4GX7A

Vibrio cholerae cytolysin beta-prism domain with methyl-alpha-mannose bound
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
132
structure length
132
Chain Sequence
MSSPILGYTQGKMNQQRVGQDNRLYVRAGAAIDALGSASDLLVGGNGGSLSSVDLSGVKSITATSGDFQYGGQQLVALTFTYQDGRQQTVGSKAYVTNAHEDRFDLPDAAKITQLKIWADDWLVKGVQFDLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Vibrio cholerae Cytolysin Recognizes the Heptasaccharide Core of Complex N-Glycans with Nanomolar Affinity.
pubmed doi rcsb
molecule tags Toxin
source organism Vibrio cholerae
molecule keywords Cytolysin and hemolysin HlyA Pore-forming toxin
total genus 27
structure length 132
sequence length 132
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2012-09-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16458 Beta-prism_lec Beta-prism lectin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.100.10.30 Mainly Beta Aligned Prism Vitelline Membrane Outer Layer Protein I, subunit A Jacalin-like lectin domain 4gx7A00
5J4TA 3R51A 1UGWA 1XEZA 2GUEA 2NUOA 5J4XA 1OUWA 3R52A 1KU8A 4DDNA 1PXDA 4GX7A 2JZ4A 3AQGA 5EXGA 2BN0A 1WS4C 5AV7A 4AKBA 1ZGSA 1KUJA 4PIKA 1C3MA 3MIUA 4R6OA 2GUCA 3O44A 1WS4A 1J4TA 3LM1A 3VZFA 1JACA 3R50A 4R6QA 3LL1A 4PIUA 3LL2A 1TP8A 3MIVA 5BN6E 2BMYA 1J4UA 3APAA 4R6RA 4AKCA 3LKYA 3LLYA 2GUDA 5JM1A 4PITA 1J4SA 1C3NA 4AKDA 1JOTA 1UGYC 3P8SA 2GTYA 5J51A 1ZGRA 2HYRA 3VZGA 3LLZA 3WOCA 1UH1A 1VBOA 1C3KA 1UGYA 4AK4A 1UGWC 4R6PA 2NU5A 1VBPA 1XXQA 2GUXA 1WS5C 4PIFA 2HYQA 3VY7A 4WOGA 3VY6A 4MQ0A 2BMZA 5J50A 1M26A 1WS5A 3WOBA 1XXRA 1UH0A 1X1VA 1UGXA 3MITA 3VZEA 3LL0A 4R6NA 1TOQA
chains in the Genus database with same CATH superfamily
1CIYA 5J4TA 3EB7A 3R51A 4ARYA 1UGWA 1XEZA 2GUEA 2NUOA 5J4XA 1OUWA 3R52A 4QX1A 1KU8A 4QX2A 3TOWA 1PXDA 4DDNA 4GX7A 1VMOA 2JZ4A 3AQGA 5EXGA 4W8JA 2BN0A 1WS4C 5AV7A 4AKBA 1ZGSA 1KUJA 4PIKA 1C3MA 3MIUA 4R6OA 2QP2A 2GUCA 3O44A 1WS4A 1W99A 1J4TA 2C9KA 3LM1A 3VZFA 1JACA 3R50A 4R6QA 4MOAA 3LL1A 4PIUA 3LL2A 1TP8A 3MIVA 5BN6E 2BMYA 1J4UA 3APAA 4R6RA 4AKCA 3LKYA 1DLCA 4QX0A 3LLYA 2GUDA 5JM1A 4PITA 1J4SA 1C3NA 4AKDA 1JOTA 1UGYC 3P8SA 2GTYA 4QX3A 5J51A 1ZGRA 2HYRA 3VZGA 3LLZA 3WOCA 1UH1A 1VBOA 1C3KA 1UGYA 4AK4A 1UGWC 4R6PA 2NU5A 1VBPA 1XXQA 1JI6A 2GUXA 1I5PA 1WS5C 4PIFA 2HYQA 3VY7A 4WOGA 3VY6A 4MQ0A 2BMZA 4D8MA 5J50A 1M26A 1WS5A 4ARXA 3WOBA 1XXRA 1UH0A 1X1VA 1UGXA 3MITA 3VZEA 3LL0A 4R6NA 1TOQA
chains in the Genus database with same CATH topology
5J4TA 3R51A 1UGWA 1XEZA 2GUEA 2NUOA 5J4XA 1OUWA 3R52A 1KU8A 4DDNA 1PXDA 4GX7A 2JZ4A 3AQGA 5EXGA 2BN0A 1WS4C 5AV7A 4AKBA 1ZGSA 1KUJA 4PIKA 1C3MA 3MIUA 4R6OA 2GUCA 3O44A 1WS4A 1J4TA 3LM1A 3VZFA 1JACA 3R50A 4R6QA 3LL1A 4PIUA 3LL2A 1TP8A 3MIVA 5BN6E 2BMYA 1J4UA 3APAA 4R6RA 4AKCA 3LKYA 3LLYA 2GUDA 5JM1A 4PITA 1J4SA 1C3NA 4AKDA 1JOTA 1UGYC 3P8SA 2GTYA 5J51A 1ZGRA 2HYRA 3VZGA 3LLZA 3WOCA 1UH1A 1VBOA 1C3KA 1UGYA 4AK4A 1UGWC 4R6PA 2NU5A 1VBPA 1XXQA 2GUXA 1WS5C 4PIFA 2HYQA 3VY7A 4WOGA 3VY6A 4MQ0A 2BMZA 5J50A 1M26A 1WS5A 3WOBA 1XXRA 1UH0A 1X1VA 1UGXA 3MITA 3VZEA 3LL0A 4R6NA 1TOQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5J4T A;  3R51 A;  1UGW A;  1XEZ A;  2GUE A;  2NUO A;  5J4X A;  1OUW A;  3R52 A;  1KU8 A;  4DDN A;  1PXD A;  4GX7 A;  2JZ4 A;  3AQG A;  5EXG A;  2BN0 A;  1WS4 C;  5AV7 A;  4AKB A;  1ZGS A;  1KUJ A;  4PIK A;  1C3M A;  3MIU A;  4R6O A;  2GUC A;  3O44 A;  1WS4 A;  1J4T A;  3LM1 A;  3VZF A;  1JAC A;  3R50 A;  4R6Q A;  3LL1 A;  4PIU A;  3LL2 A;  1TP8 A;  3MIV A;  5BN6 E;  2BMY A;  1J4U A;  3APA A;  4R6R A;  4AKC A;  3LKY A;  3LLY A;  2GUD A;  5JM1 A;  4PIT A;  1J4S A;  1C3N A;  4AKD A;  1JOT A;  1UGY C;  3P8S A;  2GTY A;  5J51 A;  1ZGR A;  2HYR A;  3VZG A;  3LLZ A;  3WOC A;  1UH1 A;  1VBO A;  1C3K A;  1UGY A;  4AK4 A;  1UGW C;  4R6P A;  2NU5 A;  1VBP A;  1XXQ A;  2GUX A;  1WS5 C;  4PIF A;  2HYQ A;  3VY7 A;  4WOG A;  3VY6 A;  4MQ0 A;  2BMZ A;  5J50 A;  1M26 A;  1WS5 A;  3WOB A;  1XXR A;  1UH0 A;  1X1V A;  1UGX A;  3MIT A;  3VZE A;  3LL0 A;  4R6N A;  1TOQ A; 
#chains in the Genus database with same CATH topology
 1CIY A;  5J4T A;  3EB7 A;  3R51 A;  4ARY A;  1UGW A;  1XEZ A;  2GUE A;  2NUO A;  5J4X A;  1OUW A;  3R52 A;  4QX1 A;  1KU8 A;  4QX2 A;  3TOW A;  1PXD A;  4DDN A;  4GX7 A;  1VMO A;  2JZ4 A;  3AQG A;  5EXG A;  4W8J A;  2BN0 A;  1WS4 C;  5AV7 A;  4AKB A;  1ZGS A;  1KUJ A;  4PIK A;  1C3M A;  3MIU A;  4R6O A;  2QP2 A;  2GUC A;  3O44 A;  1WS4 A;  1W99 A;  1J4T A;  2C9K A;  3LM1 A;  3VZF A;  1JAC A;  3R50 A;  4R6Q A;  4MOA A;  3LL1 A;  4PIU A;  3LL2 A;  1TP8 A;  3MIV A;  5BN6 E;  2BMY A;  1J4U A;  3APA A;  4R6R A;  4AKC A;  3LKY A;  1DLC A;  4QX0 A;  3LLY A;  2GUD A;  5JM1 A;  4PIT A;  1J4S A;  1C3N A;  4AKD A;  1JOT A;  1UGY C;  3P8S A;  2GTY A;  4QX3 A;  5J51 A;  1ZGR A;  2HYR A;  3VZG A;  3LLZ A;  3WOC A;  1UH1 A;  1VBO A;  1C3K A;  1UGY A;  4AK4 A;  1UGW C;  4R6P A;  2NU5 A;  1VBP A;  1XXQ A;  1JI6 A;  2GUX A;  1I5P A;  1WS5 C;  4PIF A;  2HYQ A;  3VY7 A;  4WOG A;  3VY6 A;  4MQ0 A;  2BMZ A;  4D8M A;  5J50 A;  1M26 A;  1WS5 A;  4ARX A;  3WOB A;  1XXR A;  1UH0 A;  1X1V A;  1UGX A;  3MIT A;  3VZE A;  3LL0 A;  4R6N A;  1TOQ A; 
#chains in the Genus database with same CATH homology
 5J4T A;  3R51 A;  1UGW A;  1XEZ A;  2GUE A;  2NUO A;  5J4X A;  1OUW A;  3R52 A;  1KU8 A;  4DDN A;  1PXD A;  4GX7 A;  2JZ4 A;  3AQG A;  5EXG A;  2BN0 A;  1WS4 C;  5AV7 A;  4AKB A;  1ZGS A;  1KUJ A;  4PIK A;  1C3M A;  3MIU A;  4R6O A;  2GUC A;  3O44 A;  1WS4 A;  1J4T A;  3LM1 A;  3VZF A;  1JAC A;  3R50 A;  4R6Q A;  3LL1 A;  4PIU A;  3LL2 A;  1TP8 A;  3MIV A;  5BN6 E;  2BMY A;  1J4U A;  3APA A;  4R6R A;  4AKC A;  3LKY A;  3LLY A;  2GUD A;  5JM1 A;  4PIT A;  1J4S A;  1C3N A;  4AKD A;  1JOT A;  1UGY C;  3P8S A;  2GTY A;  5J51 A;  1ZGR A;  2HYR A;  3VZG A;  3LLZ A;  3WOC A;  1UH1 A;  1VBO A;  1C3K A;  1UGY A;  4AK4 A;  1UGW C;  4R6P A;  2NU5 A;  1VBP A;  1XXQ A;  2GUX A;  1WS5 C;  4PIF A;  2HYQ A;  3VY7 A;  4WOG A;  3VY6 A;  4MQ0 A;  2BMZ A;  5J50 A;  1M26 A;  1WS5 A;  3WOB A;  1XXR A;  1UH0 A;  1X1V A;  1UGX A;  3MIT A;  3VZE A;  3LL0 A;  4R6N A;  1TOQ A; 
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similar chains in the Genus database (?% sequence similarity)
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