3IOLA

Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
100
structure length
100
Chain Sequence
TVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor
pubmed doi rcsb
molecule tags Signaling protein/signaling protein
source organism Homo sapiens
molecule keywords Glucagon-like peptide 1 receptor
total genus 22
structure length 100
sequence length 100
ec nomenclature
pdb deposition date 2009-08-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02793 HRM Hormone receptor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.1240.10 Few Secondary Structures Irregular Hormone receptor fold GPCR, family 2, extracellular hormone receptor domain 3iolA00
3AQFB 3C4MA 3N7RA 3N7PA 3EHSA 2L27A 3IOLA 4ZGMA 4ERSA 3N7SA 3L2JA 3C59A 2JODA 2JNCA 5II0A 2QKHA 2XDGA 3EHTA 4LF3C 2JNDA 4DLQA 3H3GA 3EHUA 4DLOA 1U34A 3C5TA 4HJ0A
chains in the Genus database with same CATH superfamily
3AQFB 3C4MA 3N7RA 3N7PA 3EHSA 2L27A 3IOLA 4ZGMA 4ERSA 3N7SA 3L2JA 3C59A 2JODA 2JNCA 5II0A 2QKHA 2XDGA 3EHTA 4LF3C 2JNDA 4DLQA 3H3GA 3EHUA 4DLOA 1U34A 3C5TA 4HJ0A
chains in the Genus database with same CATH topology
3AQFB 3C4MA 3N7RA 3N7PA 3EHSA 2L27A 3IOLA 4ZGMA 4ERSA 3N7SA 3L2JA 3C59A 2JODA 2JNCA 5II0A 2QKHA 2XDGA 3EHTA 4LF3C 2JNDA 4DLQA 3H3GA 3EHUA 4DLOA 1U34A 3C5TA 4HJ0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AQF B;  3C4M A;  3N7R A;  3N7P A;  3EHS A;  2L27 A;  3IOL A;  4ZGM A;  4ERS A;  3N7S A;  3L2J A;  3C59 A;  2JOD A;  2JNC A;  5II0 A;  2QKH A;  2XDG A;  3EHT A;  4LF3 C;  2JND A;  4DLQ A;  3H3G A;  3EHU A;  4DLO A;  1U34 A;  3C5T A;  4HJ0 A; 
#chains in the Genus database with same CATH topology
 3AQF B;  3C4M A;  3N7R A;  3N7P A;  3EHS A;  2L27 A;  3IOL A;  4ZGM A;  4ERS A;  3N7S A;  3L2J A;  3C59 A;  2JOD A;  2JNC A;  5II0 A;  2QKH A;  2XDG A;  3EHT A;  4LF3 C;  2JND A;  4DLQ A;  3H3G A;  3EHU A;  4DLO A;  1U34 A;  3C5T A;  4HJ0 A; 
#chains in the Genus database with same CATH homology
 3AQF B;  3C4M A;  3N7R A;  3N7P A;  3EHS A;  2L27 A;  3IOL A;  4ZGM A;  4ERS A;  3N7S A;  3L2J A;  3C59 A;  2JOD A;  2JNC A;  5II0 A;  2QKH A;  2XDG A;  3EHT A;  4LF3 C;  2JND A;  4DLQ A;  3H3G A;  3EHU A;  4DLO A;  1U34 A;  3C5T A;  4HJ0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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