2YPBB

Structure of the scl:e47 complex bound to dna
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
74
structure length
74
Chain Sequence
SLEEKDLRDRERRMANNARERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLILQQAVQVILGLEQQVRERNLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1
total genus 28
structure length 74
sequence length 74
ec nomenclature
pdb deposition date 2012-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 2ypbB00
1R05A 1AM9A 4ATKA 2QL2A 1NKPA 1NLWA 2QL2B 5I50A 1NLWB 1NKPB 1AN2A 4AYAA 1UKLC 1AN4A 2YPBA 2YPBB 5EYOA 2YPAA 4H10A 2MH3A 2LFHA 2YPAB 4H10B 4F3LA 4ATIA 4F3LB 5I4ZA 1A0AA 1MDYA 1MDYB 3MUJA 4ATHA 1HLOA 3U5VA
chains in the Genus database with same CATH superfamily
1R05A 1AM9A 4ATKA 2QL2A 1NKPA 1NLWA 2QL2B 5I50A 1NLWB 1NKPB 1AN2A 4AYAA 1UKLC 1AN4A 2YPBA 2YPBB 5EYOA 1K1FA 2YPAA 2MH3A 4H10A 2LFHA 2YPAB 4H10B 1ZZAA 4F3LA 4ATIA 4F3LB 5I4ZA 1A0AA 1MDYA 1MDYB 3MUJA 4ATHA 1HLOA 3U5VA
chains in the Genus database with same CATH topology
1R05A 1AM9A 4ATKA 2QL2A 1NKPA 1NLWA 2QL2B 5I50A 1NLWB 1NKPB 1AN2A 4AYAA 1UKLC 1AN4A 2YPBA 2YPBB 5EYOA 2YPAA 4H10A 2MH3A 2LFHA 2YPAB 4H10B 4F3LA 4ATIA 4F3LB 5I4ZA 1A0AA 1MDYA 1MDYB 3MUJA 4ATHA 1HLOA 3U5VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R05 A;  1AM9 A;  4ATK A;  2QL2 A;  1NKP A;  1NLW A;  2QL2 B;  5I50 A;  1NLW B;  1NKP B;  1AN2 A;  4AYA A;  1UKL C;  1AN4 A;  2YPB A;  2YPB B;  5EYO A;  2YPA A;  4H10 A;  2MH3 A;  2LFH A;  2YPA B;  4H10 B;  4F3L A;  4ATI A;  4F3L B;  5I4Z A;  1A0A A;  1MDY A;  1MDY B;  3MUJ A;  4ATH A;  1HLO A;  3U5V A; 
#chains in the Genus database with same CATH topology
 1R05 A;  1AM9 A;  4ATK A;  2QL2 A;  1NKP A;  1NLW A;  2QL2 B;  5I50 A;  1NLW B;  1NKP B;  1AN2 A;  4AYA A;  1UKL C;  1AN4 A;  2YPB A;  2YPB B;  5EYO A;  1K1F A;  2YPA A;  2MH3 A;  4H10 A;  2LFH A;  2YPA B;  4H10 B;  1ZZA A;  4F3L A;  4ATI A;  4F3L B;  5I4Z A;  1A0A A;  1MDY A;  1MDY B;  3MUJ A;  4ATH A;  1HLO A;  3U5V A; 
#chains in the Genus database with same CATH homology
 1R05 A;  1AM9 A;  4ATK A;  2QL2 A;  1NKP A;  1NLW A;  2QL2 B;  5I50 A;  1NLW B;  1NKP B;  1AN2 A;  4AYA A;  1UKL C;  1AN4 A;  2YPB A;  2YPB B;  5EYO A;  2YPA A;  4H10 A;  2MH3 A;  2LFH A;  2YPA B;  4H10 B;  4F3L A;  4ATI A;  4F3L B;  5I4Z A;  1A0A A;  1MDY A;  1MDY B;  3MUJ A;  4ATH A;  1HLO A;  3U5V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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