3LL1A

Monomeric griffithsin with a single gly-ser insertion and mutations to remove residual self-association
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
122
structure length
122
Chain Sequence
SSTHRKFGGSGGSPFSGSGLSSIAVRSGSYLDAIIIDGVHHGGSGGNLSPTFTFGSGEYISNMTIRSGDYIDNISFETNMGRRFGPYGGSGGSANTLSNVKVIQINGSAGDYLDSLDIYYDN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Griffithsia
molecule keywords Griffithsin
total genus 23
structure length 122
sequence length 122
ec nomenclature
pdb deposition date 2010-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01419 Jacalin Jacalin-like lectin domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.100.10.30 Mainly Beta Aligned Prism Vitelline Membrane Outer Layer Protein I, subunit A Jacalin-like lectin domain 3ll1A00
1WS5A 1UGXA 1WS5C 3R51A 1XEZA 3MIVA 3WOBA 2NU5A 3AQGA 1XXQA 4GX7A 3P8SA 1JACA 1J4TA 4AK4A 1X1VA 3VY7A 3WOCA 4AKDA 5J51A 4PIFA 1VBPA 2GTYA 1TP8A 3VZEA 5J50A 2JZ4A 3LLYA 2HYRA 2GUEA 1PXDA 1C3NA 2BN0A 2BMZA 3APAA 5AV7A 4AKCA 4PITA 5EXGA 1ZGRA 1UH1A 2BMYA 1TOQA 1VBOA 3O44A 3VZGA 4R6OA 4PIKA 1KU8A 3VY6A 4R6PA 2GUXA 3LL0A 2HYQA 2GUDA 4R6RA 3LKYA 1UGWA 1UGWC 1ZGSA 4AKBA 3MIUA 1JOTA 4PIUA 1UGYA 1WS4A 3LL1A 1WS4C 5J4XA 5JM1A 1C3MA 3LLZA 1UH0A 1J4UA 1J4SA 5BN6E 3LM1A 3LL2A 4R6QA 3R52A 4R6NA 1C3KA 3R50A 2GUCA 3VZFA 2NUOA 1XXRA 4MQ0A 1KUJA 4WOGA 4DDNA 1OUWA 5J4TA 1M26A 3MITA 1UGYC
chains in the Genus database with same CATH superfamily
4QX1A 1WS5A 1UGXA 4QX2A 1WS5C 3R51A 1XEZA 4D8MA 3MIVA 2QP2A 3WOBA 2NU5A 3AQGA 1XXQA 4GX7A 3P8SA 1JACA 1J4TA 4AK4A 1X1VA 1DLCA 4QX3A 3VY7A 3WOCA 4AKDA 1CIYA 5J51A 4PIFA 1VBPA 2GTYA 1TP8A 3VZEA 5J50A 2JZ4A 4ARYA 3LLYA 2HYRA 2GUEA 4MOAA 1PXDA 1C3NA 2BN0A 2BMZA 1W99A 3APAA 5AV7A 4AKCA 4W8JA 4PITA 5EXGA 1ZGRA 1UH1A 2BMYA 1TOQA 1VBOA 3O44A 3EB7A 3VZGA 4R6OA 4PIKA 1KU8A 1VMOA 3VY6A 4R6PA 2GUXA 3LL0A 2HYQA 4QX0A 2GUDA 3TOWA 1JI6A 4R6RA 3LKYA 1UGWA 1UGWC 1ZGSA 4AKBA 3MIUA 1JOTA 4PIUA 1UGYA 1WS4A 3LL1A 1WS4C 5J4XA 5JM1A 1C3MA 3LLZA 1UH0A 1J4UA 1J4SA 5BN6E 3LM1A 3LL2A 4R6QA 3R52A 4R6NA 4ARXA 1C3KA 3R50A 2GUCA 3VZFA 2NUOA 1XXRA 4MQ0A 1KUJA 4WOGA 4DDNA 1OUWA 5J4TA 1I5PA 2C9KA 1M26A 3MITA 1UGYC
chains in the Genus database with same CATH topology
1WS5A 1UGXA 1WS5C 3R51A 1XEZA 3MIVA 3WOBA 2NU5A 3AQGA 1XXQA 4GX7A 3P8SA 1JACA 1J4TA 4AK4A 1X1VA 3VY7A 3WOCA 4AKDA 5J51A 4PIFA 1VBPA 2GTYA 1TP8A 3VZEA 5J50A 2JZ4A 3LLYA 2HYRA 2GUEA 1PXDA 1C3NA 2BN0A 2BMZA 3APAA 5AV7A 4AKCA 4PITA 5EXGA 1ZGRA 1UH1A 2BMYA 1TOQA 1VBOA 3O44A 3VZGA 4R6OA 4PIKA 1KU8A 3VY6A 4R6PA 2GUXA 3LL0A 2HYQA 2GUDA 4R6RA 3LKYA 1UGWA 1UGWC 1ZGSA 4AKBA 3MIUA 1JOTA 4PIUA 1UGYA 1WS4A 3LL1A 1WS4C 5J4XA 5JM1A 1C3MA 3LLZA 1UH0A 1J4UA 1J4SA 5BN6E 3LM1A 3LL2A 4R6QA 3R52A 4R6NA 1C3KA 3R50A 2GUCA 3VZFA 2NUOA 1XXRA 4MQ0A 1KUJA 4WOGA 4DDNA 1OUWA 5J4TA 1M26A 3MITA 1UGYC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WS5 A;  1UGX A;  1WS5 C;  3R51 A;  1XEZ A;  3MIV A;  3WOB A;  2NU5 A;  3AQG A;  1XXQ A;  4GX7 A;  3P8S A;  1JAC A;  1J4T A;  4AK4 A;  1X1V A;  3VY7 A;  3WOC A;  4AKD A;  5J51 A;  4PIF A;  1VBP A;  2GTY A;  1TP8 A;  3VZE A;  5J50 A;  2JZ4 A;  3LLY A;  2HYR A;  2GUE A;  1PXD A;  1C3N A;  2BN0 A;  2BMZ A;  3APA A;  5AV7 A;  4AKC A;  4PIT A;  5EXG A;  1ZGR A;  1UH1 A;  2BMY A;  1TOQ A;  1VBO A;  3O44 A;  3VZG A;  4R6O A;  4PIK A;  1KU8 A;  3VY6 A;  4R6P A;  2GUX A;  3LL0 A;  2HYQ A;  2GUD A;  4R6R A;  3LKY A;  1UGW A;  1UGW C;  1ZGS A;  4AKB A;  3MIU A;  1JOT A;  4PIU A;  1UGY A;  1WS4 A;  3LL1 A;  1WS4 C;  5J4X A;  5JM1 A;  1C3M A;  3LLZ A;  1UH0 A;  1J4U A;  1J4S A;  5BN6 E;  3LM1 A;  3LL2 A;  4R6Q A;  3R52 A;  4R6N A;  1C3K A;  3R50 A;  2GUC A;  3VZF A;  2NUO A;  1XXR A;  4MQ0 A;  1KUJ A;  4WOG A;  4DDN A;  1OUW A;  5J4T A;  1M26 A;  3MIT A;  1UGY C; 
#chains in the Genus database with same CATH topology
 4QX1 A;  1WS5 A;  1UGX A;  4QX2 A;  1WS5 C;  3R51 A;  1XEZ A;  4D8M A;  3MIV A;  2QP2 A;  3WOB A;  2NU5 A;  3AQG A;  1XXQ A;  4GX7 A;  3P8S A;  1JAC A;  1J4T A;  4AK4 A;  1X1V A;  1DLC A;  4QX3 A;  3VY7 A;  3WOC A;  4AKD A;  1CIY A;  5J51 A;  4PIF A;  1VBP A;  2GTY A;  1TP8 A;  3VZE A;  5J50 A;  2JZ4 A;  4ARY A;  3LLY A;  2HYR A;  2GUE A;  4MOA A;  1PXD A;  1C3N A;  2BN0 A;  2BMZ A;  1W99 A;  3APA A;  5AV7 A;  4AKC A;  4W8J A;  4PIT A;  5EXG A;  1ZGR A;  1UH1 A;  2BMY A;  1TOQ A;  1VBO A;  3O44 A;  3EB7 A;  3VZG A;  4R6O A;  4PIK A;  1KU8 A;  1VMO A;  3VY6 A;  4R6P A;  2GUX A;  3LL0 A;  2HYQ A;  4QX0 A;  2GUD A;  3TOW A;  1JI6 A;  4R6R A;  3LKY A;  1UGW A;  1UGW C;  1ZGS A;  4AKB A;  3MIU A;  1JOT A;  4PIU A;  1UGY A;  1WS4 A;  3LL1 A;  1WS4 C;  5J4X A;  5JM1 A;  1C3M A;  3LLZ A;  1UH0 A;  1J4U A;  1J4S A;  5BN6 E;  3LM1 A;  3LL2 A;  4R6Q A;  3R52 A;  4R6N A;  4ARX A;  1C3K A;  3R50 A;  2GUC A;  3VZF A;  2NUO A;  1XXR A;  4MQ0 A;  1KUJ A;  4WOG A;  4DDN A;  1OUW A;  5J4T A;  1I5P A;  2C9K A;  1M26 A;  3MIT A;  1UGY C; 
#chains in the Genus database with same CATH homology
 1WS5 A;  1UGX A;  1WS5 C;  3R51 A;  1XEZ A;  3MIV A;  3WOB A;  2NU5 A;  3AQG A;  1XXQ A;  4GX7 A;  3P8S A;  1JAC A;  1J4T A;  4AK4 A;  1X1V A;  3VY7 A;  3WOC A;  4AKD A;  5J51 A;  4PIF A;  1VBP A;  2GTY A;  1TP8 A;  3VZE A;  5J50 A;  2JZ4 A;  3LLY A;  2HYR A;  2GUE A;  1PXD A;  1C3N A;  2BN0 A;  2BMZ A;  3APA A;  5AV7 A;  4AKC A;  4PIT A;  5EXG A;  1ZGR A;  1UH1 A;  2BMY A;  1TOQ A;  1VBO A;  3O44 A;  3VZG A;  4R6O A;  4PIK A;  1KU8 A;  3VY6 A;  4R6P A;  2GUX A;  3LL0 A;  2HYQ A;  2GUD A;  4R6R A;  3LKY A;  1UGW A;  1UGW C;  1ZGS A;  4AKB A;  3MIU A;  1JOT A;  4PIU A;  1UGY A;  1WS4 A;  3LL1 A;  1WS4 C;  5J4X A;  5JM1 A;  1C3M A;  3LLZ A;  1UH0 A;  1J4U A;  1J4S A;  5BN6 E;  3LM1 A;  3LL2 A;  4R6Q A;  3R52 A;  4R6N A;  1C3K A;  3R50 A;  2GUC A;  3VZF A;  2NUO A;  1XXR A;  4MQ0 A;  1KUJ A;  4WOG A;  4DDN A;  1OUW A;  5J4T A;  1M26 A;  3MIT A;  1UGY C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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