3LL2A

Monomeric griffithsin in complex with a high-mannose branched carbohydrate
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
123
structure length
123
Chain Sequence
SSTHRKFGGSGGSPFSGSGLSSIAVRSGSYLDAIIIDGVHHGGSGGNLSPTFTFGSGEYISNMTIRSGDYIDNISFETNMGRRFGPYGGSGGSANTLSNVKVIQINGSAGDYLDSLDIYYEQY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Griffithsia
molecule keywords Griffithsin
total genus 25
structure length 123
sequence length 123
ec nomenclature
pdb deposition date 2010-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01419 Jacalin Jacalin-like lectin domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.100.10.30 Mainly Beta Aligned Prism Vitelline Membrane Outer Layer Protein I, subunit A Jacalin-like lectin domain 3ll2A00
4R6PA 2GTYA 4AKDA 3MITA 5J51A 1ZGRA 3MIUA 1C3NA 4PITA 2NUOA 2BN0A 5J4XA 1X1VA 3WOCA 1J4TA 1JACA 2HYQA 1WS4C 4DDNA 1M26A 1UH0A 4AKCA 1VBPA 1UH1A 1TP8A 2GUDA 1UGWC 3VZEA 4WOGA 2JZ4A 3LLYA 1WS5A 2BMYA 3R52A 4R6NA 3VY7A 3R50A 1C3KA 2HYRA 4AKBA 3VZFA 2GUXA 1WS4A 4R6RA 2BMZA 3O44A 5J50A 3APAA 1XEZA 1UGWA 2GUCA 5JM1A 1UGYC 1PXDA 4PIKA 3P8SA 1XXQA 3WOBA 3LL2A 4PIFA 4MQ0A 4GX7A 1J4UA 3LKYA 3R51A 5EXGA 1VBOA 1XXRA 1KU8A 3VY6A 5BN6E 1UGXA 4PIUA 3LL1A 1TOQA 2GUEA 1ZGSA 3AQGA 3LM1A 1C3MA 3MIVA 1J4SA 3LL0A 5J4TA 3VZGA 1OUWA 2NU5A 4R6OA 1UGYA 1KUJA 5AV7A 3LLZA 1WS5C 4AK4A 1JOTA 4R6QA
chains in the Genus database with same CATH superfamily
4R6PA 2GTYA 2QP2A 4AKDA 3MITA 5J51A 1ZGRA 3MIUA 1C3NA 4PITA 4QX0A 2NUOA 4QX3A 2BN0A 5J4XA 1X1VA 3WOCA 1J4TA 1JACA 2HYQA 1WS4C 4DDNA 1I5PA 1M26A 1UH0A 4AKCA 1VMOA 1VBPA 1UH1A 1CIYA 1TP8A 2GUDA 1UGWC 3VZEA 4WOGA 2JZ4A 2C9KA 3LLYA 1WS5A 2BMYA 3R52A 4R6NA 3VY7A 3R50A 1C3KA 3EB7A 4D8MA 2HYRA 4AKBA 3VZFA 2GUXA 1WS4A 4R6RA 1W99A 2BMZA 3O44A 5J50A 3APAA 4MOAA 1XEZA 1UGWA 2GUCA 5JM1A 1UGYC 1PXDA 4W8JA 4PIKA 3P8SA 1XXQA 3WOBA 3LL2A 4ARXA 4PIFA 4MQ0A 4GX7A 1J4UA 3LKYA 3R51A 5EXGA 1VBOA 1XXRA 1JI6A 1KU8A 3VY6A 5BN6E 1UGXA 4PIUA 3TOWA 3LL1A 1TOQA 2GUEA 1ZGSA 3AQGA 3LM1A 1DLCA 1C3MA 4QX1A 3MIVA 1J4SA 3LL0A 4ARYA 5J4TA 3VZGA 1OUWA 2NU5A 4R6OA 1UGYA 1KUJA 4QX2A 5AV7A 3LLZA 1WS5C 4AK4A 1JOTA 4R6QA
chains in the Genus database with same CATH topology
4R6PA 2GTYA 4AKDA 3MITA 5J51A 1ZGRA 3MIUA 1C3NA 4PITA 2NUOA 2BN0A 5J4XA 1X1VA 3WOCA 1J4TA 1JACA 2HYQA 1WS4C 4DDNA 1M26A 1UH0A 4AKCA 1VBPA 1UH1A 1TP8A 2GUDA 1UGWC 3VZEA 4WOGA 2JZ4A 3LLYA 1WS5A 2BMYA 3R52A 4R6NA 3VY7A 3R50A 1C3KA 2HYRA 4AKBA 3VZFA 2GUXA 1WS4A 4R6RA 2BMZA 3O44A 5J50A 3APAA 1XEZA 1UGWA 2GUCA 5JM1A 1UGYC 1PXDA 4PIKA 3P8SA 1XXQA 3WOBA 3LL2A 4PIFA 4MQ0A 4GX7A 1J4UA 3LKYA 3R51A 5EXGA 1VBOA 1XXRA 1KU8A 3VY6A 5BN6E 1UGXA 4PIUA 3LL1A 1TOQA 2GUEA 1ZGSA 3AQGA 3LM1A 1C3MA 3MIVA 1J4SA 3LL0A 5J4TA 3VZGA 1OUWA 2NU5A 4R6OA 1UGYA 1KUJA 5AV7A 3LLZA 1WS5C 4AK4A 1JOTA 4R6QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4R6P A;  2GTY A;  4AKD A;  3MIT A;  5J51 A;  1ZGR A;  3MIU A;  1C3N A;  4PIT A;  2NUO A;  2BN0 A;  5J4X A;  1X1V A;  3WOC A;  1J4T A;  1JAC A;  2HYQ A;  1WS4 C;  4DDN A;  1M26 A;  1UH0 A;  4AKC A;  1VBP A;  1UH1 A;  1TP8 A;  2GUD A;  1UGW C;  3VZE A;  4WOG A;  2JZ4 A;  3LLY A;  1WS5 A;  2BMY A;  3R52 A;  4R6N A;  3VY7 A;  3R50 A;  1C3K A;  2HYR A;  4AKB A;  3VZF A;  2GUX A;  1WS4 A;  4R6R A;  2BMZ A;  3O44 A;  5J50 A;  3APA A;  1XEZ A;  1UGW A;  2GUC A;  5JM1 A;  1UGY C;  1PXD A;  4PIK A;  3P8S A;  1XXQ A;  3WOB A;  3LL2 A;  4PIF A;  4MQ0 A;  4GX7 A;  1J4U A;  3LKY A;  3R51 A;  5EXG A;  1VBO A;  1XXR A;  1KU8 A;  3VY6 A;  5BN6 E;  1UGX A;  4PIU A;  3LL1 A;  1TOQ A;  2GUE A;  1ZGS A;  3AQG A;  3LM1 A;  1C3M A;  3MIV A;  1J4S A;  3LL0 A;  5J4T A;  3VZG A;  1OUW A;  2NU5 A;  4R6O A;  1UGY A;  1KUJ A;  5AV7 A;  3LLZ A;  1WS5 C;  4AK4 A;  1JOT A;  4R6Q A; 
#chains in the Genus database with same CATH topology
 4R6P A;  2GTY A;  2QP2 A;  4AKD A;  3MIT A;  5J51 A;  1ZGR A;  3MIU A;  1C3N A;  4PIT A;  4QX0 A;  2NUO A;  4QX3 A;  2BN0 A;  5J4X A;  1X1V A;  3WOC A;  1J4T A;  1JAC A;  2HYQ A;  1WS4 C;  4DDN A;  1I5P A;  1M26 A;  1UH0 A;  4AKC A;  1VMO A;  1VBP A;  1UH1 A;  1CIY A;  1TP8 A;  2GUD A;  1UGW C;  3VZE A;  4WOG A;  2JZ4 A;  2C9K A;  3LLY A;  1WS5 A;  2BMY A;  3R52 A;  4R6N A;  3VY7 A;  3R50 A;  1C3K A;  3EB7 A;  4D8M A;  2HYR A;  4AKB A;  3VZF A;  2GUX A;  1WS4 A;  4R6R A;  1W99 A;  2BMZ A;  3O44 A;  5J50 A;  3APA A;  4MOA A;  1XEZ A;  1UGW A;  2GUC A;  5JM1 A;  1UGY C;  1PXD A;  4W8J A;  4PIK A;  3P8S A;  1XXQ A;  3WOB A;  3LL2 A;  4ARX A;  4PIF A;  4MQ0 A;  4GX7 A;  1J4U A;  3LKY A;  3R51 A;  5EXG A;  1VBO A;  1XXR A;  1JI6 A;  1KU8 A;  3VY6 A;  5BN6 E;  1UGX A;  4PIU A;  3TOW A;  3LL1 A;  1TOQ A;  2GUE A;  1ZGS A;  3AQG A;  3LM1 A;  1DLC A;  1C3M A;  4QX1 A;  3MIV A;  1J4S A;  3LL0 A;  4ARY A;  5J4T A;  3VZG A;  1OUW A;  2NU5 A;  4R6O A;  1UGY A;  1KUJ A;  4QX2 A;  5AV7 A;  3LLZ A;  1WS5 C;  4AK4 A;  1JOT A;  4R6Q A; 
#chains in the Genus database with same CATH homology
 4R6P A;  2GTY A;  4AKD A;  3MIT A;  5J51 A;  1ZGR A;  3MIU A;  1C3N A;  4PIT A;  2NUO A;  2BN0 A;  5J4X A;  1X1V A;  3WOC A;  1J4T A;  1JAC A;  2HYQ A;  1WS4 C;  4DDN A;  1M26 A;  1UH0 A;  4AKC A;  1VBP A;  1UH1 A;  1TP8 A;  2GUD A;  1UGW C;  3VZE A;  4WOG A;  2JZ4 A;  3LLY A;  1WS5 A;  2BMY A;  3R52 A;  4R6N A;  3VY7 A;  3R50 A;  1C3K A;  2HYR A;  4AKB A;  3VZF A;  2GUX A;  1WS4 A;  4R6R A;  2BMZ A;  3O44 A;  5J50 A;  3APA A;  1XEZ A;  1UGW A;  2GUC A;  5JM1 A;  1UGY C;  1PXD A;  4PIK A;  3P8S A;  1XXQ A;  3WOB A;  3LL2 A;  4PIF A;  4MQ0 A;  4GX7 A;  1J4U A;  3LKY A;  3R51 A;  5EXG A;  1VBO A;  1XXR A;  1KU8 A;  3VY6 A;  5BN6 E;  1UGX A;  4PIU A;  3LL1 A;  1TOQ A;  2GUE A;  1ZGS A;  3AQG A;  3LM1 A;  1C3M A;  3MIV A;  1J4S A;  3LL0 A;  5J4T A;  3VZG A;  1OUW A;  2NU5 A;  4R6O A;  1UGY A;  1KUJ A;  5AV7 A;  3LLZ A;  1WS5 C;  4AK4 A;  1JOT A;  4R6Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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