ATH A; 2YPA B; 1R05 A; 4F3L A; 5I50 A; #chains in the Genus database with same CATH topology 2YPA A; 1NLW B; 3MUJ A; 1ZZA A; 2QL2 B; 4ATK A; 1NKP B; 1NLW A; 4ATI A; 4H10 B; 2QL2 A; 1AM9 A; 1NKP A; 5I4Z A; 2MH3 A; 5EYO A; 1AN2 A; 4AYA A; 4H10 A; 1A0A A; 1MDY B; 1K1F A; 1UKL C; 2YPB B; 1MDY A; 3U5V A; 1HLO A; 1AN4 A; 4F3L B; 2YPB A; 2LFH A; 4ATH A; 2YPA B; 1R05 A; 4F3L A; 5I50 A; #chains in the Genus database with same CATH homology 2YPA A; 1NLW B; 3MUJ A; 2QL2 B; 4ATK A; 1NKP B; 1NLW A; 4ATI A; 4H10 B; 2QL2 A; 1AM9 A; 1NKP A; 5I4Z A; 2MH3 A; 5EYO A; 1AN2 A; 4AYA A; 4H10 A; 1A0A A; 1MDY B; 1UKL C; 2YPB B; 1MDY A; 3U5V A; 1HLO A; 1AN4 A; 4F3L B; 2YPB A; 2LFH A; 4ATH A; 2YPA B; 1R05 A; 4F3L A; 5I50 A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
