3GH8A

Crystal structure of mus musculus iodotyrosine deiodinase (iyd) bound to fmn and di-iodotyrosine (dit)
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
221
structure length
221
Chain Sequence
SVEHIPFSHTRYPEQEMRMRSQEFYELLNKRRSVRFISSEHVPMEVIENVIKAAGTAPSGAHTEPWTFVVVKDPDMKHKIREIIEEEEEINYMKRMGKRWVTDLKKLRTNWIKEYLDTAPVLILIFKQVHGFAANGKKKVHYYNEISVSIACGLLLAALQNAGLVTVTTTPLNCGPRLRVLLGRPSHEKLLVLLPVGYPSRDATVPDLKRKALDQIMVTVH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
source organism Mus musculus
publication title Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands.
pubmed doi rcsb
molecule keywords Iodotyrosine dehalogenase 1
total genus 58
structure length 221
sequence length 221
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 1.21.1.1: Iodotyrosine deiodinase.
pdb deposition date 2009-03-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00881 Nitroreductase Nitroreductase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.109.10 Alpha Beta 3-Layer(aba) Sandwich NADH Oxidase NADH Oxidase 3gh8A01
1VFRA 5J6CA 2ISKA 1YWQA 1OOQA 3EO8A 4TTCA 5KRDA 3HJ9A 4XOOA 2WZWA 2WZVA 1KQCA 1V5ZA 3N2SA 5HEIA 3E10A 3EO7A 4QLXA 4BN6A 1YLUA 2BKJA 3KWKA 1DS7A 2WQFA 2HAYA 5KO7A 1BKJA 1VKWA 1NECA 1YLRA 2R01A 1YKIA 3BEMA 2B67A 1ICRA 3HOIA 2ISLA 3M5KA 3BM2A 3QDLA 3K6HA 1ZCHA 3TO0A 4BNBA 1OONA 1KQBA 4URPA 1F5VA 1V5YA 3G14A 3GE6A 3GFDA 3E39A 4XOMA 5HDJA 3GBHA 1ICVA 4BN9A 3GFAA 5KO8A 1KQDA 3OF4A 4EO3A 3TNZA 4QLYA 3X22A 3PXVA 3X21A 3HZNA 3GB5A 4DN2A 4XOQA 4BN8A 2IFAA 2ISJA 3KOQA 3GE5A 1OO5A 2FREA 3EK3A 1OO6A 3EOFA 2H0UA 2YMVA 4TTBA 4BN7A 4G8SA 3GR3A 1IDTA 3GAGA 3BM1A 2I7HA 3H4OA 1ICUA 1NOXA 3GH8A
chains in the Genus database with same CATH superfamily
1VFRA 5J6CA 2ISKA 1YWQA 1OOQA 3EO8A 4TTCA 5KRDA 3HJ9A 4XOOA 2WZWA 2WZVA 1KQCA 1V5ZA 3N2SA 5HEIA 3E10A 1J6RA 3EO7A 4QLXA 4BN6A 1YLUA 2BKJA 3KWKA 1DS7A 2WQFA 2HAYA 5KO7A 1BKJA 1VKWA 1NECA 1YLRA 2R01A 1YKIA 3BEMA 2B67A 1ICRA 3HOIA 2ISLA 3M5KA 3BM2A 3QDLA 3K6HA 1ZCHA 3TO0A 4BNBA 1OONA 1KQBA 4URPA 1F5VA 1V5YA 3G14A 3GE6A 3GFDA 3E39A 4XOMA 5HDJA 3GBHA 1ICVA 4BN9A 3GFAA 5KO8A 1KQDA 3OF4A 4EO3A 3TNZA 4QLYA 3X22A 3PXVA 3X21A 3HZNA 3GB5A 4DN2A 4XOQA 4BN8A 2IFAA 2ISJA 3KOQA 3GE5A 1OO5A 2FREA 3EK3A 1OO6A 3EOFA 2H0UA 2YMVA 4TTBA 4BN7A 4G8SA 3GR3A 1IDTA 3GAGA 3BM1A 2I7HA 3H4OA 1ICUA 1NOXA 3GH8A
chains in the Genus database with same CATH topology
1VFRA 5J6CA 2ISKA 1YWQA 1OOQA 3EO8A 4TTCA 5KRDA 3HJ9A 4XOOA 2WZWA 2WZVA 1KQCA 1V5ZA 3N2SA 5HEIA 3E10A 1J6RA 3EO7A 4QLXA 4BN6A 1YLUA 2BKJA 3KWKA 1DS7A 2WQFA 2HAYA 5KO7A 1BKJA 1VKWA 1NECA 1YLRA 2R01A 1YKIA 3BEMA 2B67A 1ICRA 3HOIA 2ISLA 3M5KA 3BM2A 3QDLA 3K6HA 1ZCHA 3TO0A 4BNBA 1OONA 1KQBA 4URPA 1F5VA 1V5YA 3G14A 3GE6A 3GFDA 3E39A 4XOMA 5HDJA 3GBHA 1ICVA 4BN9A 3GFAA 5KO8A 1KQDA 3OF4A 4EO3A 3TNZA 4QLYA 3X22A 3PXVA 3X21A 3HZNA 3GB5A 4DN2A 4XOQA 4BN8A 2IFAA 2ISJA 3KOQA 3GE5A 1OO5A 2FREA 3EK3A 1OO6A 3EOFA 2H0UA 2YMVA 4TTBA 4BN7A 4G8SA 3GR3A 1IDTA 3GAGA 3BM1A 2I7HA 3H4OA 1ICUA 1NOXA 3GH8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VFR A;  5J6C A;  2ISK A;  1YWQ A;  1OOQ A;  3EO8 A;  4TTC A;  5KRD A;  3HJ9 A;  4XOO A;  2WZW A;  2WZV A;  1KQC A;  1V5Z A;  3N2S A;  5HEI A;  3E10 A;  3EO7 A;  4QLX A;  4BN6 A;  1YLU A;  2BKJ A;  3KWK A;  1DS7 A;  2WQF A;  2HAY A;  5KO7 A;  1BKJ A;  1VKW A;  1NEC A;  1YLR A;  2R01 A;  1YKI A;  3BEM A;  2B67 A;  1ICR A;  3HOI A;  2ISL A;  3M5K A;  3BM2 A;  3QDL A;  3K6H A;  1ZCH A;  3TO0 A;  4BNB A;  1OON A;  1KQB A;  4URP A;  1F5V A;  1V5Y A;  3G14 A;  3GE6 A;  3GFD A;  3E39 A;  4XOM A;  5HDJ A;  3GBH A;  1ICV A;  4BN9 A;  3GFA A;  5KO8 A;  1KQD A;  3OF4 A;  4EO3 A;  3TNZ A;  4QLY A;  3X22 A;  3PXV A;  3X21 A;  3HZN A;  3GB5 A;  4DN2 A;  4XOQ A;  4BN8 A;  2IFA A;  2ISJ A;  3KOQ A;  3GE5 A;  1OO5 A;  2FRE A;  3EK3 A;  1OO6 A;  3EOF A;  2H0U A;  2YMV A;  4TTB A;  4BN7 A;  4G8S A;  3GR3 A;  1IDT A;  3GAG A;  3BM1 A;  2I7H A;  3H4O A;  1ICU A;  1NOX A;  3GH8 A; 
#chains in the Genus database with same CATH topology
 1VFR A;  5J6C A;  2ISK A;  1YWQ A;  1OOQ A;  3EO8 A;  4TTC A;  5KRD A;  3HJ9 A;  4XOO A;  2WZW A;  2WZV A;  1KQC A;  1V5Z A;  3N2S A;  5HEI A;  3E10 A;  1J6R A;  3EO7 A;  4QLX A;  4BN6 A;  1YLU A;  2BKJ A;  3KWK A;  1DS7 A;  2WQF A;  2HAY A;  5KO7 A;  1BKJ A;  1VKW A;  1NEC A;  1YLR A;  2R01 A;  1YKI A;  3BEM A;  2B67 A;  1ICR A;  3HOI A;  2ISL A;  3M5K A;  3BM2 A;  3QDL A;  3K6H A;  1ZCH A;  3TO0 A;  4BNB A;  1OON A;  1KQB A;  4URP A;  1F5V A;  1V5Y A;  3G14 A;  3GE6 A;  3GFD A;  3E39 A;  4XOM A;  5HDJ A;  3GBH A;  1ICV A;  4BN9 A;  3GFA A;  5KO8 A;  1KQD A;  3OF4 A;  4EO3 A;  3TNZ A;  4QLY A;  3X22 A;  3PXV A;  3X21 A;  3HZN A;  3GB5 A;  4DN2 A;  4XOQ A;  4BN8 A;  2IFA A;  2ISJ A;  3KOQ A;  3GE5 A;  1OO5 A;  2FRE A;  3EK3 A;  1OO6 A;  3EOF A;  2H0U A;  2YMV A;  4TTB A;  4BN7 A;  4G8S A;  3GR3 A;  1IDT A;  3GAG A;  3BM1 A;  2I7H A;  3H4O A;  1ICU A;  1NOX A;  3GH8 A; 
#chains in the Genus database with same CATH homology
 1VFR A;  5J6C A;  2ISK A;  1YWQ A;  1OOQ A;  3EO8 A;  4TTC A;  5KRD A;  3HJ9 A;  4XOO A;  2WZW A;  2WZV A;  1KQC A;  1V5Z A;  3N2S A;  5HEI A;  3E10 A;  1J6R A;  3EO7 A;  4QLX A;  4BN6 A;  1YLU A;  2BKJ A;  3KWK A;  1DS7 A;  2WQF A;  2HAY A;  5KO7 A;  1BKJ A;  1VKW A;  1NEC A;  1YLR A;  2R01 A;  1YKI A;  3BEM A;  2B67 A;  1ICR A;  3HOI A;  2ISL A;  3M5K A;  3BM2 A;  3QDL A;  3K6H A;  1ZCH A;  3TO0 A;  4BNB A;  1OON A;  1KQB A;  4URP A;  1F5V A;  1V5Y A;  3G14 A;  3GE6 A;  3GFD A;  3E39 A;  4XOM A;  5HDJ A;  3GBH A;  1ICV A;  4BN9 A;  3GFA A;  5KO8 A;  1KQD A;  3OF4 A;  4EO3 A;  3TNZ A;  4QLY A;  3X22 A;  3PXV A;  3X21 A;  3HZN A;  3GB5 A;  4DN2 A;  4XOQ A;  4BN8 A;  2IFA A;  2ISJ A;  3KOQ A;  3GE5 A;  1OO5 A;  2FRE A;  3EK3 A;  1OO6 A;  3EOF A;  2H0U A;  2YMV A;  4TTB A;  4BN7 A;  4G8S A;  3GR3 A;  1IDT A;  3GAG A;  3BM1 A;  2I7H A;  3H4O A;  1ICU A;  1NOX A;  3GH8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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