3TNZA

Crystal structure of mus musculus iodotyrosine deiodinase (iyd) c217a, c239a bound to fmn and mono-iodotyrosine (mit)
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
222
structure length
222
Chain Sequence
SVEHIPFSHTRYPEQEMRMRSQEFYELLNKRRSVRFISSEHVPMEVIENVIKAAGTAPSGAHTEPWTFVVVKDPDMKHKIREIIEEEEEINYMKRMGKRWVTDLKKLRTNWIKEYLDTAPVLILIFKQVHGFAANGKKKVHYYNEISVSIAAGLLLAALQNAGLVTVTTTPLNAGPRLRVLLGRPSHEKLLVLLPVGYPSRDATVPDLKRKALDQIMVTVHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Expression of a soluble form of iodotyrosine deiodinase for active site characterization by engineering the native membrane protein from Mus musculus.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Mus musculus
molecule keywords Iodotyrosine dehalogenase 1
total genus 63
structure length 222
sequence length 222
chains with identical sequence B
ec nomenclature ec 1.21.1.1: Iodotyrosine deiodinase.
pdb deposition date 2011-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00881 Nitroreductase Nitroreductase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.109.10 Alpha Beta 3-Layer(aba) Sandwich NADH Oxidase NADH Oxidase 3tnzA01
3QDLA 3M5KA 3X21A 5HEIA 3GFAA 3GE5A 3E39A 2WZVA 3OF4A 3PXVA 3EOFA 4XOQA 3X22A 4BN8A 1YWQA 5J6CA 3HZNA 4BN6A 1NECA 2H0UA 1V5YA 4TTCA 3BEMA 1KQDA 3BM2A 5KO7A 4BN7A 1F5VA 4BNBA 3TNZA 3H4OA 3HOIA 1OONA 3EO7A 2B67A 5HDJA 3GE6A 3N2SA 5KO8A 1V5ZA 4QLYA 2ISKA 2FREA 3GR3A 4XOMA 4G8SA 1YKIA 3GH8A 2HAYA 4XOOA 2IFAA 3G14A 1IDTA 1KQCA 5KRDA 3GBHA 3GAGA 1ICVA 3BM1A 3K6HA 1OO6A 3GB5A 2WZWA 1YLRA 1BKJA 2ISLA 3KWKA 4BN9A 1ICRA 3E10A 1DS7A 3EK3A 1VFRA 4EO3A 4URPA 4DN2A 3GFDA 1VKWA 1OO5A 4QLXA 1ICUA 1NOXA 2BKJA 2I7HA 3KOQA 2ISJA 3HJ9A 2WQFA 1OOQA 1ZCHA 4TTBA 1YLUA 3EO8A 1KQBA 3TO0A 2R01A 2YMVA
chains in the Genus database with same CATH superfamily
3QDLA 3M5KA 3X21A 5HEIA 3GFAA 3GE5A 3E39A 2WZVA 3OF4A 3PXVA 3EOFA 4XOQA 3X22A 4BN8A 1YWQA 5J6CA 3HZNA 4BN6A 1NECA 2H0UA 1V5YA 4TTCA 3BEMA 1KQDA 3BM2A 5KO7A 4BN7A 1F5VA 4BNBA 3TNZA 3H4OA 3HOIA 1OONA 3EO7A 2B67A 5HDJA 3GE6A 3N2SA 5KO8A 1V5ZA 4QLYA 2ISKA 2FREA 3GR3A 4XOMA 4G8SA 1YKIA 3GH8A 2HAYA 4XOOA 2IFAA 3G14A 1IDTA 1KQCA 5KRDA 3GBHA 3GAGA 1ICVA 3BM1A 3K6HA 1OO6A 3GB5A 2WZWA 1YLRA 1BKJA 2ISLA 3KWKA 4BN9A 1ICRA 3E10A 1DS7A 3EK3A 1VFRA 4EO3A 4URPA 4DN2A 3GFDA 1VKWA 1OO5A 4QLXA 1ICUA 1NOXA 2BKJA 2I7HA 3KOQA 2ISJA 3HJ9A 2WQFA 1OOQA 1J6RA 1ZCHA 4TTBA 1YLUA 3EO8A 1KQBA 3TO0A 2R01A 2YMVA
chains in the Genus database with same CATH topology
3QDLA 3M5KA 3X21A 5HEIA 3GFAA 3GE5A 3E39A 2WZVA 3OF4A 3PXVA 3EOFA 4XOQA 3X22A 4BN8A 1YWQA 5J6CA 3HZNA 4BN6A 1NECA 2H0UA 1V5YA 4TTCA 3BEMA 1KQDA 3BM2A 5KO7A 4BN7A 1F5VA 4BNBA 3TNZA 3H4OA 3HOIA 1OONA 3EO7A 2B67A 5HDJA 3GE6A 3N2SA 5KO8A 1V5ZA 4QLYA 2ISKA 2FREA 3GR3A 4XOMA 4G8SA 1YKIA 3GH8A 2HAYA 4XOOA 2IFAA 3G14A 1IDTA 1KQCA 5KRDA 3GBHA 3GAGA 1ICVA 3BM1A 3K6HA 1OO6A 3GB5A 2WZWA 1YLRA 1BKJA 2ISLA 3KWKA 4BN9A 1ICRA 3E10A 1DS7A 3EK3A 1VFRA 4EO3A 4URPA 4DN2A 3GFDA 1VKWA 1OO5A 4QLXA 1ICUA 1NOXA 2BKJA 2I7HA 3KOQA 2ISJA 3HJ9A 2WQFA 1OOQA 1J6RA 1ZCHA 4TTBA 1YLUA 3EO8A 1KQBA 3TO0A 2R01A 2YMVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QDL A;  3M5K A;  3X21 A;  5HEI A;  3GFA A;  3GE5 A;  3E39 A;  2WZV A;  3OF4 A;  3PXV A;  3EOF A;  4XOQ A;  3X22 A;  4BN8 A;  1YWQ A;  5J6C A;  3HZN A;  4BN6 A;  1NEC A;  2H0U A;  1V5Y A;  4TTC A;  3BEM A;  1KQD A;  3BM2 A;  5KO7 A;  4BN7 A;  1F5V A;  4BNB A;  3TNZ A;  3H4O A;  3HOI A;  1OON A;  3EO7 A;  2B67 A;  5HDJ A;  3GE6 A;  3N2S A;  5KO8 A;  1V5Z A;  4QLY A;  2ISK A;  2FRE A;  3GR3 A;  4XOM A;  4G8S A;  1YKI A;  3GH8 A;  2HAY A;  4XOO A;  2IFA A;  3G14 A;  1IDT A;  1KQC A;  5KRD A;  3GBH A;  3GAG A;  1ICV A;  3BM1 A;  3K6H A;  1OO6 A;  3GB5 A;  2WZW A;  1YLR A;  1BKJ A;  2ISL A;  3KWK A;  4BN9 A;  1ICR A;  3E10 A;  1DS7 A;  3EK3 A;  1VFR A;  4EO3 A;  4URP A;  4DN2 A;  3GFD A;  1VKW A;  1OO5 A;  4QLX A;  1ICU A;  1NOX A;  2BKJ A;  2I7H A;  3KOQ A;  2ISJ A;  3HJ9 A;  2WQF A;  1OOQ A;  1ZCH A;  4TTB A;  1YLU A;  3EO8 A;  1KQB A;  3TO0 A;  2R01 A;  2YMV A; 
#chains in the Genus database with same CATH topology
 3QDL A;  3M5K A;  3X21 A;  5HEI A;  3GFA A;  3GE5 A;  3E39 A;  2WZV A;  3OF4 A;  3PXV A;  3EOF A;  4XOQ A;  3X22 A;  4BN8 A;  1YWQ A;  5J6C A;  3HZN A;  4BN6 A;  1NEC A;  2H0U A;  1V5Y A;  4TTC A;  3BEM A;  1KQD A;  3BM2 A;  5KO7 A;  4BN7 A;  1F5V A;  4BNB A;  3TNZ A;  3H4O A;  3HOI A;  1OON A;  3EO7 A;  2B67 A;  5HDJ A;  3GE6 A;  3N2S A;  5KO8 A;  1V5Z A;  4QLY A;  2ISK A;  2FRE A;  3GR3 A;  4XOM A;  4G8S A;  1YKI A;  3GH8 A;  2HAY A;  4XOO A;  2IFA A;  3G14 A;  1IDT A;  1KQC A;  5KRD A;  3GBH A;  3GAG A;  1ICV A;  3BM1 A;  3K6H A;  1OO6 A;  3GB5 A;  2WZW A;  1YLR A;  1BKJ A;  2ISL A;  3KWK A;  4BN9 A;  1ICR A;  3E10 A;  1DS7 A;  3EK3 A;  1VFR A;  4EO3 A;  4URP A;  4DN2 A;  3GFD A;  1VKW A;  1OO5 A;  4QLX A;  1ICU A;  1NOX A;  2BKJ A;  2I7H A;  3KOQ A;  2ISJ A;  3HJ9 A;  2WQF A;  1OOQ A;  1J6R A;  1ZCH A;  4TTB A;  1YLU A;  3EO8 A;  1KQB A;  3TO0 A;  2R01 A;  2YMV A; 
#chains in the Genus database with same CATH homology
 3QDL A;  3M5K A;  3X21 A;  5HEI A;  3GFA A;  3GE5 A;  3E39 A;  2WZV A;  3OF4 A;  3PXV A;  3EOF A;  4XOQ A;  3X22 A;  4BN8 A;  1YWQ A;  5J6C A;  3HZN A;  4BN6 A;  1NEC A;  2H0U A;  1V5Y A;  4TTC A;  3BEM A;  1KQD A;  3BM2 A;  5KO7 A;  4BN7 A;  1F5V A;  4BNB A;  3TNZ A;  3H4O A;  3HOI A;  1OON A;  3EO7 A;  2B67 A;  5HDJ A;  3GE6 A;  3N2S A;  5KO8 A;  1V5Z A;  4QLY A;  2ISK A;  2FRE A;  3GR3 A;  4XOM A;  4G8S A;  1YKI A;  3GH8 A;  2HAY A;  4XOO A;  2IFA A;  3G14 A;  1IDT A;  1KQC A;  5KRD A;  3GBH A;  3GAG A;  1ICV A;  3BM1 A;  3K6H A;  1OO6 A;  3GB5 A;  2WZW A;  1YLR A;  1BKJ A;  2ISL A;  3KWK A;  4BN9 A;  1ICR A;  3E10 A;  1DS7 A;  3EK3 A;  1VFR A;  4EO3 A;  4URP A;  4DN2 A;  3GFD A;  1VKW A;  1OO5 A;  4QLX A;  1ICU A;  1NOX A;  2BKJ A;  2I7H A;  3KOQ A;  2ISJ A;  3HJ9 A;  2WQF A;  1OOQ A;  1J6R A;  1ZCH A;  4TTB A;  1YLU A;  3EO8 A;  1KQB A;  3TO0 A;  2R01 A;  2YMV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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