4H10A

Intermolecular recognition revealed by the complex structure of human clock-bmal1 basic helix-loop-helix domains with e-box dna
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
60
structure length
60
Chain Sequence
RIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic helix-loop-helix domains with E-box DNA.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords Aryl hydrocarbon receptor nuclear translocator-like protein
total genus 22
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 2012-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 4h10A00
1NLWB 1AM9A 4ATHA 2QL2B 5I50A 3U5VA 1MDYB 4H10A 2YPBB 5EYOA 2LFHA 4ATIA 1A0AA 3MUJA 2YPAA 4F3LA 1NKPA 1UKLC 1AN2A 1AN4A 1HLOA 4ATKA 4H10B 2MH3A 1NLWA 2QL2A 1NKPB 1R05A 4F3LB 5I4ZA 2YPAB 1MDYA 2YPBA 4AYAA
chains in the Genus database with same CATH superfamily
1NLWB 1AM9A 4ATHA 2QL2B 1ZZAA 3U5VA 5I50A 1MDYB 4H10A 2YPBB 5EYOA 2LFHA 4ATIA 1A0AA 3MUJA 2YPAA 4F3LA 1NKPA 1UKLC 1AN2A 1AN4A 1HLOA 1K1FA 4ATKA 4H10B 2MH3A 1NLWA 2QL2A 1NKPB 1R05A 4F3LB 5I4ZA 2YPAB 1MDYA 2YPBA 4AYAA
chains in the Genus database with same CATH topology
1NLWB 1AM9A 4ATHA 2QL2B 5I50A 3U5VA 1MDYB 4H10A 2YPBB 5EYOA 2LFHA 4ATIA 1A0AA 3MUJA 2YPAA 4F3LA 1NKPA 1UKLC 1AN2A 1AN4A 1HLOA 4ATKA 4H10B 2MH3A 1NLWA 2QL2A 1NKPB 1R05A 4F3LB 5I4ZA 2YPAB 1MDYA 2YPBA 4AYAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NLW B;  1AM9 A;  4ATH A;  2QL2 B;  5I50 A;  3U5V A;  1MDY B;  4H10 A;  2YPB B;  5EYO A;  2LFH A;  4ATI A;  1A0A A;  3MUJ A;  2YPA A;  4F3L A;  1NKP A;  1UKL C;  1AN2 A;  1AN4 A;  1HLO A;  4ATK A;  4H10 B;  2MH3 A;  1NLW A;  2QL2 A;  1NKP B;  1R05 A;  4F3L B;  5I4Z A;  2YPA B;  1MDY A;  2YPB A;  4AYA A; 
#chains in the Genus database with same CATH topology
 1NLW B;  1AM9 A;  4ATH A;  2QL2 B;  1ZZA A;  3U5V A;  5I50 A;  1MDY B;  4H10 A;  2YPB B;  5EYO A;  2LFH A;  4ATI A;  1A0A A;  3MUJ A;  2YPA A;  4F3L A;  1NKP A;  1UKL C;  1AN2 A;  1AN4 A;  1HLO A;  1K1F A;  4ATK A;  4H10 B;  2MH3 A;  1NLW A;  2QL2 A;  1NKP B;  1R05 A;  4F3L B;  5I4Z A;  2YPA B;  1MDY A;  2YPB A;  4AYA A; 
#chains in the Genus database with same CATH homology
 1NLW B;  1AM9 A;  4ATH A;  2QL2 B;  5I50 A;  3U5V A;  1MDY B;  4H10 A;  2YPB B;  5EYO A;  2LFH A;  4ATI A;  1A0A A;  3MUJ A;  2YPA A;  4F3L A;  1NKP A;  1UKL C;  1AN2 A;  1AN4 A;  1HLO A;  4ATK A;  4H10 B;  2MH3 A;  1NLW A;  2QL2 A;  1NKP B;  1R05 A;  4F3L B;  5I4Z A;  2YPA B;  1MDY A;  2YPB A;  4AYA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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