2QL2B

Crystal structure of the basic-helix-loop-helix domains of the heterodimer e47/neurod1 bound to dna
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
59
structure length
59
Chain Sequence
SRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition.
pubmed doi rcsb
molecule keywords Transcription factor E2-alpha
molecule tags Transcription/dna
source organism Mus musculus
total genus 23
structure length 59
sequence length 59
chains with identical sequence D
ec nomenclature
pdb deposition date 2007-07-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 2ql2B00
3U5VA 4H10B 1MDYA 5I50A 2YPBB 2QL2B 4H10A 2YPBA 1NKPB 4ATKA 4ATIA 1AM9A 1R05A 2QL2A 2LFHA 4AYAA 1NKPA 2MH3A 1HLOA 2YPAB 1A0AA 4ATHA 5I4ZA 4F3LB 1UKLC 1NLWB 5EYOA 4F3LA 2YPAA 1AN4A 1NLWA 1MDYB 1AN2A 3MUJA
chains in the Genus database with same CATH superfamily
3U5VA 1ZZAA 4H10B 1MDYA 5I50A 2YPBB 2QL2B 4H10A 2YPBA 1NKPB 4ATKA 4ATIA 1AM9A 1R05A 2QL2A 2LFHA 4AYAA 1NKPA 2MH3A 1HLOA 2YPAB 1A0AA 4ATHA 5I4ZA 4F3LB 1UKLC 1NLWB 5EYOA 4F3LA 2YPAA 1AN4A 1NLWA 1MDYB 1K1FA 1AN2A 3MUJA
chains in the Genus database with same CATH topology
3U5VA 4H10B 1MDYA 5I50A 2YPBB 2QL2B 4H10A 2YPBA 1NKPB 4ATKA 4ATIA 1AM9A 1R05A 2QL2A 2LFHA 4AYAA 1NKPA 2MH3A 1HLOA 2YPAB 1A0AA 4ATHA 5I4ZA 4F3LB 1UKLC 1NLWB 5EYOA 4F3LA 2YPAA 1AN4A 1NLWA 1MDYB 1AN2A 3MUJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3U5V A;  4H10 B;  1MDY A;  5I50 A;  2YPB B;  2QL2 B;  4H10 A;  2YPB A;  1NKP B;  4ATK A;  4ATI A;  1AM9 A;  1R05 A;  2QL2 A;  2LFH A;  4AYA A;  1NKP A;  2MH3 A;  1HLO A;  2YPA B;  1A0A A;  4ATH A;  5I4Z A;  4F3L B;  1UKL C;  1NLW B;  5EYO A;  4F3L A;  2YPA A;  1AN4 A;  1NLW A;  1MDY B;  1AN2 A;  3MUJ A; 
#chains in the Genus database with same CATH topology
 3U5V A;  1ZZA A;  4H10 B;  1MDY A;  5I50 A;  2YPB B;  2QL2 B;  4H10 A;  2YPB A;  1NKP B;  4ATK A;  4ATI A;  1AM9 A;  1R05 A;  2QL2 A;  2LFH A;  4AYA A;  1NKP A;  2MH3 A;  1HLO A;  2YPA B;  1A0A A;  4ATH A;  5I4Z A;  4F3L B;  1UKL C;  1NLW B;  5EYO A;  4F3L A;  2YPA A;  1AN4 A;  1NLW A;  1MDY B;  1K1F A;  1AN2 A;  3MUJ A; 
#chains in the Genus database with same CATH homology
 3U5V A;  4H10 B;  1MDY A;  5I50 A;  2YPB B;  2QL2 B;  4H10 A;  2YPB A;  1NKP B;  4ATK A;  4ATI A;  1AM9 A;  1R05 A;  2QL2 A;  2LFH A;  4AYA A;  1NKP A;  2MH3 A;  1HLO A;  2YPA B;  1A0A A;  4ATH A;  5I4Z A;  4F3L B;  1UKL C;  1NLW B;  5EYO A;  4F3L A;  2YPA A;  1AN4 A;  1NLW A;  1MDY B;  1AN2 A;  3MUJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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