3KRXG

Human grk2 in complex with gbetgamma subunits and balanol (co-crystal)
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
60
structure length
60
Chain Sequence
SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of human g protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Beta-adrenergic receptor kinase 1
total genus 13
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 2009-11-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 3krxG00
1A0RG 1B9XB 5HE1G 5HE3G 1XHMB 5HE2G 4KFMG 5KDOG 5HE0G 3KRWG 3KRXG 3PVWG 3SN6G 1GP2G 1TBGE 2BCJG 3AH8G 5TDHG 2PBIA 1B9YB 3PVUG 1GG2G 4PNKG 3V5WG 4MK0G 1GOTG 2TRCG 3CIKG 3PSCG 1OMWG
chains in the Genus database with same CATH superfamily
1A0RG 1B9XB 5HE1G 1HFES 5HE3G 1XHMB 5HE2G 4KFMG 5KDOG 5HE0G 3KRWG 3KRXG 3PVWG 3SN6G 1IOJA 1GP2G 1TBGE 2BCJG 3AH8G 5TDHG 2PBIA 1B9YB 3PVUG 1GG2G 4PNKG 3V5WG 4MK0G 1GOTG 2TRCG 3CIKG 3PSCG 1OMWG
chains in the Genus database with same CATH topology
1A0RG 1B9XB 5HE1G 5HE3G 1XHMB 5HE2G 4KFMG 5KDOG 5HE0G 3KRWG 3KRXG 3PVWG 3SN6G 1GP2G 1TBGE 2BCJG 3AH8G 5TDHG 2PBIA 1B9YB 3PVUG 1GG2G 4PNKG 3V5WG 4MK0G 1GOTG 2TRCG 3CIKG 3PSCG 1OMWG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A0R G;  1B9X B;  5HE1 G;  5HE3 G;  1XHM B;  5HE2 G;  4KFM G;  5KDO G;  5HE0 G;  3KRW G;  3KRX G;  3PVW G;  3SN6 G;  1GP2 G;  1TBG E;  2BCJ G;  3AH8 G;  5TDH G;  2PBI A;  1B9Y B;  3PVU G;  1GG2 G;  4PNK G;  3V5W G;  4MK0 G;  1GOT G;  2TRC G;  3CIK G;  3PSC G;  1OMW G; 
#chains in the Genus database with same CATH topology
 1A0R G;  1B9X B;  5HE1 G;  1HFE S;  5HE3 G;  1XHM B;  5HE2 G;  4KFM G;  5KDO G;  5HE0 G;  3KRW G;  3KRX G;  3PVW G;  3SN6 G;  1IOJ A;  1GP2 G;  1TBG E;  2BCJ G;  3AH8 G;  5TDH G;  2PBI A;  1B9Y B;  3PVU G;  1GG2 G;  4PNK G;  3V5W G;  4MK0 G;  1GOT G;  2TRC G;  3CIK G;  3PSC G;  1OMW G; 
#chains in the Genus database with same CATH homology
 1A0R G;  1B9X B;  5HE1 G;  5HE3 G;  1XHM B;  5HE2 G;  4KFM G;  5KDO G;  5HE0 G;  3KRW G;  3KRX G;  3PVW G;  3SN6 G;  1GP2 G;  1TBG E;  2BCJ G;  3AH8 G;  5TDH G;  2PBI A;  1B9Y B;  3PVU G;  1GG2 G;  4PNK G;  3V5W G;  4MK0 G;  1GOT G;  2TRC G;  3CIK G;  3PSC G;  1OMW G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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