2QKHA

Crystal structure of the extracellular domain of human gip receptor in complex with the hormone gip
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
94
structure length
94
Chain Sequence
GQTAGELYQRWERYRRECQETLAAAEPPSGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCENPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor
pubmed doi rcsb
molecule tags Signaling protein/hormone
source organism Homo sapiens
molecule keywords Glucose-dependent insulinotropic polypeptide
total genus 26
structure length 94
sequence length 94
ec nomenclature
pdb deposition date 2007-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02793 HRM Hormone receptor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.1240.10 Few Secondary Structures Irregular Hormone receptor fold GPCR, family 2, extracellular hormone receptor domain 2qkhA00
2QKHA 5II0A 3N7PA 3L2JA 3N7SA 4ZGMA 3C59A 1U34A 3AQFB 2L27A 2XDGA 4DLOA 2JNDA 2JNCA 4DLQA 3C5TA 3EHTA 4ERSA 3C4MA 3EHSA 3H3GA 3N7RA 3IOLA 3EHUA 4LF3C 4HJ0A 2JODA
chains in the Genus database with same CATH superfamily
2QKHA 5II0A 3N7PA 3L2JA 3N7SA 4ZGMA 3C59A 1U34A 3AQFB 2L27A 2XDGA 4DLOA 2JNDA 2JNCA 4DLQA 3C5TA 3EHTA 4ERSA 3C4MA 3EHSA 3H3GA 3N7RA 3IOLA 3EHUA 4LF3C 4HJ0A 2JODA
chains in the Genus database with same CATH topology
2QKHA 5II0A 3N7PA 3L2JA 3N7SA 4ZGMA 3C59A 1U34A 3AQFB 2L27A 2XDGA 4DLOA 2JNDA 2JNCA 4DLQA 3C5TA 3EHTA 4ERSA 3C4MA 3EHSA 3H3GA 3N7RA 3IOLA 3EHUA 4LF3C 4HJ0A 2JODA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QKH A;  5II0 A;  3N7P A;  3L2J A;  3N7S A;  4ZGM A;  3C59 A;  1U34 A;  3AQF B;  2L27 A;  2XDG A;  4DLO A;  2JND A;  2JNC A;  4DLQ A;  3C5T A;  3EHT A;  4ERS A;  3C4M A;  3EHS A;  3H3G A;  3N7R A;  3IOL A;  3EHU A;  4LF3 C;  4HJ0 A;  2JOD A; 
#chains in the Genus database with same CATH topology
 2QKH A;  5II0 A;  3N7P A;  3L2J A;  3N7S A;  4ZGM A;  3C59 A;  1U34 A;  3AQF B;  2L27 A;  2XDG A;  4DLO A;  2JND A;  2JNC A;  4DLQ A;  3C5T A;  3EHT A;  4ERS A;  3C4M A;  3EHS A;  3H3G A;  3N7R A;  3IOL A;  3EHU A;  4LF3 C;  4HJ0 A;  2JOD A; 
#chains in the Genus database with same CATH homology
 2QKH A;  5II0 A;  3N7P A;  3L2J A;  3N7S A;  4ZGM A;  3C59 A;  1U34 A;  3AQF B;  2L27 A;  2XDG A;  4DLO A;  2JND A;  2JNC A;  4DLQ A;  3C5T A;  3EHT A;  4ERS A;  3C4M A;  3EHS A;  3H3G A;  3N7R A;  3IOL A;  3EHU A;  4LF3 C;  4HJ0 A;  2JOD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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