3T5GB

Structure of fully modified farnesylated rheb in complex with pde6d
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
147
structure length
147
Chain Sequence
KDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSRVRLFYV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo.
pubmed doi rcsb
molecule tags Signaling protein,lipid binding protein
source organism Homo sapiens
molecule keywords GTP-binding protein Rheb
total genus 40
structure length 147
sequence length 147
ec nomenclature
pdb deposition date 2011-07-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF05351 GMP_PDE_delta GMP-PDE, delta subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.50.40 Mainly Beta Distorted Sandwich Coagulation Factor XIII; Chain A, domain 1 GMP phosphodiesterase, delta subunit 3t5gB00
1KSGB 3T5IA 4JV6B 3RBQA 5F2UA 1KSJB 4GOJC 1KSHB 5TB5B 4JV8B 4JVBB 4JHPB 5E8FA 3T5GB 5TARB 5L7KA 4JVFB 4GOKC 3GQQA 5E80A
chains in the Genus database with same CATH superfamily
4RE1A 4ALEA 3KYSA 1FSTA 4B5QA 4ALTA 5FTZA 1KSHB 4OY6A 4JVBB 1FT3A 5E8FA 5DQ8A 2YOXA 5HGUA 5HNOA 5L7KA 4ALSA 4EISA 2YOYA 4GOKC 5HNPA 4QI8A 2VTCA 5E80A 4A02A 4D7VA 3T5IA 4JV6B 2JHVA 5DQEA 5IJUA 5ACFA 4MAIA 4OY8A 3RBQA 4ALRA 4GOJC 1GDFA 1QVYA 2BENA 5FJQA 4F38B 5EMVA 2BEMA 2JHWA 2XWXA 4OY7A 3T5GB 2R5OA 2JHXA 2YOWA 2JI0A 3EJAA 1FSOA 1AJWA 4MAHA 5ACGA 1KSGB 4D7UA 1FT0A 5ACJA 1KMTA 1KSJB 2LHSA 4GBOA 3UAMA 5TB5B 1DOAB 2JHUA 4JHPB 1DS6B 2YETA 4LN0A 1HH4D 4FMRA 3EIIA 3JUAA 5TARB 4ALQA 5AA7A 2BXWA 4JVFB 4ALCA 2JHZA 1RHOA 4EIRA 5F2UA 2JHTA 3L15A 4JV8B 5ACHA 4EISB 5EMWA 2JHYA 5ACIA 5FOHA 2JHSA 3GQQA 3ZUDA
chains in the Genus database with same CATH topology
1KSGB 3T5IA 4JV6B 3RBQA 5F2UA 1KSJB 4GOJC 1KSHB 5TB5B 4JV8B 4JVBB 4JHPB 5E8FA 3T5GB 5TARB 5L7KA 4JVFB 4GOKC 3GQQA 5E80A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KSG B;  3T5I A;  4JV6 B;  3RBQ A;  5F2U A;  1KSJ B;  4GOJ C;  1KSH B;  5TB5 B;  4JV8 B;  4JVB B;  4JHP B;  5E8F A;  3T5G B;  5TAR B;  5L7K A;  4JVF B;  4GOK C;  3GQQ A;  5E80 A; 
#chains in the Genus database with same CATH topology
 4RE1 A;  4ALE A;  3KYS A;  1FST A;  4B5Q A;  4ALT A;  5FTZ A;  1KSH B;  4OY6 A;  4JVB B;  1FT3 A;  5E8F A;  5DQ8 A;  2YOX A;  5HGU A;  5HNO A;  5L7K A;  4ALS A;  4EIS A;  2YOY A;  4GOK C;  5HNP A;  4QI8 A;  2VTC A;  5E80 A;  4A02 A;  4D7V A;  3T5I A;  4JV6 B;  2JHV A;  5DQE A;  5IJU A;  5ACF A;  4MAI A;  4OY8 A;  3RBQ A;  4ALR A;  4GOJ C;  1GDF A;  1QVY A;  2BEN A;  5FJQ A;  4F38 B;  5EMV A;  2BEM A;  2JHW A;  2XWX A;  4OY7 A;  3T5G B;  2R5O A;  2JHX A;  2YOW A;  2JI0 A;  3EJA A;  1FSO A;  1AJW A;  4MAH A;  5ACG A;  1KSG B;  4D7U A;  1FT0 A;  5ACJ A;  1KMT A;  1KSJ B;  2LHS A;  4GBO A;  3UAM A;  5TB5 B;  1DOA B;  2JHU A;  4JHP B;  1DS6 B;  2YET A;  4LN0 A;  1HH4 D;  4FMR A;  3EII A;  3JUA A;  5TAR B;  4ALQ A;  5AA7 A;  2BXW A;  4JVF B;  4ALC A;  2JHZ A;  1RHO A;  4EIR A;  5F2U A;  2JHT A;  3L15 A;  4JV8 B;  5ACH A;  4EIS B;  5EMW A;  2JHY A;  5ACI A;  5FOH A;  2JHS A;  3GQQ A;  3ZUD A; 
#chains in the Genus database with same CATH homology
 1KSG B;  3T5I A;  4JV6 B;  3RBQ A;  5F2U A;  1KSJ B;  4GOJ C;  1KSH B;  5TB5 B;  4JV8 B;  4JVB B;  4JHP B;  5E8F A;  3T5G B;  5TAR B;  5L7K A;  4JVF B;  4GOK C;  3GQQ A;  5E80 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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