3PVUG

Bovine grk2 in complex with gbetagamma subunits and a selective kinase inhibitor (cmpd101)
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
60
structure length
60
Chain Sequence
SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors.
pubmed doi rcsb
molecule tags Transferase/signaling protein/inhibitor
source organism Bos taurus
molecule keywords Beta-adrenergic receptor kinase 1
total genus 13
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 2010-12-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 3pvuG00
2TRCG 3AH8G 1OMWG 1XHMB 5TDHG 5KDOG 1B9YB 1GG2G 3PSCG 2PBIA 1TBGE 1GOTG 2BCJG 5HE0G 1B9XB 3SN6G 5HE3G 3KRWG 1GP2G 1A0RG 3PVWG 4KFMG 3PVUG 3V5WG 5HE1G 5HE2G 4PNKG 3KRXG 4MK0G 3CIKG
chains in the Genus database with same CATH superfamily
1IOJA 2TRCG 3AH8G 1OMWG 1XHMB 5TDHG 5KDOG 1B9YB 3PSCG 1GG2G 1HFES 2PBIA 1TBGE 1GOTG 2BCJG 5HE0G 1B9XB 3SN6G 5HE3G 3KRWG 1GP2G 1A0RG 3PVWG 4KFMG 3PVUG 3V5WG 5HE1G 5HE2G 4PNKG 3KRXG 4MK0G 3CIKG
chains in the Genus database with same CATH topology
2TRCG 3AH8G 1OMWG 1XHMB 5TDHG 5KDOG 1B9YB 1GG2G 3PSCG 2PBIA 1TBGE 1GOTG 2BCJG 5HE0G 1B9XB 3SN6G 5HE3G 3KRWG 1GP2G 1A0RG 3PVWG 4KFMG 3PVUG 3V5WG 5HE1G 5HE2G 4PNKG 3KRXG 4MK0G 3CIKG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2TRC G;  3AH8 G;  1OMW G;  1XHM B;  5TDH G;  5KDO G;  1B9Y B;  1GG2 G;  3PSC G;  2PBI A;  1TBG E;  1GOT G;  2BCJ G;  5HE0 G;  1B9X B;  3SN6 G;  5HE3 G;  3KRW G;  1GP2 G;  1A0R G;  3PVW G;  4KFM G;  3PVU G;  3V5W G;  5HE1 G;  5HE2 G;  4PNK G;  3KRX G;  4MK0 G;  3CIK G; 
#chains in the Genus database with same CATH topology
 1IOJ A;  2TRC G;  3AH8 G;  1OMW G;  1XHM B;  5TDH G;  5KDO G;  1B9Y B;  3PSC G;  1GG2 G;  1HFE S;  2PBI A;  1TBG E;  1GOT G;  2BCJ G;  5HE0 G;  1B9X B;  3SN6 G;  5HE3 G;  3KRW G;  1GP2 G;  1A0R G;  3PVW G;  4KFM G;  3PVU G;  3V5W G;  5HE1 G;  5HE2 G;  4PNK G;  3KRX G;  4MK0 G;  3CIK G; 
#chains in the Genus database with same CATH homology
 2TRC G;  3AH8 G;  1OMW G;  1XHM B;  5TDH G;  5KDO G;  1B9Y B;  1GG2 G;  3PSC G;  2PBI A;  1TBG E;  1GOT G;  2BCJ G;  5HE0 G;  1B9X B;  3SN6 G;  5HE3 G;  3KRW G;  1GP2 G;  1A0R G;  3PVW G;  4KFM G;  3PVU G;  3V5W G;  5HE1 G;  5HE2 G;  4PNK G;  3KRX G;  4MK0 G;  3CIK G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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