3KRXG

Human grk2 in complex with gbetgamma subunits and balanol (co-crystal)
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
60
structure length
60
Chain Sequence
SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure of human g protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Beta-adrenergic receptor kinase 1
total genus 13
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 2009-11-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 3krxG00
5HE2G 1TBGE 5HE1G 5HE0G 3AH8G 1GP2G 4KFMG 3KRXG 3PSCG 3PVUG 3SN6G 1GOTG 4MK0G 3CIKG 1OMWG 5HE3G 1GG2G 2PBIA 2TRCG 5TDHG 1B9YB 1XHMB 3KRWG 4PNKG 5KDOG 3PVWG 1B9XB 3V5WG 2BCJG 1A0RG
chains in the Genus database with same CATH superfamily
5HE2G 1TBGE 5HE1G 5HE0G 3AH8G 1GP2G 4KFMG 3KRXG 3PSCG 1HFES 3PVUG 3SN6G 1GOTG 4MK0G 3CIKG 1OMWG 5HE3G 1GG2G 2PBIA 2TRCG 5TDHG 1IOJA 1B9YB 1XHMB 3KRWG 4PNKG 5KDOG 3PVWG 1B9XB 3V5WG 2BCJG 1A0RG
chains in the Genus database with same CATH topology
5HE2G 1TBGE 5HE1G 5HE0G 3AH8G 1GP2G 4KFMG 3KRXG 3PSCG 3PVUG 3SN6G 1GOTG 4MK0G 3CIKG 1OMWG 5HE3G 1GG2G 2PBIA 2TRCG 5TDHG 1B9YB 1XHMB 3KRWG 4PNKG 5KDOG 3PVWG 1B9XB 3V5WG 2BCJG 1A0RG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HE2 G;  1TBG E;  5HE1 G;  5HE0 G;  3AH8 G;  1GP2 G;  4KFM G;  3KRX G;  3PSC G;  3PVU G;  3SN6 G;  1GOT G;  4MK0 G;  3CIK G;  1OMW G;  5HE3 G;  1GG2 G;  2PBI A;  2TRC G;  5TDH G;  1B9Y B;  1XHM B;  3KRW G;  4PNK G;  5KDO G;  3PVW G;  1B9X B;  3V5W G;  2BCJ G;  1A0R G; 
#chains in the Genus database with same CATH topology
 5HE2 G;  1TBG E;  5HE1 G;  5HE0 G;  3AH8 G;  1GP2 G;  4KFM G;  3KRX G;  3PSC G;  1HFE S;  3PVU G;  3SN6 G;  1GOT G;  4MK0 G;  3CIK G;  1OMW G;  5HE3 G;  1GG2 G;  2PBI A;  2TRC G;  5TDH G;  1IOJ A;  1B9Y B;  1XHM B;  3KRW G;  4PNK G;  5KDO G;  3PVW G;  1B9X B;  3V5W G;  2BCJ G;  1A0R G; 
#chains in the Genus database with same CATH homology
 5HE2 G;  1TBG E;  5HE1 G;  5HE0 G;  3AH8 G;  1GP2 G;  4KFM G;  3KRX G;  3PSC G;  3PVU G;  3SN6 G;  1GOT G;  4MK0 G;  3CIK G;  1OMW G;  5HE3 G;  1GG2 G;  2PBI A;  2TRC G;  5TDH G;  1B9Y B;  1XHM B;  3KRW G;  4PNK G;  5KDO G;  3PVW G;  1B9X B;  3V5W G;  2BCJ G;  1A0R G; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...