2YPAA

Structure of the scl:e47:lmo2:ldb1 complex bound to dna
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
67
structure length
67
Chain Sequence
PHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
source organism Homo sapiens
publication title Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
pubmed doi rcsb
molecule keywords T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1
total genus 23
structure length 67
sequence length 67
ec nomenclature
pdb deposition date 2012-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 2ypaA00
4AYAA 4F3LA 3U5VA 1AN4A 1NLWA 2YPAA 3MUJA 4H10A 1AN2A 1MDYA 5I50A 4F3LB 2QL2A 1NLWB 5EYOA 2YPAB 5I4ZA 2MH3A 1HLOA 4H10B 1NKPA 2YPBA 1UKLC 1AM9A 1MDYB 2LFHA 1R05A 4ATKA 2QL2B 4ATIA 1A0AA 4ATHA 2YPBB 1NKPB
chains in the Genus database with same CATH superfamily
1ZZAA 4AYAA 4F3LA 3U5VA 1AN4A 1NLWA 2YPAA 1K1FA 3MUJA 4H10A 1AN2A 1MDYA 5I50A 4F3LB 2QL2A 1NLWB 5EYOA 2YPAB 5I4ZA 2MH3A 1HLOA 4H10B 1NKPA 2YPBA 1UKLC 1AM9A 1MDYB 2LFHA 1R05A 4ATKA 2QL2B 4ATIA 1A0AA 4ATHA 2YPBB 1NKPB
chains in the Genus database with same CATH topology
4AYAA 4F3LA 3U5VA 1AN4A 1NLWA 2YPAA 3MUJA 4H10A 1AN2A 1MDYA 5I50A 4F3LB 2QL2A 1NLWB 5EYOA 2YPAB 5I4ZA 2MH3A 1HLOA 4H10B 1NKPA 2YPBA 1UKLC 1AM9A 1MDYB 2LFHA 1R05A 4ATKA 2QL2B 4ATIA 1A0AA 4ATHA 2YPBB 1NKPB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AYA A;  4F3L A;  3U5V A;  1AN4 A;  1NLW A;  2YPA A;  3MUJ A;  4H10 A;  1AN2 A;  1MDY A;  5I50 A;  4F3L B;  2QL2 A;  1NLW B;  5EYO A;  2YPA B;  5I4Z A;  2MH3 A;  1HLO A;  4H10 B;  1NKP A;  2YPB A;  1UKL C;  1AM9 A;  1MDY B;  2LFH A;  1R05 A;  4ATK A;  2QL2 B;  4ATI A;  1A0A A;  4ATH A;  2YPB B;  1NKP B; 
#chains in the Genus database with same CATH topology
 1ZZA A;  4AYA A;  4F3L A;  3U5V A;  1AN4 A;  1NLW A;  2YPA A;  1K1F A;  3MUJ A;  4H10 A;  1AN2 A;  1MDY A;  5I50 A;  4F3L B;  2QL2 A;  1NLW B;  5EYO A;  2YPA B;  5I4Z A;  2MH3 A;  1HLO A;  4H10 B;  1NKP A;  2YPB A;  1UKL C;  1AM9 A;  1MDY B;  2LFH A;  1R05 A;  4ATK A;  2QL2 B;  4ATI A;  1A0A A;  4ATH A;  2YPB B;  1NKP B; 
#chains in the Genus database with same CATH homology
 4AYA A;  4F3L A;  3U5V A;  1AN4 A;  1NLW A;  2YPA A;  3MUJ A;  4H10 A;  1AN2 A;  1MDY A;  5I50 A;  4F3L B;  2QL2 A;  1NLW B;  5EYO A;  2YPA B;  5I4Z A;  2MH3 A;  1HLO A;  4H10 B;  1NKP A;  2YPB A;  1UKL C;  1AM9 A;  1MDY B;  2LFH A;  1R05 A;  4ATK A;  2QL2 B;  4ATI A;  1A0A A;  4ATH A;  2YPB B;  1NKP B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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