2PFRA

Human n-acetyltransferase 2
Total Genus 90

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
290
structure length
290
Chain Sequence
SDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMELGLEAIFDHIVRRNRGGWCLQVNQLLYWALTTIGFQTTMLGGYFYIPPVNKYSTGMVHLLLQVTIDGRNYIVDAGSGSSSQMWQPLELISGKDQPQVPCIFCLTEERGIWYLDQIRREQYITNKEFLNSHLLPKKKHQKIYLFTLEPRTIEDFESMNTYLQTSPTSSFITTSFCSLQTPEGVYCLVGFILTYRKFNYKDNTDLVEFKTLTEEEVEEVLKNIFKISLGRNLVPKPGDGSLTI

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
AH1 (2-10)AH2 (21-33)AH3 (52-61)EMPTYO1 (13-15)TIV3 (131-134)AH4 (68-82)S12 (222-227)S1 (37-38)3H1 (40-43)3H5 (216-218)O2 (104-106)3H2 (96-98)S2 (85-95)S3 (100-101)S4 (107-114)TIV2 (122-125)O3 (136-138)S5 (117-121)S11 (186-197)TII'1 (126-129)TVIII2 (286-289)S9 (158-164)TI1 (127-130)S6 (135-136)TII1 (138-141)S7 (141-145)TI2 (145-148)S8 (148-155)TIV4 (154-157)TVIII1 (184-187)S10 (167-170)S14 (238-247)TI4 (178-181)3H4 (199-202)TI6 (227-230)S13 (230-235)S15 (250-257)TIV7 (247-250)TIV8 (284-287)3H3 (173-175)TI3 (175-178)AH5 (203-210)TI5 (212-215)TIV5 (234-237)AH6 (260-271)Updating...
connected with : NaN
publication title The Crystal Structure of Human N-acetyltransferase 2 in complex with CoA
rcsb
molecule keywords Arylamine N-acetyltransferase 2
molecule tags Transferase
source organism Homo sapiens
total genus 90
structure length 290
sequence length 290
chains with identical sequence B
ec nomenclature ec 2.3.1.5: Arylamine N-acetyltransferase.
pdb deposition date 2007-04-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00797 Acetyltransf_2 N-acetyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2140.20 Alpha Beta 2-Layer Sandwich Arylamine N-acetyltransferase fold Arylamine N-acetyltransferase fold 2pfrA00
4DMOA 3LNBA 2IJAA 2PQTA 2PFRA
chains in the Genus database with same CATH superfamily
3LNBA 2BSZA 1W5RA 3D9WA 2VFCA 4GUZA 2VFBA 2IJAA 4BGFA 4B55A 1W6FA 4DMOA 3LTWA 1GX3A 4C5PA 4NV8A 1W4TA 2PQTA 4NV7A 2PFRA
chains in the Genus database with same CATH topology
4DMOA 3LNBA 2IJAA 2PQTA 2PFRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DMO A;  3LNB A;  2IJA A;  2PQT A;  2PFR A; 
#chains in the Genus database with same CATH topology
 3LNB A;  2BSZ A;  1W5R A;  3D9W A;  2VFC A;  4GUZ A;  2VFB A;  2IJA A;  4BGF A;  4B55 A;  1W6F A;  4DMO A;  3LTW A;  1GX3 A;  4C5P A;  4NV8 A;  1W4T A;  2PQT A;  4NV7 A;  2PFR A; 
#chains in the Genus database with same CATH homology
 4DMO A;  3LNB A;  2IJA A;  2PQT A;  2PFR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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