3LL0A

Monomeric griffithsin with two gly-ser insertions
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
125
structure length
125
Chain Sequence
SLTHRKFGGSGGSPFSGSGSGLSSIAVRSGSYLDAIIIDGVHHGGSGGNLSPTFTFGSGEYISNMTIRSGDYIDNISFETNMGRRFGPYGGSGGSANTLSNVKVIQINGSAGDYLDSLDIYYEQY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Griffithsia
molecule keywords Griffithsin
total genus 23
structure length 125
sequence length 125
ec nomenclature
pdb deposition date 2010-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01419 Jacalin Jacalin-like lectin domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.100.10.30 Mainly Beta Aligned Prism Vitelline Membrane Outer Layer Protein I, subunit A Jacalin-like lectin domain 3ll0A00
2GTYA 4R6RA 1C3NA 1TOQA 4AKDA 1J4UA 4DDNA 3APAA 1XXQA 3VY7A 4R6QA 3O44A 1WS5C 3LL1A 1UGYA 1UGWC 1KUJA 1XXRA 2GUDA 3LLYA 1C3KA 3LM1A 2NU5A 1X1VA 1WS4A 5J51A 4R6OA 4MQ0A 1UGYC 3R51A 3VZGA 3P8SA 2GUEA 4AKBA 2GUCA 1VBOA 3LKYA 1WS4C 2NUOA 3VZEA 1M26A 5BN6E 3LL0A 1C3MA 3LL2A 2HYQA 1OUWA 1JACA 4AK4A 4GX7A 5JM1A 1KU8A 3WOBA 1ZGRA 3VY6A 1WS5A 2JZ4A 3AQGA 1PXDA 5J50A 3WOCA 3MITA 3MIVA 1UGXA 1XEZA 3MIUA 5EXGA 4PITA 4R6PA 1JOTA 3LLZA 5J4XA 4PIFA 4R6NA 4AKCA 2BMYA 5J4TA 2HYRA 2BMZA 1J4TA 3VZFA 1ZGSA 4PIKA 2BN0A 1TP8A 3R50A 2GUXA 1J4SA 1UGWA 1VBPA 1UH1A 5AV7A 4PIUA 4WOGA 3R52A 1UH0A
chains in the Genus database with same CATH superfamily
2GTYA 4R6RA 1C3NA 1TOQA 4AKDA 1J4UA 4DDNA 3APAA 1XXQA 3VY7A 4R6QA 3O44A 1WS5C 3LL1A 1UGYA 1UGWC 1JI6A 1KUJA 1XXRA 2GUDA 1CIYA 3LLYA 4QX2A 1C3KA 3LM1A 2NU5A 1X1VA 1WS4A 5J51A 4R6OA 4MQ0A 1UGYC 3R51A 3VZGA 3P8SA 2GUEA 3TOWA 4ARXA 4AKBA 2GUCA 1VBOA 1W99A 3EB7A 3LKYA 1WS4C 2NUOA 3VZEA 2C9KA 2QP2A 5BN6E 1M26A 3LL0A 1C3MA 3LL2A 4ARYA 2HYQA 1OUWA 1JACA 4AK4A 1I5PA 4GX7A 5JM1A 1KU8A 3WOBA 1ZGRA 4QX3A 3VY6A 1WS5A 2JZ4A 3AQGA 1PXDA 5J50A 3WOCA 3MITA 3MIVA 1UGXA 1XEZA 3MIUA 5EXGA 4PITA 4R6PA 4QX0A 1JOTA 3LLZA 5J4XA 4PIFA 4MOAA 4R6NA 4AKCA 2BMYA 5J4TA 2HYRA 4QX1A 2BMZA 1J4TA 3VZFA 1VMOA 1DLCA 1ZGSA 4PIKA 4D8MA 2BN0A 1TP8A 3R50A 2GUXA 1J4SA 1UGWA 4W8JA 1VBPA 1UH1A 5AV7A 4PIUA 4WOGA 3R52A 1UH0A
chains in the Genus database with same CATH topology
2GTYA 4R6RA 1C3NA 1TOQA 4AKDA 1J4UA 4DDNA 3APAA 1XXQA 3VY7A 4R6QA 3O44A 1WS5C 3LL1A 1UGYA 1UGWC 1KUJA 1XXRA 2GUDA 3LLYA 1C3KA 3LM1A 2NU5A 1X1VA 1WS4A 5J51A 4R6OA 4MQ0A 1UGYC 3R51A 3VZGA 3P8SA 2GUEA 4AKBA 2GUCA 1VBOA 3LKYA 1WS4C 2NUOA 3VZEA 1M26A 5BN6E 3LL0A 1C3MA 3LL2A 2HYQA 1OUWA 1JACA 4AK4A 4GX7A 5JM1A 1KU8A 3WOBA 1ZGRA 3VY6A 1WS5A 2JZ4A 3AQGA 1PXDA 5J50A 3WOCA 3MITA 3MIVA 1UGXA 1XEZA 3MIUA 5EXGA 4PITA 4R6PA 1JOTA 3LLZA 5J4XA 4PIFA 4R6NA 4AKCA 2BMYA 5J4TA 2HYRA 2BMZA 1J4TA 3VZFA 1ZGSA 4PIKA 2BN0A 1TP8A 3R50A 2GUXA 1J4SA 1UGWA 1VBPA 1UH1A 5AV7A 4PIUA 4WOGA 3R52A 1UH0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GTY A;  4R6R A;  1C3N A;  1TOQ A;  4AKD A;  1J4U A;  4DDN A;  3APA A;  1XXQ A;  3VY7 A;  4R6Q A;  3O44 A;  1WS5 C;  3LL1 A;  1UGY A;  1UGW C;  1KUJ A;  1XXR A;  2GUD A;  3LLY A;  1C3K A;  3LM1 A;  2NU5 A;  1X1V A;  1WS4 A;  5J51 A;  4R6O A;  4MQ0 A;  1UGY C;  3R51 A;  3VZG A;  3P8S A;  2GUE A;  4AKB A;  2GUC A;  1VBO A;  3LKY A;  1WS4 C;  2NUO A;  3VZE A;  1M26 A;  5BN6 E;  3LL0 A;  1C3M A;  3LL2 A;  2HYQ A;  1OUW A;  1JAC A;  4AK4 A;  4GX7 A;  5JM1 A;  1KU8 A;  3WOB A;  1ZGR A;  3VY6 A;  1WS5 A;  2JZ4 A;  3AQG A;  1PXD A;  5J50 A;  3WOC A;  3MIT A;  3MIV A;  1UGX A;  1XEZ A;  3MIU A;  5EXG A;  4PIT A;  4R6P A;  1JOT A;  3LLZ A;  5J4X A;  4PIF A;  4R6N A;  4AKC A;  2BMY A;  5J4T A;  2HYR A;  2BMZ A;  1J4T A;  3VZF A;  1ZGS A;  4PIK A;  2BN0 A;  1TP8 A;  3R50 A;  2GUX A;  1J4S A;  1UGW A;  1VBP A;  1UH1 A;  5AV7 A;  4PIU A;  4WOG A;  3R52 A;  1UH0 A; 
#chains in the Genus database with same CATH topology
 2GTY A;  4R6R A;  1C3N A;  1TOQ A;  4AKD A;  1J4U A;  4DDN A;  3APA A;  1XXQ A;  3VY7 A;  4R6Q A;  3O44 A;  1WS5 C;  3LL1 A;  1UGY A;  1UGW C;  1JI6 A;  1KUJ A;  1XXR A;  2GUD A;  1CIY A;  3LLY A;  4QX2 A;  1C3K A;  3LM1 A;  2NU5 A;  1X1V A;  1WS4 A;  5J51 A;  4R6O A;  4MQ0 A;  1UGY C;  3R51 A;  3VZG A;  3P8S A;  2GUE A;  3TOW A;  4ARX A;  4AKB A;  2GUC A;  1VBO A;  1W99 A;  3EB7 A;  3LKY A;  1WS4 C;  2NUO A;  3VZE A;  2C9K A;  2QP2 A;  5BN6 E;  1M26 A;  3LL0 A;  1C3M A;  3LL2 A;  4ARY A;  2HYQ A;  1OUW A;  1JAC A;  4AK4 A;  1I5P A;  4GX7 A;  5JM1 A;  1KU8 A;  3WOB A;  1ZGR A;  4QX3 A;  3VY6 A;  1WS5 A;  2JZ4 A;  3AQG A;  1PXD A;  5J50 A;  3WOC A;  3MIT A;  3MIV A;  1UGX A;  1XEZ A;  3MIU A;  5EXG A;  4PIT A;  4R6P A;  4QX0 A;  1JOT A;  3LLZ A;  5J4X A;  4PIF A;  4MOA A;  4R6N A;  4AKC A;  2BMY A;  5J4T A;  2HYR A;  4QX1 A;  2BMZ A;  1J4T A;  3VZF A;  1VMO A;  1DLC A;  1ZGS A;  4PIK A;  4D8M A;  2BN0 A;  1TP8 A;  3R50 A;  2GUX A;  1J4S A;  1UGW A;  4W8J A;  1VBP A;  1UH1 A;  5AV7 A;  4PIU A;  4WOG A;  3R52 A;  1UH0 A; 
#chains in the Genus database with same CATH homology
 2GTY A;  4R6R A;  1C3N A;  1TOQ A;  4AKD A;  1J4U A;  4DDN A;  3APA A;  1XXQ A;  3VY7 A;  4R6Q A;  3O44 A;  1WS5 C;  3LL1 A;  1UGY A;  1UGW C;  1KUJ A;  1XXR A;  2GUD A;  3LLY A;  1C3K A;  3LM1 A;  2NU5 A;  1X1V A;  1WS4 A;  5J51 A;  4R6O A;  4MQ0 A;  1UGY C;  3R51 A;  3VZG A;  3P8S A;  2GUE A;  4AKB A;  2GUC A;  1VBO A;  3LKY A;  1WS4 C;  2NUO A;  3VZE A;  1M26 A;  5BN6 E;  3LL0 A;  1C3M A;  3LL2 A;  2HYQ A;  1OUW A;  1JAC A;  4AK4 A;  4GX7 A;  5JM1 A;  1KU8 A;  3WOB A;  1ZGR A;  3VY6 A;  1WS5 A;  2JZ4 A;  3AQG A;  1PXD A;  5J50 A;  3WOC A;  3MIT A;  3MIV A;  1UGX A;  1XEZ A;  3MIU A;  5EXG A;  4PIT A;  4R6P A;  1JOT A;  3LLZ A;  5J4X A;  4PIF A;  4R6N A;  4AKC A;  2BMY A;  5J4T A;  2HYR A;  2BMZ A;  1J4T A;  3VZF A;  1ZGS A;  4PIK A;  2BN0 A;  1TP8 A;  3R50 A;  2GUX A;  1J4S A;  1UGW A;  1VBP A;  1UH1 A;  5AV7 A;  4PIU A;  4WOG A;  3R52 A;  1UH0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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