3KRXG

Human grk2 in complex with gbetgamma subunits and balanol (co-crystal)
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
60
structure length
60
Chain Sequence
SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of human g protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol.
pubmed doi rcsb
molecule keywords Beta-adrenergic receptor kinase 1
molecule tags Protein binding
source organism Homo sapiens
total genus 13
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 2009-11-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 3krxG00
3PVWG 1B9XB 5HE0G 5HE3G 3V5WG 1B9YB 3PSCG 1OMWG 2PBIA 1TBGE 1XHMB 2TRCG 4PNKG 3SN6G 4KFMG 3AH8G 3PVUG 1GP2G 2BCJG 4MK0G 3CIKG 1A0RG 1GG2G 1GOTG 3KRWG 3KRXG 5HE1G 5TDHG 5KDOG 5HE2G
chains in the Genus database with same CATH superfamily
3PVWG 1B9XB 5HE0G 1HFES 1IOJA 5HE3G 3V5WG 1B9YB 3PSCG 1OMWG 2PBIA 1TBGE 1XHMB 2TRCG 4PNKG 3SN6G 4KFMG 3AH8G 3PVUG 1GP2G 2BCJG 4MK0G 3CIKG 1A0RG 1GG2G 1GOTG 3KRWG 3KRXG 5HE1G 5TDHG 5KDOG 5HE2G
chains in the Genus database with same CATH topology
3PVWG 1B9XB 5HE0G 5HE3G 3V5WG 1B9YB 3PSCG 1OMWG 2PBIA 1TBGE 1XHMB 2TRCG 4PNKG 3SN6G 4KFMG 3AH8G 3PVUG 1GP2G 2BCJG 4MK0G 3CIKG 1A0RG 1GG2G 1GOTG 3KRWG 3KRXG 5HE1G 5TDHG 5KDOG 5HE2G
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PVW G;  1B9X B;  5HE0 G;  5HE3 G;  3V5W G;  1B9Y B;  3PSC G;  1OMW G;  2PBI A;  1TBG E;  1XHM B;  2TRC G;  4PNK G;  3SN6 G;  4KFM G;  3AH8 G;  3PVU G;  1GP2 G;  2BCJ G;  4MK0 G;  3CIK G;  1A0R G;  1GG2 G;  1GOT G;  3KRW G;  3KRX G;  5HE1 G;  5TDH G;  5KDO G;  5HE2 G; 
#chains in the Genus database with same CATH topology
 3PVW G;  1B9X B;  5HE0 G;  1HFE S;  1IOJ A;  5HE3 G;  3V5W G;  1B9Y B;  3PSC G;  1OMW G;  2PBI A;  1TBG E;  1XHM B;  2TRC G;  4PNK G;  3SN6 G;  4KFM G;  3AH8 G;  3PVU G;  1GP2 G;  2BCJ G;  4MK0 G;  3CIK G;  1A0R G;  1GG2 G;  1GOT G;  3KRW G;  3KRX G;  5HE1 G;  5TDH G;  5KDO G;  5HE2 G; 
#chains in the Genus database with same CATH homology
 3PVW G;  1B9X B;  5HE0 G;  5HE3 G;  3V5W G;  1B9Y B;  3PSC G;  1OMW G;  2PBI A;  1TBG E;  1XHM B;  2TRC G;  4PNK G;  3SN6 G;  4KFM G;  3AH8 G;  3PVU G;  1GP2 G;  2BCJ G;  4MK0 G;  3CIK G;  1A0R G;  1GG2 G;  1GOT G;  3KRW G;  3KRX G;  5HE1 G;  5TDH G;  5KDO G;  5HE2 G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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