4ATIA

Mitf:m-box complex
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
61
structure length
57
Chain Sequence
HNLIERRRRFNINDRIKELGTLIPKSMRWNKGTILKASVDYIRKLQREQQRAKDLEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Restricted Leucine Zipper Dimerization and Specificity of DNA Recognition of the Melanocyte Master Regulator Mitf
pubmed doi rcsb
molecule tags Dna-binding protein/dna
source organism Mus musculus
molecule keywords MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR
total genus 19
structure length 57
sequence length 61
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 4atiA00
4ATKA 4H10B 4F3LB 5I50A 3U5VA 1NKPB 1MDYB 3MUJA 2LFHA 1NLWB 1HLOA 4H10A 4F3LA 2YPBB 2YPAB 2MH3A 1NKPA 1MDYA 5EYOA 1AN2A 1AN4A 1NLWA 4ATIA 5I4ZA 1R05A 1AM9A 2YPBA 2YPAA 2QL2B 1UKLC 4AYAA 4ATHA 1A0AA 2QL2A
chains in the Genus database with same CATH superfamily
4ATKA 4H10B 4F3LB 5I50A 3U5VA 1NKPB 1MDYB 3MUJA 1K1FA 2LFHA 1NLWB 1HLOA 1ZZAA 4H10A 4F3LA 2YPBB 2YPAB 2MH3A 1NKPA 1MDYA 5EYOA 1AN2A 1AN4A 1NLWA 4ATIA 5I4ZA 1R05A 1AM9A 2YPBA 2YPAA 2QL2B 1UKLC 4AYAA 4ATHA 1A0AA 2QL2A
chains in the Genus database with same CATH topology
4ATKA 4H10B 4F3LB 5I50A 3U5VA 1NKPB 1MDYB 3MUJA 2LFHA 1NLWB 1HLOA 4H10A 4F3LA 2YPBB 2YPAB 2MH3A 1NKPA 1MDYA 5EYOA 1AN2A 1AN4A 1NLWA 4ATIA 5I4ZA 1R05A 1AM9A 2YPBA 2YPAA 2QL2B 1UKLC 4AYAA 4ATHA 1A0AA 2QL2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ATK A;  4H10 B;  4F3L B;  5I50 A;  3U5V A;  1NKP B;  1MDY B;  3MUJ A;  2LFH A;  1NLW B;  1HLO A;  4H10 A;  4F3L A;  2YPB B;  2YPA B;  2MH3 A;  1NKP A;  1MDY A;  5EYO A;  1AN2 A;  1AN4 A;  1NLW A;  4ATI A;  5I4Z A;  1R05 A;  1AM9 A;  2YPB A;  2YPA A;  2QL2 B;  1UKL C;  4AYA A;  4ATH A;  1A0A A;  2QL2 A; 
#chains in the Genus database with same CATH topology
 4ATK A;  4H10 B;  4F3L B;  5I50 A;  3U5V A;  1NKP B;  1MDY B;  3MUJ A;  1K1F A;  2LFH A;  1NLW B;  1HLO A;  1ZZA A;  4H10 A;  4F3L A;  2YPB B;  2YPA B;  2MH3 A;  1NKP A;  1MDY A;  5EYO A;  1AN2 A;  1AN4 A;  1NLW A;  4ATI A;  5I4Z A;  1R05 A;  1AM9 A;  2YPB A;  2YPA A;  2QL2 B;  1UKL C;  4AYA A;  4ATH A;  1A0A A;  2QL2 A; 
#chains in the Genus database with same CATH homology
 4ATK A;  4H10 B;  4F3L B;  5I50 A;  3U5V A;  1NKP B;  1MDY B;  3MUJ A;  2LFH A;  1NLW B;  1HLO A;  4H10 A;  4F3L A;  2YPB B;  2YPA B;  2MH3 A;  1NKP A;  1MDY A;  5EYO A;  1AN2 A;  1AN4 A;  1NLW A;  4ATI A;  5I4Z A;  1R05 A;  1AM9 A;  2YPB A;  2YPA A;  2QL2 B;  1UKL C;  4AYA A;  4ATH A;  1A0A A;  2QL2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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