2QL2A

Crystal structure of the basic-helix-loop-helix domains of the heterodimer e47/neurod1 bound to dna
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
59
structure length
56
Chain Sequence
RRMANNARERVRVRDINEAFRELGRMCQLHLKAQTKLLILQQAVQVILGLEQQVRE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Mus musculus
molecule keywords Transcription factor E2-alpha
total genus 25
structure length 56
sequence length 59
chains with identical sequence C
ec nomenclature
pdb deposition date 2007-07-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 2ql2A00
1NLWA 3U5VA 2YPAB 1AN2A 2YPAA 4ATHA 4F3LB 4F3LA 4AYAA 2LFHA 1AM9A 5I50A 1UKLC 1MDYB 1MDYA 5EYOA 1R05A 1HLOA 5I4ZA 2MH3A 2YPBB 4ATIA 2YPBA 1A0AA 4ATKA 2QL2B 3MUJA 1AN4A 4H10B 4H10A 2QL2A 1NKPB 1NKPA 1NLWB
chains in the Genus database with same CATH superfamily
1NLWA 3U5VA 1ZZAA 2YPAB 1AN2A 2YPAA 4ATHA 4F3LB 4F3LA 4AYAA 2LFHA 1AM9A 1K1FA 5I50A 1UKLC 1MDYB 1MDYA 5EYOA 1R05A 1HLOA 5I4ZA 2MH3A 2YPBB 4ATIA 2YPBA 1A0AA 4ATKA 2QL2B 3MUJA 1AN4A 4H10B 4H10A 2QL2A 1NKPB 1NKPA 1NLWB
chains in the Genus database with same CATH topology
1NLWA 3U5VA 2YPAB 1AN2A 2YPAA 4ATHA 4F3LB 4F3LA 4AYAA 2LFHA 1AM9A 5I50A 1UKLC 1MDYB 1MDYA 5EYOA 1R05A 1HLOA 5I4ZA 2MH3A 2YPBB 4ATIA 2YPBA 1A0AA 4ATKA 2QL2B 3MUJA 1AN4A 4H10B 4H10A 2QL2A 1NKPB 1NKPA 1NLWB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NLW A;  3U5V A;  2YPA B;  1AN2 A;  2YPA A;  4ATH A;  4F3L B;  4F3L A;  4AYA A;  2LFH A;  1AM9 A;  5I50 A;  1UKL C;  1MDY B;  1MDY A;  5EYO A;  1R05 A;  1HLO A;  5I4Z A;  2MH3 A;  2YPB B;  4ATI A;  2YPB A;  1A0A A;  4ATK A;  2QL2 B;  3MUJ A;  1AN4 A;  4H10 B;  4H10 A;  2QL2 A;  1NKP B;  1NKP A;  1NLW B; 
#chains in the Genus database with same CATH topology
 1NLW A;  3U5V A;  1ZZA A;  2YPA B;  1AN2 A;  2YPA A;  4ATH A;  4F3L B;  4F3L A;  4AYA A;  2LFH A;  1AM9 A;  1K1F A;  5I50 A;  1UKL C;  1MDY B;  1MDY A;  5EYO A;  1R05 A;  1HLO A;  5I4Z A;  2MH3 A;  2YPB B;  4ATI A;  2YPB A;  1A0A A;  4ATK A;  2QL2 B;  3MUJ A;  1AN4 A;  4H10 B;  4H10 A;  2QL2 A;  1NKP B;  1NKP A;  1NLW B; 
#chains in the Genus database with same CATH homology
 1NLW A;  3U5V A;  2YPA B;  1AN2 A;  2YPA A;  4ATH A;  4F3L B;  4F3L A;  4AYA A;  2LFH A;  1AM9 A;  5I50 A;  1UKL C;  1MDY B;  1MDY A;  5EYO A;  1R05 A;  1HLO A;  5I4Z A;  2MH3 A;  2YPB B;  4ATI A;  2YPB A;  1A0A A;  4ATK A;  2QL2 B;  3MUJ A;  1AN4 A;  4H10 B;  4H10 A;  2QL2 A;  1NKP B;  1NKP A;  1NLW B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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