4ATKA

Mitf:e-box complex
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
62
structure length
60
Chain Sequence
DNHNLIERRRRFNINDRIKELGTLIPKDPDMRWNKGTILKASVDYIRKLQREQQRAKDLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Restricted Leucine Zipper Dimerization and Specificity of DNA Recognition of the Melanocyte Master Regulator Mitf
pubmed doi rcsb
molecule keywords MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR
molecule tags Dna binding protein/dna
source organism Mus musculus
total genus 20
structure length 60
sequence length 62
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 4atkA00
5EYOA 2YPAB 3U5VA 4AYAA 2QL2A 1R05A 4F3LA 4H10B 2YPBB 5I50A 1A0AA 1NLWA 1NKPA 1AN4A 2MH3A 4ATKA 1MDYA 3MUJA 2YPAA 4F3LB 2QL2B 4H10A 1AN2A 4ATIA 2YPBA 1HLOA 1NLWB 1NKPB 1AM9A 5I4ZA 2LFHA 1MDYB 4ATHA 1UKLC
chains in the Genus database with same CATH superfamily
5EYOA 2YPAB 3U5VA 4AYAA 2QL2A 1R05A 4F3LA 4H10B 2YPBB 5I50A 1A0AA 1NLWA 1K1FA 1NKPA 1AN4A 2MH3A 4ATKA 1MDYA 3MUJA 2YPAA 4F3LB 2QL2B 4H10A 1AN2A 4ATIA 2YPBA 1HLOA 1NLWB 1NKPB 1AM9A 5I4ZA 2LFHA 1MDYB 4ATHA 1UKLC 1ZZAA
chains in the Genus database with same CATH topology
5EYOA 2YPAB 3U5VA 4AYAA 2QL2A 1R05A 4F3LA 4H10B 2YPBB 5I50A 1A0AA 1NLWA 1NKPA 1AN4A 2MH3A 4ATKA 1MDYA 3MUJA 2YPAA 4F3LB 2QL2B 4H10A 1AN2A 4ATIA 2YPBA 1HLOA 1NLWB 1NKPB 1AM9A 5I4ZA 2LFHA 1MDYB 4ATHA 1UKLC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EYO A;  2YPA B;  3U5V A;  4AYA A;  2QL2 A;  1R05 A;  4F3L A;  4H10 B;  2YPB B;  5I50 A;  1A0A A;  1NLW A;  1NKP A;  1AN4 A;  2MH3 A;  4ATK A;  1MDY A;  3MUJ A;  2YPA A;  4F3L B;  2QL2 B;  4H10 A;  1AN2 A;  4ATI A;  2YPB A;  1HLO A;  1NLW B;  1NKP B;  1AM9 A;  5I4Z A;  2LFH A;  1MDY B;  4ATH A;  1UKL C; 
#chains in the Genus database with same CATH topology
 5EYO A;  2YPA B;  3U5V A;  4AYA A;  2QL2 A;  1R05 A;  4F3L A;  4H10 B;  2YPB B;  5I50 A;  1A0A A;  1NLW A;  1K1F A;  1NKP A;  1AN4 A;  2MH3 A;  4ATK A;  1MDY A;  3MUJ A;  2YPA A;  4F3L B;  2QL2 B;  4H10 A;  1AN2 A;  4ATI A;  2YPB A;  1HLO A;  1NLW B;  1NKP B;  1AM9 A;  5I4Z A;  2LFH A;  1MDY B;  4ATH A;  1UKL C;  1ZZA A; 
#chains in the Genus database with same CATH homology
 5EYO A;  2YPA B;  3U5V A;  4AYA A;  2QL2 A;  1R05 A;  4F3L A;  4H10 B;  2YPB B;  5I50 A;  1A0A A;  1NLW A;  1NKP A;  1AN4 A;  2MH3 A;  4ATK A;  1MDY A;  3MUJ A;  2YPA A;  4F3L B;  2QL2 B;  4H10 A;  1AN2 A;  4ATI A;  2YPB A;  1HLO A;  1NLW B;  1NKP B;  1AM9 A;  5I4Z A;  2LFH A;  1MDY B;  4ATH A;  1UKL C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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