2PQT | Genus

Total Genus 93

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	93
sequence length	295
structure length	294
Chain Sequence	GSGSGSDIEAYFERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVRRNRGGWLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIVDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLLEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTHRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVPKHGDRFFTI

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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Time for openFile(/file/5cfd72c3989982d829558e1d/pdb.gz): 1054 ms

reading 294 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

294 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 25 ms

Adding embedded #jmolscript: select ({0:293});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Structural Basis of Substrate-binding Specificity of Human Arylamine N-Acetyltransferases. pubmed doi rcsb
molecule keywords	Arylamine N-acetyltransferase 1
molecule tags	Transferase
source organism	Homo sapiens
total genus	93
structure length	294
sequence length	295
ec nomenclature	ec 2.3.1.5: Arylamine N-acetyltransferase.
pdb deposition date	2007-05-02

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00797	Acetyltransf_2	N-acetyltransferase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.2140.20	Alpha Beta	2-Layer Sandwich	Arylamine N-acetyltransferase fold	Arylamine N-acetyltransferase fold	2pqtA00

2PFRA 4DMOA 2IJAA 3LNBA 2PQTA
chains in the Genus database with same CATH superfamily

1W6FA 2PQTA 4NV7A 3D9WA 2BSZA 2VFCA 3LTWA 2VFBA 1GX3A 4BGFA 1W4TA 2IJAA 3LNBA 4B55A 4NV8A 4C5PA 2PFRA 4GUZA 4DMOA 1W5RA
chains in the Genus database with same CATH topology

2PFRA 4DMOA 2IJAA 3LNBA 2PQTA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2PFR A;  4DMO A;  2IJA A;  3LNB A;  2PQT A; 
#chains in the Genus database with same CATH topology
 1W6F A;  2PQT A;  4NV7 A;  3D9W A;  2BSZ A;  2VFC A;  3LTW A;  2VFB A;  1GX3 A;  4BGF A;  1W4T A;  2IJA A;  3LNB A;  4B55 A;  4NV8 A;  4C5P A;  2PFR A;  4GUZ A;  4DMO A;  1W5R A; 
#chains in the Genus database with same CATH homology
 2PFR A;  4DMO A;  2IJA A;  3LNB A;  2PQT A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2PQTA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations