3KRWG

Human grk2 in complex with gbetgamma subunits and balanol (soak)
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
60
structure length
60
Chain Sequence
SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of human g protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Beta-adrenergic receptor kinase 1
total genus 15
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 2009-11-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 3krwG00
3AH8G 3CIKG 5HE1G 4MK0G 1GG2G 1TBGE 1GOTG 1A0RG 3SN6G 5HE3G 5HE2G 4KFMG 5HE0G 2BCJG 1B9XB 2TRCG 5TDHG 5KDOG 1OMWG 3PVWG 2PBIA 3KRWG 3V5WG 1XHMB 3KRXG 4PNKG 1B9YB 3PVUG 1GP2G 3PSCG
chains in the Genus database with same CATH superfamily
3AH8G 3CIKG 1HFES 5HE1G 4MK0G 1GG2G 1TBGE 1GOTG 1A0RG 3SN6G 5HE3G 5HE2G 4KFMG 5HE0G 2BCJG 1B9XB 2TRCG 5TDHG 5KDOG 1IOJA 1OMWG 3PVWG 2PBIA 3KRWG 3V5WG 1XHMB 3KRXG 4PNKG 1B9YB 3PVUG 1GP2G 3PSCG
chains in the Genus database with same CATH topology
3AH8G 3CIKG 5HE1G 4MK0G 1GG2G 1TBGE 1GOTG 1A0RG 3SN6G 5HE3G 5HE2G 4KFMG 5HE0G 2BCJG 1B9XB 2TRCG 5TDHG 5KDOG 1OMWG 3PVWG 2PBIA 3KRWG 3V5WG 1XHMB 3KRXG 4PNKG 1B9YB 3PVUG 1GP2G 3PSCG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AH8 G;  3CIK G;  5HE1 G;  4MK0 G;  1GG2 G;  1TBG E;  1GOT G;  1A0R G;  3SN6 G;  5HE3 G;  5HE2 G;  4KFM G;  5HE0 G;  2BCJ G;  1B9X B;  2TRC G;  5TDH G;  5KDO G;  1OMW G;  3PVW G;  2PBI A;  3KRW G;  3V5W G;  1XHM B;  3KRX G;  4PNK G;  1B9Y B;  3PVU G;  1GP2 G;  3PSC G; 
#chains in the Genus database with same CATH topology
 3AH8 G;  3CIK G;  1HFE S;  5HE1 G;  4MK0 G;  1GG2 G;  1TBG E;  1GOT G;  1A0R G;  3SN6 G;  5HE3 G;  5HE2 G;  4KFM G;  5HE0 G;  2BCJ G;  1B9X B;  2TRC G;  5TDH G;  5KDO G;  1IOJ A;  1OMW G;  3PVW G;  2PBI A;  3KRW G;  3V5W G;  1XHM B;  3KRX G;  4PNK G;  1B9Y B;  3PVU G;  1GP2 G;  3PSC G; 
#chains in the Genus database with same CATH homology
 3AH8 G;  3CIK G;  5HE1 G;  4MK0 G;  1GG2 G;  1TBG E;  1GOT G;  1A0R G;  3SN6 G;  5HE3 G;  5HE2 G;  4KFM G;  5HE0 G;  2BCJ G;  1B9X B;  2TRC G;  5TDH G;  5KDO G;  1OMW G;  3PVW G;  2PBI A;  3KRW G;  3V5W G;  1XHM B;  3KRX G;  4PNK G;  1B9Y B;  3PVU G;  1GP2 G;  3PSC G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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