3LL0A

Monomeric griffithsin with two gly-ser insertions
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
125
structure length
125
Chain Sequence
SLTHRKFGGSGGSPFSGSGSGLSSIAVRSGSYLDAIIIDGVHHGGSGGNLSPTFTFGSGEYISNMTIRSGDYIDNISFETNMGRRFGPYGGSGGSANTLSNVKVIQINGSAGDYLDSLDIYYEQY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Griffithsia
molecule keywords Griffithsin
total genus 23
structure length 125
sequence length 125
ec nomenclature
pdb deposition date 2010-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01419 Jacalin Jacalin-like lectin domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.100.10.30 Mainly Beta Aligned Prism Vitelline Membrane Outer Layer Protein I, subunit A Jacalin-like lectin domain 3ll0A00
1ZGRA 4R6PA 1TOQA 1ZGSA 3P8SA 2GTYA 5AV7A 3APAA 3LKYA 1UGYC 3VY7A 1X1VA 4R6QA 5J50A 2BMYA 3LL1A 5J4XA 4MQ0A 3LL0A 1TP8A 1UGYA 1UGXA 4AK4A 1OUWA 4WOGA 3WOCA 1UH0A 3LLYA 4PIUA 1J4SA 3O44A 1JOTA 1VBOA 2GUXA 3VZEA 4PIKA 1C3MA 1UH1A 1KUJA 3AQGA 1JACA 1WS5C 2NUOA 3VY6A 4DDNA 2JZ4A 5BN6E 3MITA 4AKBA 1WS5A 3R51A 3VZGA 3WOBA 5JM1A 1XXQA 2HYQA 2BMZA 5EXGA 4AKDA 1C3NA 1UGWC 1WS4C 1VBPA 4R6NA 4PIFA 2BN0A 1J4UA 4GX7A 1UGWA 1WS4A 5J51A 1C3KA 1XXRA 1XEZA 4R6OA 3R52A 1PXDA 3VZFA 5J4TA 1J4TA 2HYRA 2GUDA 3LLZA 3MIVA 4R6RA 4AKCA 2GUEA 1KU8A 3R50A 3LL2A 3MIUA 2NU5A 2GUCA 3LM1A 4PITA 1M26A
chains in the Genus database with same CATH superfamily
1ZGRA 3EB7A 4R6PA 1TOQA 1ZGSA 3P8SA 2GTYA 5AV7A 3APAA 3LKYA 1UGYC 3VY7A 1X1VA 4R6QA 5J50A 2BMYA 3LL1A 5J4XA 4MQ0A 3LL0A 1TP8A 1UGYA 1UGXA 4AK4A 1OUWA 4WOGA 3WOCA 1UH0A 4W8JA 3LLYA 4PIUA 1J4SA 3O44A 1JOTA 1VBOA 2GUXA 3VZEA 4PIKA 1C3MA 1KUJA 1UH1A 3AQGA 1I5PA 1JACA 1WS5C 2NUOA 4QX2A 3VY6A 4DDNA 2JZ4A 5BN6E 3MITA 4AKBA 1WS5A 4QX0A 4MOAA 3R51A 3VZGA 3WOBA 5JM1A 1XXQA 2HYQA 2BMZA 4D8MA 5EXGA 3TOWA 4AKDA 2C9KA 1C3NA 4QX1A 1UGWC 1WS4C 1VBPA 4R6NA 4PIFA 2BN0A 1J4UA 4GX7A 1UGWA 1WS4A 5J51A 1CIYA 4ARXA 1C3KA 2QP2A 1XXRA 1XEZA 1DLCA 4QX3A 4R6OA 3R52A 1PXDA 3VZFA 5J4TA 1J4TA 2HYRA 2GUDA 3LLZA 3MIVA 4R6RA 4AKCA 2GUEA 1JI6A 1KU8A 3R50A 3LL2A 3MIUA 1VMOA 1W99A 2NU5A 4ARYA 2GUCA 3LM1A 4PITA 1M26A
chains in the Genus database with same CATH topology
1ZGRA 4R6PA 1TOQA 1ZGSA 3P8SA 2GTYA 5AV7A 3APAA 3LKYA 1UGYC 3VY7A 1X1VA 4R6QA 5J50A 2BMYA 3LL1A 5J4XA 4MQ0A 3LL0A 1TP8A 1UGYA 1UGXA 4AK4A 1OUWA 4WOGA 3WOCA 1UH0A 3LLYA 4PIUA 1J4SA 3O44A 1JOTA 1VBOA 2GUXA 3VZEA 4PIKA 1C3MA 1UH1A 1KUJA 3AQGA 1JACA 1WS5C 2NUOA 3VY6A 4DDNA 2JZ4A 5BN6E 3MITA 4AKBA 1WS5A 3R51A 3VZGA 3WOBA 5JM1A 1XXQA 2HYQA 2BMZA 5EXGA 4AKDA 1C3NA 1UGWC 1WS4C 1VBPA 4R6NA 4PIFA 2BN0A 1J4UA 4GX7A 1UGWA 1WS4A 5J51A 1C3KA 1XXRA 1XEZA 4R6OA 3R52A 1PXDA 3VZFA 5J4TA 1J4TA 2HYRA 2GUDA 3LLZA 3MIVA 4R6RA 4AKCA 2GUEA 1KU8A 3R50A 3LL2A 3MIUA 2NU5A 2GUCA 3LM1A 4PITA 1M26A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZGR A;  4R6P A;  1TOQ A;  1ZGS A;  3P8S A;  2GTY A;  5AV7 A;  3APA A;  3LKY A;  1UGY C;  3VY7 A;  1X1V A;  4R6Q A;  5J50 A;  2BMY A;  3LL1 A;  5J4X A;  4MQ0 A;  3LL0 A;  1TP8 A;  1UGY A;  1UGX A;  4AK4 A;  1OUW A;  4WOG A;  3WOC A;  1UH0 A;  3LLY A;  4PIU A;  1J4S A;  3O44 A;  1JOT A;  1VBO A;  2GUX A;  3VZE A;  4PIK A;  1C3M A;  1UH1 A;  1KUJ A;  3AQG A;  1JAC A;  1WS5 C;  2NUO A;  3VY6 A;  4DDN A;  2JZ4 A;  5BN6 E;  3MIT A;  4AKB A;  1WS5 A;  3R51 A;  3VZG A;  3WOB A;  5JM1 A;  1XXQ A;  2HYQ A;  2BMZ A;  5EXG A;  4AKD A;  1C3N A;  1UGW C;  1WS4 C;  1VBP A;  4R6N A;  4PIF A;  2BN0 A;  1J4U A;  4GX7 A;  1UGW A;  1WS4 A;  5J51 A;  1C3K A;  1XXR A;  1XEZ A;  4R6O A;  3R52 A;  1PXD A;  3VZF A;  5J4T A;  1J4T A;  2HYR A;  2GUD A;  3LLZ A;  3MIV A;  4R6R A;  4AKC A;  2GUE A;  1KU8 A;  3R50 A;  3LL2 A;  3MIU A;  2NU5 A;  2GUC A;  3LM1 A;  4PIT A;  1M26 A; 
#chains in the Genus database with same CATH topology
 1ZGR A;  3EB7 A;  4R6P A;  1TOQ A;  1ZGS A;  3P8S A;  2GTY A;  5AV7 A;  3APA A;  3LKY A;  1UGY C;  3VY7 A;  1X1V A;  4R6Q A;  5J50 A;  2BMY A;  3LL1 A;  5J4X A;  4MQ0 A;  3LL0 A;  1TP8 A;  1UGY A;  1UGX A;  4AK4 A;  1OUW A;  4WOG A;  3WOC A;  1UH0 A;  4W8J A;  3LLY A;  4PIU A;  1J4S A;  3O44 A;  1JOT A;  1VBO A;  2GUX A;  3VZE A;  4PIK A;  1C3M A;  1KUJ A;  1UH1 A;  3AQG A;  1I5P A;  1JAC A;  1WS5 C;  2NUO A;  4QX2 A;  3VY6 A;  4DDN A;  2JZ4 A;  5BN6 E;  3MIT A;  4AKB A;  1WS5 A;  4QX0 A;  4MOA A;  3R51 A;  3VZG A;  3WOB A;  5JM1 A;  1XXQ A;  2HYQ A;  2BMZ A;  4D8M A;  5EXG A;  3TOW A;  4AKD A;  2C9K A;  1C3N A;  4QX1 A;  1UGW C;  1WS4 C;  1VBP A;  4R6N A;  4PIF A;  2BN0 A;  1J4U A;  4GX7 A;  1UGW A;  1WS4 A;  5J51 A;  1CIY A;  4ARX A;  1C3K A;  2QP2 A;  1XXR A;  1XEZ A;  1DLC A;  4QX3 A;  4R6O A;  3R52 A;  1PXD A;  3VZF A;  5J4T A;  1J4T A;  2HYR A;  2GUD A;  3LLZ A;  3MIV A;  4R6R A;  4AKC A;  2GUE A;  1JI6 A;  1KU8 A;  3R50 A;  3LL2 A;  3MIU A;  1VMO A;  1W99 A;  2NU5 A;  4ARY A;  2GUC A;  3LM1 A;  4PIT A;  1M26 A; 
#chains in the Genus database with same CATH homology
 1ZGR A;  4R6P A;  1TOQ A;  1ZGS A;  3P8S A;  2GTY A;  5AV7 A;  3APA A;  3LKY A;  1UGY C;  3VY7 A;  1X1V A;  4R6Q A;  5J50 A;  2BMY A;  3LL1 A;  5J4X A;  4MQ0 A;  3LL0 A;  1TP8 A;  1UGY A;  1UGX A;  4AK4 A;  1OUW A;  4WOG A;  3WOC A;  1UH0 A;  3LLY A;  4PIU A;  1J4S A;  3O44 A;  1JOT A;  1VBO A;  2GUX A;  3VZE A;  4PIK A;  1C3M A;  1UH1 A;  1KUJ A;  3AQG A;  1JAC A;  1WS5 C;  2NUO A;  3VY6 A;  4DDN A;  2JZ4 A;  5BN6 E;  3MIT A;  4AKB A;  1WS5 A;  3R51 A;  3VZG A;  3WOB A;  5JM1 A;  1XXQ A;  2HYQ A;  2BMZ A;  5EXG A;  4AKD A;  1C3N A;  1UGW C;  1WS4 C;  1VBP A;  4R6N A;  4PIF A;  2BN0 A;  1J4U A;  4GX7 A;  1UGW A;  1WS4 A;  5J51 A;  1C3K A;  1XXR A;  1XEZ A;  4R6O A;  3R52 A;  1PXD A;  3VZF A;  5J4T A;  1J4T A;  2HYR A;  2GUD A;  3LLZ A;  3MIV A;  4R6R A;  4AKC A;  2GUE A;  1KU8 A;  3R50 A;  3LL2 A;  3MIU A;  2NU5 A;  2GUC A;  3LM1 A;  4PIT A;  1M26 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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