4EL6A

Crystal structure of ipse/alpha-1 from schistosoma mansoni eggs
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
102
structure length
97
Chain Sequence
CKYCLQLYDETYERGSYIEVYKSVGSLSPPWTPGSVCVPFVERPYWYLFDNVNYTGRITGLGHGTCIDDFTKSGFKGISSIKRCIQTKDGKVECINQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and functional analysis of IPSE/alpha-1, an IL-4-inducing factor secreted from Schistosoma mansoni eggs, reveals an IgE-binding crystallin fold
rcsb
molecule tags Signaling protein
source organism Schistosoma mansoni
molecule keywords IL-4-inducing protein
total genus 17
structure length 97
sequence length 102
ec nomenclature
pdb deposition date 2012-04-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18258 IL4_i_Ig Interleukin-4 inducing immunoglobulin-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.20.10 Mainly Beta Sandwich Gamma-B Crystallin; domain 1 Crystallins 4el6A00
3SO1A 2A5MA 1BLBA 1BD7A 4PSPA 1ZIRA 2M3CA 1DSLA 4W9AA 1NPSA 1YTQA 2K1XA 2KFBA 3SO0A 4EL6A 2KP5A 4GCRA 3SNYA 2BB2A 2B1OA 3ENUA 1E7NA 1AG4A 1HK0X 2DADA 1ZWMA 1GAMA 2BV2A 3HZBA 3IAJA 3CW3A 1PRRA 5HT9A 1OKIA 1PRSA 1HDFA 1YHPA 2JDFA 1A45A 1A7HA 1M8UA 3HZ2A 1ZWOA 3I9HA 4W9BA 1ELPA 1AMMA 1ZIQA 1ZIEA 1H4AX 2NBRA 3ENTA 2V2UA 1HA4A 1ZGTA 2JDGA 3LWKA 3QK3A 4NI3A 3SNZA 5HT8A 4GR7A 2K1WA 4PSRA 4FD9A 4AKAA 2M3UA 4JGFA 1I5IA 1GCSA 2G98A 4IAUA 1A5DA 2M3TA
chains in the Genus database with same CATH superfamily
3SO1A 1BLBA 1NPSA 1YTQA 2K1XA 1G6EA 3SNYA 1ZWMA 1GAMA 3I9HA 1M8UA 1GH5A 1HA4A 3QK3A 4FD9A 2M3UA 1GCSA 1C01A 1A5DA 2M3TA 1DSLA 4W9AA 2KP5A 4GCRA 2BB2A 1WKTA 1HK0X 3IAJA 3HZBA 1PRRA 5HT9A 1YHPA 1A7HA 3HZ2A 1AMMA 4W9BA 1ZIEA 3ENTA 2V2UA 2JDGA 3LWKA 4GR7A 4PSRA 1I5IA 4AKAA 1BD7A 1ZIRA 2KFBA 3SO0A 3ENUA 1PRSA 1ZWOA 2NBRA 1ZGTA 4NI3A 5HT8A 3SNZA 2K1WA 2G98A 2A5MA 4PSPA 2M3CA 1F53A 4EL6A 3UJZA 2B1OA 1E7NA 1AG4A 2DADA 2BV2A 3CW3A 1OKIA 1HDFA 1BHUA 2JDFA 1A45A 1ELPA 1ZIQA 1H4AX 4JGFA 4IAUA
chains in the Genus database with same CATH topology
3SO1A 2A5MA 1BLBA 1BD7A 4PSPA 1ZIRA 2M3CA 1DSLA 4W9AA 1NPSA 1YTQA 2K1XA 2KFBA 3SO0A 4EL6A 2KP5A 4GCRA 3SNYA 2BB2A 2B1OA 3ENUA 1E7NA 1AG4A 1HK0X 2DADA 1ZWMA 1GAMA 2BV2A 3HZBA 3IAJA 3CW3A 1PRRA 5HT9A 1OKIA 1PRSA 1HDFA 1YHPA 2JDFA 1A45A 1A7HA 1M8UA 3HZ2A 1ZWOA 3I9HA 4W9BA 1ELPA 1AMMA 1ZIQA 1ZIEA 1H4AX 2NBRA 3ENTA 2V2UA 1HA4A 1ZGTA 2JDGA 3LWKA 3QK3A 4NI3A 3SNZA 5HT8A 4GR7A 2K1WA 4PSRA 4FD9A 4AKAA 2M3UA 4JGFA 1I5IA 1GCSA 2G98A 4IAUA 1A5DA 2M3TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SO1 A;  2A5M A;  1BLB A;  1BD7 A;  4PSP A;  1ZIR A;  2M3C A;  1DSL A;  4W9A A;  1NPS A;  1YTQ A;  2K1X A;  2KFB A;  3SO0 A;  4EL6 A;  2KP5 A;  4GCR A;  3SNY A;  2BB2 A;  2B1O A;  3ENU A;  1E7N A;  1AG4 A;  1HK0 X;  2DAD A;  1ZWM A;  1GAM A;  2BV2 A;  3HZB A;  3IAJ A;  3CW3 A;  1PRR A;  5HT9 A;  1OKI A;  1PRS A;  1HDF A;  1YHP A;  2JDF A;  1A45 A;  1A7H A;  1M8U A;  3HZ2 A;  1ZWO A;  3I9H A;  4W9B A;  1ELP A;  1AMM A;  1ZIQ A;  1ZIE A;  1H4A X;  2NBR A;  3ENT A;  2V2U A;  1HA4 A;  1ZGT A;  2JDG A;  3LWK A;  3QK3 A;  4NI3 A;  3SNZ A;  5HT8 A;  4GR7 A;  2K1W A;  4PSR A;  4FD9 A;  4AKA A;  2M3U A;  4JGF A;  1I5I A;  1GCS A;  2G98 A;  4IAU A;  1A5D A;  2M3T A; 
#chains in the Genus database with same CATH topology
 3SO1 A;  1BLB A;  1NPS A;  1YTQ A;  2K1X A;  1G6E A;  3SNY A;  1ZWM A;  1GAM A;  3I9H A;  1M8U A;  1GH5 A;  1HA4 A;  3QK3 A;  4FD9 A;  2M3U A;  1GCS A;  1C01 A;  1A5D A;  2M3T A;  1DSL A;  4W9A A;  2KP5 A;  4GCR A;  2BB2 A;  1WKT A;  1HK0 X;  3IAJ A;  3HZB A;  1PRR A;  5HT9 A;  1YHP A;  1A7H A;  3HZ2 A;  1AMM A;  4W9B A;  1ZIE A;  3ENT A;  2V2U A;  2JDG A;  3LWK A;  4GR7 A;  4PSR A;  1I5I A;  4AKA A;  1BD7 A;  1ZIR A;  2KFB A;  3SO0 A;  3ENU A;  1PRS A;  1ZWO A;  2NBR A;  1ZGT A;  4NI3 A;  5HT8 A;  3SNZ A;  2K1W A;  2G98 A;  2A5M A;  4PSP A;  2M3C A;  1F53 A;  4EL6 A;  3UJZ A;  2B1O A;  1E7N A;  1AG4 A;  2DAD A;  2BV2 A;  3CW3 A;  1OKI A;  1HDF A;  1BHU A;  2JDF A;  1A45 A;  1ELP A;  1ZIQ A;  1H4A X;  4JGF A;  4IAU A; 
#chains in the Genus database with same CATH homology
 3SO1 A;  2A5M A;  1BLB A;  1BD7 A;  4PSP A;  1ZIR A;  2M3C A;  1DSL A;  4W9A A;  1NPS A;  1YTQ A;  2K1X A;  2KFB A;  3SO0 A;  4EL6 A;  2KP5 A;  4GCR A;  3SNY A;  2BB2 A;  2B1O A;  3ENU A;  1E7N A;  1AG4 A;  1HK0 X;  2DAD A;  1ZWM A;  1GAM A;  2BV2 A;  3HZB A;  3IAJ A;  3CW3 A;  1PRR A;  5HT9 A;  1OKI A;  1PRS A;  1HDF A;  1YHP A;  2JDF A;  1A45 A;  1A7H A;  1M8U A;  3HZ2 A;  1ZWO A;  3I9H A;  4W9B A;  1ELP A;  1AMM A;  1ZIQ A;  1ZIE A;  1H4A X;  2NBR A;  3ENT A;  2V2U A;  1HA4 A;  1ZGT A;  2JDG A;  3LWK A;  3QK3 A;  4NI3 A;  3SNZ A;  5HT8 A;  4GR7 A;  2K1W A;  4PSR A;  4FD9 A;  4AKA A;  2M3U A;  4JGF A;  1I5I A;  1GCS A;  2G98 A;  4IAU A;  1A5D A;  2M3T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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