3GFDA

Crystal structure of mus musculus iodotyrosine deiodinase (iyd) bound to fmn and mono-iodotyrosine (mit)
Total Genus 60
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
222
structure length
220
Chain Sequence
SVEHIPFSHTRYPEQEMRMRSQEFYELLNKRRSVRFISSEHVPMEVIENVIKAAGTAPSGAHTEPWTFVVVKDPDMKHKIREIIEEEEEINYMKRMGKRWVTDLKKLRTNWIKEYLDTAPVLILIFKQVHGFNGKKKVHYYNEISVSIACGLLLAALQNAGLVTVTTTPLNCGPRLRVLLGRPSHEKLLVLLPVGYPSRDATVPDLKRKALDQIMVTVHH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Mus musculus
molecule keywords Iodotyrosine dehalogenase 1
total genus 60
structure length 220
sequence length 222
chains with identical sequence B
ec nomenclature ec 1.21.1.1: Iodotyrosine deiodinase.
pdb deposition date 2009-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00881 Nitroreductase Nitroreductase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.109.10 Alpha Beta 3-Layer(aba) Sandwich NADH Oxidase NADH Oxidase 3gfdA01
4EO3A 1KQBA 3M5KA 3E10A 1VFRA 3BEMA 3KOQA 3H4OA 2YMVA 3GBHA 4G8SA 2BKJA 2I7HA 3GAGA 3OF4A 3GFDA 2IFAA 3HZNA 4TTCA 5KO8A 2R01A 3GR3A 3GFAA 4BN9A 4TTBA 4XOMA 3PXVA 1ZCHA 1KQCA 2B67A 1V5ZA 3GE5A 4DN2A 3BM1A 3EO8A 3K6HA 4BN6A 1V5YA 3GH8A 3TNZA 3TO0A 1DS7A 1YLRA 2ISLA 1OONA 2WZVA 1OO5A 3QDLA 1YKIA 3X22A 1NECA 2WQFA 4BN8A 3KWKA 1YLUA 5HEIA 4BN7A 5J6CA 1IDTA 3HOIA 3X21A 1ICUA 1ICVA 4QLXA 1YWQA 3EO7A 5KRDA 4BNBA 1NOXA 1OO6A 3E39A 4XOQA 2ISJA 2HAYA 3EK3A 2H0UA 3EOFA 2ISKA 5HDJA 2FREA 3GE6A 1BKJA 3HJ9A 1ICRA 3G14A 5KO7A 2WZWA 3GB5A 1OOQA 1KQDA 4XOOA 3N2SA 1VKWA 3BM2A 4QLYA 1F5VA 4URPA
chains in the Genus database with same CATH superfamily
4EO3A 1KQBA 3M5KA 3E10A 1VFRA 3BEMA 3KOQA 3H4OA 2YMVA 3GBHA 4G8SA 2BKJA 2I7HA 3GAGA 3OF4A 3GFDA 2IFAA 3HZNA 4TTCA 5KO8A 2R01A 3GR3A 3GFAA 4BN9A 4TTBA 4XOMA 3PXVA 1ZCHA 1KQCA 2B67A 1V5ZA 3GE5A 4DN2A 3BM1A 3EO8A 3K6HA 4BN6A 1V5YA 3GH8A 3TNZA 3TO0A 1J6RA 1DS7A 1YLRA 2ISLA 1OONA 2WZVA 1OO5A 3QDLA 1YKIA 3X22A 1NECA 2WQFA 4BN8A 3KWKA 1YLUA 5HEIA 4BN7A 5J6CA 1IDTA 3HOIA 3X21A 1ICUA 1ICVA 4QLXA 1YWQA 3EO7A 5KRDA 4BNBA 1NOXA 1OO6A 3E39A 4XOQA 2ISJA 2HAYA 3EK3A 2H0UA 3EOFA 2ISKA 5HDJA 2FREA 3GE6A 1BKJA 3HJ9A 1ICRA 3G14A 5KO7A 2WZWA 3GB5A 1OOQA 1KQDA 4XOOA 3N2SA 1VKWA 3BM2A 4QLYA 1F5VA 4URPA
chains in the Genus database with same CATH topology
4EO3A 1KQBA 3M5KA 3E10A 1VFRA 3BEMA 3KOQA 3H4OA 2YMVA 3GBHA 4G8SA 2BKJA 2I7HA 3GAGA 3OF4A 3GFDA 2IFAA 3HZNA 4TTCA 5KO8A 2R01A 3GR3A 3GFAA 4BN9A 4TTBA 4XOMA 3PXVA 1ZCHA 1KQCA 2B67A 1V5ZA 3GE5A 4DN2A 3BM1A 3EO8A 3K6HA 4BN6A 1V5YA 3GH8A 3TNZA 3TO0A 1J6RA 1DS7A 1YLRA 2ISLA 1OONA 2WZVA 1OO5A 3QDLA 1YKIA 3X22A 1NECA 2WQFA 4BN8A 3KWKA 1YLUA 5HEIA 4BN7A 5J6CA 1IDTA 3HOIA 3X21A 1ICUA 1ICVA 4QLXA 1YWQA 3EO7A 5KRDA 4BNBA 1NOXA 1OO6A 3E39A 4XOQA 2ISJA 2HAYA 3EK3A 2H0UA 3EOFA 2ISKA 5HDJA 2FREA 3GE6A 1BKJA 3HJ9A 1ICRA 3G14A 5KO7A 2WZWA 3GB5A 1OOQA 1KQDA 4XOOA 3N2SA 1VKWA 3BM2A 4QLYA 1F5VA 4URPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EO3 A;  1KQB A;  3M5K A;  3E10 A;  1VFR A;  3BEM A;  3KOQ A;  3H4O A;  2YMV A;  3GBH A;  4G8S A;  2BKJ A;  2I7H A;  3GAG A;  3OF4 A;  3GFD A;  2IFA A;  3HZN A;  4TTC A;  5KO8 A;  2R01 A;  3GR3 A;  3GFA A;  4BN9 A;  4TTB A;  4XOM A;  3PXV A;  1ZCH A;  1KQC A;  2B67 A;  1V5Z A;  3GE5 A;  4DN2 A;  3BM1 A;  3EO8 A;  3K6H A;  4BN6 A;  1V5Y A;  3GH8 A;  3TNZ A;  3TO0 A;  1DS7 A;  1YLR A;  2ISL A;  1OON A;  2WZV A;  1OO5 A;  3QDL A;  1YKI A;  3X22 A;  1NEC A;  2WQF A;  4BN8 A;  3KWK A;  1YLU A;  5HEI A;  4BN7 A;  5J6C A;  1IDT A;  3HOI A;  3X21 A;  1ICU A;  1ICV A;  4QLX A;  1YWQ A;  3EO7 A;  5KRD A;  4BNB A;  1NOX A;  1OO6 A;  3E39 A;  4XOQ A;  2ISJ A;  2HAY A;  3EK3 A;  2H0U A;  3EOF A;  2ISK A;  5HDJ A;  2FRE A;  3GE6 A;  1BKJ A;  3HJ9 A;  1ICR A;  3G14 A;  5KO7 A;  2WZW A;  3GB5 A;  1OOQ A;  1KQD A;  4XOO A;  3N2S A;  1VKW A;  3BM2 A;  4QLY A;  1F5V A;  4URP A; 
#chains in the Genus database with same CATH topology
 4EO3 A;  1KQB A;  3M5K A;  3E10 A;  1VFR A;  3BEM A;  3KOQ A;  3H4O A;  2YMV A;  3GBH A;  4G8S A;  2BKJ A;  2I7H A;  3GAG A;  3OF4 A;  3GFD A;  2IFA A;  3HZN A;  4TTC A;  5KO8 A;  2R01 A;  3GR3 A;  3GFA A;  4BN9 A;  4TTB A;  4XOM A;  3PXV A;  1ZCH A;  1KQC A;  2B67 A;  1V5Z A;  3GE5 A;  4DN2 A;  3BM1 A;  3EO8 A;  3K6H A;  4BN6 A;  1V5Y A;  3GH8 A;  3TNZ A;  3TO0 A;  1J6R A;  1DS7 A;  1YLR A;  2ISL A;  1OON A;  2WZV A;  1OO5 A;  3QDL A;  1YKI A;  3X22 A;  1NEC A;  2WQF A;  4BN8 A;  3KWK A;  1YLU A;  5HEI A;  4BN7 A;  5J6C A;  1IDT A;  3HOI A;  3X21 A;  1ICU A;  1ICV A;  4QLX A;  1YWQ A;  3EO7 A;  5KRD A;  4BNB A;  1NOX A;  1OO6 A;  3E39 A;  4XOQ A;  2ISJ A;  2HAY A;  3EK3 A;  2H0U A;  3EOF A;  2ISK A;  5HDJ A;  2FRE A;  3GE6 A;  1BKJ A;  3HJ9 A;  1ICR A;  3G14 A;  5KO7 A;  2WZW A;  3GB5 A;  1OOQ A;  1KQD A;  4XOO A;  3N2S A;  1VKW A;  3BM2 A;  4QLY A;  1F5V A;  4URP A; 
#chains in the Genus database with same CATH homology
 4EO3 A;  1KQB A;  3M5K A;  3E10 A;  1VFR A;  3BEM A;  3KOQ A;  3H4O A;  2YMV A;  3GBH A;  4G8S A;  2BKJ A;  2I7H A;  3GAG A;  3OF4 A;  3GFD A;  2IFA A;  3HZN A;  4TTC A;  5KO8 A;  2R01 A;  3GR3 A;  3GFA A;  4BN9 A;  4TTB A;  4XOM A;  3PXV A;  1ZCH A;  1KQC A;  2B67 A;  1V5Z A;  3GE5 A;  4DN2 A;  3BM1 A;  3EO8 A;  3K6H A;  4BN6 A;  1V5Y A;  3GH8 A;  3TNZ A;  3TO0 A;  1J6R A;  1DS7 A;  1YLR A;  2ISL A;  1OON A;  2WZV A;  1OO5 A;  3QDL A;  1YKI A;  3X22 A;  1NEC A;  2WQF A;  4BN8 A;  3KWK A;  1YLU A;  5HEI A;  4BN7 A;  5J6C A;  1IDT A;  3HOI A;  3X21 A;  1ICU A;  1ICV A;  4QLX A;  1YWQ A;  3EO7 A;  5KRD A;  4BNB A;  1NOX A;  1OO6 A;  3E39 A;  4XOQ A;  2ISJ A;  2HAY A;  3EK3 A;  2H0U A;  3EOF A;  2ISK A;  5HDJ A;  2FRE A;  3GE6 A;  1BKJ A;  3HJ9 A;  1ICR A;  3G14 A;  5KO7 A;  2WZW A;  3GB5 A;  1OOQ A;  1KQD A;  4XOO A;  3N2S A;  1VKW A;  3BM2 A;  4QLY A;  1F5V A;  4URP A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...