3LKYA

Monomeric griffithsin with a single gly-ser insertion
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
123
structure length
123
Chain Sequence
SLTHRKFGGSGGSPFSGSGLSSIAVRSGSYLDAIIIDGVHHGGSGGNLSPTFTFGSGEYISNMTIRSGDYIDNISFETNMGRRFGPYGGSGGSANTLSNVKVIQINGSAGDYLDSLDIYYEQY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Griffithsia
molecule keywords Griffithsin
total genus 24
structure length 123
sequence length 123
ec nomenclature
pdb deposition date 2010-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01419 Jacalin Jacalin-like lectin domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.100.10.30 Mainly Beta Aligned Prism Vitelline Membrane Outer Layer Protein I, subunit A Jacalin-like lectin domain 3lkyA00
2HYQA 4AKCA 2GUCA 4GX7A 3LL0A 1J4UA 5J4XA 2GTYA 3O44A 2GUXA 3WOBA 5BN6E 1ZGRA 3AQGA 1C3MA 3R51A 1XXRA 1JOTA 3LLZA 1X1VA 4R6NA 3WOCA 2BMYA 1OUWA 4PIKA 3VY6A 1UGWC 1WS4A 1VBPA 4PIFA 3LKYA 3R52A 1WS5A 3MITA 3VZEA 1XEZA 1C3NA 3P8SA 4AKBA 3VZGA 3LL2A 1XXQA 5JM1A 3VY7A 4AK4A 4PITA 4R6RA 1KUJA 1VBOA 1UGXA 5AV7A 1WS5C 2BN0A 1PXDA 3APAA 1UH1A 2HYRA 4R6PA 2NUOA 1M26A 1J4TA 3R50A 3LLYA 5J51A 1TOQA 4R6OA 3MIVA 3LM1A 4DDNA 3VZFA 1TP8A 3MIUA 1C3KA 1UGYA 2GUDA 4PIUA 4AKDA 1J4SA 1WS4C 4MQ0A 1ZGSA 4R6QA 2BMZA 5J4TA 1UH0A 5EXGA 1KU8A 1UGWA 4WOGA 3LL1A 1JACA 1UGYC 5J50A 2JZ4A 2GUEA 2NU5A
chains in the Genus database with same CATH superfamily
2HYQA 3EB7A 4AKCA 2GUCA 4GX7A 3LL0A 1J4UA 5J4XA 2GTYA 3O44A 2GUXA 3WOBA 4ARXA 5BN6E 1ZGRA 3AQGA 1C3MA 3R51A 2C9KA 1XXRA 1JOTA 1CIYA 3LLZA 1X1VA 4R6NA 3WOCA 2BMYA 4QX0A 1OUWA 4PIKA 4D8MA 4ARYA 3VY6A 1UGWC 1WS4A 1VBPA 4PIFA 4QX3A 3LKYA 3R52A 1WS5A 3MITA 3VZEA 1XEZA 1C3NA 3P8SA 4AKBA 3TOWA 3VZGA 3LL2A 1XXQA 5JM1A 3VY7A 4W8JA 4AK4A 4PITA 4R6RA 1KUJA 1VBOA 1UGXA 1DLCA 5AV7A 1WS5C 2BN0A 4QX1A 1PXDA 3APAA 1UH1A 2HYRA 4R6PA 1JI6A 1W99A 2NUOA 1M26A 1J4TA 3R50A 3LLYA 5J51A 1TOQA 2QP2A 4R6OA 3MIVA 3LM1A 4DDNA 3VZFA 1TP8A 3MIUA 1C3KA 1UGYA 2GUDA 4PIUA 4AKDA 1J4SA 1WS4C 4MQ0A 1ZGSA 4R6QA 2BMZA 5J4TA 1UH0A 5EXGA 1KU8A 4MOAA 1UGWA 4WOGA 3LL1A 1JACA 4QX2A 1I5PA 1UGYC 5J50A 2JZ4A 2GUEA 1VMOA 2NU5A
chains in the Genus database with same CATH topology
2HYQA 4AKCA 2GUCA 4GX7A 3LL0A 1J4UA 5J4XA 2GTYA 3O44A 2GUXA 3WOBA 5BN6E 1ZGRA 3AQGA 1C3MA 3R51A 1XXRA 1JOTA 3LLZA 1X1VA 4R6NA 3WOCA 2BMYA 1OUWA 4PIKA 3VY6A 1UGWC 1WS4A 1VBPA 4PIFA 3LKYA 3R52A 1WS5A 3MITA 3VZEA 1XEZA 1C3NA 3P8SA 4AKBA 3VZGA 3LL2A 1XXQA 5JM1A 3VY7A 4AK4A 4PITA 4R6RA 1KUJA 1VBOA 1UGXA 5AV7A 1WS5C 2BN0A 1PXDA 3APAA 1UH1A 2HYRA 4R6PA 2NUOA 1M26A 1J4TA 3R50A 3LLYA 5J51A 1TOQA 4R6OA 3MIVA 3LM1A 4DDNA 3VZFA 1TP8A 3MIUA 1C3KA 1UGYA 2GUDA 4PIUA 4AKDA 1J4SA 1WS4C 4MQ0A 1ZGSA 4R6QA 2BMZA 5J4TA 1UH0A 5EXGA 1KU8A 1UGWA 4WOGA 3LL1A 1JACA 1UGYC 5J50A 2JZ4A 2GUEA 2NU5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HYQ A;  4AKC A;  2GUC A;  4GX7 A;  3LL0 A;  1J4U A;  5J4X A;  2GTY A;  3O44 A;  2GUX A;  3WOB A;  5BN6 E;  1ZGR A;  3AQG A;  1C3M A;  3R51 A;  1XXR A;  1JOT A;  3LLZ A;  1X1V A;  4R6N A;  3WOC A;  2BMY A;  1OUW A;  4PIK A;  3VY6 A;  1UGW C;  1WS4 A;  1VBP A;  4PIF A;  3LKY A;  3R52 A;  1WS5 A;  3MIT A;  3VZE A;  1XEZ A;  1C3N A;  3P8S A;  4AKB A;  3VZG A;  3LL2 A;  1XXQ A;  5JM1 A;  3VY7 A;  4AK4 A;  4PIT A;  4R6R A;  1KUJ A;  1VBO A;  1UGX A;  5AV7 A;  1WS5 C;  2BN0 A;  1PXD A;  3APA A;  1UH1 A;  2HYR A;  4R6P A;  2NUO A;  1M26 A;  1J4T A;  3R50 A;  3LLY A;  5J51 A;  1TOQ A;  4R6O A;  3MIV A;  3LM1 A;  4DDN A;  3VZF A;  1TP8 A;  3MIU A;  1C3K A;  1UGY A;  2GUD A;  4PIU A;  4AKD A;  1J4S A;  1WS4 C;  4MQ0 A;  1ZGS A;  4R6Q A;  2BMZ A;  5J4T A;  1UH0 A;  5EXG A;  1KU8 A;  1UGW A;  4WOG A;  3LL1 A;  1JAC A;  1UGY C;  5J50 A;  2JZ4 A;  2GUE A;  2NU5 A; 
#chains in the Genus database with same CATH topology
 2HYQ A;  3EB7 A;  4AKC A;  2GUC A;  4GX7 A;  3LL0 A;  1J4U A;  5J4X A;  2GTY A;  3O44 A;  2GUX A;  3WOB A;  4ARX A;  5BN6 E;  1ZGR A;  3AQG A;  1C3M A;  3R51 A;  2C9K A;  1XXR A;  1JOT A;  1CIY A;  3LLZ A;  1X1V A;  4R6N A;  3WOC A;  2BMY A;  4QX0 A;  1OUW A;  4PIK A;  4D8M A;  4ARY A;  3VY6 A;  1UGW C;  1WS4 A;  1VBP A;  4PIF A;  4QX3 A;  3LKY A;  3R52 A;  1WS5 A;  3MIT A;  3VZE A;  1XEZ A;  1C3N A;  3P8S A;  4AKB A;  3TOW A;  3VZG A;  3LL2 A;  1XXQ A;  5JM1 A;  3VY7 A;  4W8J A;  4AK4 A;  4PIT A;  4R6R A;  1KUJ A;  1VBO A;  1UGX A;  1DLC A;  5AV7 A;  1WS5 C;  2BN0 A;  4QX1 A;  1PXD A;  3APA A;  1UH1 A;  2HYR A;  4R6P A;  1JI6 A;  1W99 A;  2NUO A;  1M26 A;  1J4T A;  3R50 A;  3LLY A;  5J51 A;  1TOQ A;  2QP2 A;  4R6O A;  3MIV A;  3LM1 A;  4DDN A;  3VZF A;  1TP8 A;  3MIU A;  1C3K A;  1UGY A;  2GUD A;  4PIU A;  4AKD A;  1J4S A;  1WS4 C;  4MQ0 A;  1ZGS A;  4R6Q A;  2BMZ A;  5J4T A;  1UH0 A;  5EXG A;  1KU8 A;  4MOA A;  1UGW A;  4WOG A;  3LL1 A;  1JAC A;  4QX2 A;  1I5P A;  1UGY C;  5J50 A;  2JZ4 A;  2GUE A;  1VMO A;  2NU5 A; 
#chains in the Genus database with same CATH homology
 2HYQ A;  4AKC A;  2GUC A;  4GX7 A;  3LL0 A;  1J4U A;  5J4X A;  2GTY A;  3O44 A;  2GUX A;  3WOB A;  5BN6 E;  1ZGR A;  3AQG A;  1C3M A;  3R51 A;  1XXR A;  1JOT A;  3LLZ A;  1X1V A;  4R6N A;  3WOC A;  2BMY A;  1OUW A;  4PIK A;  3VY6 A;  1UGW C;  1WS4 A;  1VBP A;  4PIF A;  3LKY A;  3R52 A;  1WS5 A;  3MIT A;  3VZE A;  1XEZ A;  1C3N A;  3P8S A;  4AKB A;  3VZG A;  3LL2 A;  1XXQ A;  5JM1 A;  3VY7 A;  4AK4 A;  4PIT A;  4R6R A;  1KUJ A;  1VBO A;  1UGX A;  5AV7 A;  1WS5 C;  2BN0 A;  1PXD A;  3APA A;  1UH1 A;  2HYR A;  4R6P A;  2NUO A;  1M26 A;  1J4T A;  3R50 A;  3LLY A;  5J51 A;  1TOQ A;  4R6O A;  3MIV A;  3LM1 A;  4DDN A;  3VZF A;  1TP8 A;  3MIU A;  1C3K A;  1UGY A;  2GUD A;  4PIU A;  4AKD A;  1J4S A;  1WS4 C;  4MQ0 A;  1ZGS A;  4R6Q A;  2BMZ A;  5J4T A;  1UH0 A;  5EXG A;  1KU8 A;  1UGW A;  4WOG A;  3LL1 A;  1JAC A;  1UGY C;  5J50 A;  2JZ4 A;  2GUE A;  2NU5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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