3PVU | Genus

Total Genus 13

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	13
sequence length	60
structure length	60
Chain Sequence	SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFF

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 60 atoms

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60 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors. pubmed doi rcsb
molecule keywords	Beta-adrenergic receptor kinase 1
molecule tags	Transferase/signaling protein/inhibitor
source organism	Bos taurus
total genus	13
structure length	60
sequence length	60
ec nomenclature
pdb deposition date	2010-12-07

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
4.10.260.10	Few Secondary Structures	Irregular	G Protein Gi Gamma 2	Transducin (heterotrimeric G protein), gamma chain	3pvuG00

3SN6G 5HE1G 3PVUG 3KRWG 2PBIA 5HE2G 5HE0G 4PNKG 2BCJG 2TRCG 1B9XB 1GOTG 1A0RG 3PVWG 1GG2G 3V5WG 1XHMB 4MK0G 3CIKG 1TBGE 1OMWG 5TDHG 1GP2G 3KRXG 5HE3G 5KDOG 4KFMG 1B9YB 3AH8G 3PSCG
chains in the Genus database with same CATH superfamily

3SN6G 5HE1G 3PVUG 1HFES 3KRWG 2PBIA 5HE2G 5HE0G 4PNKG 2BCJG 2TRCG 1B9XB 1GOTG 1A0RG 3PVWG 1GG2G 3V5WG 1XHMB 4MK0G 3CIKG 1IOJA 1TBGE 1OMWG 5TDHG 1GP2G 3KRXG 5HE3G 5KDOG 4KFMG 1B9YB 3AH8G 3PSCG
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3SN6 G;  5HE1 G;  3PVU G;  3KRW G;  2PBI A;  5HE2 G;  5HE0 G;  4PNK G;  2BCJ G;  2TRC G;  1B9X B;  1GOT G;  1A0R G;  3PVW G;  1GG2 G;  3V5W G;  1XHM B;  4MK0 G;  3CIK G;  1TBG E;  1OMW G;  5TDH G;  1GP2 G;  3KRX G;  5HE3 G;  5KDO G;  4KFM G;  1B9Y B;  3AH8 G;  3PSC G; 
#chains in the Genus database with same CATH topology
 3SN6 G;  5HE1 G;  3PVU G;  1HFE S;  3KRW G;  2PBI A;  5HE2 G;  5HE0 G;  4PNK G;  2BCJ G;  2TRC G;  1B9X B;  1GOT G;  1A0R G;  3PVW G;  1GG2 G;  3V5W G;  1XHM B;  4MK0 G;  3CIK G;  1IOJ A;  1TBG E;  1OMW G;  5TDH G;  1GP2 G;  3KRX G;  5HE3 G;  5KDO G;  4KFM G;  1B9Y B;  3AH8 G;  3PSC G; 
#chains in the Genus database with same CATH homology
 3SN6 G;  5HE1 G;  3PVU G;  3KRW G;  2PBI A;  5HE2 G;  5HE0 G;  4PNK G;  2BCJ G;  2TRC G;  1B9X B;  1GOT G;  1A0R G;  3PVW G;  1GG2 G;  3V5W G;  1XHM B;  4MK0 G;  3CIK G;  1TBG E;  1OMW G;  5TDH G;  1GP2 G;  3KRX G;  5HE3 G;  5KDO G;  4KFM G;  1B9Y B;  3AH8 G;  3PSC G;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3PVUG

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN