3GH8A

Crystal structure of mus musculus iodotyrosine deiodinase (iyd) bound to fmn and di-iodotyrosine (dit)
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
221
structure length
221
Chain Sequence
SVEHIPFSHTRYPEQEMRMRSQEFYELLNKRRSVRFISSEHVPMEVIENVIKAAGTAPSGAHTEPWTFVVVKDPDMKHKIREIIEEEEEINYMKRMGKRWVTDLKKLRTNWIKEYLDTAPVLILIFKQVHGFAANGKKKVHYYNEISVSIACGLLLAALQNAGLVTVTTTPLNCGPRLRVLLGRPSHEKLLVLLPVGYPSRDATVPDLKRKALDQIMVTVH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Mus musculus
molecule keywords Iodotyrosine dehalogenase 1
total genus 58
structure length 221
sequence length 221
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 1.21.1.1: Iodotyrosine deiodinase.
pdb deposition date 2009-03-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00881 Nitroreductase Nitroreductase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.109.10 Alpha Beta 3-Layer(aba) Sandwich NADH Oxidase NADH Oxidase 3gh8A01
3X21A 1KQDA 2H0UA 3HOIA 3GH8A 3HZNA 4QLXA 3E39A 3GE6A 1OO6A 3GFAA 2B67A 1ICRA 4BN9A 3BM1A 4XOQA 4BN6A 3TO0A 4TTBA 1ICUA 2WZVA 1ICVA 3QDLA 5HEIA 4G8SA 1OOQA 3GAGA 2I7HA 3EO8A 4TTCA 2ISJA 3H4OA 3K6HA 4URPA 2ISKA 1OO5A 4XOMA 3OF4A 1NECA 3HJ9A 3KWKA 1NOXA 3GBHA 2IFAA 1YWQA 3TNZA 5J6CA 3EOFA 4EO3A 1KQCA 5KO8A 2FREA 1IDTA 1V5YA 2ISLA 3GR3A 1YLUA 5KO7A 2R01A 4XOOA 1VKWA 4BN7A 3M5KA 1OONA 3BEMA 2HAYA 3G14A 3EO7A 1KQBA 1DS7A 4BN8A 5KRDA 1YLRA 1F5VA 2WZWA 2WQFA 1YKIA 4DN2A 4BNBA 3PXVA 3KOQA 3X22A 1ZCHA 3GFDA 1VFRA 3N2SA 2YMVA 3GE5A 3EK3A 5HDJA 3GB5A 4QLYA 2BKJA 1V5ZA 3BM2A 1BKJA 3E10A
chains in the Genus database with same CATH superfamily
3X21A 1KQDA 2H0UA 3HOIA 3GH8A 3HZNA 4QLXA 3E39A 3GE6A 1OO6A 3GFAA 2B67A 1ICRA 4BN9A 3BM1A 4XOQA 4BN6A 3TO0A 4TTBA 1ICUA 2WZVA 1J6RA 1ICVA 3QDLA 5HEIA 4G8SA 1OOQA 3GAGA 2I7HA 3EO8A 4TTCA 2ISJA 3H4OA 3K6HA 4URPA 2ISKA 1OO5A 4XOMA 3OF4A 1NECA 3HJ9A 3KWKA 1NOXA 3GBHA 2IFAA 1YWQA 3TNZA 5J6CA 3EOFA 4EO3A 1KQCA 5KO8A 2FREA 1IDTA 1V5YA 2ISLA 3GR3A 1YLUA 5KO7A 2R01A 4XOOA 1VKWA 4BN7A 3M5KA 1OONA 3BEMA 2HAYA 3G14A 3EO7A 1KQBA 1DS7A 4BN8A 5KRDA 1YLRA 1F5VA 2WZWA 2WQFA 1YKIA 4DN2A 4BNBA 3PXVA 3KOQA 3X22A 1ZCHA 3GFDA 1VFRA 3N2SA 2YMVA 3GE5A 3EK3A 5HDJA 3GB5A 4QLYA 2BKJA 1V5ZA 3BM2A 1BKJA 3E10A
chains in the Genus database with same CATH topology
3X21A 1KQDA 2H0UA 3HOIA 3GH8A 3HZNA 4QLXA 3E39A 3GE6A 1OO6A 3GFAA 2B67A 1ICRA 4BN9A 3BM1A 4XOQA 4BN6A 3TO0A 4TTBA 1ICUA 2WZVA 1J6RA 1ICVA 3QDLA 5HEIA 4G8SA 1OOQA 3GAGA 2I7HA 3EO8A 4TTCA 2ISJA 3H4OA 3K6HA 4URPA 2ISKA 1OO5A 4XOMA 3OF4A 1NECA 3HJ9A 3KWKA 1NOXA 3GBHA 2IFAA 1YWQA 3TNZA 5J6CA 3EOFA 4EO3A 1KQCA 5KO8A 2FREA 1IDTA 1V5YA 2ISLA 3GR3A 1YLUA 5KO7A 2R01A 4XOOA 1VKWA 4BN7A 3M5KA 1OONA 3BEMA 2HAYA 3G14A 3EO7A 1KQBA 1DS7A 4BN8A 5KRDA 1YLRA 1F5VA 2WZWA 2WQFA 1YKIA 4DN2A 4BNBA 3PXVA 3KOQA 3X22A 1ZCHA 3GFDA 1VFRA 3N2SA 2YMVA 3GE5A 3EK3A 5HDJA 3GB5A 4QLYA 2BKJA 1V5ZA 3BM2A 1BKJA 3E10A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3X21 A;  1KQD A;  2H0U A;  3HOI A;  3GH8 A;  3HZN A;  4QLX A;  3E39 A;  3GE6 A;  1OO6 A;  3GFA A;  2B67 A;  1ICR A;  4BN9 A;  3BM1 A;  4XOQ A;  4BN6 A;  3TO0 A;  4TTB A;  1ICU A;  2WZV A;  1ICV A;  3QDL A;  5HEI A;  4G8S A;  1OOQ A;  3GAG A;  2I7H A;  3EO8 A;  4TTC A;  2ISJ A;  3H4O A;  3K6H A;  4URP A;  2ISK A;  1OO5 A;  4XOM A;  3OF4 A;  1NEC A;  3HJ9 A;  3KWK A;  1NOX A;  3GBH A;  2IFA A;  1YWQ A;  3TNZ A;  5J6C A;  3EOF A;  4EO3 A;  1KQC A;  5KO8 A;  2FRE A;  1IDT A;  1V5Y A;  2ISL A;  3GR3 A;  1YLU A;  5KO7 A;  2R01 A;  4XOO A;  1VKW A;  4BN7 A;  3M5K A;  1OON A;  3BEM A;  2HAY A;  3G14 A;  3EO7 A;  1KQB A;  1DS7 A;  4BN8 A;  5KRD A;  1YLR A;  1F5V A;  2WZW A;  2WQF A;  1YKI A;  4DN2 A;  4BNB A;  3PXV A;  3KOQ A;  3X22 A;  1ZCH A;  3GFD A;  1VFR A;  3N2S A;  2YMV A;  3GE5 A;  3EK3 A;  5HDJ A;  3GB5 A;  4QLY A;  2BKJ A;  1V5Z A;  3BM2 A;  1BKJ A;  3E10 A; 
#chains in the Genus database with same CATH topology
 3X21 A;  1KQD A;  2H0U A;  3HOI A;  3GH8 A;  3HZN A;  4QLX A;  3E39 A;  3GE6 A;  1OO6 A;  3GFA A;  2B67 A;  1ICR A;  4BN9 A;  3BM1 A;  4XOQ A;  4BN6 A;  3TO0 A;  4TTB A;  1ICU A;  2WZV A;  1J6R A;  1ICV A;  3QDL A;  5HEI A;  4G8S A;  1OOQ A;  3GAG A;  2I7H A;  3EO8 A;  4TTC A;  2ISJ A;  3H4O A;  3K6H A;  4URP A;  2ISK A;  1OO5 A;  4XOM A;  3OF4 A;  1NEC A;  3HJ9 A;  3KWK A;  1NOX A;  3GBH A;  2IFA A;  1YWQ A;  3TNZ A;  5J6C A;  3EOF A;  4EO3 A;  1KQC A;  5KO8 A;  2FRE A;  1IDT A;  1V5Y A;  2ISL A;  3GR3 A;  1YLU A;  5KO7 A;  2R01 A;  4XOO A;  1VKW A;  4BN7 A;  3M5K A;  1OON A;  3BEM A;  2HAY A;  3G14 A;  3EO7 A;  1KQB A;  1DS7 A;  4BN8 A;  5KRD A;  1YLR A;  1F5V A;  2WZW A;  2WQF A;  1YKI A;  4DN2 A;  4BNB A;  3PXV A;  3KOQ A;  3X22 A;  1ZCH A;  3GFD A;  1VFR A;  3N2S A;  2YMV A;  3GE5 A;  3EK3 A;  5HDJ A;  3GB5 A;  4QLY A;  2BKJ A;  1V5Z A;  3BM2 A;  1BKJ A;  3E10 A; 
#chains in the Genus database with same CATH homology
 3X21 A;  1KQD A;  2H0U A;  3HOI A;  3GH8 A;  3HZN A;  4QLX A;  3E39 A;  3GE6 A;  1OO6 A;  3GFA A;  2B67 A;  1ICR A;  4BN9 A;  3BM1 A;  4XOQ A;  4BN6 A;  3TO0 A;  4TTB A;  1ICU A;  2WZV A;  1J6R A;  1ICV A;  3QDL A;  5HEI A;  4G8S A;  1OOQ A;  3GAG A;  2I7H A;  3EO8 A;  4TTC A;  2ISJ A;  3H4O A;  3K6H A;  4URP A;  2ISK A;  1OO5 A;  4XOM A;  3OF4 A;  1NEC A;  3HJ9 A;  3KWK A;  1NOX A;  3GBH A;  2IFA A;  1YWQ A;  3TNZ A;  5J6C A;  3EOF A;  4EO3 A;  1KQC A;  5KO8 A;  2FRE A;  1IDT A;  1V5Y A;  2ISL A;  3GR3 A;  1YLU A;  5KO7 A;  2R01 A;  4XOO A;  1VKW A;  4BN7 A;  3M5K A;  1OON A;  3BEM A;  2HAY A;  3G14 A;  3EO7 A;  1KQB A;  1DS7 A;  4BN8 A;  5KRD A;  1YLR A;  1F5V A;  2WZW A;  2WQF A;  1YKI A;  4DN2 A;  4BNB A;  3PXV A;  3KOQ A;  3X22 A;  1ZCH A;  3GFD A;  1VFR A;  3N2S A;  2YMV A;  3GE5 A;  3EK3 A;  5HDJ A;  3GB5 A;  4QLY A;  2BKJ A;  1V5Z A;  3BM2 A;  1BKJ A;  3E10 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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