3LPQA

Human mitoneet with 2fe-2s coordinating ligand his 87 replaced with cys
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
75
structure length
75
Chain Sequence
RFYVKDHRNKAMINLHIQKDNPKIVHAFDMEDLGDKAVYCRCWRSKKFPFCDGACTKHNEETGDNVGPLIIKKKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutation of the His ligand in mitoNEET stabilizes the 2Fe-2S cluster despite conformational heterogeneity in the ligand environment.
pubmed doi rcsb
molecule keywords CDGSH iron sulfur domain-containing protein 1
molecule tags Metal binding protein
source organism Homo sapiens
total genus 12
structure length 75
sequence length 75
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09360 zf-CDGSH Iron-binding zinc finger CDGSH type
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.5.90 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L9; domain 1 Ribosomal Protein L9; domain 1 3lpqA00
3TBNA 3S2RA 2QH7A 3EW0A 3TBOA 4EZFA 3FNVA 3LPQA 4F28A 4F1EA 3S2QA 4OO7A 2QD0A 4F2CA 4OOAA 3REEA 2R13A
chains in the Genus database with same CATH superfamily
2QH7A 5GHRB 3S2QA 4KW7A 4OOAA 4OO7A 3REEA 2E9XB 2Q9QB 2HBBA 4EZFA 3FNVA 4F28A 2Q9QA 1DIVA 3FNDA 2QD0A 3TBOA 2R13A 3ANWA 3TBNA 4RSRA 3S2RA 3J7ZH 3EW0A 5EG5A 2OUTA 3LPQA 2E9XD 2HJQA 2EHOC 2LSMA 3CO4A 4F2CA 1CQUA 4FSDA 2X49A 4FS8A 2HBAA 4F1EA 4UY8H 2X4AA 4FR0A 5GHSC 2HVFA
chains in the Genus database with same CATH topology
2QH7A 5GHRB 3S2QA 4KW7A 4OOAA 4OO7A 3REEA 2E9XB 2Q9QB 4EZFA 3FNVA 4F28A 2Q9QA 2QD0A 3TBOA 2R13A 3ANWA 3TBNA 4RSRA 3S2RA 3EW0A 5EG5A 2OUTA 3LPQA 2E9XD 2EHOC 2LSMA 4F2CA 4FSDA 2X49A 4FS8A 4F1EA 2X4AA 4FR0A 5GHSC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TBN A;  3S2R A;  2QH7 A;  3EW0 A;  3TBO A;  4EZF A;  3FNV A;  3LPQ A;  4F28 A;  4F1E A;  3S2Q A;  4OO7 A;  2QD0 A;  4F2C A;  4OOA A;  3REE A;  2R13 A; 
#chains in the Genus database with same CATH topology
 2QH7 A;  5GHR B;  3S2Q A;  4KW7 A;  4OOA A;  4OO7 A;  3REE A;  2E9X B;  2Q9Q B;  2HBB A;  4EZF A;  3FNV A;  4F28 A;  2Q9Q A;  1DIV A;  3FND A;  2QD0 A;  3TBO A;  2R13 A;  3ANW A;  3TBN A;  4RSR A;  3S2R A;  3J7Z H;  3EW0 A;  5EG5 A;  2OUT A;  3LPQ A;  2E9X D;  2HJQ A;  2EHO C;  2LSM A;  3CO4 A;  4F2C A;  1CQU A;  4FSD A;  2X49 A;  4FS8 A;  2HBA A;  4F1E A;  4UY8 H;  2X4A A;  4FR0 A;  5GHS C;  2HVF A; 
#chains in the Genus database with same CATH homology
 2QH7 A;  5GHR B;  3S2Q A;  4KW7 A;  4OOA A;  4OO7 A;  3REE A;  2E9X B;  2Q9Q B;  4EZF A;  3FNV A;  4F28 A;  2Q9Q A;  2QD0 A;  3TBO A;  2R13 A;  3ANW A;  3TBN A;  4RSR A;  3S2R A;  3EW0 A;  5EG5 A;  2OUT A;  3LPQ A;  2E9X D;  2EHO C;  2LSM A;  4F2C A;  4FSD A;  2X49 A;  4FS8 A;  4F1E A;  2X4A A;  4FR0 A;  5GHS C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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