3LL1A

Monomeric griffithsin with a single gly-ser insertion and mutations to remove residual self-association
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
122
structure length
122
Chain Sequence
SSTHRKFGGSGGSPFSGSGLSSIAVRSGSYLDAIIIDGVHHGGSGGNLSPTFTFGSGEYISNMTIRSGDYIDNISFETNMGRRFGPYGGSGGSANTLSNVKVIQINGSAGDYLDSLDIYYDN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Griffithsia
molecule keywords Griffithsin
total genus 23
structure length 122
sequence length 122
ec nomenclature
pdb deposition date 2010-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01419 Jacalin Jacalin-like lectin domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.100.10.30 Mainly Beta Aligned Prism Vitelline Membrane Outer Layer Protein I, subunit A Jacalin-like lectin domain 3ll1A00
1XXQA 5EXGA 3APAA 4AKDA 1J4TA 1JOTA 3R52A 3LLZA 3LL1A 1C3NA 4PIFA 1J4UA 1J4SA 1X1VA 2GUDA 5J4TA 5BN6E 3VZGA 2NU5A 5J4XA 5J51A 3P8SA 5AV7A 1XXRA 3LKYA 1ZGSA 4AKCA 1UGYC 1UH1A 4R6PA 4PIUA 4WOGA 1WS4A 1TP8A 3AQGA 3LL0A 1VBOA 1ZGRA 1UGWC 1UGYA 1XEZA 2GUEA 1WS4C 1C3MA 4GX7A 1UGWA 1PXDA 5JM1A 4R6NA 3LL2A 3VY7A 2BN0A 3R51A 3LM1A 2HYQA 2GUCA 1OUWA 5J50A 4DDNA 4AK4A 1KU8A 1UH0A 1VBPA 3O44A 1KUJA 4PIKA 2GTYA 2JZ4A 2BMZA 4MQ0A 4R6QA 4R6RA 3MITA 1M26A 2GUXA 2HYRA 3VZEA 3MIVA 1JACA 1UGXA 1WS5C 4AKBA 1C3KA 3WOBA 3VZFA 3LLYA 3VY6A 2BMYA 3WOCA 1TOQA 3MIUA 3R50A 1WS5A 2NUOA 4R6OA 4PITA
chains in the Genus database with same CATH superfamily
1XXQA 4W8JA 4MOAA 5EXGA 3APAA 4AKDA 1J4TA 1JOTA 1DLCA 3R52A 3LLZA 3LL1A 1C3NA 4PIFA 1J4UA 1J4SA 4QX0A 1X1VA 2GUDA 5J4TA 5BN6E 3VZGA 2NU5A 5J4XA 5J51A 3P8SA 4QX3A 5AV7A 1XXRA 4QX1A 3LKYA 1ZGSA 3EB7A 4AKCA 1UGYC 1UH1A 4R6PA 4PIUA 4WOGA 1WS4A 1TP8A 3AQGA 3LL0A 1VBOA 1ZGRA 1UGWC 1UGYA 1XEZA 2GUEA 1WS4C 1C3MA 1I5PA 4GX7A 1UGWA 1PXDA 1W99A 4ARXA 5JM1A 4R6NA 3LL2A 3VY7A 2QP2A 2BN0A 3R51A 3LM1A 2HYQA 2GUCA 1OUWA 5J50A 4DDNA 4AK4A 1CIYA 1KU8A 1UH0A 1VBPA 3O44A 1KUJA 4PIKA 3TOWA 2GTYA 2C9KA 2JZ4A 2BMZA 4MQ0A 4R6QA 4R6RA 1JI6A 3MITA 1M26A 2GUXA 2HYRA 3VZEA 3MIVA 1JACA 1UGXA 1WS5C 4AKBA 1C3KA 3WOBA 3VZFA 4QX2A 3LLYA 1VMOA 3VY6A 2BMYA 3WOCA 1TOQA 3MIUA 3R50A 1WS5A 2NUOA 4R6OA 4D8MA 4ARYA 4PITA
chains in the Genus database with same CATH topology
1XXQA 5EXGA 3APAA 4AKDA 1J4TA 1JOTA 3R52A 3LLZA 3LL1A 1C3NA 4PIFA 1J4UA 1J4SA 1X1VA 2GUDA 5J4TA 5BN6E 3VZGA 2NU5A 5J4XA 5J51A 3P8SA 5AV7A 1XXRA 3LKYA 1ZGSA 4AKCA 1UGYC 1UH1A 4R6PA 4PIUA 4WOGA 1WS4A 1TP8A 3AQGA 3LL0A 1VBOA 1ZGRA 1UGWC 1UGYA 1XEZA 2GUEA 1WS4C 1C3MA 4GX7A 1UGWA 1PXDA 5JM1A 4R6NA 3LL2A 3VY7A 2BN0A 3R51A 3LM1A 2HYQA 2GUCA 1OUWA 5J50A 4DDNA 4AK4A 1KU8A 1UH0A 1VBPA 3O44A 1KUJA 4PIKA 2GTYA 2JZ4A 2BMZA 4MQ0A 4R6QA 4R6RA 3MITA 1M26A 2GUXA 2HYRA 3VZEA 3MIVA 1JACA 1UGXA 1WS5C 4AKBA 1C3KA 3WOBA 3VZFA 3LLYA 3VY6A 2BMYA 3WOCA 1TOQA 3MIUA 3R50A 1WS5A 2NUOA 4R6OA 4PITA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XXQ A;  5EXG A;  3APA A;  4AKD A;  1J4T A;  1JOT A;  3R52 A;  3LLZ A;  3LL1 A;  1C3N A;  4PIF A;  1J4U A;  1J4S A;  1X1V A;  2GUD A;  5J4T A;  5BN6 E;  3VZG A;  2NU5 A;  5J4X A;  5J51 A;  3P8S A;  5AV7 A;  1XXR A;  3LKY A;  1ZGS A;  4AKC A;  1UGY C;  1UH1 A;  4R6P A;  4PIU A;  4WOG A;  1WS4 A;  1TP8 A;  3AQG A;  3LL0 A;  1VBO A;  1ZGR A;  1UGW C;  1UGY A;  1XEZ A;  2GUE A;  1WS4 C;  1C3M A;  4GX7 A;  1UGW A;  1PXD A;  5JM1 A;  4R6N A;  3LL2 A;  3VY7 A;  2BN0 A;  3R51 A;  3LM1 A;  2HYQ A;  2GUC A;  1OUW A;  5J50 A;  4DDN A;  4AK4 A;  1KU8 A;  1UH0 A;  1VBP A;  3O44 A;  1KUJ A;  4PIK A;  2GTY A;  2JZ4 A;  2BMZ A;  4MQ0 A;  4R6Q A;  4R6R A;  3MIT A;  1M26 A;  2GUX A;  2HYR A;  3VZE A;  3MIV A;  1JAC A;  1UGX A;  1WS5 C;  4AKB A;  1C3K A;  3WOB A;  3VZF A;  3LLY A;  3VY6 A;  2BMY A;  3WOC A;  1TOQ A;  3MIU A;  3R50 A;  1WS5 A;  2NUO A;  4R6O A;  4PIT A; 
#chains in the Genus database with same CATH topology
 1XXQ A;  4W8J A;  4MOA A;  5EXG A;  3APA A;  4AKD A;  1J4T A;  1JOT A;  1DLC A;  3R52 A;  3LLZ A;  3LL1 A;  1C3N A;  4PIF A;  1J4U A;  1J4S A;  4QX0 A;  1X1V A;  2GUD A;  5J4T A;  5BN6 E;  3VZG A;  2NU5 A;  5J4X A;  5J51 A;  3P8S A;  4QX3 A;  5AV7 A;  1XXR A;  4QX1 A;  3LKY A;  1ZGS A;  3EB7 A;  4AKC A;  1UGY C;  1UH1 A;  4R6P A;  4PIU A;  4WOG A;  1WS4 A;  1TP8 A;  3AQG A;  3LL0 A;  1VBO A;  1ZGR A;  1UGW C;  1UGY A;  1XEZ A;  2GUE A;  1WS4 C;  1C3M A;  1I5P A;  4GX7 A;  1UGW A;  1PXD A;  1W99 A;  4ARX A;  5JM1 A;  4R6N A;  3LL2 A;  3VY7 A;  2QP2 A;  2BN0 A;  3R51 A;  3LM1 A;  2HYQ A;  2GUC A;  1OUW A;  5J50 A;  4DDN A;  4AK4 A;  1CIY A;  1KU8 A;  1UH0 A;  1VBP A;  3O44 A;  1KUJ A;  4PIK A;  3TOW A;  2GTY A;  2C9K A;  2JZ4 A;  2BMZ A;  4MQ0 A;  4R6Q A;  4R6R A;  1JI6 A;  3MIT A;  1M26 A;  2GUX A;  2HYR A;  3VZE A;  3MIV A;  1JAC A;  1UGX A;  1WS5 C;  4AKB A;  1C3K A;  3WOB A;  3VZF A;  4QX2 A;  3LLY A;  1VMO A;  3VY6 A;  2BMY A;  3WOC A;  1TOQ A;  3MIU A;  3R50 A;  1WS5 A;  2NUO A;  4R6O A;  4D8M A;  4ARY A;  4PIT A; 
#chains in the Genus database with same CATH homology
 1XXQ A;  5EXG A;  3APA A;  4AKD A;  1J4T A;  1JOT A;  3R52 A;  3LLZ A;  3LL1 A;  1C3N A;  4PIF A;  1J4U A;  1J4S A;  1X1V A;  2GUD A;  5J4T A;  5BN6 E;  3VZG A;  2NU5 A;  5J4X A;  5J51 A;  3P8S A;  5AV7 A;  1XXR A;  3LKY A;  1ZGS A;  4AKC A;  1UGY C;  1UH1 A;  4R6P A;  4PIU A;  4WOG A;  1WS4 A;  1TP8 A;  3AQG A;  3LL0 A;  1VBO A;  1ZGR A;  1UGW C;  1UGY A;  1XEZ A;  2GUE A;  1WS4 C;  1C3M A;  4GX7 A;  1UGW A;  1PXD A;  5JM1 A;  4R6N A;  3LL2 A;  3VY7 A;  2BN0 A;  3R51 A;  3LM1 A;  2HYQ A;  2GUC A;  1OUW A;  5J50 A;  4DDN A;  4AK4 A;  1KU8 A;  1UH0 A;  1VBP A;  3O44 A;  1KUJ A;  4PIK A;  2GTY A;  2JZ4 A;  2BMZ A;  4MQ0 A;  4R6Q A;  4R6R A;  3MIT A;  1M26 A;  2GUX A;  2HYR A;  3VZE A;  3MIV A;  1JAC A;  1UGX A;  1WS5 C;  4AKB A;  1C3K A;  3WOB A;  3VZF A;  3LLY A;  3VY6 A;  2BMY A;  3WOC A;  1TOQ A;  3MIU A;  3R50 A;  1WS5 A;  2NUO A;  4R6O A;  4PIT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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