4ATKA

Mitf:e-box complex
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
62
structure length
60
Chain Sequence
DNHNLIERRRRFNINDRIKELGTLIPKDPDMRWNKGTILKASVDYIRKLQREQQRAKDLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Restricted Leucine Zipper Dimerization and Specificity of DNA Recognition of the Melanocyte Master Regulator Mitf
pubmed doi rcsb
molecule tags Dna binding protein/dna
source organism Mus musculus
molecule keywords MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR
total genus 20
structure length 60
sequence length 62
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 4atkA00
2YPBA 5EYOA 1HLOA 1MDYA 4H10B 4F3LA 1NKPB 1NLWB 5I4ZA 1AN4A 1AN2A 2MH3A 2QL2B 2YPAB 1UKLC 3U5VA 1R05A 4H10A 1NLWA 1NKPA 1A0AA 4AYAA 3MUJA 2LFHA 1AM9A 2YPBB 5I50A 2QL2A 2YPAA 1MDYB 4F3LB 4ATIA 4ATKA 4ATHA
chains in the Genus database with same CATH superfamily
2YPBA 5EYOA 1HLOA 1MDYA 4H10B 4F3LA 1NKPB 1NLWB 5I4ZA 1K1FA 1AN4A 1AN2A 2MH3A 2QL2B 2YPAB 1UKLC 3U5VA 1R05A 4H10A 1NLWA 1NKPA 1A0AA 4AYAA 3MUJA 2LFHA 1AM9A 2YPBB 5I50A 2QL2A 2YPAA 1MDYB 4F3LB 4ATIA 1ZZAA 4ATKA 4ATHA
chains in the Genus database with same CATH topology
2YPBA 5EYOA 1HLOA 1MDYA 4H10B 4F3LA 1NKPB 1NLWB 5I4ZA 1AN4A 1AN2A 2MH3A 2QL2B 2YPAB 1UKLC 3U5VA 1R05A 4H10A 1NLWA 1NKPA 1A0AA 4AYAA 3MUJA 2LFHA 1AM9A 2YPBB 5I50A 2QL2A 2YPAA 1MDYB 4F3LB 4ATIA 4ATKA 4ATHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YPB A;  5EYO A;  1HLO A;  1MDY A;  4H10 B;  4F3L A;  1NKP B;  1NLW B;  5I4Z A;  1AN4 A;  1AN2 A;  2MH3 A;  2QL2 B;  2YPA B;  1UKL C;  3U5V A;  1R05 A;  4H10 A;  1NLW A;  1NKP A;  1A0A A;  4AYA A;  3MUJ A;  2LFH A;  1AM9 A;  2YPB B;  5I50 A;  2QL2 A;  2YPA A;  1MDY B;  4F3L B;  4ATI A;  4ATK A;  4ATH A; 
#chains in the Genus database with same CATH topology
 2YPB A;  5EYO A;  1HLO A;  1MDY A;  4H10 B;  4F3L A;  1NKP B;  1NLW B;  5I4Z A;  1K1F A;  1AN4 A;  1AN2 A;  2MH3 A;  2QL2 B;  2YPA B;  1UKL C;  3U5V A;  1R05 A;  4H10 A;  1NLW A;  1NKP A;  1A0A A;  4AYA A;  3MUJ A;  2LFH A;  1AM9 A;  2YPB B;  5I50 A;  2QL2 A;  2YPA A;  1MDY B;  4F3L B;  4ATI A;  1ZZA A;  4ATK A;  4ATH A; 
#chains in the Genus database with same CATH homology
 2YPB A;  5EYO A;  1HLO A;  1MDY A;  4H10 B;  4F3L A;  1NKP B;  1NLW B;  5I4Z A;  1AN4 A;  1AN2 A;  2MH3 A;  2QL2 B;  2YPA B;  1UKL C;  3U5V A;  1R05 A;  4H10 A;  1NLW A;  1NKP A;  1A0A A;  4AYA A;  3MUJ A;  2LFH A;  1AM9 A;  2YPB B;  5I50 A;  2QL2 A;  2YPA A;  1MDY B;  4F3L B;  4ATI A;  4ATK A;  4ATH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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