3LPQA

Human mitoneet with 2fe-2s coordinating ligand his 87 replaced with cys
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
75
structure length
75
Chain Sequence
RFYVKDHRNKAMINLHIQKDNPKIVHAFDMEDLGDKAVYCRCWRSKKFPFCDGACTKHNEETGDNVGPLIIKKKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutation of the His ligand in mitoNEET stabilizes the 2Fe-2S cluster despite conformational heterogeneity in the ligand environment.
pubmed doi rcsb
molecule keywords CDGSH iron sulfur domain-containing protein 1
molecule tags Metal binding protein
source organism Homo sapiens
total genus 12
structure length 75
sequence length 75
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09360 zf-CDGSH Iron-binding zinc finger CDGSH type
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.5.90 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L9; domain 1 Ribosomal Protein L9; domain 1 3lpqA00
3LPQA 2QH7A 3FNVA 2QD0A 2R13A 4F28A 3TBNA 4OO7A 3EW0A 3S2QA 3TBOA 4F1EA 4F2CA 4OOAA 3REEA 4EZFA 3S2RA
chains in the Genus database with same CATH superfamily
3LPQA 2X49A 2QH7A 3FNVA 2E9XB 2QD0A 2R13A 2HBAA 4F28A 3TBOA 3ANWA 4F2CA 2Q9QA 2HBBA 2HVFA 2E9XD 4FR0A 3FNDA 4FSDA 1DIVA 3S2QA 5GHSC 2LSMA 2Q9QB 4F1EA 3REEA 5GHRB 2X4AA 3TBNA 4UY8H 1CQUA 3EW0A 3J7ZH 2HJQA 2EHOC 4FS8A 5EG5A 4KW7A 4OO7A 3CO4A 2OUTA 4OOAA 4RSRA 4EZFA 3S2RA
chains in the Genus database with same CATH topology
3LPQA 2X49A 2QH7A 3FNVA 2E9XB 2QD0A 2R13A 4F28A 3TBOA 3ANWA 4F2CA 2Q9QA 4FR0A 2E9XD 4FSDA 3S2QA 5GHSC 2LSMA 2Q9QB 4F1EA 3REEA 5GHRB 2X4AA 3TBNA 3EW0A 2EHOC 4FS8A 5EG5A 4KW7A 4OO7A 2OUTA 4OOAA 4RSRA 4EZFA 3S2RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LPQ A;  2QH7 A;  3FNV A;  2QD0 A;  2R13 A;  4F28 A;  3TBN A;  4OO7 A;  3EW0 A;  3S2Q A;  3TBO A;  4F1E A;  4F2C A;  4OOA A;  3REE A;  4EZF A;  3S2R A; 
#chains in the Genus database with same CATH topology
 3LPQ A;  2X49 A;  2QH7 A;  3FNV A;  2E9X B;  2QD0 A;  2R13 A;  2HBA A;  4F28 A;  3TBO A;  3ANW A;  4F2C A;  2Q9Q A;  2HBB A;  2HVF A;  2E9X D;  4FR0 A;  3FND A;  4FSD A;  1DIV A;  3S2Q A;  5GHS C;  2LSM A;  2Q9Q B;  4F1E A;  3REE A;  5GHR B;  2X4A A;  3TBN A;  4UY8 H;  1CQU A;  3EW0 A;  3J7Z H;  2HJQ A;  2EHO C;  4FS8 A;  5EG5 A;  4KW7 A;  4OO7 A;  3CO4 A;  2OUT A;  4OOA A;  4RSR A;  4EZF A;  3S2R A; 
#chains in the Genus database with same CATH homology
 3LPQ A;  2X49 A;  2QH7 A;  3FNV A;  2E9X B;  2QD0 A;  2R13 A;  4F28 A;  3TBO A;  3ANW A;  4F2C A;  2Q9Q A;  4FR0 A;  2E9X D;  4FSD A;  3S2Q A;  5GHS C;  2LSM A;  2Q9Q B;  4F1E A;  3REE A;  5GHR B;  2X4A A;  3TBN A;  3EW0 A;  2EHO C;  4FS8 A;  5EG5 A;  4KW7 A;  4OO7 A;  2OUT A;  4OOA A;  4RSR A;  4EZF A;  3S2R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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