3GFDA

Crystal structure of mus musculus iodotyrosine deiodinase (iyd) bound to fmn and mono-iodotyrosine (mit)
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
222
structure length
220
Chain Sequence
SVEHIPFSHTRYPEQEMRMRSQEFYELLNKRRSVRFISSEHVPMEVIENVIKAAGTAPSGAHTEPWTFVVVKDPDMKHKIREIIEEEEEINYMKRMGKRWVTDLKKLRTNWIKEYLDTAPVLILIFKQVHGFNGKKKVHYYNEISVSIACGLLLAALQNAGLVTVTTTPLNCGPRLRVLLGRPSHEKLLVLLPVGYPSRDATVPDLKRKALDQIMVTVHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Mus musculus
molecule keywords Iodotyrosine dehalogenase 1
total genus 60
structure length 220
sequence length 222
chains with identical sequence B
ec nomenclature ec 1.21.1.1: Iodotyrosine deiodinase.
pdb deposition date 2009-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00881 Nitroreductase Nitroreductase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.109.10 Alpha Beta 3-Layer(aba) Sandwich NADH Oxidase NADH Oxidase 3gfdA01
5J6CA 1VFRA 1YLRA 1IDTA 3GB5A 4TTCA 1ICVA 3EO8A 3BEMA 3E39A 2WZVA 2FREA 3X22A 4QLYA 1DS7A 4XOMA 4DN2A 4EO3A 3E10A 3GE5A 3TO0A 2I7HA 3H4OA 3PXVA 1OOQA 2WQFA 3GE6A 1ICUA 1NECA 3GFDA 5KO7A 4BN7A 4BN8A 4XOQA 1KQBA 1OO5A 1VKWA 3TNZA 4URPA 1V5YA 1F5VA 3BM1A 1KQCA 3GAGA 1ZCHA 1OO6A 2B67A 4BN9A 2BKJA 3QDLA 3M5KA 1YWQA 2ISJA 2ISKA 3EK3A 3EO7A 5KO8A 3N2SA 4BNBA 2YMVA 3EOFA 5HEIA 3X21A 1ICRA 1YLUA 1V5ZA 3GBHA 2WZWA 2ISLA 3HOIA 3GFAA 4G8SA 1NOXA 2R01A 3GH8A 3KOQA 3HJ9A 3G14A 2H0UA 5HDJA 4BN6A 3K6HA 3HZNA 1YKIA 4TTBA 3KWKA 5KRDA 2HAYA 3GR3A 1BKJA 4QLXA 2IFAA 1OONA 3BM2A 4XOOA 1KQDA 3OF4A
chains in the Genus database with same CATH superfamily
5J6CA 1VFRA 1YLRA 1IDTA 3GB5A 4TTCA 1ICVA 3EO8A 3BEMA 3E39A 2WZVA 2FREA 3X22A 4QLYA 1DS7A 4XOMA 4DN2A 4EO3A 3E10A 3GE5A 3TO0A 2I7HA 3H4OA 3PXVA 1OOQA 2WQFA 3GE6A 1ICUA 1NECA 3GFDA 5KO7A 4BN7A 4BN8A 1J6RA 4XOQA 1KQBA 1OO5A 1VKWA 3TNZA 1V5YA 4URPA 1F5VA 3BM1A 1KQCA 3GAGA 1ZCHA 1OO6A 2B67A 4BN9A 2BKJA 3QDLA 3M5KA 1YWQA 2ISJA 2ISKA 3EK3A 3EO7A 5KO8A 3N2SA 4BNBA 2YMVA 3EOFA 5HEIA 3X21A 1ICRA 1YLUA 1V5ZA 3GBHA 2WZWA 2ISLA 3HOIA 3GFAA 4G8SA 1NOXA 2R01A 3GH8A 3KOQA 3HJ9A 3G14A 2H0UA 5HDJA 4BN6A 3K6HA 3HZNA 1YKIA 4TTBA 3KWKA 5KRDA 2HAYA 3GR3A 1BKJA 4QLXA 2IFAA 1OONA 3BM2A 4XOOA 1KQDA 3OF4A
chains in the Genus database with same CATH topology
5J6CA 1VFRA 1YLRA 1IDTA 3GB5A 4TTCA 1ICVA 3EO8A 3BEMA 3E39A 2WZVA 2FREA 3X22A 4QLYA 1DS7A 4XOMA 4DN2A 4EO3A 3E10A 3GE5A 3TO0A 2I7HA 3H4OA 3PXVA 1OOQA 2WQFA 3GE6A 1ICUA 1NECA 3GFDA 5KO7A 4BN7A 4BN8A 1J6RA 4XOQA 1KQBA 1OO5A 1VKWA 3TNZA 1V5YA 4URPA 1F5VA 3BM1A 1KQCA 3GAGA 1ZCHA 1OO6A 2B67A 4BN9A 2BKJA 3QDLA 3M5KA 1YWQA 2ISJA 2ISKA 3EK3A 3EO7A 5KO8A 3N2SA 4BNBA 2YMVA 3EOFA 5HEIA 3X21A 1ICRA 1YLUA 1V5ZA 3GBHA 2WZWA 2ISLA 3HOIA 3GFAA 4G8SA 1NOXA 2R01A 3GH8A 3KOQA 3HJ9A 3G14A 2H0UA 5HDJA 4BN6A 3K6HA 3HZNA 1YKIA 4TTBA 3KWKA 5KRDA 2HAYA 3GR3A 1BKJA 4QLXA 2IFAA 1OONA 3BM2A 4XOOA 1KQDA 3OF4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5J6C A;  1VFR A;  1YLR A;  1IDT A;  3GB5 A;  4TTC A;  1ICV A;  3EO8 A;  3BEM A;  3E39 A;  2WZV A;  2FRE A;  3X22 A;  4QLY A;  1DS7 A;  4XOM A;  4DN2 A;  4EO3 A;  3E10 A;  3GE5 A;  3TO0 A;  2I7H A;  3H4O A;  3PXV A;  1OOQ A;  2WQF A;  3GE6 A;  1ICU A;  1NEC A;  3GFD A;  5KO7 A;  4BN7 A;  4BN8 A;  4XOQ A;  1KQB A;  1OO5 A;  1VKW A;  3TNZ A;  4URP A;  1V5Y A;  1F5V A;  3BM1 A;  1KQC A;  3GAG A;  1ZCH A;  1OO6 A;  2B67 A;  4BN9 A;  2BKJ A;  3QDL A;  3M5K A;  1YWQ A;  2ISJ A;  2ISK A;  3EK3 A;  3EO7 A;  5KO8 A;  3N2S A;  4BNB A;  2YMV A;  3EOF A;  5HEI A;  3X21 A;  1ICR A;  1YLU A;  1V5Z A;  3GBH A;  2WZW A;  2ISL A;  3HOI A;  3GFA A;  4G8S A;  1NOX A;  2R01 A;  3GH8 A;  3KOQ A;  3HJ9 A;  3G14 A;  2H0U A;  5HDJ A;  4BN6 A;  3K6H A;  3HZN A;  1YKI A;  4TTB A;  3KWK A;  5KRD A;  2HAY A;  3GR3 A;  1BKJ A;  4QLX A;  2IFA A;  1OON A;  3BM2 A;  4XOO A;  1KQD A;  3OF4 A; 
#chains in the Genus database with same CATH topology
 5J6C A;  1VFR A;  1YLR A;  1IDT A;  3GB5 A;  4TTC A;  1ICV A;  3EO8 A;  3BEM A;  3E39 A;  2WZV A;  2FRE A;  3X22 A;  4QLY A;  1DS7 A;  4XOM A;  4DN2 A;  4EO3 A;  3E10 A;  3GE5 A;  3TO0 A;  2I7H A;  3H4O A;  3PXV A;  1OOQ A;  2WQF A;  3GE6 A;  1ICU A;  1NEC A;  3GFD A;  5KO7 A;  4BN7 A;  4BN8 A;  1J6R A;  4XOQ A;  1KQB A;  1OO5 A;  1VKW A;  3TNZ A;  1V5Y A;  4URP A;  1F5V A;  3BM1 A;  1KQC A;  3GAG A;  1ZCH A;  1OO6 A;  2B67 A;  4BN9 A;  2BKJ A;  3QDL A;  3M5K A;  1YWQ A;  2ISJ A;  2ISK A;  3EK3 A;  3EO7 A;  5KO8 A;  3N2S A;  4BNB A;  2YMV A;  3EOF A;  5HEI A;  3X21 A;  1ICR A;  1YLU A;  1V5Z A;  3GBH A;  2WZW A;  2ISL A;  3HOI A;  3GFA A;  4G8S A;  1NOX A;  2R01 A;  3GH8 A;  3KOQ A;  3HJ9 A;  3G14 A;  2H0U A;  5HDJ A;  4BN6 A;  3K6H A;  3HZN A;  1YKI A;  4TTB A;  3KWK A;  5KRD A;  2HAY A;  3GR3 A;  1BKJ A;  4QLX A;  2IFA A;  1OON A;  3BM2 A;  4XOO A;  1KQD A;  3OF4 A; 
#chains in the Genus database with same CATH homology
 5J6C A;  1VFR A;  1YLR A;  1IDT A;  3GB5 A;  4TTC A;  1ICV A;  3EO8 A;  3BEM A;  3E39 A;  2WZV A;  2FRE A;  3X22 A;  4QLY A;  1DS7 A;  4XOM A;  4DN2 A;  4EO3 A;  3E10 A;  3GE5 A;  3TO0 A;  2I7H A;  3H4O A;  3PXV A;  1OOQ A;  2WQF A;  3GE6 A;  1ICU A;  1NEC A;  3GFD A;  5KO7 A;  4BN7 A;  4BN8 A;  1J6R A;  4XOQ A;  1KQB A;  1OO5 A;  1VKW A;  3TNZ A;  1V5Y A;  4URP A;  1F5V A;  3BM1 A;  1KQC A;  3GAG A;  1ZCH A;  1OO6 A;  2B67 A;  4BN9 A;  2BKJ A;  3QDL A;  3M5K A;  1YWQ A;  2ISJ A;  2ISK A;  3EK3 A;  3EO7 A;  5KO8 A;  3N2S A;  4BNB A;  2YMV A;  3EOF A;  5HEI A;  3X21 A;  1ICR A;  1YLU A;  1V5Z A;  3GBH A;  2WZW A;  2ISL A;  3HOI A;  3GFA A;  4G8S A;  1NOX A;  2R01 A;  3GH8 A;  3KOQ A;  3HJ9 A;  3G14 A;  2H0U A;  5HDJ A;  4BN6 A;  3K6H A;  3HZN A;  1YKI A;  4TTB A;  3KWK A;  5KRD A;  2HAY A;  3GR3 A;  1BKJ A;  4QLX A;  2IFA A;  1OON A;  3BM2 A;  4XOO A;  1KQD A;  3OF4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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