4GX7A

Vibrio cholerae cytolysin beta-prism domain with methyl-alpha-mannose bound
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
132
structure length
132
Chain Sequence
MSSPILGYTQGKMNQQRVGQDNRLYVRAGAAIDALGSASDLLVGGNGGSLSSVDLSGVKSITATSGDFQYGGQQLVALTFTYQDGRQQTVGSKAYVTNAHEDRFDLPDAAKITQLKIWADDWLVKGVQFDLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Vibrio cholerae Cytolysin Recognizes the Heptasaccharide Core of Complex N-Glycans with Nanomolar Affinity.
pubmed doi rcsb
molecule tags Toxin
source organism Vibrio cholerae
molecule keywords Cytolysin and hemolysin HlyA Pore-forming toxin
total genus 27
structure length 132
sequence length 132
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2012-09-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16458 Beta-prism_lec Beta-prism lectin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.100.10.30 Mainly Beta Aligned Prism Vitelline Membrane Outer Layer Protein I, subunit A Jacalin-like lectin domain 4gx7A00
4MQ0A 1KUJA 3R50A 1KU8A 1J4UA 3O44A 1UGWC 3LL0A 1PXDA 4R6QA 4WOGA 4AKBA 3APAA 4R6NA 4PIFA 1TOQA 4R6OA 1UGXA 2GUEA 1OUWA 4AKDA 1J4SA 3LL1A 4PIKA 1ZGSA 3R51A 5J51A 2BN0A 3MITA 1C3MA 3LLYA 5BN6E 4R6PA 2GUXA 1UH0A 3P8SA 3MIVA 1C3KA 1UGYA 1WS5A 2BMYA 5J4TA 2GUCA 5J50A 4PITA 2GUDA 2NU5A 3LKYA 4R6RA 4AK4A 3WOBA 1JOTA 3AQGA 3MIUA 5JM1A 1UGYC 2GTYA 1WS4A 1WS5C 3R52A 5J4XA 2HYQA 3LL2A 3VZFA 4GX7A 1ZGRA 1C3NA 1XEZA 1WS4C 3VZEA 3VY7A 5AV7A 4PIUA 1JACA 1VBOA 2BMZA 1XXRA 5EXGA 1UH1A 1XXQA 2JZ4A 1X1VA 3VZGA 3VY6A 3WOCA 1J4TA 1M26A 1UGWA 3LLZA 4AKCA 1TP8A 1VBPA 2NUOA 4DDNA 3LM1A 2HYRA
chains in the Genus database with same CATH superfamily
4MQ0A 1KUJA 3R50A 1KU8A 1J4UA 3O44A 1UGWC 1VMOA 3LL0A 3TOWA 1PXDA 4R6QA 4WOGA 4AKBA 3APAA 1W99A 1DLCA 3EB7A 4R6NA 4PIFA 1TOQA 4R6OA 1UGXA 2GUEA 1OUWA 4AKDA 1J4SA 3LL1A 4PIKA 1ZGSA 3R51A 5J51A 4D8MA 2QP2A 2BN0A 3MITA 1C3MA 3LLYA 4QX1A 5BN6E 4R6PA 2GUXA 1UH0A 3P8SA 3MIVA 1C3KA 1UGYA 1WS5A 2BMYA 5J4TA 1JI6A 2GUCA 5J50A 2C9KA 4PITA 2GUDA 2NU5A 4QX3A 3LKYA 4R6RA 4AK4A 3WOBA 1JOTA 3AQGA 3MIUA 5JM1A 1UGYC 1CIYA 2GTYA 1WS4A 1WS5C 3R52A 5J4XA 2HYQA 3LL2A 4MOAA 3VZFA 4GX7A 1ZGRA 1C3NA 1XEZA 1WS4C 3VZEA 3VY7A 4QX2A 5AV7A 1I5PA 4PIUA 1JACA 4ARXA 1VBOA 2BMZA 1XXRA 5EXGA 1UH1A 1XXQA 2JZ4A 1X1VA 3VZGA 3VY6A 3WOCA 1J4TA 4ARYA 1M26A 4W8JA 1UGWA 3LLZA 4AKCA 1TP8A 1VBPA 2NUOA 4DDNA 3LM1A 2HYRA 4QX0A
chains in the Genus database with same CATH topology
4MQ0A 1KUJA 3R50A 1KU8A 1J4UA 3O44A 1UGWC 3LL0A 1PXDA 4R6QA 4WOGA 4AKBA 3APAA 4R6NA 4PIFA 1TOQA 4R6OA 1UGXA 2GUEA 1OUWA 4AKDA 1J4SA 3LL1A 4PIKA 1ZGSA 3R51A 5J51A 2BN0A 3MITA 1C3MA 3LLYA 5BN6E 4R6PA 2GUXA 1UH0A 3P8SA 3MIVA 1C3KA 1UGYA 1WS5A 2BMYA 5J4TA 2GUCA 5J50A 4PITA 2GUDA 2NU5A 3LKYA 4R6RA 4AK4A 3WOBA 1JOTA 3AQGA 3MIUA 5JM1A 1UGYC 2GTYA 1WS4A 1WS5C 3R52A 5J4XA 2HYQA 3LL2A 3VZFA 4GX7A 1ZGRA 1C3NA 1XEZA 1WS4C 3VZEA 3VY7A 5AV7A 4PIUA 1JACA 1VBOA 2BMZA 1XXRA 5EXGA 1UH1A 1XXQA 2JZ4A 1X1VA 3VZGA 3VY6A 3WOCA 1J4TA 1M26A 1UGWA 3LLZA 4AKCA 1TP8A 1VBPA 2NUOA 4DDNA 3LM1A 2HYRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MQ0 A;  1KUJ A;  3R50 A;  1KU8 A;  1J4U A;  3O44 A;  1UGW C;  3LL0 A;  1PXD A;  4R6Q A;  4WOG A;  4AKB A;  3APA A;  4R6N A;  4PIF A;  1TOQ A;  4R6O A;  1UGX A;  2GUE A;  1OUW A;  4AKD A;  1J4S A;  3LL1 A;  4PIK A;  1ZGS A;  3R51 A;  5J51 A;  2BN0 A;  3MIT A;  1C3M A;  3LLY A;  5BN6 E;  4R6P A;  2GUX A;  1UH0 A;  3P8S A;  3MIV A;  1C3K A;  1UGY A;  1WS5 A;  2BMY A;  5J4T A;  2GUC A;  5J50 A;  4PIT A;  2GUD A;  2NU5 A;  3LKY A;  4R6R A;  4AK4 A;  3WOB A;  1JOT A;  3AQG A;  3MIU A;  5JM1 A;  1UGY C;  2GTY A;  1WS4 A;  1WS5 C;  3R52 A;  5J4X A;  2HYQ A;  3LL2 A;  3VZF A;  4GX7 A;  1ZGR A;  1C3N A;  1XEZ A;  1WS4 C;  3VZE A;  3VY7 A;  5AV7 A;  4PIU A;  1JAC A;  1VBO A;  2BMZ A;  1XXR A;  5EXG A;  1UH1 A;  1XXQ A;  2JZ4 A;  1X1V A;  3VZG A;  3VY6 A;  3WOC A;  1J4T A;  1M26 A;  1UGW A;  3LLZ A;  4AKC A;  1TP8 A;  1VBP A;  2NUO A;  4DDN A;  3LM1 A;  2HYR A; 
#chains in the Genus database with same CATH topology
 4MQ0 A;  1KUJ A;  3R50 A;  1KU8 A;  1J4U A;  3O44 A;  1UGW C;  1VMO A;  3LL0 A;  3TOW A;  1PXD A;  4R6Q A;  4WOG A;  4AKB A;  3APA A;  1W99 A;  1DLC A;  3EB7 A;  4R6N A;  4PIF A;  1TOQ A;  4R6O A;  1UGX A;  2GUE A;  1OUW A;  4AKD A;  1J4S A;  3LL1 A;  4PIK A;  1ZGS A;  3R51 A;  5J51 A;  4D8M A;  2QP2 A;  2BN0 A;  3MIT A;  1C3M A;  3LLY A;  4QX1 A;  5BN6 E;  4R6P A;  2GUX A;  1UH0 A;  3P8S A;  3MIV A;  1C3K A;  1UGY A;  1WS5 A;  2BMY A;  5J4T A;  1JI6 A;  2GUC A;  5J50 A;  2C9K A;  4PIT A;  2GUD A;  2NU5 A;  4QX3 A;  3LKY A;  4R6R A;  4AK4 A;  3WOB A;  1JOT A;  3AQG A;  3MIU A;  5JM1 A;  1UGY C;  1CIY A;  2GTY A;  1WS4 A;  1WS5 C;  3R52 A;  5J4X A;  2HYQ A;  3LL2 A;  4MOA A;  3VZF A;  4GX7 A;  1ZGR A;  1C3N A;  1XEZ A;  1WS4 C;  3VZE A;  3VY7 A;  4QX2 A;  5AV7 A;  1I5P A;  4PIU A;  1JAC A;  4ARX A;  1VBO A;  2BMZ A;  1XXR A;  5EXG A;  1UH1 A;  1XXQ A;  2JZ4 A;  1X1V A;  3VZG A;  3VY6 A;  3WOC A;  1J4T A;  4ARY A;  1M26 A;  4W8J A;  1UGW A;  3LLZ A;  4AKC A;  1TP8 A;  1VBP A;  2NUO A;  4DDN A;  3LM1 A;  2HYR A;  4QX0 A; 
#chains in the Genus database with same CATH homology
 4MQ0 A;  1KUJ A;  3R50 A;  1KU8 A;  1J4U A;  3O44 A;  1UGW C;  3LL0 A;  1PXD A;  4R6Q A;  4WOG A;  4AKB A;  3APA A;  4R6N A;  4PIF A;  1TOQ A;  4R6O A;  1UGX A;  2GUE A;  1OUW A;  4AKD A;  1J4S A;  3LL1 A;  4PIK A;  1ZGS A;  3R51 A;  5J51 A;  2BN0 A;  3MIT A;  1C3M A;  3LLY A;  5BN6 E;  4R6P A;  2GUX A;  1UH0 A;  3P8S A;  3MIV A;  1C3K A;  1UGY A;  1WS5 A;  2BMY A;  5J4T A;  2GUC A;  5J50 A;  4PIT A;  2GUD A;  2NU5 A;  3LKY A;  4R6R A;  4AK4 A;  3WOB A;  1JOT A;  3AQG A;  3MIU A;  5JM1 A;  1UGY C;  2GTY A;  1WS4 A;  1WS5 C;  3R52 A;  5J4X A;  2HYQ A;  3LL2 A;  3VZF A;  4GX7 A;  1ZGR A;  1C3N A;  1XEZ A;  1WS4 C;  3VZE A;  3VY7 A;  5AV7 A;  4PIU A;  1JAC A;  1VBO A;  2BMZ A;  1XXR A;  5EXG A;  1UH1 A;  1XXQ A;  2JZ4 A;  1X1V A;  3VZG A;  3VY6 A;  3WOC A;  1J4T A;  1M26 A;  1UGW A;  3LLZ A;  4AKC A;  1TP8 A;  1VBP A;  2NUO A;  4DDN A;  3LM1 A;  2HYR A; 
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similar chains in the Genus database (?% sequence similarity)
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