3N7R | Genus

Total Genus 24

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	24
sequence length	97
structure length	91
Chain Sequence	IQLGVTRNKIMTAQYECYQKIMQDPVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCN

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 91 atoms

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91 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Crystal Structure of the Ectodomain Complex of the CGRP Receptor, a Class-B GPCR, Reveals the Site of Drug Antagonism. pubmed doi rcsb
molecule keywords	Calcitonin gene-related peptide type 1 receptor
molecule tags	Membrane protein
source organism	Homo sapiens
total genus	24
structure length	91
sequence length	97
chains with identical sequence	B
ec nomenclature
pdb deposition date	2010-05-27

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02793	HRM	Hormone receptor domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
4.10.1240.10	Few Secondary Structures	Irregular	Hormone receptor fold	GPCR, family 2, extracellular hormone receptor domain	3n7rA00

3N7SA 3C5TA 3H3GA 2JNCA 3L2JA 2QKHA 2L27A 3C59A 3EHTA 4HJ0A 3N7PA 4ZGMA 4LF3C 5II0A 3AQFB 3IOLA 4ERSA 4DLQA 4DLOA 2JODA 1U34A 3C4MA 2JNDA 3EHUA 3EHSA 3N7RA 2XDGA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3N7S A;  3C5T A;  3H3G A;  2JNC A;  3L2J A;  2QKH A;  2L27 A;  3C59 A;  3EHT A;  4HJ0 A;  3N7P A;  4ZGM A;  4LF3 C;  5II0 A;  3AQF B;  3IOL A;  4ERS A;  4DLQ A;  4DLO A;  2JOD A;  1U34 A;  3C4M A;  2JND A;  3EHU A;  3EHS A;  3N7R A;  2XDG A; 
#chains in the Genus database with same CATH topology
 3N7S A;  3C5T A;  3H3G A;  2JNC A;  3L2J A;  2QKH A;  2L27 A;  3C59 A;  3EHT A;  4HJ0 A;  3N7P A;  4ZGM A;  4LF3 C;  5II0 A;  3AQF B;  3IOL A;  4ERS A;  4DLQ A;  4DLO A;  2JOD A;  1U34 A;  3C4M A;  2JND A;  3EHU A;  3EHS A;  3N7R A;  2XDG A; 
#chains in the Genus database with same CATH homology
 3N7S A;  3C5T A;  3H3G A;  2JNC A;  3L2J A;  2QKH A;  2L27 A;  3C59 A;  3EHT A;  4HJ0 A;  3N7P A;  4ZGM A;  4LF3 C;  5II0 A;  3AQF B;  3IOL A;  4ERS A;  4DLQ A;  4DLO A;  2JOD A;  1U34 A;  3C4M A;  2JND A;  3EHU A;  3EHS A;  3N7R A;  2XDG A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3N7RA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations