2NBRA

The solution structure of human gammac-crystallin
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
173
structure length
173
Chain Sequence
GKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRRGEYPDYQQWMGLSDSIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Nuclear Magnetic Resonance Structure of a Major Lens Protein, Human gamma C-Crystallin: Role of the Dipole Moment in Protein Solubility.
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords Gamma-crystallin C
total genus 38
structure length 173
sequence length 173
ec nomenclature
pdb deposition date 2016-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00030 Crystall Beta/Gamma crystallin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.20.10 Mainly Beta Sandwich Gamma-B Crystallin; domain 1 Crystallins 2nbrA02
2.60.20.10 Mainly Beta Sandwich Gamma-B Crystallin; domain 1 Crystallins 2nbrA01
4EL6A 1ELPA 4FD9A 1A7HA 2JDFA 3SO1A 3SO0A 1ZGTA 2A5MA 1NPSA 3HZ2A 1YTQA 2M3UA 1GCSA 1OKIA 1ZIRA 2BB2A 3SNZA 4PSPA 2DADA 4IAUA 4AKAA 1ZIEA 2KFBA 1ZWMA 2V2UA 4GCRA 4NI3A 3I9HA 2KP5A 1AG4A 3SNYA 2B1OA 4W9AA 5HT8A 1DSLA 1BD7A 1H4AX 3QK3A 1A45A 2K1WA 3ENUA 4PSRA 1ZWOA 1PRSA 2NBRA 1A5DA 1ZIQA 2BV2A 2K1XA 3ENTA 1HK0X 1HDFA 1AMMA 1HA4A 1YHPA 2JDGA 2M3CA 1I5IA 2M3TA 3LWKA 1PRRA 1GAMA 3HZBA 1BLBA 4W9BA 3CW3A 5HT9A 2G98A 3IAJA 4GR7A 1E7NA 4JGFA 1M8UA
chains in the Genus database with same CATH superfamily
4FD9A 1C01A 2DADA 2V2UA 4NI3A 1AG4A 3SNYA 1PRSA 3ENTA 1A5DA 1HK0X 1AMMA 1GAMA 1WKTA 5HT9A 1ELPA 1A7HA 1ZGTA 4AKAA 3I9HA 3UJZA 5HT8A 1GH5A 1A45A 2NBRA 2M3CA 3LWKA 1I5IA 3HZBA 4PSPA 4GR7A 4EL6A 2JDFA 1NPSA 1G6EA 1YTQA 3SNZA 1ZIRA 1BHUA 1DSLA 1H4AX 3ENUA 2K1WA 1ZWOA 1ZIQA 2BV2A 2K1XA 1HDFA 1YHPA 2JDGA 4W9BA 1PRRA 1BLBA 1E7NA 3SO1A 3SO0A 2A5MA 3HZ2A 2M3UA 1GCSA 1OKIA 2BB2A 4IAUA 1ZIEA 2KFBA 1ZWMA 4GCRA 2KP5A 2B1OA 4W9AA 1BD7A 1F53A 4PSRA 3QK3A 1HA4A 2M3TA 3CW3A 2G98A 3IAJA 4JGFA 1M8UA
chains in the Genus database with same CATH topology
4EL6A 1ELPA 4FD9A 1A7HA 2JDFA 3SO1A 3SO0A 1ZGTA 2A5MA 1NPSA 3HZ2A 1YTQA 2M3UA 1GCSA 1OKIA 1ZIRA 2BB2A 3SNZA 4PSPA 2DADA 4IAUA 4AKAA 1ZIEA 2KFBA 1ZWMA 2V2UA 4GCRA 4NI3A 3I9HA 2KP5A 1AG4A 3SNYA 2B1OA 4W9AA 5HT8A 1DSLA 1BD7A 1H4AX 3QK3A 1A45A 2K1WA 3ENUA 4PSRA 1ZWOA 1PRSA 2NBRA 1A5DA 1ZIQA 2BV2A 2K1XA 3ENTA 1HK0X 1HDFA 1AMMA 1HA4A 1YHPA 2JDGA 2M3CA 1I5IA 2M3TA 3LWKA 1PRRA 1GAMA 3HZBA 1BLBA 4W9BA 3CW3A 5HT9A 2G98A 3IAJA 4GR7A 1E7NA 4JGFA 1M8UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EL6 A;  1ELP A;  4FD9 A;  1A7H A;  2JDF A;  3SO1 A;  3SO0 A;  1ZGT A;  2A5M A;  1NPS A;  3HZ2 A;  1YTQ A;  2M3U A;  1GCS A;  1OKI A;  1ZIR A;  2BB2 A;  3SNZ A;  4PSP A;  2DAD A;  4IAU A;  4AKA A;  1ZIE A;  2KFB A;  1ZWM A;  2V2U A;  4GCR A;  4NI3 A;  3I9H A;  2KP5 A;  1AG4 A;  3SNY A;  2B1O A;  4W9A A;  5HT8 A;  1DSL A;  1BD7 A;  1H4A X;  3QK3 A;  1A45 A;  2K1W A;  3ENU A;  4PSR A;  1ZWO A;  1PRS A;  2NBR A;  1A5D A;  1ZIQ A;  2BV2 A;  2K1X A;  3ENT A;  1HK0 X;  1HDF A;  1AMM A;  1HA4 A;  1YHP A;  2JDG A;  2M3C A;  1I5I A;  2M3T A;  3LWK A;  1PRR A;  1GAM A;  3HZB A;  1BLB A;  4W9B A;  3CW3 A;  5HT9 A;  2G98 A;  3IAJ A;  4GR7 A;  1E7N A;  4JGF A;  1M8U A; 
#chains in the Genus database with same CATH topology
 4FD9 A;  1C01 A;  2DAD A;  2V2U A;  4NI3 A;  1AG4 A;  3SNY A;  1PRS A;  3ENT A;  1A5D A;  1HK0 X;  1AMM A;  1GAM A;  1WKT A;  5HT9 A;  1ELP A;  1A7H A;  1ZGT A;  4AKA A;  3I9H A;  3UJZ A;  5HT8 A;  1GH5 A;  1A45 A;  2NBR A;  2M3C A;  3LWK A;  1I5I A;  3HZB A;  4PSP A;  4GR7 A;  4EL6 A;  2JDF A;  1NPS A;  1G6E A;  1YTQ A;  3SNZ A;  1ZIR A;  1BHU A;  1DSL A;  1H4A X;  3ENU A;  2K1W A;  1ZWO A;  1ZIQ A;  2BV2 A;  2K1X A;  1HDF A;  1YHP A;  2JDG A;  4W9B A;  1PRR A;  1BLB A;  1E7N A;  3SO1 A;  3SO0 A;  2A5M A;  3HZ2 A;  2M3U A;  1GCS A;  1OKI A;  2BB2 A;  4IAU A;  1ZIE A;  2KFB A;  1ZWM A;  4GCR A;  2KP5 A;  2B1O A;  4W9A A;  1BD7 A;  1F53 A;  4PSR A;  3QK3 A;  1HA4 A;  2M3T A;  3CW3 A;  2G98 A;  3IAJ A;  4JGF A;  1M8U A; 
#chains in the Genus database with same CATH homology
 4EL6 A;  1ELP A;  4FD9 A;  1A7H A;  2JDF A;  3SO1 A;  3SO0 A;  1ZGT A;  2A5M A;  1NPS A;  3HZ2 A;  1YTQ A;  2M3U A;  1GCS A;  1OKI A;  1ZIR A;  2BB2 A;  3SNZ A;  4PSP A;  2DAD A;  4IAU A;  4AKA A;  1ZIE A;  2KFB A;  1ZWM A;  2V2U A;  4GCR A;  4NI3 A;  3I9H A;  2KP5 A;  1AG4 A;  3SNY A;  2B1O A;  4W9A A;  5HT8 A;  1DSL A;  1BD7 A;  1H4A X;  3QK3 A;  1A45 A;  2K1W A;  3ENU A;  4PSR A;  1ZWO A;  1PRS A;  2NBR A;  1A5D A;  1ZIQ A;  2BV2 A;  2K1X A;  3ENT A;  1HK0 X;  1HDF A;  1AMM A;  1HA4 A;  1YHP A;  2JDG A;  2M3C A;  1I5I A;  2M3T A;  3LWK A;  1PRR A;  1GAM A;  3HZB A;  1BLB A;  4W9B A;  3CW3 A;  5HT9 A;  2G98 A;  3IAJ A;  4GR7 A;  1E7N A;  4JGF A;  1M8U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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