2QL2 | Genus

Total Genus 23

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	23
sequence length	59
structure length	59
Chain Sequence	SRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRS

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 59 atoms

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59 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Transcription/dna
source organism	Mus musculus
publication title	Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition. pubmed doi rcsb
molecule keywords	Transcription factor E2-alpha
total genus	23
structure length	59
sequence length	59
chains with identical sequence	D
ec nomenclature
pdb deposition date	2007-07-12

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
B	PF00010	HLH	Helix-loop-helix DNA-binding domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
4.10.280.10	Few Secondary Structures	Irregular	MYOD Basic-Helix-Loop-Helix Domain, subunit B	Helix-loop-helix DNA-binding domain	2ql2B00

5EYOA 1MDYA 2QL2A 4ATKA 1NLWA 1MDYB 2QL2B 1NLWB 5I50A 3MUJA 2LFHA 4ATIA 1AN4A 1NKPB 1HLOA 2MH3A 1R05A 1UKLC 2YPAA 4H10A 2YPAB 4H10B 1A0AA 1AM9A 1AN2A 2YPBB 4ATHA 2YPBA 4F3LB 4F3LA 5I4ZA 4AYAA 3U5VA 1NKPA
chains in the Genus database with same CATH superfamily

1K1FA 5EYOA 1ZZAA 1MDYA 2QL2A 4ATKA 1NLWA 1MDYB 2QL2B 1NLWB 5I50A 3MUJA 2LFHA 4ATIA 1AN4A 1NKPB 1HLOA 2MH3A 1R05A 1UKLC 2YPAA 4H10A 2YPAB 4H10B 1A0AA 1AM9A 1AN2A 2YPBB 4ATHA 2YPBA 4F3LB 4F3LA 5I4ZA 4AYAA 3U5VA 1NKPA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 5EYO A;  1MDY A;  2QL2 A;  4ATK A;  1NLW A;  1MDY B;  2QL2 B;  1NLW B;  5I50 A;  3MUJ A;  2LFH A;  4ATI A;  1AN4 A;  1NKP B;  1HLO A;  2MH3 A;  1R05 A;  1UKL C;  2YPA A;  4H10 A;  2YPA B;  4H10 B;  1A0A A;  1AM9 A;  1AN2 A;  2YPB B;  4ATH A;  2YPB A;  4F3L B;  4F3L A;  5I4Z A;  4AYA A;  3U5V A;  1NKP A; 
#chains in the Genus database with same CATH topology
 1K1F A;  5EYO A;  1ZZA A;  1MDY A;  2QL2 A;  4ATK A;  1NLW A;  1MDY B;  2QL2 B;  1NLW B;  5I50 A;  3MUJ A;  2LFH A;  4ATI A;  1AN4 A;  1NKP B;  1HLO A;  2MH3 A;  1R05 A;  1UKL C;  2YPA A;  4H10 A;  2YPA B;  4H10 B;  1A0A A;  1AM9 A;  1AN2 A;  2YPB B;  4ATH A;  2YPB A;  4F3L B;  4F3L A;  5I4Z A;  4AYA A;  3U5V A;  1NKP A; 
#chains in the Genus database with same CATH homology
 5EYO A;  1MDY A;  2QL2 A;  4ATK A;  1NLW A;  1MDY B;  2QL2 B;  1NLW B;  5I50 A;  3MUJ A;  2LFH A;  4ATI A;  1AN4 A;  1NKP B;  1HLO A;  2MH3 A;  1R05 A;  1UKL C;  2YPA A;  4H10 A;  2YPA B;  4H10 B;  1A0A A;  1AM9 A;  1AN2 A;  2YPB B;  4ATH A;  2YPB A;  4F3L B;  4F3L A;  5I4Z A;  4AYA A;  3U5V A;  1NKP A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2QL2B

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations