3RWRA

Crystal structure of the human xrcc4-xlf complex
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
147
structure length
147
Chain Sequence
MERKISRIHLVSEPSITHFLQVSWEKTLESGFVITLTDGHSAWTGTVSESEISQEADDMAMEKGKYVGELRKALLSGAGPADVYTFNFSKESCYFFFEKNLKDVSFRLGSFNLEKVENPAEVIRELICYCLDTIAENQAKNEHLQKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of human XLF-XRCC4: assembly of a functional DNA repair complex
rcsb
molecule tags Dna binding protein/protein binding
source organism Homo sapiens
molecule keywords DNA repair protein XRCC4
total genus 23
structure length 147
sequence length 147
chains with identical sequence B, F, G, J, K, N, P, R, U, V, Y
ec nomenclature
pdb deposition date 2011-05-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.210.10 Mainly Beta Beta Complex Dna Repair Protein Xrcc4; Chain: A, domain 1 DNA double-strand break repair and VJ recombination XRCC4, N-terminal 3rwrA00
3RWRD 3SR2A 1IK9A 3MUDA 3II6A 2R9AA 2QM4A 3SR2C 5CJ4A 1FU1A 4XA4A 5CJ0A 3RWRA 5CHXA
chains in the Genus database with same CATH superfamily
4CKPA 4GEXA 1FU1A 4GFCA 4XA4A 4GFAA 3PYIA 1IK9A 3II6A 2R9AA 3Q0XA 2Y3VA 3Q0YA 4CKNA 4G79A 4GEUA 2Y3WA 5CJ0A 3RWRA 3RWRD 3SR2A 3MUDA 2QM4A 3SR2C 4CKMA 5CJ4A 5CHXA
chains in the Genus database with same CATH topology
3RWRD 3SR2A 1IK9A 3MUDA 3II6A 2R9AA 2QM4A 3SR2C 5CJ4A 1FU1A 4XA4A 5CJ0A 3RWRA 5CHXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RWR D;  3SR2 A;  1IK9 A;  3MUD A;  3II6 A;  2R9A A;  2QM4 A;  3SR2 C;  5CJ4 A;  1FU1 A;  4XA4 A;  5CJ0 A;  3RWR A;  5CHX A; 
#chains in the Genus database with same CATH topology
 4CKP A;  4GEX A;  1FU1 A;  4GFC A;  4XA4 A;  4GFA A;  3PYI A;  1IK9 A;  3II6 A;  2R9A A;  3Q0X A;  2Y3V A;  3Q0Y A;  4CKN A;  4G79 A;  4GEU A;  2Y3W A;  5CJ0 A;  3RWR A;  3RWR D;  3SR2 A;  3MUD A;  2QM4 A;  3SR2 C;  4CKM A;  5CJ4 A;  5CHX A; 
#chains in the Genus database with same CATH homology
 3RWR D;  3SR2 A;  1IK9 A;  3MUD A;  3II6 A;  2R9A A;  2QM4 A;  3SR2 C;  5CJ4 A;  1FU1 A;  4XA4 A;  5CJ0 A;  3RWR A;  5CHX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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