4ATIA

Mitf:m-box complex
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
61
structure length
57
Chain Sequence
HNLIERRRRFNINDRIKELGTLIPKSMRWNKGTILKASVDYIRKLQREQQRAKDLEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Restricted Leucine Zipper Dimerization and Specificity of DNA Recognition of the Melanocyte Master Regulator Mitf
pubmed doi rcsb
molecule keywords MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR
molecule tags Dna-binding protein/dna
source organism Mus musculus
total genus 19
structure length 57
sequence length 61
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 4atiA00
4F3LB 4ATHA 1A0AA 4H10A 4ATIA 2YPAB 1UKLC 1MDYA 1NKPA 1AN4A 4AYAA 2YPBB 1NLWB 1NLWA 5I4ZA 3MUJA 1HLOA 4H10B 2QL2A 1NKPB 1MDYB 1AM9A 1R05A 4F3LA 3U5VA 5EYOA 2MH3A 2QL2B 1AN2A 2YPAA 5I50A 4ATKA 2YPBA 2LFHA
chains in the Genus database with same CATH superfamily
4F3LB 4ATHA 1A0AA 4H10A 4ATIA 2YPAB 1UKLC 1MDYA 1NKPA 1AN4A 4AYAA 2YPBB 1NLWB 1NLWA 5I4ZA 3MUJA 1HLOA 4H10B 2QL2A 1NKPB 1MDYB 1ZZAA 1AM9A 1R05A 1K1FA 4F3LA 3U5VA 5EYOA 2MH3A 2QL2B 1AN2A 2YPAA 5I50A 4ATKA 2YPBA 2LFHA
chains in the Genus database with same CATH topology
4F3LB 4ATHA 1A0AA 4H10A 4ATIA 2YPAB 1UKLC 1MDYA 1NKPA 1AN4A 4AYAA 2YPBB 1NLWB 1NLWA 5I4ZA 3MUJA 1HLOA 4H10B 2QL2A 1NKPB 1MDYB 1AM9A 1R05A 4F3LA 3U5VA 5EYOA 2MH3A 2QL2B 1AN2A 2YPAA 5I50A 4ATKA 2YPBA 2LFHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F3L B;  4ATH A;  1A0A A;  4H10 A;  4ATI A;  2YPA B;  1UKL C;  1MDY A;  1NKP A;  1AN4 A;  4AYA A;  2YPB B;  1NLW B;  1NLW A;  5I4Z A;  3MUJ A;  1HLO A;  4H10 B;  2QL2 A;  1NKP B;  1MDY B;  1AM9 A;  1R05 A;  4F3L A;  3U5V A;  5EYO A;  2MH3 A;  2QL2 B;  1AN2 A;  2YPA A;  5I50 A;  4ATK A;  2YPB A;  2LFH A; 
#chains in the Genus database with same CATH topology
 4F3L B;  4ATH A;  1A0A A;  4H10 A;  4ATI A;  2YPA B;  1UKL C;  1MDY A;  1NKP A;  1AN4 A;  4AYA A;  2YPB B;  1NLW B;  1NLW A;  5I4Z A;  3MUJ A;  1HLO A;  4H10 B;  2QL2 A;  1NKP B;  1MDY B;  1ZZA A;  1AM9 A;  1R05 A;  1K1F A;  4F3L A;  3U5V A;  5EYO A;  2MH3 A;  2QL2 B;  1AN2 A;  2YPA A;  5I50 A;  4ATK A;  2YPB A;  2LFH A; 
#chains in the Genus database with same CATH homology
 4F3L B;  4ATH A;  1A0A A;  4H10 A;  4ATI A;  2YPA B;  1UKL C;  1MDY A;  1NKP A;  1AN4 A;  4AYA A;  2YPB B;  1NLW B;  1NLW A;  5I4Z A;  3MUJ A;  1HLO A;  4H10 B;  2QL2 A;  1NKP B;  1MDY B;  1AM9 A;  1R05 A;  4F3L A;  3U5V A;  5EYO A;  2MH3 A;  2QL2 B;  1AN2 A;  2YPA A;  5I50 A;  4ATK A;  2YPB A;  2LFH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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